Donald M. Miller, M.D., Ph.D.

Donald M. Miller, M.D., Ph.D.

Donald M. Miller, M.D., Ph.D.

UofL Health - Brown Cancer Center
529 South Jackson Street
Louisville, KY 40202

502-852-2522 - Academic Office
502-562-4370 - Patient Appointments


Clinical Expertise
Head and Neck; Medical Oncology; Skin Cancer; Melanoma


Board Certifications

  • American Board of Internal Medicine -
    Internal Medicine

Education and Training

  • Medical School: Duke University
  • Residency: Peter Bent Brigham Hospital (Boston)
  • Fellowship: Harvard University
  • Ph.D.: Duke University

Featured Publications

  • Miller DM, Yadanapudi K, Rai V, Rai SN, Chen J, Frieboes HB, Masters A, McCallum A, Williams BJ. Untangling the web of glioblastoma treatment resistance using a multi-omic and multidisciplinary approach. Am J Med Sci. 2023 Jun 15:S0002-9629(23)01226-0. doi: 10.1016/j.amjms.2023.06.010. Epub ahead of print. PMID: 37330006.
  • Miller HA, Miller DM, van Berkel VH, Frieboes HB. Evaluation of Lung Cancer Patient Response to First-Line Chemotherapy by Integration of Tumor Core Biopsy Metabolomics with Multiscale Modeling. Ann Biomed Eng. 2023 Apr;51(4):820-832. doi: 10.1007/s10439-022-03096-8. Epub 2022 Oct 12. PMID: 36224485; PMCID: PMC10023290.
  • Maharaj S, Jain N, Al Bawaliz A, Miller D, Chesney J. Melanoma of unknown primary: favorable survival persists in the immunotherapy era. Int J Dermatol. 2023 Apr;62(4):e236-e238. doi: 10.1111/ijd.16419. Epub 2022 Aug 28. PMID: 36030543.
  • Sharma M, Wang D, Palmisciano P, Ugiliweneza B, Woo S, Nelson M, Miller D, Savage J, Boakye M, Andaluz N, Mistry AM, Chen CC, Williams BJ. Is intraoperative MRI use in malignant brain tumor surgery a health care burden? A matched analysis of MarketScan Database. J Neurooncol. 2022 Nov;160(2):331-339. doi: 10.1007/s11060-022-04142-0. Epub 2022 Oct 26. PMID: 36289149.
  • Elmasry M, Dong B, Rios C, Breaux A, Miller D. Delayed hemorrhagic gastritis caused by immunotherapy in a patient With metastatic melanoma. Am J Med Sci. 2022 Sep;364(3):343-346. doi: 10.1016/j.amjms.2022.02.010. Epub 2022 Mar 8. PMID: 35276075.
  • Terry M, Wakeman K, Williams BJ, Miller DM, Sak M, Abdullaev Z, Pacheco MC, Aldape K, Lehman NL. Malignant melanotic nerve sheath tumor with PRKAR1A, KMT2C, and GNAQ mutations. Free Neuropathol. 2022 Aug 26;3:3-21. doi: 10.17879/freeneuropathology-2022-3864. PMID: 37284154; PMCID: PMC10209877.
  • Yusuf M, Rattani A, Gaskins J, Oliver AL, Mandish SF, Burton E, May ME, Williams B, Ding D, Sharma M, Miller D, Woo S. Stereotactic radiosurgery for melanoma brain metastases: dose-size response relationship in the era of immunotherapy. J Neurooncol. 2022 Jan;156(1):163-172. doi: 10.1007/s11060-021-03899-0. Epub 2021 Nov 22. PMID: 34807342; PMCID: PMC8606626.
  • Chen J, Lee H, Schmitt P, Choy CJ, Miller DM, Williams BJ, Bearer EL, Frieboes HB. Bioengineered Models to Study Microenvironmental Regulation of Glioblastoma Metabolism. J Neuropathol Exp Neurol. 2021 Nov 19;80(11):1012–1023. doi: 10.1093/jnen/nlab092. Epub 2021 Sep 15. PMID: 34524448; PMCID: PMC9432143.
  • Yusuf MB, McKenzie G, Rattani A, Tennant P, Bumpous J, Miller D, Dunlap N. Merkel Cell Carcinoma of the Head and Neck: Epidemiology, Pathogenesis, Current State of Treatment and Future Directions. Cancers (Basel). 2021 Jul 13;13(14):3506. doi: 10.3390/cancers13143506. PMID: 34298720; PMCID: PMC8305628.
  • Miller HA, Yin X, Smith SA, Hu X, Zhang X, Yan J, Miller DM, van Berkel VH, Frieboes HB. Evaluation of disease staging and chemotherapeutic response in non-small cell lung cancer from patient tumor-derived metabolomic data. Lung Cancer. 2021 Jun;156:20-30. doi: 10.1016/j.lungcan.2021.04.012. Epub 2021 Apr 15. PMID: 33882406; PMCID: PMC8138715.