Grant Awards
Updated April 1, 2024
Those efforts require the financial means to continue toward the goal of making the world a better place through breakthroughs in research.
While certain grant funding makes headlines, all is vital in the mission to advance the knowledge of clinicians and care-givers to better treat their patients and help them live their lives to the fullest.
We congratulate the members of our department whose hard work, dedication and curiosity make it possible to move forward in those quests.
(Source: UofL Office of Research & Innovation Metrics)
February 2024
Principal Investigator
Division
Sponsor
Title
Amount
Howard Donninger, M.D.
Oncology/Hematology
KY Cabinet for Health and Family Svs
Overcoming Osteosarcoma MDSC by targeting IL-6 C4793
$500,000
Dinesh Kalra, M.D.
Cadiovascular Medicine
Medpace Inc
ISIS678354 - A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of Olezarsen (ISIS 678354) Administered Subcutaneously to Patients with Severe Hypertriglyceridemia
$121,381
Michael Merchant, Ph.D.
Nephrology/Hypertension
University of Pittsburgh/NIH
The Role of Matrix-Bound Nanovesicles in Alcohol-Related Liver Injury
$31,275
Adam Gaweda, Ph.D.
Nephrology/Hypertension
US Department of Veterans Affairs
IPA Agreement for Dr. Adam Gaweda
$111,165
Sanjay Srivastava, Ph.D.
Environmental Medicine
NIH National Institutes of Health
Vascular Toxicity of Benzene
$664,616
January 2024
Principal Investigator
Division
Sponsor
Title
Amount
Daniel Conklin, Ph.D.
Environmental Medicine
NIH National Institutes of Health
Cardiopulmonary Toxicity of Electronic Nicotine Delivery Systems
$778,558
Matthew Cave, M.D.
Gastroenterology
US Army Medical Rsch Acquisition Activit
Liver and Systemic Effects of Toxic Exposures
$1,368,092
Walter Watson, Ph.D.
Gastroenterology
US Army Medical Rsch Acquisition Activit
Liver and Systemic Effects of Toxic Exposures
$873,034
Previous Years
2023December 2023
Principal Investigator
Division
Sponsor
Title
Amount
Helen Collins, Ph.D.
Environmental Medicine
NIH National Institutes of Health
Mechanisms Contributing to Pregnancy-Induced Cardiac Remodeling
$486,191
Michael Merchant, Ph.D.
Nephrology/
Hypertension
University of Pittsburgh
Novel Biomarkers for Post Liver Transplant NASH Fibrosis
$114,042
November 2023
Principal Investigator
Division
Sponsor
Title
Amount
Bradford Hill, Ph.D.
Environmental Medicine
NIH National Institutes of Health
Role of the PEP Cycle in Cardiac Fibrosis
$2,269,628
Allan Ramirez, M.D.
Pulmonary
CareDX
SN-C-00016 - AlloSure Lung Assessment and Metagenomics Outcomes Study (ALAMO), Protocol Number SN-C-00016
$202,388.10
October 2023
Principal Investigator
Division
Sponsor
Title
Amount
Rochelle Holm, Ph.D.
Environmental Medicine
North Carolina State University/NSF
National Science Foundation International Research Experiences for Students (IRES) Track I: Filling the Gaps in WaSH Research Through Field-based Student Research Experiences in Malawi
$68,055
Chi Li, Ph.D.
Oncology/
Hematology
NIH National Institutes of Health
A Lung Cancer Vaccine Based on Exosomes of Induced Pluripotent Stem Cells
$402,401
Clara Sears, Ph.D.
Environmental Medicine
NIH National Institutes of Health
Pre- and Postnatal Chemical Mixture Exposure, Adolescent Sleep Health, and Allostatic Load
$562,367
Banrida Wahlang, Ph.D.
Gastroenterology
US Army Medical Rsch Acquisition Activit
Acute and Sub-Chronic Exposures to Dioxin and Dioxin-Like Compounds in Liver Disease: the Role of Sex and Age
$774,620
September 2023
Principal Investigator
Division
Sponsor
Title
Amount
Daniel Nguyen
Environmental Medicine
NIH National Institutes of Health
Fibroblast TAK1 Signaling in Cardiac Fibrosis
$34,484
Levi Beverly, Ph.D.
Oncology/
Hematology
US Army Medical Rsch Acquisition Activi
Beyond CuATSM: Novel Copper Complexes for Improved ALS Therapy
$928,649
Shahab Ghafghazi, M.D.
Cardiovascular Medicine
Brigham and Women's Hospital
Enhancing Evidence Generation by Linking Randomized Clinical Research Clinical Trials (RCTs) to Real World Data (RWD) - Linkage of DELIVER Trial Participants to Their Observational Data
$9,250
August 2023
Principal Investigator
Division
Sponsor
Title
Amount
Roberto Bolli, M.D.
Cardiovascular Medicine
US Army Medical Rsch Acquisition Activit
A Phase IIA, Randomized, Double-Blind, Placebo-Controlled Study of Single or Repeated Intravenous Administration of UC-MSCs in Ischemic Cardiomyopathy (CATO)
$7,987,611
July 2023
Principal Investigator
Division
Sponsor
Title
Amount
Bradford Hill, Ph.D.
Environmental Medicine
American Heart Association
Physiologic Regulation of Metabolons in the Heart
$100,000
Shahab Ghafghazi, M.D.
Cardiovascular Medicine
American Heart Association
University of Louisville Cardiology: American Heart Association's Second Century of Science Clinical FellowResearch Education Grant
$12,000
Jason Chesney, M.D., Ph.D.
Oncology/
Hematology
KY Council on Postsecondary Education
FY24 Tobacco Settlement - Cancer Research
$3,125,000
KY Council on Postsecondary Education
FY24 Cancer Research Institute Matching
$2,053,850
Abigail Stocker, M.D.
Gastroenterology
Enterra Medical Inc
RESTING -Randomized Study of Enterra Programming with Nocturnal Cycling in Gastroparetics (CLN 001-PR-00755
$90,359
June 2023
Principal Investigator
Division
Sponsor
Title
Amount
Bradford Hill, Ph.D.
Environmental Medicine
American Heart Association
Physiologic Regulation of Metabolons in the Heart
$300,000
Brian Sansbury, Ph.D.
Environmental Medicine
Mount Sinai School of Medicine/NIH
Disturbed Crosstalk between Cholesterol Homeostatus and Inflammation Resolution in NASH
$33,115
Mount Sinai School of Medicine/NIH
EHD1-mediated Inflammation and Resolution in Atherosclerosis
$33,115
NIH National Institutes of Health
Role of Splenic Pro-Resolving Mediators During Exposure
$566,366
Madhavi Rane, Ph.D.
Nephrology/
Hypertension
Degrannin Therapeutics
Development of a Neutrophil Inhibitor to Treat ARDs
$51,417
Goetz Kloecker, M.D.
Oncology/
Hematology
PPD Development Inc
DELFI-L201 - Cancer Screening Assay using DELFI; A Clinical Validation Study in Lung Protocol: DELFI-20
$51,417
Tamer Mohamed, Ph.D.
Cardiovascular Medicine
Tenaya Therapeutics
Human Heart Slices Transduced with Adeno-Associated Virus (AAV) Human Gene Therapy Molecule TN-201
$39,330
May 2023
Principal Investigator
Division
Sponsor
Title
Amount
Theodore Smith, Ph.D.
Environmental Medicine
Robert Wood Johnson Foundation
Universal Basic Neighborhood: Reframing the Way We Address Health Equity by Using the Concept of Universal Basic Neighborhood to Expose and Treat Community Level Health Issues
$547,672
Louisville Metro Government
Lead Data Visualization
$29,640
April 2023
Principal Investigator
Division
Sponsor
Title
Amount
Rochelle Holm, Ph.D.
Environmental Medicine
Eurofins Scientific
Partnership to Support Multi-Pathogen Wastewater Surveillance Pilot in Malawi
$42,245
March 2023
Principal Investigator
Division
Sponsor
Title
Amount
Thomas Abell, Ph.D.
Gastroenterology
Mayo Clinic
Participation in the GpCRC Ancillary Study 28
$28,095
February 2023
Principal Investigator
Division
Sponsor
Title
Amount
Dinesh Kalra, M.D.
Cardiovascular Medicine
Canon Medical Systems USA
Assessment of Canon PIQE Software on Cardiac Computed Tomography Angiography
$64,416
Forest Arnold, D.O.
Infectious Diseases
Merck & Co., Inc.
A Multicenter Retrospective Study of High-Risk Patients Hospitalized with Breakthrough Infections of Severe COVID-19 in Louisville, Kentucky
$78,702
January 2023
Principal Investigator
Division
Sponsor
Title
Amount
Helen Collins, Ph.D.
Environmental Medicine
NIH National Institutes of Health
Mechanisms Contributing to Pregnancy-induced Cardiac Remodeling
$2,663,511
Forest Arnold, D.O.
Infectious Diseases
KY Cabinet for Health and Family Svs
FY 23 -Pre-Exposure Prophylaxis (PrEP) Care Coordinator Memoranda of Agreement MOA C3998
$225,885
Rochelle Holm, Ph.D.
Environmental Medicine
University of Kentucky Res. Fdn.
PIPP Phase I: Advancing Environmental Surveillance for Pandemic Prediction in Remote and Resource Poor Settings
$19,952
Anju Abhynkar, M.D.
Internal Medicine
Oatly US
Assessing Dietary Patterns and Implementing Cost-Effective Interventions to Encourage a Plant-Based Diet in an Underserved Urban Population
$5,000
December 2022
Principal Investigator
Division
Sponsor
Title
Amount
Brett Rossow, M.D.
Gastroenterology
CFF Cystic Fibrosis Foundation
Developing Innovative GastroEnterology Specialty Training (DIGEST) Program
$109,791
November 2022
Principal Investigator
Division
Sponsor
Title
Amount
Shirish Barve, Ph.D.
Gastroenertology
NIH National Institutes of Health
Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention
$702,843
Ryan Doster, M.D., Ph.D.
Infectious Diseases
NIH National Institutes of Health
Defining the Impact of Zinc on Streptococcus Agalactiae Biofilm and Colonization
$156,781
October 2022
Principal Investigator
Division
Sponsor
Title
Amount
Sanjay Srivastava, Ph.D.
Environmental Medicine
NIH National Institutes of Health
Superfund-Admin Core: Environmental Exposure and Cardiometabolic Disease - Administrative Core
$2,188,987
Michael Merchant, Ph.D.
Nephrology/
Hypertension
University of Pittsburgh
Novel Biomarkers for Post Liver Transplant NASH Fibrosis
$114,042
Tamer Mohamed, Ph.D.
Cardiovascular Medicine
Merck & Co., Inc.
Model Evaluation and Evaluating the Efficacy of Acceleron Compounds in in vitro Cultured Human Heart Tissue Slices
$100,000
Theodore Smith, Ph.D.
Environmental Medicine
Louisville Metro Government
Metro Louisville Community Outreach - UDS/Envirome Contract FY2023
$15,000
Allan Ramirez, M.D.
Pulmonary
CFF Cystic Fibrosis Foundation
Outpatient Clinical Pharmacy Services: Award for a Pharmacist and Pharmacy Technician
$67,004
Levi Beverly, Ph.D.
Oncology/
Hematology
University of Kentucky Res. Fdn.
KYNETIC Subproject: Novel Copper Complexes as Cancer-Selective Therapeutics
$3,125
September 2022
Principal Investigator
Division
Sponsor
Title
Amount
Forest Arnold, D.O.
Infectious Diseases
HRSA Health Research & Services Admin
Ryan White HIV/A DS Program Part D Coordinated HIV Services and Access to Research for Women, Infants, Children, and Youth (WICY) Existing Geographic Service Areas
$545,786
Gerald Dryden, M.D.
Gastroenterology
University of Missouri
Food-Grade Bacterium as a Vehicle for Targeted Delivery of Immunotherapeutic Molecules into Colorectal Cancer
$14,679
August 2022
Principal Investigator
Division
Sponsor
Title
Amount
Sucheta Telang, M.D.
Oncology/
Hematology
US Department of Defense
Elucidating the Role of Glycolysis in the Growth and Metastasis of HER2+ Breast Cancer
$704,250
NIH National Institutes of Health
Investigating the Role of PFKFB4 in the Immune Regulation of Lung Cancer
$182,909
Xian-Liang Tang, Ph.D.
Cardiovascular Mediine
Rhode Island Hospital
Histone Deacetylase Inhibition: A Novel Approach to Cardioprotection
$46,800
July 2022
Principal Investigator
Division
Sponsor
Title
Amount
Igor Zelko, Ph.D.
Environmental Medicine
NIH National Institutes of Health
Benzene Exposure and Heart Failure
$430,375
June 2022
Principal Investigator
Division
Sponsor
Title
Amount
Irina Kirpich, Ph.D.
Gastroenterology
NIH National Institutes of Health
Role of Soluble Epoxide Hydrolase in Alcohol-Associated Liver Disease
$2,065,910
Banrida Wahlang, Ph.D.
Gastroenterology
NIH National Institutes of Health
Evaluating Mechanisms of Sex Differences in Environmentally-Induced Metabolic Diseases
$377,865
May 2022
Principal Investigator
Division
Sponsor
Title
Amount
Aruni Bhatnagar, Ph.D.
Environmental Medicine
Commonwealth of Kentucky
DOC COVID-19 Wastewater Program - Analysis
$209,176
April 2022
Principal Investigator
Division
Sponsor
Title
Amount
Alex Carll, Ph.D.
Environmental Medicine
National Institutes of Health
Systematic Identification of Cardiotoxic E-cigarette Flavorants
$3,570,934
March 2022
Principal Investigator
Division
Sponsor
Title
Amount
Steven Jones, Ph.D.
Environmental Medicine
National Institutes of Health
Extracellular Matrix Dynamics During Remodeling
$2,167,407
January 2022
Principal Investigator
Division
Sponsor
Title
Amount
Steven Jones, Ph.D.
Environmental Medicine
National American Heart Association
LouisVille Undergraduate Training Program (LV-UP)
$164,964
T. Michael Sabo, Ph.D.
Oncology/
Hematology
National Institutes of Health
Linking the Conformational Energy Landscape to Enzymatic Function Through Functional Site Distant Mutations
$1,620,883
December 2021
Principal Investigator
Division
Sponsor
Title
Amount
Theodore Smith, Ph.D.
Environmental Medicine
Louisville/Jefferson Co Metro Government
Metro Louisville Community Outreach - UL UDS/Envirome Contract
$15,000
November 2021
Principal Investigator
Division
Sponsor
Title
Amount
Ashutosh Barve, M.D., Ph.D.
Gastroenterology
Vanderbilt University/NIH
Microbiome, Metabolites, and Alcohol in HIV to Reduce CVD (META HIV CVD)
$417,184
Gastroenterology
University of Florida/NIH
Interventions to Improve Alcohol-Related Comorbidities along the Gut-Brain axis in Persons with HIV Infection
$135,075
Theodore Smith, Ph.D.
Environmental Medicine
Rockefeller Foundation
Augmenting Traditional Clinical Genomic Surveillance of SARS-CoV-2 With Wastewater Data to Provide Valuable Complementary Insights for Public Health
$500,000
October 2021
Principal Investigator
Division
Sponsor
Title
Amount
Thomas Abell, M.D.
Gastroenterology
National Institutes of Health
Definitive Evaluation of Gastric Dysrhythmia as a Disease Mechanism by a Novel Body Surface Gastric Mapping Technique
$450,020
Forest Arnold, D.O.
Infectious Diseases
Ky. Cabinet for Health & Family Services/CDC
Pre-Exposure Prophylaxis (PrEP) Care Coordinator
$225,885
Leila Gobejishvili, Ph.D.
Gastroenterology
National Institutes of Health
Phosphodiesterase 4 Mediated Pathogenic Mechanisms in Alcohol Associated Liver Disease
$1,778,856
Theodore Smith, Ph.D.
Environmental Medicine
Rockefeller Foundation
Precision Public Health Interventions Playbook: Wastewater and COVID Vaccinations
$500,000
September 2021
Principal Investigator
Division
Sponsor
Title
Amount
David Powell, Ph.D.
Nephrology/
Hypertension
National Institutes of Health
ABIN1 Dysfunction in Lupus Nephritis
$2,932,372
August 2021
Principal Investigator
Division
Sponsor
Title
Amount
Daniel Conklin, Ph.D.
Environmental Medicine
National Institutes of Health
Cardiovascular Benefits of Inhaled Biogenic Volatile Organic Compounds
$429,688
July 2021
Principal Investigator
Division
Sponsor
Title
Amount
Vivek Sharma, M.D.
Oncology/
Hematology
University of North Carolina
Public Health Surveillance for the Prevention of Complications of Bleeding Disorders
$10,000
Vatsalya Vatsalya, Ph.D.
Gastroenterology
National Institutes of Health
Lactobacillus Rhamnosus: A Novel Probiotic Therapy for Treating Alcohol Use Disorder
$703,875
June 2021
Principal Investigator
Division
Sponsor
Title
Amount
Jason Hellmann, Ph.D.
Environmental Medicine
New York University
Aspirin-triggered Specialized Pro-resolving Mediators in Increasing Weight and Atherosclerotic Cardiovascular Disease
$82,643
Craig McClain, M.D.
Gastroenterology
National Institutes of Health
The Role of Nutrition in the Development/Progression of Alcohol-Induced Organ Injury
$6,976,092
Ruth Carrico, Ph.D.
Infectious Diseases
Louisville/Jefferson Co Metro Government
Testing Capacity Expansion
$150,000
Theodore Smith, Ph.D.
Environmental Medicine
Louisville/Jefferson Co Metro Government
COVID-19 Wastewater Sampling
$155,247
May 2021
Principal Investigator
Division
Sponsor
Title
Amount
Paula Bates, Ph.D.
Oncology/
Hematology
U.S. Economic Development Administration
The Pandemic-Related Product Acceleration & Responsive Entrepreneurship (PRePARE) Program
$750,000
April 2021
Principal Investigator
Division
Sponsor
Title
Amount
Craig McClain, M.D.
Gastroenterology
National Institutes of Health
University of Louisville Hepatobiology and Toxicology COBRE
$11,356,981
March 2021
Principal Investigator
Division
Sponsor
Title
Amount
Loretta Jophlin, M.D., Ph.D.
Gastroenterology
National Institutes of Health
Interaction of the Microtubule Cytoskeleton and Perilipin-2 Regulates Hepatic Lipid Droplets - a Potential Therapeutic Target for Fatty Liver Disease
$828,900
February 2021
Principal Investigator
Division
Sponsor
Title
Amount
Jon Klein, M.D., Ph.D.
Nephrology/
Hypertension
Jewish Heritage Fund for Excellence
Investing in Faculty Recruitment: The JHFE Startup Supplement Program 2021-2022
$600,000
Jewish Heritage Fund for Excellence
2021 - JHFE Research Enhancement Grants at the University of Louisville Health Sciences Center
$600,000
Theodore Smith, Ph.D.
Environmental Medicine
University of Kentucky Res. Fdn.
Covid 19:Wastewater Surveillance to Prevent SARS Cov2 Infection in Nursing Homes
$23,844
January 2021
Principal Investigator
Division
Sponsor
Title
Amount
Aruni Bhatnagar, Ph.D.
Environmental Medicine
Ky. Dept. of Corrections
Monitoring COVID-19 Infections in Correctional Facilities
$100,558
Ruth Carrico, Ph.D.
Infectious Diseases
Louisville/Jefferson Co Metro Government
Building Local Operational Capacity for COVID-19
$52,250
December 2020
Principal Investigator
Division
Sponsor
Title
Amount
Michael Brier, Ph.D.
Nephrology/
Hypertension
V.A. Medical Center
Michelle Barati IPA
$15,075.99
Jason Chesney, M.D., Ph.D.
Oncology/
Hematology
Ky. Council on Postsecondary Ed
FY21 & FY22 -Tobacco Settlement - UofL Cancer Research and Screening - Translational and Clinical Cancer Research Programs
$4,226,500
Ky. Council on Postsecondary Ed
FY21 & FY22 -Tobacco Settlement - UofL Cancer Research and Screening - New Faculty and Staff Recruitment
$1,429,600
Ky. Council on Postsecondary Ed
FY21 & FY22 - Tobacco Settlement - UofL Cancer Research and Screening - Clinical Trial and Cancer Screening Expansion
$1,220,000
November 2020
Principal Investigator
Division
Sponsor
Title
Amount
Ruth Carrico, Ph.D.
Infectious Diseases
Ky. Cabinet for Health & Family Service
COVID-19 Regional Training and Consultation Center
$3,454,660
October 2020
Principal Investigator
Division
Sponsor
Title
Amount
Jerry Yu, Ph.D.
Pulmonary
V.A. Medical Center
Chao Lei IPA Agreement
$47,614.14
Chi Li, Ph.D.
Oncology/
Hematology
American Lung Association
Inhibiting Lung Adenocarcinoma Growth by Inducing Apoptosis Independent of Bcl-2 Proteins
$75,000
Sanjay Srivastava, Ph.D.
Environmental Medicine
University of Washington
Using Fortilin Inhibitors to Block Atherosclerosis
$101,942
Aruni Bhatnagar, Ph.D.
Environmental Medicine
Boston University
Rapidly Advancing Discovery to Arrest the Outbreak of Youth Vaping (VAPERACE)
$1,645,560
September 2020
Principal Investigator
Division
Sponsor
Title
Amount
Wenke Feng, Ph.D.
Gastroenterology
National Institutes of Health
Mechanisms of Probiotics in Alcoholic Liver Disease
$2,181,238
Matthew Cave, M.D.
Gastroenterology
National Institutes of Health
Exposome and Precision Medicine in NAFLD
$1,871,727
August 2020
Principal Investigator
Division
Sponsor
Title
Amount
Aruni Bhatnagar, Ph.D.
Environmental Medicine
Ky. Cabinet for Health & Family Services
Covid-19 Wastewater Pilot Program
$22,294
Lou. Metro Public Health & Wellness
Louisville Metro Government Co_Immunity TESTING PROJECT
$3,003,403
Michael Brier, Ph.D.
Nephrology/
Hypertension
V.A. Medical Center
Adam Gaweda IPA
$106,434.03
Wenke Feng, M.D.
Gastroenterology
National Institutes of Health
Probiotic and Intestinal miR194 Regulation of Bile Acid Metabolism in Alcoholic Liver Disease
$32,130
Michael Merchant, Ph.D.
Nephrology/
Hypertension
University of Pittsburgh
Biomarkers of Alcoholic Hepatitis
$102,451
July 2020
Principal Investigator
Division
Sponsor
Title
Amount
Howard Donninger, M.D.
Oncology/
Hematology
University of Kentucky Res. Fdn.
A Novel Anti-IL-6 Inhibitor as a New Immunotherapeutic for Uveitis
$50,000
Yoannis Imbert-Fernandez, Ph.D.
Oncology/
Hematology
National Institutes of Health
Targeting 6-Phosphofructo-2-Kinase to Increase Efficacy of CDK4/6 Inhibitors
$356,850
Tamer Mohamed, Ph.D.
Cardiovascular Medicine
University of Kentucky Res. Fdn.
An Innovative Therapeutic Approach to Treat Cardiomyopathy
$64,133
Jerry Yu, Ph.D.
Pulmonary
V.A. Medical Center
IPA Agreement - Lu Cai
$15,522
V.A. Medical Center
IPA Agreement - Igor Zelko
$4,774
June 2020
Principal Investigator
Division
Sponsor
Title
Amount
Robert Emmons, M.D.
Oncology/
Hematology
Ky. Cabinet for Health & Family Services
FY21 & FY22 - Good Manufacturing Practices Facility
$900,000
May 2020
Principal Investigator
Division
Sponsor
Title
Amount
Tamer Mohamed, Ph.D.
Cardiovascular Medicine
National Institutes of Health
Induction of Cardiomyocyte Proliferation via Transient Expression of Cell Cycle Factors as a Promising Therapy for Heart Failure
$767,728
February 2020
Principal Investigator
Division
Sponsor
Title
Amount
Douglas Dean, Ph.D.
Oncology/
Hematology
National Institutes of Health
Blood Outer Retina Barrier Regulation
$594,101
Jon Klein, M.D., Ph.D.
Nephrology/
Hypertension
Jewish Heritage Fund for Excellence
JHFE Research Enhancement Grants
$600,000
January 2020
Principal Investigator
Division
Sponsor
Title
Amount
Jon Klein, M.D., Ph.D.
Nephrology/
Hypertension
Nationwide Children's Hospital
CUREGN 2.0 - Midwest Pediatric Nephrology Consortium - PCC
$13,726
Sanjay Srivastava, Ph.D.
Environmental Medicine
National Institutes of Health
Atherogenic Mechanisms of Electronic Nicotine Delivery Systems
$742,925
December 2019
Principal Investigator
Division
Sponsor
Title
Amount
Shirish Barve, Ph.D.
Gastroenterology
University of Florida
Health Outcomes and Cognitive Effects of Marijuana Use Among Persons Living With HIV/AIDS
$107,800
November 2019
Principal Investigator
Division
Sponsor
Title
Amount
Jerry Yu, Ph.D.
Pulmonary
V.A. Medical Center
Zhong-bin Deng IPA Agreement
$35,227
Andrew DeFilippis, M.D.
Cardiovascular Medicine
University of Kentucky Res. Fdn.
Understanding the Role of Anti-Apolipoprotein A-I Antibodies in Atherosclerotic Cardiovascular Disease
$51,965
Shizuka Uchida, Ph.D.
Environmental Medicine
Brigham & Women's Hospital
Pro-Inflammatory Activation of Human Macrophages Regulated by lncRNAs
$32,098
August 2019
Principal Investigator
Division
Sponsor
Title
Amount
Bradford Hill, Ph.D.
Cardiovascular Medicine
National Institutes of Health
Biosynthetic Pathways in Cardiac Remodeling
$763,757
Chi Li, Ph.D.
Oncology/
Hematology
U.S. Army Med Research Acq Activity
Identifying and Characterizing Neoantigens of an Embryonic Stem Cell-Based Lung Cancer Vaccine
$151,794
Jason Chesney, M.D., Ph.D.
Oncology/
Hematology
Susan G. Komen B. Cancer Fdn. Lou
Reducing Barriers to Breast Patient Care for Low Income and Rural Patients
$26,240
June 2019
Principal Investigator
Division
Sponsor
Title
Amount
Steven Jones, Ph.D.
Cardiovascular Medicine
National Institutes of Health
Imaging and Physiology Core: High Frequency, High Resolution, Ultrasound Imaging System
$363,800
April 2019
Principal Investigator
Division
Sponsor
Title
Amount
Joongho Joh, Ph.D.
Oncology/
Hematology
Massachusetts General Hospital
The Role of the Immune System in Skin Homeostasis and Prevention of Skin Aging
$13,531
March 2019
Principal Investigator
Division
Sponsor
Title
Amount
Marcin Wysoczynski, Ph.D.
Cardiovascular Medicine
National Institutes of Health
The Role of Bioactive Lipids in CMC-induced Myocardial Repair
$385,000
February 2019
Principal Investigator
Division
Sponsor
Title
Amount
Sanjay Srivastava, Ph.D.
Cardiovascular Medicine
Children's Hospital Boston
Molecular Regulation of Atherosclerosis
$169,400
January 2019
Principal Investigator
Division
Sponsor
Title
Amount
Aruni Bhatnagar, Ph.D.
Cardiovascular Medicine
National American Heart Association
ATRAC 2.0 - American Heart Association Tobacco Regulatory Science Center
$1,736,930
December 2018
Principal Investigator
Division
Sponsor
Title
Amount
Jerry Yu, Ph.D.
Pulmonary
V.A. Medical Center
Xia Yu IPA Agreement
$78,281
November 2018
Principal Investigator
Division
Sponsor
Title
Amount
Jason Chesney, M.D., Ph.D.
Oncology/
Hematology
Ky. Council on Postsecondary Ed
FY2019 & FY2020 - Cancer Research and Screening
$6,843,250
Ky. Council on Postsecondary Ed
FY2019 & FY2020 - Cancer Research Inst. Matching
$4,110,000
American Cancer Society
JGBCC M Krista Loyd Resource Center Transportation Fund
$15,000
Jon Klein, M.D., Ph.D.
Nephrology/
Hypertension
Jewish Heritage Fund
JHFE Research Enhancement Grants
$600,000
Jewish Heritage Fund
JHFE Research Recruitment
$600,000
Shirish Barve, Ph.D.
Gastroenterology
National Institutes of Health
Role of Gut Microbial Dysbiosis and Aging on HIV-Associated Neurocognitive and Brain Dysfunction
$779,748
October 2018
Principal Investigator
Division
Sponsor
Title
Amount
Eleanor Lederer, M.D.
Nephrology/
Hypertension
V.A. Medical Center
Michelle Barati IPA
$22,821
Craig McClain, M.D.
Gastroenterology
National Institutes of Health
Alcoholic Hepatitis Network 3/9 University of Louisville
$369,000
September 2018
Principal Investigator
Division
Sponsor
Title
Amount
Jason Chesney, M.D., Ph.D.
Oncology/
Hematology
Ky. Cabinet for Health & Family Services
FY19 & FY20 Adult Hemophilia Clinics
$30,000
Paula Bates, Ph.D.
Oncology/
Hematology
National Science Foundation
PFI-RP: Development of Delivery Devices to Enable Cell Transformation or Preservation
$750,000
Petra Haberzettl, Ph.D.
Cardiovascular Medicine
National Institutes of Health
Effects of Air Pollution on Stem Cell Health
$456,275
Jason Hellmann, Ph.D.
Cardiovascular Medicine
National Institutes of Health
Exercise-enhanced Resolution of Inflammation
$462,462
August 2018
Principal Investigator
Division
Sponsor
Title
Amount
Paula Bates, Ph.D.
Oncology/
Hematology
U.S. Department of Defense
Combining Immunotherapy with Nanoparticles for Improved Kidney Cancer Outcomes
$115,500
Zhong-bin Deng, Ph.D.
Oncology/
Hematology
National Institutes of Health
Gut Extracellular Vesicles Promote Alcohol-Induced Liver Injury via TLR4-Regulated miRNAs
$221,375
National Institutes of Health
CSN8 Regulation of S1P-Enriched Extracellular Vesicles to Modulate NAFLD by Gut-Liver Axis
$415,800
Jerry Yu, Ph.D.
Pulmonary
V.A. Medical Center
IPA Agreement - Igor Zelko (Yu PULM-024-17S The Vagus Nerve in Lung Disease)
$112,036
V.A. Medical Center
IPA Agreement - Lu Cai (Yu PULM-024-17S The Vagus Nerve in Lung Disease)
$19,276
July 2018
Principal Investigator
Division
Sponsor
Title
Amount
Aruni Bhatnagar, Ph.D.
Cardiovascular Medicine
National Institutes of Health
COBRE - Center for Excellence in Diabetes and Obesity Research
$1,115,000
The Nature Conservancy
Green Heart Project
$2,000,000
June 2018
Principal Investigator
Division
Sponsor
Title
Amount
Levi Beverly, Ph.D.
Oncology/
Hematology
Kentucky Lung Cancer Research Program
Understanding the Role of Gamma Secretase and Ubiquilin in Antigen Processing, Interferon Signaling and Immunotherapy
$75,000
Ruth Carrico, Ph.D.
Infectious Diseases
Kentucky Department for Public Health
UofL Ebola Stimulus FY19
$170,000
Howard Donninger, Ph.D.
Oncology/
Hematology
Kentucky Lung Cancer Research Program
Overcoming Lung Cancer MDSC-mediated Immune Suppression by Targeting IL-6 Signaling
$75,000
Chi Li, Ph.D.
Oncology/
Hematology
Kentucky Lung Cancer Research Program
Inhibit Non-Small Cell Lung Cancer Growth by Targeting Paraoxonase 2
$75,000
March 2018
Principal Investigator
Division
Sponsor
Title
Amount
Joseph Moore IV, Ph.D.
Cardiovascular Medicine
National Institutes of Health
The Role of Cardiomyogenic Lineage Commitment in Cardiac Mesenchymal Cell-Mediated Extracellular Vesicle Signaling and Cardiac Repair
$385,000
Timothy O'Toole, Ph.D.
Cardiovascular Medicine
National Institutes of Health
Endothelial Progenitor Cells and Particulate Air Pollution
$624,022
February 2018
Principal Investigator
Division
Sponsor
Title
Amount
Shirish Barve, Ph.D.
Gastroenterology
Vanderbilt University
1/2 Alcohol Associated Comorbidities and Microbiome Evaluation in HIV (ACME HIV)
$289,851
January 2018
Principal Investigator
Division
Sponsor
Title
Amount
Ruth Carrico, Ph.D., RN
Infectious Diseases
Catholic Charities
Refugee Health Surveillance
$30,000
Jon Klein, M.D., Ph.D.
Nephrology/
Hypertension
Jewish Heritage Fund
Jewish Heritage Fund for Excellence Research Enhancement Grant
$347,385
November 2017
Principal Investigator
Division
Sponsor
Title
Amount
Shirish Barve, Ph.D.
Gastroenterology
National Institutes of Health
2/2 Alcohol Associated Comorbidities and Microbiome Evaluation in HIV (ACME HIV)
$673,788
Matthew Cave, M.D.
Gastroenterology
National Institutes of Health
Environmental Liver Disease
$550,876
October 2017
Principal Investigator
Division
Sponsor
Title
Amount
Roberto Bolli, M.D.
Cardiovascular Medicine
National Institutes of Health
Protection of Ischemic Myocardium
$2,774,979
Sanjay Srivastava, Ph.D.
Cardiovascular Medicine
National Institutes of Health
Environmental Exposure and Cardiometabolic Disease - Admin Core
$1,335,021
September 2017
Principal Investigator
Division
Sponsor
Title
Amount
Jonathan Chaires, Ph.D.
Oncology/
Hematology
National Institutes of Health
Targeting Nucleic Acids with an Integrated Virtual and Actual Screen
$355,395
Craig McClain, M.D.
Gastroenterology
VA Medical Center
IPA-Lanceta CSP#577 CONFIRM VA Cooperative Study
$35,587
August 2017
Principal Investigator
Division
Sponsor
Title
Amount
Sanjay Srivastava, Ph.D.
Cardiovascular Medicine
University of Texas Medical Branch
Using Fortilin Inhibitors to Block Atherosclerosis
$123,200
Children's Hospital Boston
Molecular Mechanisms Regulating Endothelial Dysfunction
$200,200
Jun Yan, Ph.D.
Oncology/
Hematology
National Psoriasis Foundation
Regulation of Innate Gammadelta T17 Cells in Skin Inflammation
$100,000
July 2017
Principal Investigator
Division
Sponsor
Title
Amount
Steven Jones, Ph.D.
Cardiovascular Medicine
National American Heart Association
Louisville Cardiovascular Mentorship Program: Developing Independent Cardiovascular Investigators
$60,000
Zhong-bin Deng, Ph.D.
Oncology/
Hematology
National Institutes of Health
Intestinal Epithelial Cells-Derived Exosomal miRNA's Regulate Liver Inflammation in Obesity
$231,000
Mariusz Ratajczak, M.D., Ph.D.
Oncology/
Hematology
National Institutes of Health
Novel Mechanisms Involving Complement Cascade in Stem Cell Trafficking
$346,500
June 2017
Principal Investigator
Division
Sponsor
Title
Amount
Nichola Garbett, Ph.D.
Oncology/
Hematology
Wake Forest University
Theranostic Nanoparticles for Detection and Treatment of Pancreatic Cancer
$3,186
Wake Forest University
Stroma Targeted Theranostic Nanoparticles for Pancreatic Cancer
$5,461
Kavitha Yaddanapudi, M.D., Ph.D.
Oncology/
Hematology
Kentucky Lung Cancer Research Program
A Novel Immunotherapeutic Approach for the Treatment of Lung Cancer
$150,000
Mariusz Ratajczak, M.D., Ph.D.
Oncology/
Hematology
National Institutes of Health
Current Trends in Stem Cell Therapies
$128,751
Mark Rothstein, J.D.
Internal Medicine
National Institutes of Health
Addressing ELSI Issues in Unregulated Health Research Using Mobile Devices
$676,565
May 2017
Principal Investigator
Division
Sponsor
Title
Amount
Nichola Garbett, Ph.D.
Oncology/
Hematology
National Institutes of Health
Enhanced Diagnostic Assessment in Lupus Using Differential Scanning Calorimetry
$360,517
Petra Haberzettl, Ph.D.
Cardiovascular Medicine
National Institutes of Health
Air Pollution, Circadian Rhythm Disruption and Cardiometabolic Disease
$344,607
April 2017
Principal Investigator
Division
Sponsor
Title
Amount
Julio Ramirez, M.D.
Infectious Diseases
National Institutes of Health
Clinical and Translational Research in Pneumonia: Creating a Research Agenda for Today and Tomorrow
$5,000
John Trent, Ph.D.
Oncology/
Hematology
Kentucky Lung Cancer Research Program
Targeting the Human Telomere Complex in Lung Cancer
$150,000
Jun Yan, M.D., Ph.D.
Oncology/
Hematology
National Institutes of Health
Regulation of Dermal Gamma Delta T Cells by Pathogens/Microbial Commensals in Health and Psoriasis
$200,000
March 2017
Principal Investigator
Division
Sponsor
Title
Amount
Mark Pfiefer, M.D.
Internal Medicine
National Institutes of Health
Training in Interprofessional Education for Palliative Care in Oncology
$203,380
Craig McClain, M.D.
Gastroenterology
VA Medical Center
IPA - Mahanes - Dietary Fat & Alcoholic Liver Disease
$130,727
VA Medical Center
IPA - Warner - Dietary Fat & Alcoholic Liver Disease
$84,778
VA Medical Center
IPA - Mir-CSP#577 Confirm VA Cooperative Study
$123,854
Jon Klein, M.D., Ph.D.
Nephrology/
Hypertension
Nationwide Children's Hospital
Integrating Proteomics and Metabolomics to Understand Pediatric Glomerular Disease Pathophysiology and Prognosis
$250,784
February 2017
Principal Investigator
Division
Sponsor
Title
Amount
Jun Yan, Ph.D.
Oncology/
Hematology
National Institutes of Health
Transcriptional Regulation of Immunosupressive Macrophages by c-Maf in Cancer
$352,275
January 2017
Principal Investigator
Division
Sponsor
Title
Amount
Monica Ann Shaw, M.D.
Internal Medicine
Commonwealth of Kentucky
Trover Rural Scholarships for Class 2017 and 2018
$1,406,000
Vincent La Russa, Ph.D.
Cardiovascular Medicine
Indiana University
Stem Cell Manufacturing to Support STL16101Q Champ Pilot Study
$69,900
December 2016
Principal Investigator
Division
Sponsor
Title
Amount
Barbara Head, Ph.D., RN
Internal Medicine
Gordon and Betty Moore Foundation
Palliative and Hospice Social Worker Certification
$289,382
November 2016
Principal Investigator
Division
Sponsor
Title
Amount
Lacey McNally, Ph.D.
Oncology/
Hematology
National Institutes of Health
Theranostic Nanoparticles for Detection and Treatment of Pancreatic Cancer
$390,388
September 2016
Principal Investigator
Division
Sponsor
Title
Amount
Barbara Head, Ph.D., RN
Internal Medicine
Hospice and Palliative Nurses Foundation
Work and Compassion Satisfaction, Burnout and Secondary Trauma Among Hospice and Palliative Nurses: Does Certification Make a Difference?
$14,926
Paula Bates, Ph.D.
Oncology/
Hematology
Jewish Heritage Fund
New Approaches to Overcome Malignant Brain Tumors
$112,670
Thomas Abell, M.D.
Gastroenterology
National Institutes of Health
University of Louisville's Clinical Center in Gastroparesis Clinical Research Consortium
$383,920
Ruth Carrico, Ph.D., RN
Infectious Diseases
Catholic Charities
Refugee Health Promotion
$19,244
Shirish Barve, Ph.D.
Gastroenterology
National Institutes of Health
Role of Gut Microbiome and DHA Deficiency in Alcohol Induced Neuroinflammation
$337,500
August 2016
Principal Investigator
Division
Sponsor
Title
Amount
Madhavi Rane, Ph.D.
Nephrology
Johns Hopkins University
Targeting Divergent Roles of Caspase 3 to Promote Endothelial Barrier Integrity
$30,800
Matthew Nystoriak, Ph.D.
Cardiovascular Medicine
American Heart Association - Great Rivers Affiliate
Compartmentalized Camp Signaling in Diabetic Vascular Dysfunction
$77,000
Jerry Yu, Ph.D.
Pulmonary
Pulmonary Fibrosis Foundation
The Vagus Nerve in Pulmonary Fibrosis
$50,000
Donald Miller, M.D., Ph.D.
Oncology/
Hematology
Kentucky Cabinet for Health & Family Services
Y17 Adult Hemophilia Clinics
$15,000
Kentucky Council on Postsecondary Education
Kentucky Lung Cancer Research Program - Administration
$3,718,600
Kentucky Council on Postsecondary Education
Tobacco Tax Funding-Cancer Research Institute Matching FY17-18
$4,110,000
Lacey McNalley, Ph.D.
Oncology/
Hematology
National Institutes of Health
Non-invasive Detection of Tumor Extracellular pH Using Multispectral Optoacoustic Tomography
$350,293
July 2016
Principal Investigator
Division
Sponsor
Title
Amount
A. Gregory Deam, M.D.
Cardiovascular Medicine
Boston Scientific Corproation
Clinical Cardiac Electrophysiology Fellowship Program
$25,000
Medtronic, Inc.
Clinical Cardiac Electrophysiology Fellowship Program
$30,000
Umair Gauhar, M.D.
Pulmonary
Veracyte, Inc.
Percepta R-1 :Respective Registry to Evaluate Percepta Bronchial Genomic Classifier Patient Data: The PERCEPTA Registry
$1,888
Veracyte, Inc.
Bronchial Sample Collection for a Novel Genomic Test-3
$68,380.37
Craig McClain, M.D.
Gastroenterology
National Institutes of Health
Novel Therapies In Alcoholic Hepatitis University of Louisville
$261,000
National Institutes of Health
Mechanisms for Alcohol Induced Gut Barrier Dysfunction in ALD
$322,818
National Institutes of Health
Hepatobiology and Toxicology COBRE - Administrative Core
$2,608,500
Donald Miller, M.D., Ph.D.
Oncology/
Hematology
National Institutes of Health
Molecular Targets CoBRE Phase III - Core A
$1,052,312
Sanjay Srivastava, Ph.D.
Cardiovascular Medicine
National American Heart Association
ATRAC -CORE A - Adminstration
$86,169
Aruni Bhatnagar, Ph.D.
Cardiovascular Medicine
National Institutes of Health
COBRE - Administrative Core
$2,250,000
Paula Peyrani, M.D.
Infectious Diseases
Health Resources and Services Administration
University of Louisville HIV Early Interventions Service (EIS Program)
$333,918
Kentucky Department for Public Health
FEDERAL FY17-18 KHCCP - UofL 550 Clinic
$2,026,382
Kentucky Department for Public Health
STATE FY17-18 KHCCP - UofL 550 Clinic
$1,198,680
Kavitha Yaddanapudi, Ph.D.
Oncology/
Hematology
National Institutes of Health
A Novel Vaccination Stratagem for Lung Cancer
$163,125
Shirish Barve, Ph.D.
Gastroenterology
National Institutes of Health
SAM Deficiency Mediated Epigenetic Mechanisms in Alcohol Induced Immunosuppression - Supplement
$100,000
Irina Kirpich, Ph.D.
Gastroenterology
National Institutes of Health
The Role of Dietary Unsaturated Fat and Inflammasome in Alcoholic Liver Disease
$346,500
Andrew Gibb
Cardiovascular Medicine
American Heart Association - Great Rivers Affiliate
Metabolic Regulation of Myocardial Adaptations to Exercise
$51,900
Xian-Liang Tang, M.D.
Cardiovascular Medicine
EndoProtech, Inc.
A Novel Lipotherapy to Reduce Infarct Size Following Myocardial Infarction
$69,253
