Publications

2023

215. Xu, R.; Liu, H.; Yuan, F.; Kim, S.; Kirpich, I.; McClain, C. J., Zhang, X. Lipid Wizard: a software for comprehensive two-dimensional liquid chromatography mass spectrometry-based lipid profiling. Anal. Chem. 2023, under revision.

214. Zhao, J.; Adiele, N.; Gomes, D.; Malovichko, M.; Conklin, D. J.; Ekuban, A.; Luo, J.; Gripshover, T.; Watson, W. H.; Banerjee, M.; Smith, M. L.; Rouchka, E. C.; Xu, R.; Zhang, X.; Cave, M. C.; O’Toole, T. E. Obesogenic polystyrene microplastic exposures disrupt the gut-liver-adipose axis and are ameliorated by the dietary anthrocyanin, delphinidin. Toxicol. Sci, 2023, in press.

213. Vatsalya, V.; Verster, J.; Sagaram, M.; Royer, A. J.; Hu, H.; Parthasarathy, R.; Schwandt, M. L.; Leggio, L.; Kong, M.; Ramchandani, V. A.; Feng, W.; Agrawal, R.; Zhang, X.; McClain, C. J. Novel paradigms for the gut-brain axis of alcohol withdrawal, withdrawal-associated depression, and craving in patients with alcohol use disorder. Frontiers in Psychiatry. 2023, 14:1203362. https://doi.org/10.3389/fpsyt.2023.1203362. (PMID: 37840804)

212. Warner, J. B.; Hardesty, J. E.; Song, Y. L.; Floyd, A. T.; Jebet, A.; He, L.; Zhang, X.; McClain, C. J.; Hammock, B. D., Warner, D. R., Kirpich, I. A. Hepatic transcriptome and its regulation following soluble epoxide hydrolase inhibition in alcohol-associated liver disease. Am. J. Pathol. 2023, in press. https://doi.org/10.1016/j.ajpath.2023.09.016 (PMID: 39725018)

211. Xu, R.; Vatsalya, V.; He, L.; Ma, X.; Feng, W.; McClain, C. J.; Zhang, X. Altered urinary tryptophan metabolites in alcohol-associated liver disease. Alcohol. Clin. Exp. Res. 2023, in press. https://doi.org/10.1111/acer.15148. (PMID: 37431708)

210. Sarkar, O. S.; Donninger, H.; Rayyan, N. A.; Chew, L. C.; Stamp, B.; Zhang, X.; Whitt, A.; Li, C.; Hall, M.; Mitchell, R. A.; Zippelius, A.; Eaton, J.; Chesney, J. A.; Yaddanapud, K. Monocytic MDSCs exhibit superior immune suppression via adenosine and enzymatic depletion of adenosine improves efficacy of immunotherapy. Sci. Adv. 2023, 9(26):eadg3736. https://doi.org/10.1126/sciadv.adg3736. (PMID: 37390211)

209. Piell, K. M.; Petri, B. J.; Head, K. Z.; Wahlang, B.; Xu, R.; Zhang, X.; Pan, J.; Rai, S. N.; de Silva, K.; Chariker, J. H.; Rouchka, E. C.; Tan, M.; Li, Y.; Cave, M. C., Klinge, C. M. Disruption of the mouse liver epitranscriptome by long-term aroclor 1260. Environ. Toxicol. Phar. 2023, 100:104138. https://doi.org/10.1016/j.etap.2023.104138. (PMID: 37137421)

208. Liu, S.; He, L.; Bannister, O.; Schnegelberger, R.; Vanderpuye, C.; Althouse, A.; Schopfer, F.; Wahlang, B.; Cave, M.; Monga, S. P. S.; Zhang, X.; Arteel, G.; Beier, J. Western diet unmasks transient low-level vinyl chloride-induced tumorigenesis; potential role of the (epi-)transcriptome. Toxicol. Appl. Pharmacol. 2023, 468:116514. https://doi.org/10.1016/j.taap.2023.116514. (PMID: 37061008)

207. Wise, J. T. F.; Yin, X.; Ma, X.; Zhang, X.; Hein, D. W. Stable isotope tracing reveals an altered fate of glucose in N-acetyltransferase 1 knockout breast cancer cells. Genes, 2023, 14(4), 843. https://doi.org/10.3390/genes14040843.

206. Zhu, X.; Zhang, X. Discretized skew-t mixture model for deconvoluting liquid chromatograph mass spectrometry data. Statistica Neerlandica 2023, 1-20. https://doi.org/10.1111/stan.12285.

205. Xu, R.; He, L.; Vatsalya, V.; Ma, X.; Kim, S.; Mueller, E. G.; Feng, W.; McClain, C. J.; Zhang, X. Metabolomics analysis of urine from patients with alcohol-associated liver disease reveals dysregulated caffeine metabolism. Am. J. Physiol-Gaster. L. 2023, 324(2), G142-G154. https://doi.org/10.1152/ajpgi.00228.2022. (PMID: 36513601, Journal cover)

204. Ding, C.; Shrestha, R.; Zhu, X.; Geller, D. A.; Wu, S.; Woeste, M.; Li, W.; Wang, H.; Yuan, F.; Xu, R.; Chariker, J.; Hu, X.; Li, H.; Tieri, D.; Zhang, H-G, Rouchka, E.; Mitchell, R.; Siskind, L.; Zhang, X.; Xu, X.; McMasters, K.; Yu, Y.; Yan, J. Inducing trained immunity in pro-metastatic macrophages to control tumor metastasis. Nat. Immunol. 2023, 24, 239-254. https://doi.org/10.1038/s41590-022-01388-8. (PMID: 36604547)

2022

203. He, L.; Vatsalya, V.; Ma, X.; Klinge, C.; Cave, M. C.; Feng, W.; McClain, C. J.; Zhang, X. Metabolic analysis of nucleosides/bases in the urine and serum of patients with alcohol-associated liver disease. Metabolites 2022, 12, 1187. https://doi.org/10.3390/metabo12121187. (PMID: 36557225)

202. Miralles-Pérez, B.; Nogués, M. R.; Sánchez-Martos, V.; Fortuño-Mar, À.; Ramos-Romero, S.; Torres, J.; Ponomarenko, J.; Amézqueta, S.; Zhang, X.; Romeu, M. Influence of dietary inulin on fecal microbiota, cardiometabolic risk factors, eicosanoids and oxidative stress in rats fed a high-fat diet. Foods 2022, 11, 4072. https://doi.org/10.3390/foods11244072. (PMID: 36553814)

201. Kumar, A.; Sundaram, K.; Teng, Y.; Mu, J.; Sriwastva, M. K.; Zhang, L.; Hood, J. L.; Yan, J.; Zhang, X.; Park, J. W.; Merchant, M. L.; Zhang, H-G. Ginger nanoparticles mediated induction of Foxa2 prevents high-fat diet-induced insulin resistance. Theranostics 2022, 12(3), 1388-1403. https://doi.org/10.7150/thno.62514. (PMID: 35154496)

200. Sundaram, K.; Mu, J.; Kumar, A.; Behera, J.; Lei, C.; Sriwastva, M. K.; Xu, F.; Dryden, G. W.; Zhang, L.; Chen, S.; Yan, J.; Zhang, X.; Park, J. W.; Merchant, M. L.; Tyagi, N.; Teng, Y.; Zhang, H-G. Garlic exosome-like nanoparticles reverse high-fat diet induced obesity via the gut/brain axis. Theranostics 2022, 12(3), 1220-1246. https://doi.org/10.7150/thno.65427. (PMID: 35154484)

199. Teng, Y.; Mu, J.; Xu, F.; Zhang, X.; Sriwastva, M. K.; Liu, Q. M.; Li, X.; Lei, C.; Sundaram, K.; Hu, X.; Zhang, L.; Park, J. W.; Hwang, J. Y.; Rouchka, E. C.; Zhang, X.; Yan, J.; Merchant, M. L.; Zhang, H-G. Gut bacterial isoamylamine promotes age-related cognitive dysfunction by promoting microglial cell death. Cell Host & Microbe 2022, 30(7), 944–960.e8. https://doi.org/10.1016/j.chom.2022.05.005. (PMID: 35654045)

198. Kim, S.; Kato, I.; Zhang, X. Comparative analysis of binary similarity measures for compound identification in mass spectrometry-based metabolomics. Metabolites 2022, 12(8), 694. https://doi.org/10.3390/metabo12080694. (PMID: 35893261)

197. Yan, K.; Mei, Z.; Zhao, J.; Prodhan, Md A. I.; Obal, D.; Katragadda, K.; Doelling, B.; Hoetker, D.; Posa, D. K.; He, L.; Yin, X.; Shah, J.; Pan, J.; Rai, S.; Lorkiewicz, P. K.; Zhang, X.; Liu, S.; Bhatnagar, A.; Baba, S. P. Integrated multilayer omics reveals the genomic, proteomic, and metabolic influences of histidyl dipeptides on the heart. J. Am. Heart Assoc. 2022, 0:e023868. https://doi.org/10.1161/jaha.121.023868. (PMID: 35730646)

196. Jiang, M.; Li, F.; Liu, Y.; Gu, Z.; Zhang, L.; Lee, J.; He, L.; Vatsalya, V.; Zhang, H-G.; Deng, Z.; Zhang, X.; Chen, S-Y.; Guo, L. G.; Barve, S.; McClain, J. C.; Feng, W. Probiotic-derived nanoparticles inhibit ALD through intestinal miR194 suppression and subsequent FXR activation. Hepatology 2022, Jun 11;10.1002/hep.32608. https://doi.org/10.1002/hep.32608. (PMID: 35689610)

195. Teng, Y.; Mu, J.; Xu, F.; Zhang, X.; Sriwastva, M. K.; Liu, Q. M.; Li, X.; Lei, C.; Sundaram, K.; Hu, X.; Zhang, L.; Park, J. W.; Hwang, J. Y.; Rouchka, E. C.; Zhang, X.; Yan, J.; Merchant, M. L.; Zhang, H.-G. Gut bacterial isoamylamine promotes age-related cognitive dysfunction by promoting microglial cell death. Cell Host & Microbe 2022, 30, 1-17. https://doi.org/10.1016/j.chom.2022.05.005. (PMID: 35654045)

194. Vatsalya, V.; Parthasarathy, R.; Verster, J. C.; Royer, A. C.; Sagaram, M.; Zamani, Z.; Hu, H.; Schwandt, M. L.; Leggio, L.; Kong, M.; Ramchandani, V. A.; Feng, W.; Zhang, X.; McClain, C. J. Illustration of a novel gut-brain axis of alcohol withdrawal, withdrawal-associated depression, craving and alcohol-severity index in alcohol use disorder patients. medRxiv 2022, DOI: 10.1101/2022.05.15.22275115.

193. Miller, H. A.; Rai, S. N.; Yin, X.; Zhang, X.; Chesney, J. A.; van Berkel, V. H., Frieboes, H. B. Lung cancer metabolomic data from tumor core biopsies enables risk-score calculation for progression-free and overall survival. Metabolomics 2022, 14, 18(5):31. https://doi.org/10.1007/s11306-022-01891-x. (PMID: 35567637)

192. Chen, X.; Cai, Y.; Hu, X.; Ding, C.; Ke, L.; Zhang, X.; Chen, F.; Yan, J. Differential metabolic requirement governed by transcription factor c-Maf dictates γδT17 effector functionality in mice and humans. Sci. Adv. 2022, 8(21):eabm9120. https://doi.org/10.1126/sciadv.abm9120. (PMID: 35613277)

191. Sun, R.; Lei, C.; Chen, L.; He, L.; Guo, H.; Zhang, X.; Feng, W.; Yan, J.; McClain, C. J.; Deng, Z. B. Alcohol-driven metabolic reprogramming promotes development of RORγt-deficient thymic lymphoma. Oncogene 2022, 41(16), 2287-2302. https://doi.org/10.1038/s41388-022-02257-2. (PMID: 35246617)

190. Sriwastva, M. K.; Deng, Z.; Wang, B.; Teng, Y.; Kumar, A.; Sundaram, K.; Mu, J.; Lei, C.; Dryden, G.W.; Xu, F.; Zhang, L.; Yan, J.; Zhang, X.; Park, J.; Merchant, M.; Egilmez, N.; Zhang, H. Exosome-like nanoparticles from Mulberry bark prevent DSS-induced colitis via the AhR/COPS8 pathway. EMBO Rep. 2022, 23(3):e53365. https://doi.org/10.15252/embr.202153365. (PMID: 34994476)

2021

189. Kumar1, A.; Ren, Y.; Sundaram, K.; Mu, J.; Sriwastva, M.K.; Dryden, G.W.; Lei, C.; Zhang, L.; Yan, J.; Zhang, X.; Park, J.W.; Merchant, M.L.; Teng, Y.; Zhang, H-G. miR-375 prevents high-fat diet-induced insulin resistance and obesity by targeting the aryl hydrocarbon receptor and bacterial tryptophanase (tnaA) gene. Theranostics 2021, 11(9), 4061-4077. https://doi.org/10.7150/thno.52558. (PMID: 33754048)

188. Song, M.; Yuan, F.; Li, X.; Ma, X.; Yin, X.; Rouchka, E.; Zhang, X.; Deng, Z.; Prough, R.; McClain, C. J. Analysis of sex differences in dietary copper-fructose interaction-induced alterations of gut microbial activity in relation to hepatic steatosis. Biol. Sex Differ. 2021, 12:3. https://doi.org/10.1186/s13293-020-00346-z. (PMID: 33407877)

187. Morrissey, S. M.; Zhang, F.; Ding, C.; Montoya-Durango, D. E.; Hu, X.; Yang, C.; Wang, Z.; Yuan, F.; Fox, M.; Zhang, H.; Guo, H.; Tieri, D.; Kong, M.; Watson, C. T.; Mitchell, R. A.; Zhang, X.; McMasters, K. M.; Huang, J.; Yan, J. Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through metabolic reprogramming. Cell Metabolism 2021, 5, 33(10), 2040-2058. https://doi.org/10.1016/j.cmet.2021.09.002. (PMID: 34559989)

186. Warner, J.; Hardesty, J.; Song, Y.; Sun, R.; Deng, Z.; Xu, R.; Yin, X.; Zhang, X.; McClain, C. J.; Warner, D.; Kirpich, I. Fat-1 transgenic mice with augmented n3-polyunsaturated fatty acids are protected from liver injury caused by acute-on-chronic ethanol administration. Front. Pharmacol. 2021, 12:711590. https://doi.org/10.3389/fphar.2021.711590. (PMID: 34531743)

185. Klinge, C.; Piell, K.; Petri, B.; He, L.; Zhang , X.; Pan, J.; Rai, S.; Andreeva, K.; Rouchka, E.; Wahlang, B.; Beier, J.; Cave, M. Polychlorinated biphenyls and high fat diet modify the global epitranscriptomic landscape in mouse liver. Environ. Epigenet. 2021, 7(1), 1-12. https://doi.org/10.1093/eep/dvab008. (PMID: 34548932)

184. Chen, K.; Tsai, S.; Zhang, X.; Zeng, C.; Yang, H. The investigation of the volatile metabolites of lung cancer from the microenvironment of malignant pleural effusion. Sci. Rep. 2021, 11, 13585. https://doi.org/10.1038/s41598-021-93032-y. (PMID: 34193905)

183. Lei, C.; Teng, Y.; He, L.; Sayed, M.; Mu, J.; Xu, F.; Zhang, X.; Kumar, A.; Sundaram, K.; Sriwastva, M.; Zhang, L.; Yan, J.; Park, J.; Merchant, M.; Zhang, X.; Zhang, H-G. Lemon exosome-like nanoparticles enhance stress survival of gut bacteria by RNase P mediated specific tRNA decay. iScience 2021, 24, 102511. https://doi.org/10.1016/j.isci.2021.102511. (PMID: 34142028)

182. Teng, Y., Xu, F., Zhang, X., Mu, J., Sayed, M., Hu, X., Lei, C., Sriwastva, M., Kumar, A., Sundaram, K., Zhang, L., Park, J. J. W., Chen, S., Zhang, S., Yan, J., Merchant, M. L., Zhang, X., McClain, C. J., Wolfe, J. K., Adcock, R. S., Chung, D., Palmer, K. E., Zhang, H. Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12. Mol. Ther. 2021, 29 (8), 2424-2440. https://doi.org/10.1016/j.ymthe.2021.05.005. (PMID: 33984520)

181. Miller, H.A.; Yin, X.; Smith, S.A.; Hu, X.; Zhang, X.; Yan, J.; Miller, D.M.; van Berkel, V.H.; Frieboes, H.B. Evaluation of disease staging and chemotherapeutic response in non-small cell lung cancer from patient tumor-derived metabolomic data. Lung Cancer 2021, 156, 20-30. https://doi.org/10.1016/j.lungcan.2021.04.012. (PMID: 33882406)

180. Gu, Z.; Li, F.; Liu, Y.; Jiang, M.; Zhang, L.; He, L.; Wilkey, D. W.; Merchant, M.; Zhang, X.; Deng, Z.; Chen, S.; Barve, S.; McClain, C. J.; Feng, W. Exosome-like nanoparticles from Lactobacillus rhamnosus GG protect against alcoholic liver disease through intestinal AhR in mice. Hepatology Commun. 2021, 5(5), 846-864. https://doi.org/10.1002/hep4.1679. (PMID: 34027273)

179. He, L.; Vatsalya, V.; Ma, X.; Zhang, J.; Yin, X.; Kim, S.; McClain, C. J.; Zhang, X. Metabolic profiling of bile acids in urine of patients with alcohol associated liver disease. Hepatology Commun. 2021, 5(5), 798-811. https://doi.org/10.1002/hep4.1671. (PMID: 34027270)

178. Vatsalya, V.; Li, F.; Frimodig, J.; Gala, K. S.; Srivastava, S.; Kong, M.; Ramchandani, V. A.; Feng, W.; Zhang, X.; McClain, C. J. Therapeutic prospects for Th-17 cell immune storm syndrome and neurological symptoms in COVID-19: thiamine efficacy and safety, in-vitro evidence and pharmacokinetic profile. Front. Pharmacol. 2021, 11:598128. https://doi.org/10.1101/2020.08.23.20177501. (PMID: 32869036)

177. Kumar, A.; Sundaram, K.; Mu, J.; Dryde, G.; Sriwastva, M.; Lei, C.; Zhang, L.; Qiu, X.; Xu, F.; Yan, J.; Zhang, X.; Park, J.; Merchant, M.; Bohler, H.; Wang, B.; Zhang, S.; Qin, C.; Xu, Z.; Han, X.; McClain, C. J.; Teng, Y.; Zhang, H-G. High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance. Nat. Commun. 2021, 12(1):213. https://doi.org/10.1038/s41467-020-20500-w. (PMID: 33431899)

176. Ren, D.; He, Z.; Fedorova, J.; Zhang, J.; Wood, E.; Zhang, X.; Kang, D. E.; Ji, L. Sestrin2 maintains OXPHOS integrity to modulate cardiac substrate metabolism during ischemia and reperfusion. Redox Biol. 2021, 28, 1010824. https://doi.org/10.1016/j.redox.2020.101824. (PMID: 33316744)

175. Prodhan, M. A. I.; McClain, C. J.; Zhang, X. Comprehensive two-dimensional gas chromatography mass spectrometry-based metabolomics. In: Hu S. (eds) Cancer Metabolomics. Advances in Experimental Medicine and Biology 2021, 1280, 57-67. Springer, Cham. https://doi.org/10.1007/978-3-030-51652-9_4. (PMID: 33791974)

2020

174. Lei, C., Mu, J., Teng, Y., He, L., Xu, F., Zhang, X., Sundaram, K., Kumar, A., Sriwastva, M. K., Lawrenz, M. B., Zhang, L., Yan, J., Feng, W., McClain, C. J., Zhang, X., Zhang, H-G. Lemon exosome-like nanoparticles-manipulated probiotics protect mice from C. diff Infection. iScience 2020, 23(10):101571. https://doi.org/10.1016/j.isci.2020.101571. (PMID: 33083738)

173. Yuan, F.; He, L.; Feng, W.; McClain, C. J.; Zhang, X. High-throughput profiling of long chain fatty acids and oxylipins by LC-MS. Current Trends in Mass Spectrometry 2020, 18(4), 28-34.

172. Yuan, F.; Kim, S.; Yin, X.; Zhang, X.; Kato, I. Integrating two-dimensional gas and liquid chromatography mass spectrometry for untargeted colorectal cancer metabolomics: a proof of principle study. Metabolites 2020, 10(9), e343. https://doi.org/10.3390/metabo10090343. (PMID: 32854360)

171. Fleissig, E.; Appenbrick, E.; Zhang, X.; Barr, C. C. Vitamin analysis comparison study. Am. J. Ophthalmol. 2020, 222, 202-205. https://doi.org/10.1016/j.ajo.2020.08.028. (PMID: 32828875)

170. Conroy, L.; Lorkiewicz, P.; He, L.; Yin, X.; Zhang, X.; Rai, S.; Clem, B. Palbociclib treatment alters nucleotide biosynthesis and glutamine dependency in A549 cells. Cancer Cell Int. 2020, 20:280. https://doi.org/10.1186%2Fs12935-020-01357-x. (PMID: 32624705)

169. Zhao, J.; Conklin, D.; Guo, Y.; Zhang, X.; Obal, D.; Guo, L.; Jagatheesan, G.; Katragadda, K.; He, L.; Yin, X.; Prodhan, A. M.; Shah, J.; Hoetker, D.; Kumar, A.; Kumar, V.; Wempe, M.; Bhatnagar, A.; Baba, S. Cardiospecific overexpression of ATPGD1 increases histidine dipeptide levels and prevents myocardial ischemia-reperfusion injury. J. Am. Heart Assoc. 2020, 9(12):e015222. https://doi.org/10.1161%2FJAHA.119.015222. (PMID: 32515247)

168. Liu, Y.; Chen, K.; Li, F.; Gu, Z.; Liu, Q.; He, L.; Shao, T.; Song, Q.; Zhu, F.; Zhang, L.; Jiang, M.; Zhou, Y.; Barve, S.; Zhang, X.; McClain, C. J.; Feng, W. Probiotic LGG prevents liver fibrosis through inhibiting hepatic bile acid synthesis and enhancing bile acid excretion in mice. Hepatol. 2020, 71(6), 2050-2066. https://doi.org/10.1002%2Fhep.30975. (PMID: 31571251)

167. Liu, M.; Tong, Z.; Ding, C.; Luo, F.; Wu, S.; Albeituni, S.; He, L.; Hu, X.; Tieri, D.; Rouchka, E. C.; Hamada, M.; Takahashi, S.; Gibb, A. G.; Kloecker, G.; Zhang, H.; Bousamra II, M.; Hill, B. G.; Zhang, X.; Yan, J. Transcription factor c-Maf is a molecular checkpoint that controls immune suppression by programming macrophages in lung cancer. J. Clin. Invest. 2020, 130(4), 2081-2096. https://doi.org/10.1172%2FJCI131335. (PMID: 31945018)

166. Conroy, L.R.; Dougherty, S.; Kruer, T.; Metcalf, S.; Lorkiewicz, P.; He, L.; Yin, X.; Zhang, X.; Arumugam, S.; Young, L.; Sun, R.; Clem, B. Loss of Rb1 enhances glycolytic metabolism in Kras-driven lung tumors in vivo. Cancers 2020, 12(1), 237-253. https://doi.org/10.3390/cancers12010237. (PMID: 31963621)

165. Li, Z.; Kim, S.; Zhong, S.; Zhong, Z.; Kato, I.; Zhang, X. Coherent point drift peak alignment algorithms using distance and similarity measures for analysis of comprehensive two-dimensional gas chromatography mass spectrometry data. J. Chemometrics 2020, 34(8):e3236. https://doi.org/10.1002/cem.3236. (PMID: 33505107)

164. Yuan, F.; Harder, J.; Yin, X.; Zhang, X.; Kosiewicz, M. M. Effects of androgen depletion in mouse feces analyzed using multiple metabolic platforms. J. Proteome Res. 2020, 19, 667-676. (Selected as a journal cover page)

163. Liu, Q.; Liu, Y.; Li, F.; Gu, Z.; Liu, M.; Shao, T.; Zhang, L.; Zhou, G.; Pan, C.; He, L.; Cai, J.; Zhang, X.; Barve, S.; McClain, C. J.; Chen, Y.; Feng, W. Probiotic culture supernatant improves metabolic function through FGF21-adiponectin pathway in mice. J. Nutr. Biochem. 2020, 75, 108256. https://doi.org/10.1016/j.jnutbio.2019.108256. (PMID: 31760308)

2019

162. Sundaram, K.; Miller, D. P.; Kumar, A.; Teng, Y.; Sayed, M.; Mu, J.; Lei, C.; Sriwastva, M. K.; Zhang, L.; Jun, Y.; Merchant, M. L.; He, L.; Yuan, F.; Zhang, X.; Park, J. W.; Lamont, R. J.; Zhang, H. Plant-derived exosomal nanoparticles inhibit pathogenicity of Porphyromonas gingivalis. iScience 2019, 21, 308-327. https://doi.org/10.1016/j.isci.2019.10.032. (PMID: 31678913)

161. Warner, D. R.; Warner, J. B.; Hardesty, J. E.; Song, Y. L.; King, T. N.; Kang, J. X.; Chen, C.; Xie, S.; Yuan, F.; Prodhan, A. M. I.; Ma, X.; Zhang, X.; Rouchka, E. C.; Whitlock, J.; Li, E. C.; Wang, G.P.; McClain, C. J.; Kirpich, I. A. Decreased ω6/ω3 PUFA ratio attenuates ethanol-induced alterations in intestinal homeostasis, microbiota and liver injury. J. Lipid Res. 2019, 60, 2034-2049. https://doi.org/10.1194/jlr.ra119000200. (PMID: 31586017)

160. Lorkiewicz1, P. K.; Gibb, A. A.; Rood, B. R.; He, L.; Zheng, Y.; Clem, B. F.; Zhang, X.; Hill, B. G. Integration of flux measurements and pharmacological controls to optimize stable isotope-resolved metabolomics workflows and interpretation. Sci. Rep-UK 2019, 9:13750. https://doi.org/10.1038/s41598-019-50183-3. (PMID: 31548575)

159. Young, J. L.; Yan, X.; Xu, J.; Yin, X.; Zhang, X.; Arteel, G. E.; Barnes, G. N.; States, C. J.; Watson, W.; Kong, M.; Cai, L.; Freedman, J. H. Cadmium and high-fat diet disrupt renal, cardiac and hepatic essential metals. Sci. Rep-UK 2019, 9:14675. https://doi.org/10.1038/s41598-019-50771-3. (PMID: 31604971)

158. He, L.; Li, F.; Yin, X.; Bohman, P.; Kim, S.; McClain, C. J.; Feng, W.; Zhang, X. Profiling of Polar Metabolites in Mouse Feces Using Four Analytical Platforms to Study the Effects Of Cathelicidin-Related Antimicrobial Peptide in Alcoholic Liver Disease. J. Proteome. Res. 2019, 18, 7, 2875-2884. https://doi.org/10.1021/acs.jproteome.9b00181. (PMID: 31188604)

157. Prodhan, A.I.; Shi, B.; Song, M.; He, L.; Yuan, F.; Yin, X.; Bohman, P.; McClain, C. J.; Zhang, X. Integrating comprehensive two-dimensional gas chromatography mass spectrometry and two-dimensional liquid chromatography mass spectrometry for untargeted metabolomics. Analyst 2019, 144, 4331-4341. https://doi.org/10.1039/c9an00560a. (PMID: 31192319)

156. He, L.; Wei, X.; Ma, X.; Yin, X.; Song, M.; Donninger, H.; Yaddanapudi, K.; McClain, C. J.; Zhang, X. Simultaneous quantification of nucleosides and nucleotides from biological samples. J. Am. Soc. Mass Spectrom. 2019, 30(6), 987-1000. https://doi.org/10.1007/s13361-019-02140-7. (PMID: 30847833)

155. Chakravarty, S.; Mandal, R. K.; Duff, M. L.; Yuan, F.; Zhang, X.; Schmidt, N. W. Intestinal short-chain fatty acid composition does not explain gut microbiota-mediated effects on malaria severity. PLoS ONE 2019, 14(2):e0214449. https://doi.org/10.1371/journal.pone.0214449. (PMID: 30917184)

154. Kim, S.; Yin, X.; Prodhan, A. M. I.; Zhang, X.; Zhong, Z.; Kato, I. Global plasma profiling for colorectal cancer associated volatile organic compounds: a proof of principle study. J. Chromatogr. Sci. 2019, 57, 385-396. https://doi.org/10.1093/chromsci/bmz011. (PMID: 30796770)

153. Roumani, A.; Madkour, A.; Ouzzani, M.; McGrew, T.; Omran, E.; Zhang, X. BioNetApp: an interactive visual data analysis platform for molecular expressions. PLoS ONE 2019, 14(2):e0211277. https://doi.org/10.1371/journal.pone.0211277. (PMID: 30794548)

152. Shahrajooihaghighi, A.; Hichem, F.; Zhang, X.; Wei, X.; Shi, B.; McClain, C. J. Ensemble feature selectin for biomarker discovery in mass spectrometry-based metabolomics. Proceedings of the 34th ACM/SIGAPP Symposium on Applied Computing (SAC’19). Page 19-24. April 8-12, 2019. Limassol, Cyprus. https://dl.acm.org/citation.cfm?id=3297283 [Peer-reviewed conference paper]

151. Trabelsi, A.; Shi, B.; Wei, X.; Frigui, H.; Zhang, X.; McClain, C. J.; Shahrjooihaghighi, A. Molecule specific normalization for protein and metabolite biomarker discovery. Proceedings of the 34th ACM/SIGAPP Symposium on Applied Computing (SAC’19). Pages 25-31. April 8-12, 2019. Limassol, Cyprus. https://dl.acm.org/citation.cfm?id=3297284 [Peer-reviewed conference paper]

2018

150. Shao, T.; Zhao, C.; Li, F.; Gu, Z.; Liu, L.; Zhang, L.; Wang, Y.; He, L.; Liu, Y.; Liu, Q.; Chen, Y.; Donde, H.; Wang, R.; Jala, R. J.; Barve, S.; Chen, S-Y.; Zhang, X.; Chen, Y.; McClain, C. J.; Feng, W. Intestinal HIF-1α deletion exacerbates alcoholic liver disease through inducing intestinal dysbiosis and barrier dysfunction. J. Hepatol. 2018, 69(4), 886-895. https://doi.org/10.1016/j.jhep.2018.05.021. (PMID: 29803899)

149. Prodhan, A.I.; Yin, X.; Kim, S.; McClain, C. J.; Zhang, X. Surface fitting for calculating the second dimension retention index in comprehensive two-dimensional gas chromatography mass spectrometry. J. Chromatogr. A. 2018, 1539, 62-70. https://doi.org/10.1016/j.chroma.2018.01.049. (PMID: 29395161)

148. Warner, D. R.; Liu, H.; Dastidar, S.G.; Warner, J. B.; Prodhan, A.I.; Yin, X.; Zhang, X.; Feldstein, A.E.; Gao, B.; Prough, R.A.; McClain, C. J.; Kirpich, I. A. Ethanol and unsaturated dietary fat induce unique patterns of hepatic ω-6 and ω-3 PUFA oxylipins in a mouse model of alcoholic liver disease. PLoS ONE 2018, 13(9): e0204119. https://doi.org/10.1371/journal.pone.0204119. (PMID: 30256818)

147. Song, M.; Li, X.; Zhang, X.; Shi, H.; Vos, M.; Wei, X.; Wang, Y.; Gao, H.; Rouchka, E. C.; Yin, X.; Zhou, Z.; Prough, R.; Cave, M.; McClain, C. J. Dietary copper-fructose interactions alter gut microbial activity in male rats. Am. J. Physiol. –Gastr. L. 2018, 314, G119-G130. https://doi.org/10.1152/ajpgi.00378.2016. (PMID: 29025734)

146. He, L.; Prodhan, A.I.; Yuan, F.; Yin, X.; Lorkiewicz, P. K.; Wei, X.; Feng, W.; McClain, C.; Zhang, X. Simultaneous quantification of straight-chain and branched-chain short fatty acids by gas chromatography mass spectrometry. J. Chromatogr. B. 2018, 1092, 359-367. https://doi.org/10.1016/j.jchromb.2018.06.028. (PMID: 29936372)

145. Prodhan, A. I.; Sleman, A. A.; Kim, S.; McClain, C. J.; Zhang, X. Generalization of reference system for calculating the second dimension retention index in GC×GC-MS. J. Anal. Test. 2018, 3, 263-273.

144. Gao, Y.; Gao, L.; Tian, J.; Qin, X.; Zhang, X. A network pharmacology approach to decipher the mechanisms of anti-depression of Xiaoyaosan formula. World J. Tradit. Chin. Med. 2018, 4, 147-162.

143. Zhao, F.; Chang, Y.; Gao, L.; Qin, X.; Du, G.; Zhang, X.; Zhou, Y. Protective effects of Scutellaria baicalensis Georgi extract on D-galactose induced aging rats. Metab. Brain Dis. 2018, 33(5), 1401-1412. https://doi.org/10.1007/s11011-018-0229-z. (PMID: 29855978)

142. Gao, X.; Liang, M.; Fang, Y.; Zhao, F.; Tian, J.; Zhang, X.; Qin, X. Deciphering the differential effective and toxic responses of Bupleuri Radix following the induction of chronic unpredictable mild stress and in healthy rats based on serum metabolic profiles. Front. Pharmacol. 2018, 8:995. https://doi.org/10.3389/fphar.2017.00995. (PMID: 29379441)

2017

141. Wei, X.; Shi, B.; Koo, I.; Yin, X.; Lorkiewicz, P.; Suhail, H.; Rattan, R.; Giri, S.; McClain, C. J.; Zhang, X. Analysis of stable isotope assisted metabolomics data acquired by GC-MS. Analytica Chimica Acta 2017, 980, 25-32. https://doi.org/10.1016%2Fj.aca.2017.05.002. (PMID: 28622800).

140. Kim, S.; Jang, H.; Koo, I.; Lee, J.; Zhang, X. Normal-Gamma-Bernoulli peak detection for analysis of comprehensive two-dimensional gas chromatography mass spectrometry data. Comput. Stat. Data Anal. 2017, 105, 96-111. https://doi.org/10.1016%2Fj.csda.2016.07.015. (PMID: 27667882)

139. Wei, X.; Lorkiewicz, P.; Salabei, J. K.; Shi, B.; Hill, B. G.; Kim, S.; McClain, C. J.; Zhang, X. Analysis of stable isotope assisted metabolomics data acquired by high resolution mass spectrometry. Anal. Methods 2017, 9, 2275-2283. http://dx.doi.org/10.1039/C7AY00291B. (PMID: 28622800)

138. Gibb, A. A.; Lorkiewicz, P. K.; Zheng, Y.; Zhang, X.; Epstein, P.N.; Jones, S.P.; Bhatnagar, A.; Hill, B. G. Integration of flux measurements to resolve changes in anabolic and catabolic metabolism in cardiac myocytes. Biochem. J. 2017, 474(16), 2785-2801. https://doi.org/10.1042/bcj20170474. (PMID: 28706006)

137. Zhou, Y.; Zhao, F.; Gao, L.; Du, G.; Zhang, X.; Qin, X. Licorice extract attenuates brain aging of D-galactose induced rats through inhibition of oxidative stress and attenuation of neuronal apoptosis. RSC Advances 2017, 7, 47758-47766. https://doi.org/10.1039/C7RA07110H.

136. Zhou, Y.; Yan, M.; Gao, L.; Zhang, Q.; Qin, X.; Zhang, X.; Du, G. Metabonomics approach to assessing the metabolism variation and gender gap of Drosophila melanogaster in aging process. Experimental Gerontology 2017, 98, 110-119. https://doi.org/10.1016/j.exger.2017.07.020. (PMID: 28811139)

135. Li, J.; Gao, W.; Gao, J.; Li, H.; Zhang, X.; Qin, X.; Li, Z. Metabolomics reveal the protective effect of Farfarae Flos against asthma using an OVA-induced rat model. RSC Adv. 2017, 7 (63), 39929-39939. https://doi.org/10.1039/C7RA05340A.

134. Ma, K.; Miao, Y.; Li, X.; Zhou, Y.; Gao, X.; Zhang, X.; Chao, J.; Qin, X. Discovery of 1,3-diyne compounds as novel and potent antidepressant agents: synthesis, cell-based assay and behavioral studies. RSC Adv. 2017, 7, 16005-16014. https://doi.org/10.1039/C7RA01268C.

133. Zhou, Y.; Li, X.; Gong, W.; Tian, J.; Gao, X.; Gao, L.; Zhang, X.; Du, G.; Qin, X. Protective effect of isoliquiritin against corticosterone-induced neurotoxicity in PC12 cells. Food & Function 2017, 8, 1235-1244. https://doi.org/10.1039/c6fo01503d. (PMID: 28229156)

132. Ma, K.; Miao, Y.; Gao, X.; Chao, J.; Zhang, X.; Qin, X. Total syntheses of bupleurynol and its analog. Chin. Chem. Lett. 2017, 28(5), 1035-1038. https://doi.org/10.1016/j.cclet.2016.11.032.

131. Shahrjooihaghighi, A.; Frigui, H.; Zhang, X.; Wei, X.; Shi, B.; Trabelsi, A. An ensemble feature selection method for biomarker discovery. IEEE International Symposium on Signal Processing and Information Technology. University of Deusto – Auditorio Icaza. Dec. 18-20, 2017. Bilbao, Spain. Page 416-421. https://ieeexplore.ieee.org/document/8388679 (PMID: 30887013)

2016

130. Deng, B.; Kim, S.; Li, H.; Heath, E.; Zhang, X. Global peak alignment for comprehensive two-dimensional gas chromatography mass spectrometry using point matching algorithms. J. Bioinf. Comput. Biol. 2106, 9:1650032. https://doi.org/10.1142/s0219720016500323. (PMID: 27650662)

129. Tian, J.; Xia, X.; Wu, Y.; Zhao, L.; Xiang, H.; Du, G.; Zhang, X.; Qin, X. Discovery, screening and evaluation of a plasma biomarker panel for subjects with psychological suboptimal health state using ¹H-NMR-based metabolomics profiles. Sci. Rep-UK 2016, 21, 6:33820. https://doi.org/10.1038/srep33820. (PMID: 27650680)

128. Salabei, J. K.; Lorkiewicz, P. K.; Mehra, P.; Gibb, A. A.; Haberzettl, P.; Hong, K.U.; Wei, X.; Zhang, X.; Li, Q.; Wysoczynski, M.; Bolli, R.; Bhatnagar, A.; Hill, B. G. Type 2 diabetes dysregulates glucose metabolism in cardiac progenitor cells. J. Biol. Chem. 2016, 26, 13634-13648. https://doi.org/10.1074/jbc.m116.722496. (PMID: 27151219)

127. Carlisle, S.M.; Trainor, P.J.; Yin, X.; Doll, M.A.; States, J. C.; Zhang, X.; Hein, D. W. Untargeted polar metabolomics of transformed MDA-MB-231 breast cancer cells expressing varying levels of human arylamine N-acetyltransferase 1. Metabolomics 2106, 12:111. https://doi.org/10.1007/s11306-016-1056-z. (PMID: 27872580)

126. Wang, S.; Luo, M.; Zhang, Z.; Gu, J.; Chen, J.; Payne, K. M.; Tan, Y.; Wang, Y.; Yin, X.; Zhang, X.; Liu, G. C.; Wintergerst, K.; Liu, Q.; Zheng, Y.; Cai, L. Zinc deficiency exacerbates while zinc supplement attenuates cardiac hypertrophy in high-fat diet-induced obese mice through modulating p38 MAPK-dependent signaling. Toxicol Lett. 2016, 258:134-46. https://doi.org/10.1016/j.toxlet.2016.06.020. (PMID: 27346292)

125. Liu, R.; Wu, D.; Zhang, X.; Kim, S. Compound identification using penalized linear regression in metabolomics. J. Mod. Appl. Stat. Meth. 2016, 15(1), 373-388. https://doi.org/10.22237/jmasm/1462076340. (PMID: 27212894)

124. Koo, I.; Kim, S.; Shi, B.; Lorkiewicz, P.; Song, M.; McClain, C. J.; Zhang, X. EIder: a compound identification tool for gas chromatography-mass spectrometry data. J. Chromatogr. A 2016, 1448, 107-114. https://doi.org/10.1016/j.chroma.2016.04.064. (PMID: 27131963)

123. Chung, D.; Golden, J. E.; Adcock, R. S.; Chu, Y.; Sotsky, J. B.; Cramer, D. E.; Chilton, P. M.; Song, C.; Anantpadma, M.; Schroeder, C. E.; Prodhan, A.M. I.; Yin, X.; Zhang, X. Discovery of a broad-spectrum antiviral compound that inhibits pyrimidine biosynthesis and establishes a type 1 interferon-independent antiviral state. Antimicrob. Agents Chemother. 2106, 60(8), 4552-4562. https://doi.org/10.1128/aac.00282-16. (PMID: 27185801)

122. Luo, M.; Luo, P.; Zhang, Z.; Payne, K.; Watson, S.; Wu, H.; Tan, Y.; Ding, Y.; Sun, W.; Yin, X.; Zhang, X.; Liu, G.; Wintergerst, K.; Miao, L.; Cai, L. Zinc delays the progression of obesity-related glomerulopathy in mice via down-regulating P38 MAPK-mediated inflammation. Obesity 2016, 24(6), 1244-1256. https://doi.org/10.1002/oby.21463. (PMID: 27028368)

121. Kirpich, I. A.; Petrosino, J.; Ajami, N.; Feng, W.; Wang, Y.; Liu, Y.; Beier, J. I.; Barve, S. S.; Yin, X.; Wei, X.; Zhang, X.; McClain, C. J. Saturated and unsaturated dietary fats differentially modulate ethanol-induced changes in gut microbiome and metabolome in a mouse model of alcoholic liver disease. Am. J. Pathol. 2016, 186(4), 765-776. https://doi.org/10.1016/j.ajpath.2015.11.017. (PMID: 27012191)

120. Zhang, J.; Xia, Y.; Zheng, H.; Wang, B.; Zhang, X.; Chen, P. Combine multiple mass spectral similarity measures for compound identification. Int. J. Data Mining and Bioinformatics 2016, 15(1), 84-100. https://doi.org/10.1504/IJDMB.2016.076018.

2015

119. Wei, X.; Song, M.; Yin, X.; Schuschke, D. A.; McClain, C. J.; Zhang, X. Effects of dietary different doses of copper and high fructose feeding on rat fecal metabolome. J. Proteome Res. 2015, 14(9), 4050-4058. https://doi.org/10.1021/acs.jproteome.5b00596. (PMID: 26216400)

118. Shi, X.; Wei, X.; Yin, X.; Wang, Y.; Zhang, M.; Zhao, C.; Zhao, H.; McClain, C. J.; Feng, W.; Zhang, X. Hepatic and fecal metabolomic analysis of the effects of Lactobacillus rhamnosus GG on alcoholic fatty liver disease in mice. J. Proteome Res. 2015, 14, 1174-1182. https://doi.org/10.1021/pr501121c. (PMID: 25592873)

117. Winnike, J.; Wei, X.; Knagge, K.J.; Colman, S.D.; Gregory, S.G.; Zhang, X. Comparison of GC-MS and GC×GC-MS in the analysis of human serum samples for biomarker discovery. J. Proteome Res. 2015, 14, 1810-1817. https://doi.org/10.1021/pr5011923. (PMID: 25735966)

116. Zhong, W.; Li, Q.; Sun, Q.; Zhang, W.; Zhang, J.; Sun, X.; Yin, X.; Zhang, X.; Zhou, Z. Preventing gut leakiness and endotoxemia contributes to the protective effect of zinc on alcohol-induced steatohepatitis in rats. J. Nutr. 2015, 145(12), 2690-2698. https://doi.org/10.3945/jn.115.216093. (PMID: 26468492)

115. Song, M.; Schuschke, D. A.; Zhou, Z.; Zhong, W.; Zhang, J.; Zhang, X.; Wang, Y.; McClain, C. J. Kupffer cell depletion protects against the steatosis, but not the liver damage, induced by marginal copper, high fructose diet in male rats. Am. J. Physiol. –Gastr. L. 2015, 308(11), 934-945. https://doi.org/10.1152/ajpgi.00285.2014. (PMID: 25813056)

114. Kim, S.; Zhang, X. Discovery of false identification using similarity difference in GC-MS based metabolomics. J. Chemometrics 2015, 29(2), 80-86. https://doi.org/10.1002/cem.2665. (PMID: 25937705)

113. Miskovic, F.M.; Couetil, L.; Riley, C.; Zhang, X.; Adamec, J.; Raskin, R. Secretoglobin and transferrin expression in bronchoalveolar lavage fluid of horses with chronic respiratory disease. J. Vet. Intern. Med. 2015, 29(6), 1692-1699. https://doi.org/10.1111/jvim.13604. (PMID: 26332291)

112. Phillips, M.; Cataneo, R.; Chaturvedi, A.; Kaplan, P.; Libardoni, M.; Mundada, M.; Patel, U.; Thrall, K.; Zhang, X. Breath biomarkers of whole-body gamma irradiation in the Göttingen minipig. Health Phys. 2015, 108(5), 538-546. https://doi.org/10.1097/hp.0000000000000272. (PMID: 25811151)

111. Tian, J.; Liu, C.; Xiang, H.; Zheng, X.; Peng, G.; Xiang Zhang, X.; Du, G.; Qin, X. Investigation on the antidepressant effect of sea buckthorn seed oil through the GC-MS-based metabolomics approach coupled with multivariate analysis. Food Funct. 2015, 6, 3585-3592. https://doi.org/10.1039/c5fo00695c. (PMID: 26328874)

110. Kim, S.; Lee, J.; Jang, H.; Zhang, X. Metabolic network construction using ensemble algorithms. The First International Workshop on Bioinformatics. Dec. 3-5, 2015. New York City, NY, USA. [Conference paper].

2014

109. Wei, X.; Shi, X.; Kim, S.; Patrick, J. S.; Binkley, J.; Kong, M.; McClain, C. J.; Zhang, X. Data dependent chromatographic peak model-based spectrum deconvolution for analysis of LC-MS data. Anal. Chem. 2014, 86, 2156−2165. (PMID: 24533635)

108. Shi, X.; Wei, X.; Koo, I.; Schmidt, R. H.; Yin, X.; Vaughn, A.; Kim, S.; McClain, C. J.; Arteel, G. E.; Zhang, X.; Watson, W. H. Metabolomic analysis of the effects of chronic arsenic exposure in a mouse model of diet-induced fatty liver disease. J. Proteome Res. 2014, 13, 547−554. (PMID: 24328084; PMCID: PMC3946282)

107. Wei, X.; Koo, I.; Kim, S.; Zhang, X. Compound identification in GC-MS by simultaneously evaluating mass spectrum and retention index. Analyst 2014, 139 (10), 2507 - 2514. (PMID: 24665464)

106. Kim, S.; Ouyang, M.; Shen, C.; Zhang, X. A new method of peak detection for analysis of comprehensive two-dimensional gas chromatography mass spectrometry data. Ann. Appl. Stat. 2014, 8, 1209-1231. (PMID: 25264474)

105. Koo, I.; Yao, S.; Zhang, X.; Kim, S. Comparative analysis of false discovery rate in constructing metabolic association networks. J. Bioinformatics Computational Biology 2014, 12(4), 1450018. (PMID: 25152043)

104. Koo. I.; Wei, X.; Shi, X.; Zhou, Z.; Kim, S.; Zhang, X. Constructing metabolic association networks using high-dimensional mass spectrometry data. Chemometri. Intell. Lab. 2014, 138, 193-202. (PMID: 25414536)

103. Sun, Q.; Li, Q.; Zhong, W.; Zhang, J.; Yin, X.; Sun, X.; Tan, X.; Sun, X.; Zhang, X.; Zhou, X. Dysregulation of hepatic zinc transporters in a mouse model of alcoholic liver disease. Am. J. Physiol. –Gastr. L. 2014, 307(3), 313-322. (PMID: 24924749)

102. Li., X.; Li, Y.; States, V. A.; Li, S.; Zhang, X.; Martin, R.C. The effect of black raspberry extracts on MnSOD activity in protection against Concanavalin A induced liver injury. Nutri. Cancer 2014, 9:1-8. (PMID: 24911141)

101. Koo, I.; Shi, X.; Kim, S.; Zhang, X. iMatch2: compound identification using retention index for analysis of GC-MS data. J. Chromatogr. A 2014, 1337, 202-210. (PMID: 24630063)

100. Li, Y.; Shi, X.; Zhang, J.; Zhang, X.; Martin, R. Hepatic protection and anticancer activity of curcuma: A potential chemopreventive strategy against hepatocellular carcinoma. Int. J. Oncol. 2014, 44, 505-513. (PMID: 24270742)

099. Koo, I.; Wei, X.; Zhang, X. Analysis of metabolic profiling data acquired on GC-MS, Methods in Enzymology, Vol 543: Cell-wide metabolic alterations associated with malignancy, Edited by Lorenzo Galluzzi and Guido Kramer, UK Burlington: Academic Press, 2014, pp. 315-324. (PMID: 24924140) [Book Chapter]

098. Shi, X.; Yin, X.; Zhang, X. Analysis of mouse liver metabolites on GC×GC-TOF MS. Mass Spectrometry Methods in Metabolomics, Edited by Daniel Raftery, 2014, pp. 99-105. [Book Chapter]

2013

097. Wei, X.; Shi, X.; Koo, I.; Kim, S.; Schmidt, R. H.; Arteel, G. E.; Watson, W. H.; McClain, C. J.; Zhang, X. MetPP: A computational platform for comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry-based metabolomics. Bioinformatics 2013, 29, 1786-1792. (PMID: 23665844)

096. Koo, I.; Kim, S.; Zhang, X. Comparative analysis of mass spectral matching-based compound identification in gas chromatography mass spectrometry. J. Chromatogr. A 2013, 1298, 132-138. (PMID: 23726352)

095. Wei, X.; Shi, X.; Merrick, M.; Willis, P.; Alonso, D.; Zhang, X. A method of aligning peak lists generated by gas chromatography high-resolution mass spectrometry. Analyst 2013, 138, 5453-5460. (PMID: 23885350)

094. Laulhé, S.; Geers, T. E.; Shi, X.; Zhang, X.; Nantz, M.H. Electron ionization–induced release of coded isotopic reporter ions in an m/z zone of minimal interference for quantifiable, multiplexed GC-MS analyses. Analytical Methods 2013, 5 (18), 4701 - 4706. (PMID: 24235976)

093. Phillips, M.; Cataneo, R.N.; Chaturvedi, A.; Kaplan, P.D.; Libardoni, M.; Mundada, M.; Patel, U.; Zhang, X. Detection of an extended human volatome with comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry. PloS ONE 2013, 8(9):e75274. (PMID: 24086492)

092. Kim, S.; Zhang, X. Comparative analysis of mass spectral similarity measures on peak alignment for two-dimensional gas chromatography mass spectrometry. Computational and Mathematical Methods in Medicine 2013, 509761. (PMID: 24151524)

091. Schmidt, R. H.; Jokinen, J.D.; Massey, V. L.; Falkner, K.C.; Shi, X.; Yin, X.; Zhang, X.; Beier, J. I.; Arteel, G. E. Olanzapine activates hepatic mammalian target of rapamycin (mTOR): new mechanistic insight into metabolic dysregulation with a typical antipsychotic drugs. J. Pharmacol. Exp. Ther. 2013, 347, 126-135. (PMID: 23926289)

090. Phillips, M.; Byrnes, R.; Cataneo, R.N.; Chaturvedi, A.; Kaplan, P.; Libardoni, M.; Mehta, V.; Mundada, M.; Patel, U.; Ramakrishna, N.; Schiff, P.; Zhang, X. Detection of volatile biomarkers of therapeutic radiation in breath. J. Breath Res. 2013, 7:036002. (PMID: 23793046)

089. Song, M.; Schuschke, D. A.; Zhou, Z.; Chen, T.; Shi, X.; Zhang, J.; Zhang, X.; Pierce, W.M.; Johnson, T.W.; Vos, M. B.; McClain, C. J. Modest fructose beverage intake causes liver injury and fat accumulation in marginal copper deficient rats. Obesity 2013, 21(8), 1669-1675. (PMID: 23512597)

088. Wei, X.; Shi, X.; Tang, Y.; Sun, W.; Yin, X.; Sun, X.; Bogdanov, B.; Kim, S.; McClain, C. J.; Zhou, Z.; Zhang, X. Chronic alcohol exposure disturbs lipid homeostasis at the adipose-liver axis: analysis of triacylglycerols using high-resolution mass spectrometry in combination with in vivo metabolite deuterium labeling. PloS ONE 2013, 8(2):e55382. (PMID: 23405143)

087. Jeong, J.; Zhang, X.; Shi, X.; Kim, S.; Shen, C. An efficient post-hoc integration method improving peak alignment of metabolomics data from GC×GC/TOF-MS. BMC Bioinformatics 2013, 14:123. (PMID: 23575005)

2012

086. Wei, X.; Shi, X.; Kim, S. H.; Zhang, L.; Patrick, J. S.; Binkley, J.; McClain, C. J.; Zhang, X. Data preprocessing method for liquid chromatography mass spectrometry-based metabolomics. Anal. Chem. 2012, 84, 7963–7971. (PMID: 22931487)

085. Kim, S.; Koo, I.; Jeong, J.; Wu, S.; Shi, X.; Zhang, X. Compound identification using partial and semi-partial correlations for gas chromatography mass spectrometry data. Anal. Chem. 2012, 84, 6477–6487. (PMID: 22794294)

084. Kim, S.; Koo, I.; Wei, X.; Zhang, X. A method of finding optimal Weight factors for compound identification in gas chromatography–mass spectrometry. Bioinformatics 2012, 28(8), 1158–1163. (PMID: 22333245)

083. Shi, X.; Wahlang, B.; Wei, X.; Yin, X.; Falkner, K.; Prough, R.; Kim, S.; McClain, C. J.; Cave, M.; Zhang, X. Metabolomic analysis of the effects of polychlorinated biphenyls in non-alcoholic fatty liver disease. J. Proteome Res. 2012, 11, 3805–3815. (PMID: 22686559)

082. Zhong, W.; Zhao, Y.; Sun, X.; Wei, X.; Shi, X.; Sun, W.; Yin, X.; Sun, X.; Kim, S.; McClain, C. J.; Zhang, X.; Zhou, Z. Chronic alcohol exposure stimulates adipose tissue lipolysis in mice: Role of reverse triglyceride transport in the pathogenesis of alcoholic steatosis. Am. J. Pathol. 2012, 180, 998–1007. (PMID: 22234172)

081. Zhang, C.; Lu, X.; Tan, Y.; Li, B.; Miao, X.; Jin, L.; Shi, X.; Zhang, X.; Miao, L.; Li, X.; Cai, L. Diabetes-induced hepatic pathogenic damage, inflammation, oxidative stress, and insulin resistance was exacerbated in zinc deficient mouse model. PloS ONE 2012, 7(12):e49257. (PMID: 23251339)

080. Koo, I.; Zhao, Y.; Zhang, J.; Kim, S.; Zhang, X. A method of calculating the second dimension hold-up time for comprehensive two-dimensional gas chromatography. J. Chromatogr. A 2012, 1260, 193–199. (PMID: 22964052)

079. Zhang, J.; Koo, I.; Wang, B.; Gao, Q.; Zheng, C.; Zhang, X. A large scale test dataset to determine optimal retention index threshold based on three mass spectral similarity measures. J. Chromatogr. A 2012, 1251, 188–193. (PMID: 22771253)

078. Laulhe, S.; Bogdanov, B.; Johannes, L. M.; Gutierrez, O.; Harrison, J.G.; Tantillo, D.J.; Zhang, X.; Nantz, M.H. Fragmentation of oxime and silyl oxime ether odd-electron positive ions by the McLafferty rearrangement: new insights on structural factors that promote α,β-fragmentation. J. Mass Spectrom. 2012, 47(6), 676–686. (PMID: 22678949)

077. Jeong, J.; Shi, X.; Zhang, X.; Kim, S.; Shen, C. Model-based peak alignment of metabolomics profiling from comprehensive two-dimensional gas chromatography mass spectrometry. BMC Bioinformatics 2012, 13:27. (PMID: 22316124)

076. Feutz, M. M.; Riley, P.C.; Zhang, X.; Adamec, J.; Thompson, C.; Couetil, L.L. Proteomic analysis of bronchoalveolar lavage fluid in an equine model of asthma during a natural antigen exposure trial. J. Integrated Omics 2012, 2, 123-131.

075. Kim, S.; Ouyang, M.; Zhang, X. Compute Spearman correlation coefficient with Matlab/CUDA. IEEE International Symposium on Signal Processing and Information Technology, Dec. 12-15, 2012. Ho Chi Minh City, Vietnam. [Conference paper]

074. Koo, I.; Zhang, X.; Kim, S. Reconstruction of metabolic association networks using high-throughput mass spectrometry data. 2012 International Conference on Intelligent Computing, July 25-29, 2012. Huangsan, Hunan, China. [Conference paper]

073. Wei, X.; Shi, X.; Kim, S.; McClain, C. J.; Zhang, X. A novel two-stage alignment method for liquid chromatography mass spectrometry-based metabolomics. 2012 International Conference on Intelligent Computing, July 25-29, 2012. Huangsan, Hunan, China. [Conference paper]

2011

072. Wei, X.; Sun, W.; Shi, X.; Koo, I.; Wang, B.; Yin, X.; Tang, Y.; Bogdanov, B.; Kim, S.; Zhou, Z., McClain, C. J.; Zhang, X. MetSign: A computational platform for high-resolution mass spectrometry-based metabolomics. Anal. Chem. 2011, 83, 7668–7675. (PMID: 21932828)

071. Koo, I.; Zhang, X.; Kim, S. Wavelet- and Fourier-Transforms-based spectrum similarity approaches to compound identification in gas chromatography/mass spectrometry. Anal. Chem. 2011, 83, 5631–5638. (PMID: 21651237)

070. Kim, S.; Fang, A.; Wang, B.; Jeong, J.; Zhang, X. An optimal peak alignment for comprehensive two-dimensional gas chromatography mass spectrometry using mixture similarity measure. Bioinformatics 2011, 27, 1660–1666. (PMID: 21493650)

069. Zhang, J.; Fang, A.; Wang, B.; Bogdanov, B.; Kim, S. H.; Zhou, Z.; McClain, C. J.; Zhang, X. iMatch, A retention index tool for analysis of gas chromatography mass spectrometry data. J. Chromatogr. A 2011, 1218, 6522–6530. (PMID: 21813131)

068. Zhao, Y.; Zhang, J.; Wang, B.; Kim, S.; Fang, A.; Bogdanov, B.; Zhou, Z.; McClain, C. J.; Zhang, X. A method of calculating the second dimension retention index in comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry. J. Chromatogr. A 2011, 1218, 2577–2583. (PMID: 21429495)

067. Jeong, J.; Shi, X.; Zhang, X; Kim, S.; Shen, C. An empirical Bayes model using a competition score for metabolite identification in gas chromatography mass spectrometry. BMC Bioinformatics 2011, 12:392. (PMID: 21985394)

066. Kim, S.; Koo, I.; Fang, A.; Zhang, X. Smith-Waterman peak alignment for comprehensive two-dimensional gas chromatography mass spectrometry. BMC Bioinformatics 2011, 12:235. (PMID: 21676240)

065. Riley, C. P.; Zhang, X.; Nakshatri, H.; Schneider, B.; Regnier, F. E.; Adamec, J.; Buck, C. A large, consistent plasma proteomics data set from prospectively collected breast cancer patient and healthy volunteer samples. J. Transl. Med. 2011, 9:80. (PMID: 21619653)

064. Zhao, Y.; Tan, Y.; Dai, J.; Li, B.; Guo, L.; Cui, J.; Wang, G.; Shi, X.; Zhang, X.; Mellen, N.; Li, W.; Cai, L. Exacerbation of diabetes-induced testicular apoptosis by zinc deficiency is most likely associated with oxidative stress; p38 MAPK activation; and p53 activation in mice. Toxicol. Lett. 2011, 200, 100–106. (PMID: 21078376)

063. Wang, B.; Fang, A.; Shi, X.; Kim, S.; Zhang, X. A comprehensive peak alignment algorithm for two-dimensional gas chromatography time-of-flight mass spectrometry. 2011 International Conference on Intelligent Computing, Aug 11-14, 2011. Zhengzhou, Henan, China. [Conference paper]

062. Koo, I.; Zhang, X.; Kim, S. Comparison of spectral similarity measures for compound identification. The 5th International Conference on Bioinformatics and Biomedical Engineering, May 10-12, 2011. Wuhan, Hubei, China. [Conference paper]

061. Chen, Y.T.; Zhang, J.; Zhang, X.; Kim, S. Statistical analysis of gas chromatography retention index database. The 5th International Conference Bioinformatics and Biomedical Engineering, May 10-12, 2011. Wuhan, Hubei, China. [Conference paper]

060. Zhang, X. Review on the book “Proteome Bioinformatics” (ISBN 978-1-60761-443-2). Briefings in Bioinformatics 2011, 12, 80-81.

2010

059. Wang, B.; Fang, A.; Heim, J.; Bogdanov, B.; Pugh, S.; Libardoni, M.; Zhang, X. DISCO: distance and spectrum correlation optimization alignment for two dimensional gas chromatography time-of-flight mass spectrometry - based metabolomics. Anal. Chem. 2010, 82, 5069–5081. (PMID: 20476746)

058. Wang, B.; Valentine, S.; Plasencia, M.; Raghuraman, S.; Zhang, X. Artificial neural networks for the prediction of peptide drift time in ion mobility mass spectrometry. BMC Bioinformatics 2010, 11:182. (PMID: 20380738)

057. Zhang, X.; Fang, A.; Riley, C. P.; Wang, M.; Regnier, F. E. Buck, C. Multi-dimensional liquid chromatography in quantitative proteomics. Anal. Chimica Acta 2010, 664, 101–113. (PMID: 20363391)

056. Riley, P.C.; Gough, S.E.; He, J.; Jandhyala, S. S.; Kennedy, B.; Orcun, S.; Ouzzani, M.; Buck, C.; Roumani, A.M.; Zhang, X. The Proteome Discovery Pipeline – A data analysis pipeline for mass spectrometry-based differential proteomics discovery. The Open Proteomics Journal 2010, 3, 8–19.

055. Wang, B.; Valentine, S.; Plasencia, M.; Zhang, X. Prediction of drift time in ion mobility-mass spectrometry based on peptide molecular Weight. Protein Pept. Lett. 2010, 17(9), 1143–1147. (PMID: 20509855)

054. Wang, B.; Chen, P.; Zhang, J.; Zhao G.; Zhang, X. Inferring protein-protein interactions using a hybrid GA/SVM method. Protein Pept. Lett. 2010, 17(9), 1079–1084. (PMID: 20509854)

053. Wang, B.; Chen, P.; Wang, P.; Zhao, G.; Zhang, X. Radial basis function neural network ensemble for predicting protein-protein interaction sites in heterocomplexes. Protein Pept. Lett. 2010, 17(9), 1111–1116. (PMID: 20509853).

052. Wang, B.; Zhang, X. Evolutionary computation applications in current bioinformatics. New Achievement in Evolutionary Computation Edited by Peter Korosec, 2010, 173–180. [Book Chapter]

051. Zhang, J.; Wang, B.; Zhang, X. Optimal selection of support vector regression parameters and molecular descriptors for retention indices prediction. Advanced Intelligent Computing Theories and Applications with Aspects of Artificial Intelligence. Aug. 18–21, 2010, Changsha, Hunan, China. [Conference paper]

050. Wang, B.; Zhang, J.; Zhang, X. Multiple linear regression for peptides drift time prediction. The 2010 International Conference on Bioinformatics, Computational Biology, Genomics and Chemoinformatics, July 12–14, 2010. Orlando, FL. [Conference paper]

2009

049. Zhang, X.; Oh, C.; Riley, C. P.; Buck, C.; Cho, H. Computational approaches to peptide retention time prediction for proteomics. Biological Data Mining Edited by Jake Y. Chen, Stefano Lonardi, 2009, 337–349. [Book Chapter]

2008

048. Zhang, X.; Orcun S.; Ouzzani, M.; Oh, C. Mass informatics in differential proteomics. Encyclopedia of Data Warehousing and Mining - 2^nd Edition, Edited by John Wang, 2008, 1176–1181. [Book Chapter]

047. Oh, C.; Huang, X.; Buck, C.; Regnier, E. F.; Zhang, X. Comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry peak sorting algorithm. J. Chromatogr. A 2008, 1179, 205–215. (PMID: 18093607)

046. Zhang, M.; Ouyang, Q.; Stephenson, A.; Kane, M.D.; Salt, D. E.; Prabhakar, S.; Burger, J.; Buck, C.; Zhang, X. Interactive analysis of ‘omics molecular expression data. BMC Systems Biology 2008, 2:23. (PMID: 18312669)

045. Shen, C.; Wang, Z.; Shankar, G.; Zhang, X.; Li, L. A hierarchical statistical model to assess the confidence of peptide and protein identifications made by tandem mass spectrometry. Bioinformatics 2008, 24, 202–208. (PMID: 18024968)

044. Saha, S.; Harrison, S.H.; Shen, C.; Tang, H.; Radivojac, P.; Arnold, R. J.; Zhang, X.; Chen, J.Y. HIP2: an online database of human plasma proteins from healthy individuals. BMC Medical Genomics 2008, 1:12. (PMID: 18439290)

043. Culbertson, A.W.; Williams, W.B.; Mckee, A. G.; Zhang, X.; March, K.L.; Naylor, S.; Valentine, S.J. Inside the personalized medicine toolbox: GC×GC-mass spectrometry for high throughput profiling of the human plasma metabolome. LC/GC 2008, 26(6), 560–569.

042. Ralston-Hooper, K.; Baker, S.; Hopf, A.; Oh, C.; Zhang, X.; Adamec, J.; Sepúlveda, M.S. Development of GC-GC/TOF-MS metabolomics for use in ecotoxicological studies with invertebrates. Aquatic Toxicology 2008, 88, 48–52. (PMID: 18423646)

2007

041. Oh, C.; Zak, S.H.; Mirzaei, H.; Regnier, F. E.; Zhang, X. Neural network prediction of peptide behavior in strong anion exchange chromatography. Bioinformatics 2007, 23, 114–118. (PMID: 17092987)

040. Zhang, X.; Oh, C.; Riley, C. P.; Buck, C. Current status of computational approaches for protein identification using tandem mass spectra. Current Proteomics 2007, 4, 121–130.

039. Zhao, Y.; Fleet, C. J, Adamec, J.; Terry, D. E.; Zhang, X.; Kemeh, S.; Davisson, J. V.; Weaver, M. C. Effects of hindlimb unloading and bisphosphonates on the serum proteome of rats. Bone 2007, 41, 646–658. (PMID: 17627911)

038. Qiu, R.; Zhang, X.; Regnier, F. E. A method for the identification of glycoproteins from human serum by a combination of lectin affinity chromatography along with anion exchange and Cu-IMAC selection of tryptic peptides. J. Chromatogr. B 2007, 845, 143–150. (PMID: 16945596)

037. Fedulova, I.; Ouyang, Z.; Buck, C.; Zhang, X. PepTiger: search engine for error-tolerant protein identification from de novo sequence tags. The Open Spectroscopy Journal 2007, 1, 1–8.

036. Zhang, M.; Zhang, X.; Zhang, X.; Prabhakar, S. Tracing lineage beyond relational operators. VLDB’07 Proceedings of the 33^rd International Conference on Very Large Databases 2007, 1116–1127. [Conference paper]

2006

035. Pevtsov, S.; Fedulova, I.; Mirzaei, H.; Buck, C.; Zhang, X. Performance evaluation of existing de novo sequencing algorithms. J. Proteome Res. 2006, 5, 3018–3028. (PMID: 17081053)

034. Asara, J. M.; Zhang, X.; Zheng, B.; Christofk, H.H.; Wu, N.; Cantley, L.C. In-gel stable isotope labeling: a strategy for mass spectrometry based relative quantification. J. Proteome Res. 2006, 5, 155–163. (PMID: 16396506)

033. Asara, J. M.; Zhang, X.; Zheng, B.; Christofk, H.H.; Wu, N.; Cantley, L.C. In-gel stable isotope labeling for relative quantification using mass spectrometry. Nature Protocols 2006, 1, 46–51. (PMID: 17406210)

2005

032. Zhang, X.; Asara, J. M.; Adamec, J.; Ouzzani, M.; Elmagarmid, A. K. Data preprocessing in liquid chromatography mass spectrometry based proteomics. Bioinformatics 2005, 21, 4054–4059. (PMID: 16150809)

031. Zhang, X.; Hines, W.; Adamec, J.; Asara, J.; Naylor, S.; Regnier, F. E. An automated method for the analysis of stable isotope labeling data for proteomics. J. Am. Soc. Mass Spectrom. 2005, 16, 1181–1191. (PMID: 15922621)

030. Ouzzani, M.; Aref, W.G.; Bertino, E.; Christine, A.C.; Clifton, C. W.; Hon, W.; Elmagarmid, A. K.; Ghafoor, A.; Hambrusch, S.E.; Prabhakar, S.; Vitter, J.; Zhang, X. The Indiana Center for Database Systems at Purdue University. SIGMOD Record 2005, 34, 53–58.

2004

029. Davidov, E.; Clish, C. B.; Oresic, M.; Meys, M.; Stochaj, W.; Snell, P.; Lavine, G.; Londo, T. R.; Adourian, A.; Zhang, X.; Johnston, M.; Morel, N.; Marple, E.W.; Plasterer, T. N.; Neumann, E.; Verheij, E.; Vogels, J, T.W.E.; Havekes, L. M.; Greef, J.; Naylor, S. Methods for the differential integrative omics analysis of plasma from a transgenic disease animal model. Omics: A Journal of Integrative Biology 2004, 8, 267–288. (PMID: 15703476)

028. Clish, C. B.; Davidov, E.; Oresic, M.; Plasterer, T.; Lavine, G.; Londo, T. R.; Meys, M.; Snell, P.; Stochaj, W.; Adourian, A.; Zhang, X.; Morel, N.; Neumann, E.; Verheij, E.; Vogels, J, T.W.E.; Havekes, L. M.; Afeyan, N.; Regnier, F. E.; Greef, J.; Naylor, S. Integrative biological analysis of the APOE*3 Leiden transgenic mouse. Omics: A Journal of Integrative Biology 2004, 8, 3–13. (PMID: 15107233)

2002

027. Wang, S.; Zhang, X.; Regnier, F. E. Quantitative proteomics strategy involving the selection of peptides containing both cysteine and histidine from tryptic digests of cell lysates. J. Chromatogr. A 2002, 949, 153–162. (PMID: 11999731)

2001

026. He, B.; Burke, J.; B.; Zhang, X.; Zhang, R.; Regnier, F. E. A picoliter volume mixer for microfluidic analytical systems. Anal. Chem. 2001, 73, 1942–1947. (PMID: 11354474)

025. Geng, M.; Zhang, X.; Bina, M.; Regnier, F. E. Proteomics of glycoproteins based on affinity selection of glycopeptides from tryptic digests. J. Chromatogr. B 2001, 752, 293–306. (PMID: 11270868)

024. Regnier, F. E.; Amini, A.; Chakraborty, A.; Geng, M.; Ji, J.; Riggs, L.; Sioma, C.; Wang, S.; Zhang, X. Multidimensional chromatography and the signature peptide approach to proteomics. LC/GC 2001, 19, 200–213.

023. Wang, X.; Tian, J.; Yin, X.; Zhang, X.; Qin, Z.; Li, Z.; Wang, Q.; Li, S. Distribution of trace elements in normal and tumor-bearing mice using the multitracer technique. Biological Trace Element Research 2001, 81, 177–183. (PMID: 11554398)

2000

022. Zhang, X.; Regnier, F. E. Analysis of channel effects on separation efficiency in rectangularcapillary electrochromatography columns. J. Chromatogr. A 2000, 869, 319–328. (PMID: 10720247)

021. Ji, J.; Chakraborty, A.; Geng M.; Zhang, X.; Amini, A.; Bina, M.; Regnier, F. E. Strategy for qualitative and quantitative analysis in proteomics based on signature peptides. J. Chromatogr. B 2000, 745, 197–210. (PMID: 10997715)

020. Wang, X.; Tian, J.; Yin, X.; Zhang, X.; Wang, Q. The excretion of biotrace elements using the multitracer technique in tumor-bearing mice. Applied Radiation and Isotopes 2000, 53, 969–974. (PMID: 11077959)

019. Li, W.; Yin, X.; Zhang, X.; Sun, T.; Qin, Z.; Ambe, S.; Ohkubo, Y.; Ambe, F. Projectile-mass dependence of the linear momentum transfer in central collisions. J. Radioanal. Nucl. Chem. 2000, 243, 797–801.

Before 2000

018. Wang, X.; Yin, X.; Zhang, X.; Li, Z.; Tian J.; Wu, M.; Sheng, X. Excretion of biotrace elements using the multitracer technique in mice. J. Radioanal. Nucl. Chem. 1999, 240, 963–967.

017. Yin, X.; Wang, X.; Zhang, X.; Li, W.; Tao, Z.; Du, J. Preparation of a radioactive multitracer solution from the reaction of selenium with 25 Mev/nucleon ⁴⁰Ar ions. J. Radioanal. Nucl. Chem. 1997, 221, 225–226.

016. Yin, X.; Zhang, X.; Sun, T.; Qin, Z.; Zhao, L. Preparation of multitracer from the interaction of selenium with 25 MeV/A ⁴⁰Ar ions. J. Nucl. Tech. 1997, 20, 382–384.

015. Du, J.; Yin, X.; Wang, X.; Dai, X.; Zhang, X.; Sun, T.; Tao, Z. Adsorption study of 47 elements on alumine and bentonite using a multitracer technique. Adsorption Science and Technology 1997, 15, 341–347.

014. Sun, T.; Li, W.; Wu, D.; Yin, X.; Zhao, L.; Zhang, X.; Qin, Z.; Zheng, J.; Liu, G.; Jing, G. Target residues from interaction of ¹⁹⁷Au with 8~24 MeV/nucleon ⁴⁰Ar ions. J. Nucl. Radiochem. 1997, 19, 49–54.

013. Zhang, X.; Yin, X.; Li, W.; Sun T.; Qin, Z.; Zhao L.; Wu D. Production of hafnium nuclides in the reactions of 6.3~24.5 MeV/nucleon ⁴⁰Ar ions with nature tungsten. Radiochem. Acta 1996, 75, 7–10.

012. Yin, X.; Du, J.; Zhang, X.; Wang, X.; Dai, X.; Sun, T.; Tao, Z. Preparation of multitracer nuclides from UO₂(NO₃)₂ irradiated by ⁴⁰Ar ion beam. J. Radioanal. Nucl. Chem. 1996, 214, 89–94.

011. Qin, Z.; Li, W.; Yin, X.; Zhang, X. , Sun, T.; Zhao, L.; Wang, X. Multitracer technique and prospects of its application. TREND in Nucl. Phys. 1996, 13, 31–34.

010. Zhang, X.; Li, W.; Sun, T.; Yin, X.; Qin, Z.; Zhao, L.; Wu, D.; Zheng, J.; Liu, G. Production of hafnium isotopes from interaction of ^natW with 6.3~24.6 MeV/u ⁴⁰Ar ions. J. High Energy Phys. Nucl. Phys. 1996, 20, 21–25.

009. Qin, Z.; Li, W.; Sun, T.; Zhao, L.; Zhang, X.; Yin, X.; Wu, D.; Zhen, J.; Liu, G.; Zhao, Z. Target residues from the interaction of natural uranium target with 20 MeV/nucleon ⁴⁰Ar ions. J. Nucl. Radiochem, 1996, 18, 229–233.

008. Li, W.; Sun, T.; Wu, D.; Sun, R.; Zhao, L.; Yin, X.; Zhang, X.; Luo, Q.; Zhang, F.; Jin, G. Target residues from the interaction of copper with 20~46 MeV/nucleon ¹²C ions. Radiochim. Acta 1996, 72, 109–119.

007. Liu, G.; Cheng, K.; Yu, X.; Zheng, J.; Jin, W.; Sun T.; Wu, D.; Zhao, L.; Zhang, X.; Yin, X.; Qin, Z. Fragment angular distributions for ⁴⁰Ar + ¹⁹⁷Au reaction. Chin. J. Nucl. Phys. 1995, 17, 21–23.

006. Zhang, X.; Li, W.; Yin, X.; Wen, W.; Sun, T.; Jin, G.; Luo, Q. Mass yield distribution in intermediate energy heavy ion reactions. Chinese J. Nucl. Phys. 1995, 17, 247–249.

005. Zhang, X.; Li, W.; Yin, X.; Sun, T.; Ambe, S.; Ohkubo, Y.; Iwamoto, M.; Kobyashi, Y.; Maeda, H.; Ambe, F. Isotopic distributions of Hf from the interaction of heavy ions with W. J. Nucl. Radiochem. 1995, 17, 193–197.

004. Yang, W.; Yuan, S.; Mou, W.; Zhang, X.; Li, Z.; Yu, X.; Gan, Z.; Liu, H.; Guo, Y.; Zhang, J.; Lei, X.; Guo, J.; Du, Y.; Zhao, L.; Zhang, X. A new heavy neutron-rich isotope ²³⁹Pa. J. High Energy Phys. Nucl. Phys. 1995, 19, 479–480.

003. Zhang, X.; Yin, X.; Li, W.; Qin, Z.; Zhao, L.; Wu, D.; Sun, T. Study on the adsorption behavior of fission products on mud and sand in Yellow River using multitracer. J. Nucl. Radiochem. 1995, 17, 60–64.

002. Yin, X.; Li, W.; Zhang, X.; Sun, T.; Ambe, S.; Ohkubo, Y.; Iwamoto, M.; Kobyashi, Y.; Maeda, H.; Ambe, F. Target residues from the interaction of copper with 40 MeV/u ⁴⁰Ar ions. J. High Energy Phys. Nucl. Phys. 1995, 19, 991–997.

001. Liu, G.; Cheng, K.; Yu, X.; Zheng, J.; Jin, W.; Sun T.; Wu, D.; Zhao, L.; Zhang, X.; Yin, X.; Qin, Z. Fragment angular distributions of the 600 Mev ⁴⁰Ar + ¹⁹⁷Au reaction. J. High Energy Phys. Nucl. Phys. 1995, 19, 305–309.

Dr. Xiang Zhang Lab