Sandra S. Wise, Ph.D.

Assistant Professor

Department of Pharmacology and Toxicology


Research Tower A 1407 sandra.wise@louisville.edu 502–852–5163

Education

Ph.D. in Molecular Biology and Biochemistry, University of Maine (2013)

Research Areas and Projects

Dr. Wise’s research interests include how environmental chemicals, such as hexavalent chromium, depleted uranium and oil and dispersed oil products, can transform normal cells into cancer cells. These studies have focused on DNA repair deficiency and its impact on chromosome instability as a driving mechanism to cellular transformation and the development of disease. Currently,  she is pursuing how cells exposed to these chemicals induce DNA and chromosomal damage yet are able to survive and evade the normal cell death pathways that should occur in order to protect the organism from disease.