KY INBRE-funded Next Generation Sequencing Projects
Title |
Researcher |
Inst. |
Type |
Year |
|---|---|---|---|---|
Effects of Early-Life Antipsychotic Drug Administration on RNA expression |
Bardgett, Mark |
NKU |
Rat brain RNA-Seq; 32 samples. |
2020 |
The effect of the estrus cycle on microbiota composition and the Listeria Monocytogenes infectious process in murine models |
Pierce, Marcia |
EKU |
Mouse fecal microbiome 16S RNA-Seq ; 45 samples. |
2020 |
Transcriptome profiling of pancreatic cancer cells treated with novel Ras inhibitors |
+Clark, Geoffrey |
UofL |
Human RNA-Seq; 12 samples. |
2020 |
Single Cell Sequencing of Ocular Immune Cells in a Model of Uveitis Pre-and Post-Anti- IL-6 Treatment |
Donninger, Howard |
UofL |
Mouse ocular cells Sc-RNA-Seq; 2 samples. |
2020 |
Unveiling transcriptome changes in lymphatic cells from lymph fluid |
Hao, Hongying |
UofL |
Human lymph cells sc-RNA-Seq; 4 samples. |
2020 |
Transcriptome profiling of cancer associated fibroblasts |
Donninger, Howard |
UofL |
Human RNA-Seq; 9 samples. |
2019 |
Differential Expression of Unconventional Targets for Type 1 |
Shirwan, Haval |
UofL |
Mouse RNA-Seq; 24 samples. |
2019 |
Urine Microbiome of Persons with Pneumo coccal Pneumonia Using NGS- |
Wolf, Leslie |
UofL |
Human urine microbiome; 60 samples. |
2019 |
Sex differences in neural effects of prenatal cigarette smoke exposure |
Corbitt, Cynthia |
UofL |
Mouse RNA-Seq; 24 samples. |
2019 |
Differential Gene Expression in Checkpoint and S-Adenosyl Methionine Synthetase Mutants |
Strome, Erin |
NKU |
Yeast RNA-Seq; 24 samples. |
2019 |
Next Generation Sequencing to Reveal Novel Platinum Compound-Induced Cancer Cell Death Pathways |
Smith, Michael |
WKU |
Human RNA-Seq; 27 samples. |
2018 |
Transcriptional response to the loss of Shoc2 in zebrafish |
Galperin, Emilia |
UK |
Zebrafish RNA-Seq; 12 samples. |
2018 |
Differential Regulation of Zn Transporters Associated with Zn Hyperaccumulation |
Thompson, David |
NKU |
Squirrelfish RNA-Seq; 24 samples. |
2018 |
Whole Exome and T-cell Receptor Repertoire Sequencing in Immunotherapy-treated Cancer Patients |
Yaddanapudi, Kavitha |
UofL |
Human Amplicon Seq; 12 samples. |
2018 |
Identifying Gene Expression Differences in S-Adenosyl Methionine Synthetase Mutants |
Strome, Erin |
NKU |
Yeast RNA-Seq; 40 samples. |
2017 |
Identification of HNRNPA2B1-regulated miRNA targets in breast cancer cells |
Klinge, Carolyn |
UofL |
Human RNA-Seq; 12 samples. |
2017 |
PSAT1 Mediated Changes in Gene Expression in EGF-Stimulated Lung Cancer |
Clem, Brian |
UofL |
Human RNA-Seq; 18 samples. |
2017 |
Transcriptomic Analysis of Macrophages Persistently Infected by Arthrogenic Alphaviruses |
Sokoloski, Kevin |
UofL |
Human RNA-Seq; 6 samples. |
2017 |
Identifying Risks Associated with Antibiotic Resistant Bacteria in Louisville Environments |
Himes, Paul |
UofL |
Microbiome DNA-Seq; 10 samples. |
2017 |
Transcriptome Analysis of Novel Hepatitis C Vaccines in Human Dendritic Cells |
Mester, Joseph |
NKU |
Human RNA-Seq; 30 samples. |
2017 |
Transcriptomic response of nucleated red blood cells to lipopolysaccharid (LPS)challenge in Zebra finch (Taeniopygia guttata) > |
Ashley, Noah |
WKU |
Zebra finch RNA-Seq; 12 samples. |
2017 |
LncRNA-dependent mechanism of DNA/RNA-binding proteins. |
Ushida, Shizuka |
UofL |
RIP-Seq; 10 samples. |
2017 |
Isolation and gene expression profiling of successfully regenerating hindbrain. |
Gibbs, Kurt |
MST |
RNA-Seq; 6 samples. |
2017 |
PCBs and changes in the microbiome during pregnancy and lactation. |
Curran, Christine |
NKU |
16S RNA-Seq; 64 samples. |
2017 |
Role of iron-sulfur cluster proteins in diabetes: shifting metabolism one sugar at a time. |
Menze, Mike |
UofL |
RNA-Seq; 12 samples. |
2017 |
Investigating β-caryophyllene-induced alterations in transcriptome profiles related to Identifying novel targets of Iroquois transcription factors in the vertebrate pharynx. |
Frost, Chris |
UofL |
RNA-Seq 12 samples. |
2017 |
Identifying novel targets of Iroquois transcription factors in the vertebrate pharynx. |
|
NKU |
RNA-Seq;9 samples. |
2017 |
Characterization of Chemo-Resistant Breast Cancer Cells Using RNA-seq. |
Imbert-Fernandes, Joannis |
UofL |
RNA-Seq; DNA-Seq; 18 samples. |
2017 |
Molecular mechanism by which circadian clock regulates gene expression. |
Jacobshagen, Sigrid; |
WKU |
ChIP-Seq; 9 samples. |
2017 |
Identification of point mutations in the Pu27 family G-quadruplex sequences. |
Miller, Don |
UofL |
Amplicon-Seq; 25 samples. |
2017 |
Microbial Ecology of Antibiotic Resistance in Louisville Environments. |
Himes, Paul |
UofL |
16S RNA-Seq; 110 samples. |
2017 |
Genome-wide CRISPR-Cas9 Screen to Identify Pathways that Determine Response to AS1411. |
Bates, Paula |
UofL |
Amplicon-Seq; 15 samples |
2017 |
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Transcriptomics of the avian Iimmune response using RNA-seq. |
Ashley, Noah |
WKU |
RNA-Seq; 16 samples |
2016 |
Quantifying gene expression changes in Xenopus laevis spinal cord following crush injury. |
Gibbs, Kurt, |
Morehead State |
RNA-Seq, 12-18 samples |
2016 |
Whole genome CRISPR/Cas9 screen to identify genes required for survival of lung cancer cells on 3 dimensional ECM treated with cisplatin. |
Beverly, Levi/Siskind, Leah |
UofL |
Amplicon-Seq; 10 samples. |
2016 |
Metabolic inflexibility with obesity: Investigating molecular mechanisms that influence the metabolic health of women. |
|
WKU |
ChIP-Seq, 12 samples |
2016 |
Comparative gene expression associated with inflammation and endoplasmic reticulum stress in diabetic kidney. |
Pushpakuma, Sathnur/ Weber, Gregg |
UofL |
RNA-Seq, 12 samples |
2016 |
Role of tudor gene in small piRNA biogenesis in Drosophila Brain. |
Arkov, Alex |
Murray State |
miRNA-Seq, 6 samples. |
2016 |
Quantify differentially abundant RNA transcripts in mouse kidney tissue with chronic alcohol consumption. |
Merchant, Michael |
UofL |
RNA-Seq, 12 samples. |
2016 |
Determine transcriptome response to endoplasmic reticulum stress in rat oligodendrocyte precursor cells. |
Hetman, Michal |
UofL |
RNA-Seq, 12 samples |
2016 |
Impact of G-quadruplex forming oligonucleotides from c-MYC promoter (Pu27). |
Miller, Donald/ Rezzoug, Francine |
UofL |
RNA-Seq, 12 samples |
2016 |
Comparative gene expression analysis in melanocytes driven by tumor cell-derived exosomes. |
McMasters, Kelly/ Hao, Hongying |
UofL |
RNA-Seq, 9 samples |
2016 |
Identification of molecular of targets of natural compound which inhibits breast cancer stem cells. |
Damodaran, Chendil |
UofL |
RNA-Seq, 12 samples. |
2016 |
Novel Interferon-stimulated gene pathway. |
Chung, Donghoon |
UofL |
RNA-Seq, 6 samples. |
2016 |
Manipulation of PMN gene expression during Yersinia pestis infection. |
Lawrence, Matt |
UofL |
RNA-Seq, 12 samples. |
2016 |
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Variant detection of human respiratory syncytial virus |
Bill Severson, Department of Microbiology |
UofL |
WGS/variant |
2015 |
Comparison of SBKR-3 Single Cell vs. Cell Line SNP Detection Using AmpliSeqTM Cancer Hotspot Panel |
Lori Millner, Department of Pathology and Laboratory Medicine |
UofL |
Cancer Hotspot |
2015 |
Sequence and Variant Analysis of Pu27 Homologs using Amplicon Sequencing |
Don Miller, Department of Medicine - Oncology |
UofL |
Custom Amplicon |
2015 |
Analysis of Putative g-Quadruplex Forming Sequences Within the Mus musculus Papillomavirus |
Alfred Jensen, Department of Medicine - Oncology |
UofL |
Bioinformatics |
2015 |
Comparison of Methodologies for Differential Expression of a Mus musculus RNASeq Dataset Generated on the CeGeMM NextSeq-500 |
Alan Cheng, Department of Biochemistry and Molecular Biology |
UofL |
RNASeq |
2015 |
Analysis of g-Quadruplex Forming Sequences Within the Manatee Papillomavirus |
Alfred Jensen, Department of Medicine - Oncology |
UofL |
Bioinformatics |
2015 |
Gut microbiota of APCmin and CCR2XAPCmin mice |
Venkatakrishna Jala, Department of Microbiology |
UofL |
16s rRNA |
2015 |
Pu27 Treatment Analysis Using RNA-Seq |
Don Miller, Department of Medicine - Oncology |
UofL |
RNASeq |
2015 |
Analysis of g-Quadruplex Forming Sequences Across 9 Rodent Papillomavirus Genomes |
Joongho Joh, Department of Medicine - Oncology |
UofL |
Bioinformatics |
2015 |
RNASeq Analysis of human neutrophils infected with F. alocis |
Sylvia Uriatre |
UofL |
RNASeq |
2015 |
Bind-N-Seq Analysis of Zink Finger Proteins |
Moon-Soo Kim |
WKU |
Amplicon Sequencing |
2015 |
Analysis of g-Quadruplex Forming Sequences Within Manatee Papillomavirus Strains 1,3,4 |
Alfred Jenson |
UofL |
Bioinformatics |
2015 |
Transcriptome Study of Acinobacter baumanni ddrR Mutant vs WT cells |
Janelle Hare |
MSU |
RNASeq |
2015 |
Identification of host innate immune genes activated by pyrimidine depletion in cells |
Donghoon Chung |
UofL |
RNASeq |
2015 |
Transcriptome Assembly of Pelargonium X Hortorum |
David Schultz |
UofL |
RNASeq |
2015 |
RNASeq Analysis of Crystalline Sillica (CS) Promoting Lung Tumor Growth by Recruiting N2-Neutrophils |
Hari Bodduluri |
UofL |
RNASeq |
2015 |
Investigating the relationships between the various cellular compositions of ECTs and the tissue level activation of critical regulatory pathways relevant to myocardial function, remodeling, and angiogenesis |
Fei Yi |
UofL |
RNASeq |
2015 |
Immunomodulatory effects of Urolithin A on Macrophages |
Venkatakrishna Jala, Department of Microbiology |
UofL |
RNASeq |
2015 |
Gut microbiome analysis of colon cancer and IBD patients using an open reference |
Venkatakrishna Jala |
UofL |
16s rRNA |
2015 |
Pu27 Treatment Analysis Using RNA-Seq: A comparison of hg19 and hg38 using Ensembl Annotations |
Don Miller, Department of Medicine - Oncology |
UofL |
RNASeq |
2015 |
Identification of differentially expressed genes between two breast cancer cell lines: MDA231 and MDA231LN |
Jino Park |
UofL |
RNASeq |
2015 |
Hepatitis C variant detection, round II |
Michael Hughes, Department of Surgery - General |
UofL |
Variant |
2014 |
Ion AmpliSeqTM Comprehensive Cancer Panel Variant Detection |
Donald Miller, Department of Medicine - Oncology |
UofL |
CCP |
2014 |
Ion AmpliSeq TM Comprehensive Cancer Panel Variant Detection for Fanconi Anemia |
Alfred Jenson, Department of Medicine - Oncology |
UofL |
CCP |
2014 |
Role of PARP1 in Alternative Splicing |
Yvonne Fondufe-Mittendorf, Department of Cellular and Molecular Biology |
UK |
RNASeq |
2014 |
Mechanisms of soy glyceollin in brain |
Cynthia Corbitt, Department of Biology |
UofL |
RNASeq |
2014 |
Sex specific miRNA expression profiles in mice with left ventricular hypertrophy using pyrosequencing |
Rebekah Waikel, Department of Biology |
EKU |
miRNA |
2014 |
Transcriptional analysis of African green monkey cells with lentivirus treatment |
Emilia Galperin, Department of Cellular and Molecular Biology |
UK |
RNASeq |
2014 |
Gut microbiome analysis of colon cancer and IBD patients using a closed reference |
Venkatakrishna Jala, Department of Microbiology |
UofL |
16s rRNA |
2014 |
Legionella Variant Detection |
Yousef Abu-Kwaik, Department of Microbiology |
UofL |
Variant |
2013 |
Adenovirus Variant Detection |
Sam Zhou, Department of Surgery - Oncology |
UofL |
Variant |
2013 |
Hepatitis C variant detection |
Michael Hughes, Department of Surgery - General |
UofL |
Variant |
2013 |
Amplicon sequencing of equine encephalitis virus and SNPs detection |
Donghoon Chung, Department of Microbiology |
UofL |
WGS/Variant |
2013 |
De novo sequencing of Achebe bacteriophage |
Claire Rinehart, Department of Biology |
WKU |
WGS/Variant |
2013 |
De novo sequencing of Busterbird bacteriophage |
Claire Rinehart, Department of Biology |
WKU |
WGS/Variant |
2013 |
miRNA profiles of oral cancer cells after treatment with tobacco products |
Wolfgang Zacharias, Department of Medicine - Oncology |
UofL |
miRNA |
2013 |
Sex specific miRNA expression profiles in mice with Left Ventricular Hypertrophy |
Rebekah Waikel |
EKU |
miRNASeq |
2012 |
Transcriptome analysis of Acinetobacter baumannii |
Janelle Hare |
MoSU |
RNASeq |
2012 |
Growth Hormone Pathways in Zebrafish Auditory Hair Cell Regeneration using GH Antagonist |
Michael Smith |
WKU |
RNASeq |
2012 |
Using Next-generation Sequencing to Reveal the Target Genes of miR-21 and its Function in Acute Pancreatitis |
Yong Li |
UofL |
RNASeq |
2012 |
Exosome miRNA profiles as innovative biomarkers in melanoma patients |
Hongying Hao |
UofL |
miRNASeq |
2012 |
Gut microbiome analysis of colon cancer and IBD patients |
Venkatakrishna Jala |
UofL |
16s |
2012 |
To establish an RNA code regulated by hnRNPH in oligodendrocytes by mapping RNA protein interactions in vivo |
Franca Cambi |
UK |
RIP-Seq |
2012 |
The role of stress granule mRNA in adaptive stress responses of the murine kidney |
Michael Merchant, Department of Medicine - Renal |
UofL |
RNASeq |
2012 |
De Novo sequencing of Pseudomonas fluorescens |
Hazel Barton |
NKU |
De-novo |
2011 |
Sex specific miRNA expression profiles in mice with Left Ventricular Hypertrophy using pyrosequencing |
Rebekah Waikel |
EKU |
miRNA Seq |
2011 |
Next Generation Sequencing to Reveal Growth Hormone Pathways in Zebrafish Auditory Hair Cell Regeneration |
Michael Smith |
WKU |
RNASeq |
2011 |
Identification of axonal collateral sprouting-specific genes |
Jeffrey Petruska |
UofL |
RNASeq |
2011 |
Activity/stress increases acetylation of lysine 14 in histone H3 (H3K14ac) in olfactory sensory neurons |
Timothy McClintock |
UK |
CHiPSeq |
2011 |