James Graham Brown Cancer Center BCC Directed Gift Pilot Project Program

~ Request For Proposals ~

There are more than 15,000 living donors to the UofL James Graham Brown Cancer Center. Thousands of people have given to specifically advance the research efforts of the JGBCC – more than half of all giving to the JGBCC has been directed to cancer research.  The donor intent for most of these donations is simply to advance cancer research and support the scientists who are working for better understandings and treatments.  This includes basic, translational and clinical research efforts, and spans numerous cancer types and stages.

The James Graham Brown Cancer Center (JGBCC) has, as one of its major objectives, the funding of early stage research projects aimed at new cancer biology, identification of drugs and targets, and development of novel pre-clinical agents or diagnostics. The emphasis for Cycle 1 was on generation of new data in translational studies in cancer with a high potential for future funding. It is expected that these pilot projects will lead to competitive federal grant funding applications.

Applicants must be faculty members at the University of Louisville or an affiliated institution (e.g., the Louisville VA) and active members of the JGBCC at the time of application. Applicants may include junior faculty, established faculty who are initiating new research efforts in cancer, new collaborative projects between laboratory and clinical investigators, or new collaborations between investigative groups within the JGBCC and UofL.  Existing grant support is not a deterrent for funding, but simultaneous funding for the same project is not allowed.

Pilot Projects will be awarded for one-year, with a total budget of up to $25,000 or $50,000 depending on the Directed Gift.  Grants will be awarded through the JGBCC; thus, no overhead will be charged and a proposal clearance form is not required. Applicants are strongly encouraged to apply for funds that meet the specific need, not the maximum in each category unless fully justified. The emphasis for these pilot grants is the generation of new data, not funding for general laboratory support.

The directed Gifts are in the following areas with the Pilot Project application amounts:

  • Breast Cancer - $25,000.
  • Leukemia - $25,000 and some limited to $50,000.
  • Lung Cancer - $25,000 and some limited to $50,000.
  • Melanoma - $25,000 and some limited to $50,000.
  • Prostate Cancer - $25,000.

 Please note: there are multiple Pilot Projects available for Breast Cancer, Lung Cancer, Leukemia, and Melanoma.
1% P.I. salary is allowed.
These Pilot Projects are for highly focused proposals with specific milestones.

Requirements:

Application(Margins:  0.5” all around; and 11 pt. font as per NIH guidelines)
Research Description:
      Lay Abstract, Significance, and Impact:  Limit 1 page combined.
      Scientific Abstract, Research Plan, Milestones, and Budget:  Limit 2 pages combined.
      NIH Biosketch.

Post award:  Scientific and Donor Report.
Results and Milestones from funded work:
      Lay Abstract, Scientific Abstract, Significance, Impact, and Results/Milestones:  Limit 4 pages combined.

The Scientific and Donor Reportwill be sent to the Donor.  The awardee will have a meeting and presentation with the Donor if so requested.


Proposals are due by close-of-business on the date given in the RFP, as ONE PDF to

Proposals will be reviewed and Pilot Project Grants for this cycle of funding will be awarded within 6 weeks.

Upon funding, recipients will receive an account from the JGBCC fiscal office, which will administer the grant.  Use of these funds is restricted to support of research activities, including faculty and technical support, supplies, animal costs, and minor equipment (<$1,000).  Funds will NOT support student tuition & fees, travel or publications.

In all instances, regulatory approvals (e.g., IRB, IACUC, IBC) are the responsibility of the applicant.  No pilot grant will be funded unless and until all valid, applicable approval letters have been submitted to the Directed Gift Administrator, Diane Konzen.