Brendan Depue, Ph.D., Department of Psychological and Brain Sciences, University of Louisville

"Neural Correlates Involved in Down Regulating Negative Memory and Emotion"

Self-regulation is arguably one of the key behavioral outcomes from the evolutionary adaptation of an enlarged cerebral cortex, which enables humans to manipulate their own behavior and environment. Its depletion is manifest in every psychiatric and neurological disorder in some context, indicating its transdiagnostic nature. Our lab has continued investigating a variety of aspects of self-regulation in psychiatric and neurological non-diagnostic and diagnostic samples. The current talk will focus on the results of these current investigations, which focuses on combining structure, function and the connectivity of both to explain behavioral or clinical variability.

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