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Research Areas

Guy Brock, Ph.D.
Assistant Professor
guy.brock@louisville.edu
Research interests:
The areas of statistical genetics and the analysis of microarray data. Recent projects include developing methods for nonparametric linkage analysis in extended pedigrees, evaluating methods for handling selection bias in linkage studies, and missing value estimation in microarray data. Also interested in developing methods for handling proteomic data.

Somnath Datta, Ph.D.
Professor
somnath.datta@louisville.edu
Research interests:
Various topics in Statistics and Biostatistics such as Bioinformatics, Bootstrap Methods, Compound Decision Problems, Empirical Bayes Methods, Nonparametric Function Estimation, Statistical Genetics, Survival Data Analysis, Time Series Analysis, etc. Currently working on multistage data that are an important special case of multivariate survival or event time data. Also interested in nonparametric and semiparametric inference procedures for such multistage models. Interested in nonparametric inference procedures for marginal effects in clustered data, such as those that arise in longitudinal studies. In the area of Bioinformatics, working on developing novel statistical methods for gene expression and proteomic data.

Susmita Datta, Ph.D.
Associate Professor
susmita.datta@louisville.edu
Research interests:
Bioinformatics, Biostatistics, Statistical Issues in Population Biology, Statistical Genetics, Infectious Disease Modeling and Survival Analysis. Also involved in developing statistical methods for analyzing microarray data. Working on the problems of modeling gene expression profiles through partial least squares regression, validation of clustering algorithms for grouping genes and developing various statistical tools for detection of differential gene expression. Also actively interested in proteomic data (MALDI-TOF, SELDI) analysis to understand disease etiology (colon, lung cancer etc.), as well as collaborative research with interdisciplinary scientists from Biochemistry, Biology, Public Health and Computer science.

L. Jane Goldsmith, Ph.D.
Associate Professor
jane.goldsmith@louisville.edu
Research interests:
Primarily collaborative research in medicine and dentistry. Also interested in statistical methodology research relating to sample size, information theory, nonlinear models and inter-rater agreement.

Steven J. McCabe, M.D., M.Sc.
Director, Biostatistics - Decision Science Program
Assistant Professor
smccabe@kkahand.com
Research interests:
Clinical research as it relates to hand and upper extremity surgery. Also interested in measuring the results of treatment including the use of outcomes questionnaires and utility measurements. Interested in all aspects of the management of carpal tunnel syndrome. Currently developing an interest in cost-effectiveness analysis in upper extremity surgery.

John A. Myers, Ph.D.
Visiting Professor
john.myers@louisville.edu
Research interests:
Problems in health care economics and the impact of these problems on public policy and medical guidelines. Examining the theoretical foundations of cost-effectiveness analysis, including such issues as measuring the effectiveness of interventions that have an influence on two closely linked individuals, more precisely modeling quality adjusted life years gained over time and the role risk attitudes play in assessing the effectiveness of health care interventions. Another major area of study is investigating the position religiosity and spirituality have in the care of chronically ill patients and patients receiving end-of-life care. Other work includes examining HIV disease progression, modeling the transition from use of alcohol to dependence on alcohol, and the interrelationship of donors and recipients during organ transplantation.

Rudolph S. Parrish, Ph.D.
Professor and Chair
rudy.parrish@louisville.edu
Research interests:
Statistical methods in bioinformatics with applications to high-dimensional biology techniques, statistical computing, clinical trial design, group-sequential methods, linear and mixed-effects models, and modeling. Current activity is in evaluation of statistical methods for analysis of microarray data through simulation approaches.

Jae Keun Yoo (Peter)
Assistant Professor
peter.yoo@louisville.edu
Research interests:
Sufficient dimension reduction, Linear and Non-linear model, Survival analysis, Bioinformatics, Multivariate analysis


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