Vivek R. Sharma, M.D., FACP

Vivek R. Sharma, M.D.

Vivek R. Sharma, M.D., FACP

  • Professor of Medicine
  • Director, Adult Hemophilia Program
  • Director, Medical Oncology Service, GI Cancer Multidisciplinary Clinic
UofL Health - Brown Cancer Center
529 South Jackson Street
Louisville, KY 40202

502-852-2522 - Academic Office
502-562-4370 - Patient Appointments


Clinical Expertise
Medical Oncology - Gastrointestinal; Hemophilia and Other Benign Hematology


Board Certifications

  • American Board of Internal Medicine -
    Internal Medicine / Medical Oncology / Hematology

Education and Training

  • Medical School: B.J. Medical College, University of Poona
  • Residency: University of Louisville Hospital
  • Fellowship: University of Louisville

Featured Publications

  • Chrisentery-Singleton T, Boggio LN, Carcao MD, Ibrahimi S, Khan O, Mahajerin A, Rajasekhar A, Sharma V, Steele M, Torres M, Rodino FJ, Carpenter SL. Long-term follow-up of patients with congenital thrombotic thrombocytopenia purpura receiving a plasma-derived factor VIII (Koate) that contains ADAMTS13. Haemophilia. 2023 Nov;29(6):1638-1645. doi: 10.1111/hae.14891. Epub 2023 Oct 19. PMID: 37855744.
  • Sharma V, Koprivnikar J, Drago K, Savage J, Bachelor A. Injection Site Reactions with Long-Term Pegcetacoplan Use in Patients with Paroxysmal Nocturnal Hemoglobinuria: A Brief Report. Adv Ther. 2023 Nov;40(11):5115-5129. doi: 10.1007/s12325-023-02653-4. Epub 2023 Sep 14. PMID: 37707673; PMCID: PMC10567944.
  • Martin RCG 2nd, Simo KA, Hansen P, Rocha F, Philips P, McMasters KM, Tatum CM, Kelly LR, Driscoll M, Sharma VR, Crocenzi TS, Scoggins CR. Drug-Eluting Bead, Irinotecan Therapy of Unresectable Intrahepatic Cholangiocarcinoma (DELTIC) with Concomitant Systemic Gemcitabine and Cisplatin. Ann Surg Oncol. 2022 Sep;29(9):5462-5473. doi: 10.1245/s10434-022-11932-3. Epub 2022 Jun 3. PMID: 35657463.
  • Tiwari NR, Arora S, Tolat AG, Shaheen SP 2nd, Sharma VR. TTP or complement-mediated TMA or both? A rare diagnosis and report of a novel plasminogen gene variant. Ann Hematol. 2022 Mar;101(3):725-727. doi: 10.1007/s00277-021-04589-7. Epub 2021 Jul 16. PMID: 34268611.
  • Tiwari NR, Redewad NK, Ketkar AA, Sharma VR. Elevated plasma hemoglobin in COVID-19-related illnesses: a critical appraisal. Ann Hematol. 2021 Aug;100(8):2125-2126. doi: 10.1007/s00277-020-04281-2. Epub 2020 Sep 24. PMID: 32974839; PMCID: PMC7515552.
  • Maharaj S, Saenz Ayala S, Hu X, Chang S, Sharma V, Majerus J, Pruthi R. Novel splicing (c.6529-1G>T) and missense (c.1667G>A) mutations causing factor V deficiency. Blood Coagul Fibrinolysis. 2021 Jul 1;32(5):344-348. doi: 10.1097/MBC.0000000000001036. PMID: 33769317.
  • Tiwari NR, Phatak S, Sharma VR, Agarwal SK. COVID-19 and thrombotic microangiopathies. Thromb Res. 2021 Jun;202:191-198. doi: 10.1016/j.thromres.2021.04.012. Epub 2021 Apr 20. PMID: 33894421; PMCID: PMC8055926.
  • Wilson JA, Hayden S, Asamoah A, Sharma VR, Jennings DC, Raj AB. Emicizumab Associated Rhabdomyolysis in Hemophilia A. Clin Hematol Int. 2020 Oct 7;2(4):165-167. doi: 10.2991/chi.k.200924.001. PMID: 34595457; PMCID: PMC8432407.
  • de Castro C, Grossi F, Weitz IC, Maciejewski J, Sharma V, Roman E, Brodsky RA, Tan L, Di Casoli C, El Mehdi D, Deschatelets P, Francois C. C3 inhibition with pegcetacoplan in subjects with paroxysmal nocturnal hemoglobinuria treated with eculizumab. Am J Hematol. 2020 Nov;95(11):1334-1343. doi: 10.1002/ajh.25960. Epub 2020 Sep 11. PMID: 33464651; PMCID: PMC7693064.
  • Tiwari NR, Chaudhari KS, Rao V, Sharma VR. Nuances in the management of acquired hemophilia A in an elderly patient with large granular lymphocytic leukemia. Blood Res. 2020 Sep 30;55(3):180-181. doi: 10.5045/br.2020.2020093. PMID: 32792468; PMCID: PMC7536565.