Matthew C. Cave, M.D.

Matthew C. Cave, M.D.
- Associate Professor of Medicine
401 East Chestnut Street, Ste. 310
Louisville, KY 40202
502-852-6991 - Academic Office
502-588-4600 - Patient Appointments
E-mail Dr. Cave
Clinical Expertise
Hepatology; Nutrition; Liver Transplantation
Board Certifications
- American Board of Internal Medicine -
Gastroenterology / Transplant Hepatology
Education and Training
- Medical School: University of Kentucky
- Residency: Washington University Barnes-Jewish Hospital
- Fellowship: University of Louisville
Featured Publications
- Hardesty JE, Al-Eryani L, Wahlang B, Falkner KC, Shi H, Jin J, Vivace BJ, Ceresa BP, Prough RA, Cave MC. Epidermal Growth Factor Receptor Signaling Disruption by Endocrine and Metabolic Disrupting Chemicals. Toxicol Sci. 2018 Apr 1;162(2):622-634. doi: 10.1093/toxsci/kfy004. PubMed PMID: 29329451; PubMed Central PMCID: PMC5888991.
- Guardiola JJ, Beier JI, Falkner KC, Wheeler B, McClain CJ, Cave M. Occupational exposures at a polyvinyl chloride production facility are associated with significant changes to the plasma metabolome. Toxicol Appl Pharmacol. 2016 Dec 15;313:47-56. doi: 10.1016/j.taap.2016.10.001. Epub 2016 Oct 17. PubMed PMID: 27765658; PubMed Central PMCID: PMC5712227.
- Cave MC, Clair HB, Hardesty JE, Falkner KC, Feng W, Clark BJ, Sidey J, Shi H, Aqel BA, McClain CJ, Prough RA. Nuclear receptors and nonalcoholic fatty liver disease. Biochim Biophys Acta. 2016 Sep;1859(9):1083-1099. doi: 10.1016/j.bbagrm.2016.03.002. Epub 2016 Mar 4. Review. PubMed PMID: 26962021; PubMed Central PMCID: PMC5149456.
- Anders LC, Lang AL, Anwar-Mohamed A, Douglas AN, Bushau AM, Falkner KC, Hill BG, Warner NL, Arteel GE, Cave M, McClain CJ, Beier JI. Vinyl Chloride Metabolites Potentiate Inflammatory Liver Injury Caused by LPS in Mice. Toxicol Sci. 2016 Jun;151(2):312-23. doi: 10.1093/toxsci/kfw045. Epub 2016 Mar 8. PubMed PMID: 26962056; PubMed Central PMCID: PMC4880135.
- Wahlang B, Prough RA, Falkner KC, Hardesty JE, Song M, Clair HB, Clark BJ, States JC, Arteel GE, Cave MC. Polychlorinated Biphenyl-Xenobiotic Nuclear Receptor Interactions Regulate Energy Metabolism, Behavior, and Inflammation in Non-alcoholic-Steatohepatitis. Toxicol Sci. 2016 Feb;149(2):396-410. doi: 10.1093/toxsci/kfv250. Epub 2015 Nov 25. PubMed PMID: 26612838; PubMed Central PMCID: PMC4751229.