About
NIGMS-LCTRC Presidential Research Scholar
Assistant Professor of Medicine
Department of Medicine
Division of Gastroenterology, Hepatology, and Nutrition
Dr. Ekuban's research focuses on elucidating the molecular mechanisms by which environmental pollutants, particularly per- and polyfluoroalkyl substances (PFAS), interact with lifestyle factors such as alcohol consumption to influence liver disease progression. Using integrative approaches that combine mechanistic toxicology, genomics, and translational models, his work aims to uncover how these exposures contribute to the pathogenesis of liver disease and to identify potential targets for intervention. His long-term goal is to develop evidence-based interventions and biomarkers for environmental health protection, bridging fundamental toxicological research with clinical applications.
Research Keywords: PFAS, Environmental Liver Disease, Nuclear receptor signaling, Alcohol-associated liver disease, Mechanistic toxicology