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Guidance for Preparing Safe Operating Procedures

by schmidy last modified Jan 07, 2008 10:48 AM

  1. Working Principle: Describe the mechanism of action and the anticipated outcome for the highly hazardous chemicals being used.

  2. Potential Hazards: Discuss the potential for the material to harm human health. Provide the quantity that constitutes a pharmacologically significant dose, if known. For hazardous chemicals include a brief discussion of acute and chronic toxicity and routes of entry. Some of this information may be found on a Material Safety Data Sheet (MSDS).

  3. Regulatory Review: List any Occupational Safety and Health Administration (OSHA) regulations and any occupational exposure limits or special requirements. OSHA Permissible Exposure Limits (PELs) must be listed on the MSDS.

  4. Training: Discuss training, general and lab-specific. Discuss what measures will be put in place to ensure that all personnel in the work area are aware of the potential hazards of this chemical.

  5. Chemical Security: Discuss methods to secure access to the chemical, such as lock boxes, locked doors when lab is unoccupied, etc.

  6. Controlling Exposure: Identify a "Designated Area" for use with carcinogens, reproductive toxins, or chemicals with high degree of acute toxicity, and posting of warning signs. Mention controls to be in place to reduce exposure to lab workers, such as use of a chemical fume hood and administrative controls.

  7. Personal Protective Equipment: Define what personal protective equipment must be worn.

  8. Spill Control: Describe procedures for managing spills including the proper PPE to be worn and disposal methods. State that for large spills the lab workers don't feel comfortable cleaning up, call 852-6111 for emergencies. Notify those affected and evacuate. DEHS will respond to a large chemical spill.

  9. Waste Disposal: Describe procedures for following the UofL Waste Disposal Procedures. List the wording to be written on the container of waste, including the words "Hazardous Waste." The Chemical Waste Pick Up Form is available on the Department of Environmental Health and Safety website. Contact the Hazardous Waste Coordinator at 852-2956.

  10. Emergency Procedures: Information concerning emergency procedures for exposure or accident contact with highly hazardous chemicals is usually provided on the MSDS. List those procedures along with emergency phone numbers.
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