Nobuyuki Matoba, Ph.D.


Department of Pharmacology and Toxicology

CTRB 415 270–691–5955 Faculty Site


Ph.D., Applied Life Sciences, Kyoto University, Japan (2001)

Research Areas and Projects

Dr. Matoba’s research is focused on the development of protein pharmaceuticals.  To this end, they utilize a plant-based transient protein production system. This technology enables quick transition of candidate proteins from discovery and preclinical studies to clinical testing and ultimately provides cost-effective vaccines and therapeutics for developing countries.  They employ multidisciplinary experimental methodologies including protein engineering, biochemistry, analytical chemistry, antiviral research and immunology.  Currently, one of their projects is developing a vaccine against inflammatory bowel disease and colitis-associated colon cancer.  Another project is investigating the cancer diagnostic and therapeutic potentials of a “lectibody”, an antibody-lectin chimera that can recognize a broad spectrum of cancer cells.  Our projects are funded by NIH, DoD and Helmsley Charitable Trust.