Research Interests

Clinical Trials, Survival Analysis, Mixed Effects (Hierarchical) Model, Sample Survey, Bioinformatics, Quantitative Risk Assessment

Publications: Journal Articles

89. Rai SN and Sun J. Truncation in Time to Event Data. (Chapter XX). In: Everitt B and Melnick, E (Ed.), Encyclopedia of Quantitative Risk Assessment. Wiley and Sons. (pp. xx-xx), 2008 (In Press).

88.Rai SN and Sun J. Types of Censoring In Time to Event Data. (Chapter XX). In: Everitt B and Melnick, E (Ed.), Encyclopedia of Quantitative Risk Assessment. Wiley and Sons. (pp. xx-xx), 2008 (In Press).

87. Pounds S and Rai SN. Assumption Adequacy Averaging as a Concept to Develop Robust Methods for Differential Gene Expression Analysis. Computational Statistics and Data Analysis, 2008 (In Press).

86. Rai SN. Uncertainty and Variability Characterization and Measures in Risk Assessment. (Chapter XX). In: Everitt B and Melnick, E (Ed.), Encyclopedia of Quantitative Risk Assessment. Wiley and Sons. (pp. xx-xx), 2008 (In Press).

85. Rai SN, Hudson MM, McCammon E, Carbone L, Tylavsky F, Smith K, Surprise H, Shelso J, Chin-Hon Pui, and Kaste S. Implementing an intervention to improve bone mineral density in survivors of childhood acute lymphoblastic leukemia: BONEII, a prospective placebo-controlled double-blind randomized interventional longitudinal study design. Contemporary Clinical Trials. In Press, 2008.

84. Rai SN. Risk Characterization. (Chapter XX). In: Everitt B and Melnick, E (Ed.), Encyclopedia of Quantitative Risk Assessment. Wiley and Sons. (pp. xx-xx), 2008 (In Press).

83. Rai SN. Analysis of Occult Tumor Studies. (Chapter 18). In: Tan WY (Ed.), Handbook of Cancer Models with Applications to Cancer Screening, Cancer treatment and Risk Assessment. World Scientific Press. (pp. xx-xx), 2008 (In Press).

82. Kaste SC, Thomas NA, Rai SN, Cheon K, McCammon E, Chesney R, Jones D, Pui CH, Hudson, MM. Asymptomatic Kidney Stones in Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia. Leukemia, Accepted, 2008.

81. Hunt DL and Rai SN. Interlitter Response Variability in a Threshold Dose-Response Model. Communications in Statistics – Theory and Methods, 37(14):2304-2314, 2008.

80. Metzger ML, Castellino SM, Hudson MM, Rai SN, Kaste SC Krasin MJ, Kun LE, Pui CH, Howard SC. Effect of Race on the Outcome of Pediatric Patients with Hodgkin Lymphoma. Journal of Clinical Oncology, 26(8):1282-1288, 2008.

79. Phipps S, Rai SN, Leung WH, Lensing S and Dunavant M. Cognitive and Academic Consequences of Stem-Cell Transplant in Children. Journal of Clinical Oncology, 26(12):2027-2033, 2008.

78. Cox CL, Montgomery M, Rai SN, McLaughlin R, Steen B and Hudson M. Supporting Breast Self-Examination in Female Childhood Cancer Survivors: A Secondary Analysis of Behavioral Intervention. Oncology Nursing Forum, 35 (3):423-430, 2008.

77. Marchese VG, Connolly BH, Able C, Booten AR, Bowen P, Porter BM, Rai SN, Hancock ML, Pui CH, Howard S, Neel MD, Kaste S. Relationship among severity of osteonecrosis, pain, range of motion, and functional mobility in children, adolescents, and young adults with acute lymphoblastic leukemia. Physical Therapy, 88(3):341-350, 2008.

76. Cox CL, Rai SN, Montgomery M, Rosenthal D, Phipps, S and Hudson M. Subclinical Late Cardiac Toxicity in Childhood Cancer Survivors: Impact on Quality of Life. Cancer, 112(8):1835-844, 2008.

75. Crom DB, Lensing SY, Rai SN, Snider MA, Cash DK and Hudson MM. The Attainment of Life Goals by Adult Survivors of Childhood Cancer. Journal of Cancer Survivorship, 1:237-245, 2007.

74. Crom DB, Lensing SY, Rai S, Snider M, and Hudson MM. The Attainment of Life Goals by Adult Survivors of Childhood Cancer. Journal of Clinical Oncology, 2007 ASCO Annual Meeting proceedings, 25 (18S) (June 20 Supplement), 9536, 2007.

73. Workman GM, Ribeiro RC, Pedrosa A, Rai SN, Workman DE, and Pedrosa F. Pediatric Cancer Knowledge: Assessment of knowledge of warning signs for pediatric cancer among Brazilian health care workers. Journal of Cancer Education, 22 (3): 181-185, 2007.

72. Hinds PS, Rai, SN, Hockenberry M, Gattuso JS, McCarthy K, Tong X and Srivastava DK. Validity and reliability of a new instrument to measure cancer-related fatigue in adolescents. Journal of Pain and Symptom Management, 34(6):607-618, 2007.

71. Ginsberg JP, Rai SN, Carlson CA, Meadows AT, Hinds PS, Spearing EM, Zhang L, Callaway L, Neel MD, Rao BN, Marchese VG,. Functional Outcomes: A Comparative Analysis of Adolescents and Young Adults with Lower-Extremity Sarcoma. Pediatric Blood and Cancer, 49(7):964-969, 2007.

70. Hinds PS, Hockenberry M, Rai SN, Zhang L, Razzouk BI, Cremer L, McCarthy K, Rodriguez-Galindo C. Clinical Field Testing of an Enhanced-Activity Intervention in Hospitalized Children with Cancer. Journal of Pain and Symptom, 33(6): 686-697, 2007.

69. Hudson MM, Rai SN, Nunez C, Merchant TE, Marina N, Zalamea N, Cox C, Phipps S, Pompeu R and Rosenthal D. Non-Invasive Evaluation of Late Anthracycline Cardiac Toxicity in Childhood Cancer Survivors. Journal of Clinical Oncology, 25 (24): 3635-3643, 2007.

68. Srivastava DK, Rai SN and Pan J. Robustness of Odds-ratio in a Stratified Group Sequential Trial with Binary Outcome Measure. Biometrical Journal, 49(3): 351-364, 2007.

67. Srivastava DK, Boyett, JM, Jackson, JW, Tong X, and Rai SN. A Comparison of Permutation Hotelling’s T2 Test and Log-Ratio Test for Analyzing Compositional. Data. Communications in Statistics – Theory and Methods, 36: 415-431, 2007.

66. Hoffer FA, Hancock ML, Hinds, PS, Oigbokie N, Rai SN, and Rao B. Pleurodesis for Effusions in Pediatric Oncology Patients at End of Life. Pediatric Radiology, 37(3), 269-273, 2007.

65. Donaldson SS, Link MP, Weinstein HJ, Brain S, Rai SN, Billett AL, Hurwitz CA, Krasin M, Kun LE, Marcus KC, Tarbell NJ, Young JA, and Hudson MM. End Results of a Prospective Clinical Trial with VAMP and Low-Dose Involved Field Radiation for Children with low risk Hodgkin’s disease. Journal of Clinical Oncology, 25(3), 332-337, 2007.

64. Garvie PA, Lensing S and Rai SN. Efficacy of a Pill Swallowing Training Intervention in Treating Pediatric HIV/AIDS. Pediatrics, 119(4): 893-899, 2007.

63. Hinds PS, Hockenberry M, Rai SN, Zhang L, Razzouk B, McCarthy K, Cremer L and Rodríguez-Galindo C. Nocturnal Awakenings, Sleep Environment Interruptions, and Fatigue in Hospitalized Children with Cancer. Oncology Nursing Forum, 34(2): 393-402, 2007.

62. Karimova JE, Rai SN, Howard, SC, Neel MD Britton L and Kaste SC. Outcomes of femoral head osteonecrosis in 80 pediatric and young adult patients with leukemia or lymphoma. Journal of Clinical Oncology, 25(12): 1525-1531, 2007.

61. Marchese VG, Rai SN, Carlson CA, Hinds PS, Spearing E, Zhang L, Callaway L, Neel MD, Rao BN, Ginsberg JP. Assessing Functional Mobility in Survivors of Lower Extremity Sarcoma: Reliability and Validity of a New Tool. Pediatric Blood and Cancer, 49(2):183-189, 2007.

60. Marchese VG, Spearing E, Callaway L, Rai SN, Hinds PS, Zhang L, Hinds PS, Carlson CA, Neel MD, Rao BN, Ginsberg J. Relationships among Range of Motion, Functional Mobility and Quality of Life in Children and Adolescent after Limb-sparing Surgery for Lower-extremity Sarcoma. Pediatric Physical Therapy, 18 (4), 238-244, 2006.

59. Crom DB, Tyc VL, Rai SN, Deng X, Hudson MM, Booth A, Rodrigues LN, Zhang L, McCammon E and Kaste SC. Retention of Survivors of Acute Lymphoblastic Leukemia in a Longitudinal Study of Bone Mineral Density. Journal of Child Health Care, 10(4), 337-350, 2006.

58. Khan RB, Gutin PH, Rai SN, Zhang L, Krol G, DeAngelis LM. Diffusion Postoperative Neurologic Deficits and Incomplete Recovery in Brain Tumor Patients. Neurosurgery, 59(1), 60-66, 2006.

57. Hinds P and Rai SN. To the Commentary by Furlong & Barr on Cox CL, Lensing S, Rai SN, et al. “Proxy assessment of quality of life in pediatric trials: Application of the Health Utilities Index 3”. Quality of Life Research. 15(7):1295-1296, 2006.

56. Kaste S, Rai SN, Fleming K, McCammon E, Tylavsky F, Danish R, Sitter C, Pui C and Hudson M. Factors Predictive of Bone Mineral Change in Survivors of Childhood Acute Lymphoblastic Leukemia. Pediatric Blood & Cancer, 46(1):77-87, 2006.

55. Phipps S, Larson S, Long A and Rai SN. Adaptive Style and Symptoms of Post-traumatic Stress in Children with Cancer and Their Parents, Journal of Pediatric Psychology, 31(3): 298-309, 2006.

54. Karimova JE, Rai SN, Britton L, Neel MD and Kaste SC. Part 2: Clinical and MR Imaging Patterns of Knee Osteonecrosis in Pediatric Patients with Hematological Malignancies American Journal of Roentgenology, 186(2):477-82, 2006.

53. Karimova JE, Rai SN, Britton L, Neel MD and Kaste SC. Part 1: MR Imaging of Knee Osteonecrosis in Children with Leukemia and Lymphoma: Observer Agreement. American Journal of Roentgenology, 186(2):470-6, 2006.

52. Tyc VL, Lensing S, Rai SN, Klosky J, Stewart DB and Gattuso J. Predicting Perceived Vulnerability to Tobacco-Related Health Risks and Future Intentions to Use Tobacco Among Pediatric Cancer Survivors. Patient Education and Counseling, 62(2):198-204, 2006.

51. Phipps S, Dunavant M, Gray E and Rai SN. Massage Therapy in Children Undergoing Hematopoietic Stem Cell Transplant: Results of a pilot trial. Journal of Cancer Integrative Medicine. 3(1):62-70, 2005.

50. Krasin MJ, Rai SN, Kun LE, Merchant TE, Metzger ML, Kaste SC, Howard SC and Hudson MM. Patterns of Treatment Failure in Pediatric and Young Adult Patients with Hodgkin’s Disease: Local Disease Control with Combined Modality Therapy. Journal of Clinical Oncology, 23(33):8406-8413, 2005.

49. Phipps S, Dunavant M, Lensing S and Rai SN. Psychosocial Predictors of Distress in Parents of Children Undergoing Stem Cell Transplantation. Journal of Pediatric Psychology, 30(2):139-153, 2005.

48. Phipps S, Long A, Hudson MM and Rai SN. Symptoms of Post-traumatic Stress in Children with Cancer and Their Parents: Effects of Informant and Time from Diagnosis. Pediatric Blood & Cancer, 45(7):952-959, 2005.

47. Hunt D and Rai SN. A New Threshold Dose-Response Model including Random Effects for Data from Developmental Toxicity Studies. Journal of Applied Toxicology. 25(5):435-439, 2005.

46. Hunt, D. and Rai, S.N. Testing Threshold and Hormesis in a Random Effects Dose-Response Model Applied to Developmental Toxicity Data. Biometrical Journal. 47(3):319-328, 2005.

45. Hinds PS, Gattuso JS, Fletcher A, Baker E, Coleman B, Jackson T, Jacobs-Levine A, June D, Rai S, Lensing S, Pui CH. Quality of life: The child's voice. SOCRA. 46, 18-22, 2005.

44. Cox CL, Rai SN McLaughlin R, Steen B and Hudson M. Adolescent Survivors: A Secondary Analysis of a Clinical Trial Targeting Behavior Change. Pediatric Blood & Cancer. 45 (2):144 -154, 2005.

43. Cox CL, Lensing S, Rai SN, Burghen L, Hinds P, Pui CH. Proxy-assessed Health Utilities in Pediatric Clinical Trials. Quality of Life Research. 14(4): 1045 – 1056, 2005.

42. Tyc VL, Lensing S, Klosky JL, Rai SN and Robinson L. A Comparison of Tobacco-Related Risk Factors between Adolescents with and without Cancer. Journal of Pediatric Psychology, 30(4):359-370, 2005.

41. Rai SN, Lensing S, Boyett J and Phipps S. On the Analysis of Messy Longitudinal Data from a Study of Pediatric Cancer Patients. Proceedings of Joints Statistical Meetings 2004, Biometrics Section, pages 427-433, 2004.

40. Hudson MM, Krasin M, Link MP, Donaldson SS, Billups C, Merchant T, Kun L, Billet AL, Kaste S, Tarbell NJ, Howard S, Friedmann AM, Hurwitz CA, Young JA, Marcus KC, Rai SN, Cowan T and Weinstein HJ. Risk-adapted Combined Modality Therapy with VAMP/COP and Response-based, Involved-field Radiation for Unfavorable Pediatric Hodgkin’s disease. Journal of Clinical Oncology. 22(22): 4541-4550, 2004.

39. Tyc VL, Throckmorton-Belzer L, Klosky J, Lensing S, Rai SN and Hudson MM. Smoking among parents of pediatric cancer patients and children's exposure to environmental tobacco smoke. Journal of Child Health Care. 8(4):288-300, 2004.

38. Phipps S, Dunavant M, Lensing S and Rai SN. Patterns of Distress in Parents of Children Undergoing Stem Cell Transplant. Pediatric Blood & Cancer. 43(3):267-74, 2004.

37. Tyc VL, Klosky J, Throckmorton-Belzer L, Lensing S, and Rai SN. Parent-Reported Environmental Tobacco Smoke Exposure among Preadolescents and Adolescents Treated for Cancer. Psycho-Oncology. 13(8):537-46, 2004.

36. Tyc VL, Hadley W, Allen D, Varnell S, Ey S, Rai SN and Lensing S. Predictors of Smoking Intentions and Smoking Status among Non-Smoking and Smoking Adolescents. Addictive Behaviors, 29(6):1143-1147, 2004.

35. Paul SR, Jiang X, Rai SN and Balasooriya U. Test of treatment effect in pre-drug and post-drug count data with zero-inflation. Statistics in Medicine, 23(10):1541-1554, 2004.

34. Castellino S, Lensing S, Riely C, Rai SN, Davila R, Hayeden RT, Fleckenstein J, Levstik M, Taylor S, Dean PJ, Kippenbrock S, Pope J, Carr J, Strickland DK and Hudson MM. The Epidemiology of Chronic Hepatitis C Infection in Survivors of Childhood Cancer – An Update of the St. Jude Children’s Research Hospital Hepatitis C Seropositive Cohort. Blood, 103(7): 2460 -2466, 2004.

33. Hinds PS, Gattuso JS, Fletcher A, Baker E, Coleman B, Jackson T, Jacobs-Levine A, June D, Rai SN, Lensing S and Pui CH. Quality of Life as Conveyed by Pediatric Patients with Cancer. Quality of Life Research, 13(4): 761-772, 2004.

32. Gow KW, Lensing S, Hill DA, Krasin MJ, McCarville MB, Rai SN, Zacher M, Spunt SL, Shearer P, Strickland DK, Pratt CB and Hudson MM. Thyroid Carcinoma Presenting in Childhood or After Treatment of Childhood Malignancies: An Institutional Experience and Review of the Literature. Journal of Pediatric Surgery, 38(11):1574–80, 2003.

31. Pui C, Cheng C, Leung W, Rai SN, Rivera GK, Sandlund JT, Ribeiro RC, Relling MV, Kun LE, Evans WE and Hudson MM. Extended Follow-up of Long-term Survivors of Childhood Acute Lymphoblastic Leukemia. The New England Journal of Medicine, 349:640-649, 2003.

30. Tyc VL, Rai SN, Lensing S, Klosky J, Stewart DB and Gattuso J. An Intervention to Reduce Intensions to Use Tobacco among Pediatric Cancer Survivors. Journal of Clinical Oncology, 21(7):1366-1372, 2003.

29. Hunt D. and Rai SN. A Threshold Dose-Response Model with Random Effects in Teratological Experiments. Communications in Statistics – Theory and Methods, 32:1439-1457, 2003.

28. Lusting RL, Hinds PS, Smith HK, Christensen RK, Kaste SC, Schreiber RE, Rai SN, Lensing SY, Wu S and Xiong X. Octreotide therapy of pediatric hypothalamic obesity: A double-blind, placebo-controlled trial. The Journal of Clinical Endocrinology and Metabolism, 88(6):2586-2592, 2003.

27. Kovacevic MS and Rai SN. A Pseudo Maximum Likelihood Approach to Multilevel Modelling of Survey Data. Communications in Statistics – Theory and Methods. 32(1):103-121, 2003.

26. Rai SN, Sun J and Hunt D. Analysis of Occult Tumour Trial Data with Varying Lethality. In: Recent Advances in Statistical Methods, (Ed.) Y. P. Chaubey, World Scientific Publishing, London, 233-251, 2002.

25. Kovacevic MS and Rai SN. Log-Linear Modeling of Change Using Longitudinal Survey Data. Communications in Statistics – Theory and Methods. 31(10):1815-1835, 2002.

24. Phipps S, Dunavant M, Lensing S and Rai SN. Acute Health-Related Quality of Life in Children Undergoing Stem Cell Transplant: II. Medical and Demographic Determinants. Bone Marrow Transplant, 29(5):434-442, 2002.

23. Sun J, Zhao Q and Rai SN. A Nonparametric Comparison of Tumour Incidences with Intermediate Lethality and Different Death Rates. In: Recent Advances in Statistical Methods, (Ed.) Y. P. Chaubey, World Scientific Publishing, London, 296-303, 2002.

22. Phipps S, Dunavant M, Garvie P, Lensing S and Rai SN. Acute Health-Related Quality of Life in Children Undergoing Stem Cell Transplant: I. Descriptive Outcomes. Bone Marrow Transplant, 29(5):425-434, 2002.

21. Rai SN, Bartlett S, Krewski D and Peterson J. The Use of Probabilistic Risk Assessment in Establishing Drinking Water Quality Objectives. Human and Ecological Risk Assessment, 8: 493-509, 2002.

20. Emam KEl, Benlarbi S, Goel N, Melo W, Lounis H and Rai SN. The optimal class-size for object-oriented software. IEEE Transactions on Software Engineering, 28(5):494-509, 2002.

19. Rai SN., Kovacevic, M.S. and Srivastava, D.K. Estimation in Hierarchical Linear Models using Pseudo Maximum Likelihood Method Far East Journal of Theoretical Statistics, 5(2): 205-221, 2001.

18. Sun J and Rai SN. Non-parametric Tests for the Comparison of Point Processes Based on Incomplete Data. Scandinavian Journal of Statistics, 28: 725-732, 2001.

17. Emam KEl, Benlarbi S, Goel N and Rai SN. The confounding effect of class size on the validity of object-oriented metrics. IEEE Transactions on Software Engineering, 27(7): 630-650, 2001.

16. Emam KEl, Benlarbi S, Goel N and Rai SN. Comparing Case-Based Reasoning Classifiers for Predicting High Risk Software Components. The Journal of Systems and Software, 55: 301-320, 2000.

15. Rai SN, Matthews DE and Krewski D. Mixed Scale Models for Survival/Sacrifice Experiments. The Canadian Journal of Statistics, 28: 65-80, 2000.

14. Benlarbi S, Emam KEl, Goel N and Rai SN. Thresholds for Object-Oriented Measures. Proceedings of the International Symposium on Software Reliability Engineering, pages 24-37, 2000.

13. Kovacevic MS and Rai SN. A Pseudo Maximum Likelihood Approach To Inference on Hierarchically Structured Data. Proceedings of Joints Statistical Meetings 1999, Section of Survey Research Methods, pages 605-610, 1999.

12. Krewski D, Rai SN, Zielinski J and Hopke PK. Characterization of Uncertainty and Variability Characterization in Residential Radon Cancer Risks. The Annals of the New York Academy of Sciences, 895:245-272, 1999.
11. Rai SN, Zielinski JM and Krewski D. Uncertainties in Estimates of Radon Lung Cancer Risks. Proceedings of Statistics Canada Symposium 99: Combining Data from Different Sources, pages 99-107, 1999.

10. Rai SN and Krewski, D. Uncertainty and Variability Analysis in Multiplicative Risk Models. Risk Analysis, 18:37-45, 1998.

9. Rai SN. On semi-Parametric Models in Occult Tumour Experiments. Biometrical Journal, 39:909-918, 1997.

8. Rai SN and Matthews DE. Discrete Scale Models for Survival/Sacrifice Experiments. Journal of the Royal Statistical Society Series C, 46:93-109, 1997.

7. Rai SN, Krewski D and Bartlett S. A General Framework for the Analysis of Uncertainty and Variability in Risk Assessment. Human and Ecological Risk Assessment, 2:972-989, 1996.

6. Bartlett S, Richardson GM, Krewski D, Rai, SN and Fyfe, M. Commentary: Characterizing Uncertainty in Risk Assessment – Conclusions Drawn from a Workshop. Human and Ecological Risk Assessment, 2:217-227, 1996.

5. Rai SN and Matthews DE. Analysis of Incomplete Data Using Stochastic Covariates. The Canadian Journal of Statistics, 23:29-42, 1995.

4. Rai SN, Abraham B and Peiris S. Analysis of Short Time Series with an Over-Dispersion Model. Communications in Statistics - Theory and Methods, 24:335-348, 1995.

3. Rai SN and Matthews, D.E. Improving the EM Algorithm. Biometrics, 49:587-591, 1993.

2. Sisodia BVS and Rai SN. On Estimation Procedures of Variance Subsequent to Preliminary Test of Significance. Microelectron Reliability, 31:1101-1104, 1991.

1. Sharma DD and Rai SN. Effect of Temperature and Relative Humidity on the Development and Survival of Various Stages of Acrocorcops Oramerella. Sn. Journal of Current Biosciences, 31:101-103, 1984.

88. Rai SN and Sun J. Types of Censoring In Time to Event Data. (Chapter XX). In: Everitt B and Melnick, E (Ed.), Encyclopedia of Quantitative Risk Assessment. Wiley and Sons. (pp. xx-xx), 2008 (In Press).