KBRIN-funded Next Generation Sequencing Projects
Title | Researcher | Inst. | Type | Year |
|---|---|---|---|---|
LncRNA-dependent mechanism of DNA/RNA-binding proteins. | Ushida, Shizuka | UofL | RIP-Seq; 10 samples. | 2017 |
Isolation and gene expression profiling of successfully regenerating hindbrain. | Gibbs, Kurt | MST | RNA-Seq; 6 samples. | 2017 |
PCBs and changes in the microbiome during pregnancy and lactation. | Curran, Christine | NKU | 16S RNA-Seq; 64 samples. | 2017 |
Role of iron-sulfur cluster proteins in diabetes: shifting metabolism one sugar at a time. | Menze, Mike | UofL | RNA-Seq; 12 samples. | 2017 |
Investigating β-caryophyllene-induced alterations in transcriptome profiles related to Identifying novel targets of Iroquois transcription factors in the vertebrate pharynx. | Frost, Chris | UofL | RNA-Seq 12 samples. | 2017 |
Identifying novel targets of Iroquois transcription factors in the vertebrate pharynx. |
| NKU | RNA-Seq;9 samples. | 2017 |
Characterization of Chemo-Resistant Breast Cancer Cells Using RNA-seq. | Imbert-Fernandes, Joannis | UofL | RNA-Seq; DNA-Seq; 18 samples. | 2017 |
Molecular mechanism by which circadian clock regulates gene expression. | Jacobshagen, Sigrid; | WKU | ChIP-Seq; 9 samples. | 2017 |
Identification of point mutations in the Pu27 family G-quadruplex sequences. | Miller, Don | UofL | Amplicon-Seq; 25 samples. | 2017 |
Microbial Ecology of Antibiotic Resistance in Louisville Environments. | Himes, Paul | UofL | 16S RNA-Seq; 110 samples. | 2017 |
Genome-wide CRISPR-Cas9 Screen to Identify Pathways that Determine Response to AS1411. | Bates, Paula | UofL | Amplicon-Seq; 15 samples | 2017 |
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Transcriptomics of the avian Iimmune response using RNA-seq. | Ashley, Noah | WKU | RNA-Seq; 16 samples | 2016 |
Quantifying gene expression changes in Xenopus laevis spinal cord following crush injury. | Gibbs, Kurt, | Morehead State | RNA-Seq, 12-18 samples | 2016 |
Whole genome CRISPR/Cas9 screen to identify genes required for survival of lung cancer cells on 3 dimensional ECM treated with cisplatin. | Beverly, Levi/Siskind, Leah | UofL | Amplicon-Seq; 10 samples. | 2016 |
Metabolic inflexibility with obesity: Investigating molecular mechanisms that influence the metabolic health of women. |
| WKU | ChIP-Seq, 12 samples | 2016 |
Comparative gene expression associated with inflammation and endoplasmic reticulum stress in diabetic kidney. | Pushpakuma, Sathnur/ Weber, Gregg | UofL | RNA-Seq, 12 samples | 2016 |
Role of tudor gene in small piRNA biogenesis in Drosophila Brain. | Arkov, Alex | Murray State | miRNA-Seq, 6 samples. | 2016 |
Quantify differentially abundant RNA transcripts in mouse kidney tissue with chronic alcohol consumption. | Merchant, Michael | UofL | RNA-Seq, 12 samples. | 2016 |
Determine transcriptome response to endoplasmic reticulum stress in rat oligodendrocyte precursor cells. | Hetman, Michal | UofL | RNA-Seq, 12 samples | 2016 |
Impact of G-quadruplex forming oligonucleotides from c-MYC promoter (Pu27). | Miller, Donald/ Rezzoug, Francine | UofL | RNA-Seq, 12 samples | 2016 |
Comparative gene expression analysis in melanocytes driven by tumor cell-derived exosomes. | McMasters, Kelly/ Hao, Hongying | UofL | RNA-Seq, 9 samples | 2016 |
Identification of molecular of targets of natural compound which inhibits breast cancer stem cells. | Damodaran, Chendil | UofL | RNA-Seq, 12 samples. | 2016 |
Novel Interferon-stimulated gene pathway. | Chung, Donghoon | UofL | RNA-Seq, 6 samples. | 2016 |
Manipulation of PMN gene expression during Yersinia pestis infection. | Lawrence, Matt | UofL | RNA-Seq, 12 samples. | 2016 |
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Variant detection of human respiratory syncytial virus | Bill Severson, Department of Microbiology | UofL | WGS/variant | 2015 |
Comparison of SBKR-3 Single Cell vs. Cell Line SNP Detection Using AmpliSeqTM Cancer Hotspot Panel | Lori Millner, Department of Pathology and Laboratory Medicine | UofL | Cancer Hotspot | 2015 |
Sequence and Variant Analysis of Pu27 Homologs using Amplicon Sequencing | Don Miller, Department of Medicine - Oncology | UofL | Custom Amplicon | 2015 |
Analysis of Putative g-Quadruplex Forming Sequences Within the Mus musculus Papillomavirus | Alfred Jensen, Department of Medicine - Oncology | UofL | Bioinformatics | 2015 |
Comparison of Methodologies for Differential Expression of a Mus musculus RNASeq Dataset Generated on the CeGeMM NextSeq-500 | Alan Cheng, Department of Biochemistry and Molecular Biology | UofL | RNASeq | 2015 |
Analysis of g-Quadruplex Forming Sequences Within the Manatee Papillomavirus | Alfred Jensen, Department of Medicine - Oncology | UofL | Bioinformatics | 2015 |
Gut microbiota of APCmin and CCR2XAPCmin mice | Venkatakrishna Jala, Department of Microbiology | UofL | 16s rRNA | 2015 |
Pu27 Treatment Analysis Using RNA-Seq | Don Miller, Department of Medicine - Oncology | UofL | RNASeq | 2015 |
Analysis of g-Quadruplex Forming Sequences Across 9 Rodent Papillomavirus Genomes | Joongho Joh, Department of Medicine - Oncology | UofL | Bioinformatics | 2015 |
RNASeq Analysis of human neutrophils infected with F. alocis | Sylvia Uriatre | UofL | RNASeq | 2015 |
Bind-N-Seq Analysis of Zink Finger Proteins | Moon-Soo Kim | WKU | Amplicon Sequencing | 2015 |
Analysis of g-Quadruplex Forming Sequences Within Manatee Papillomavirus Strains 1,3,4 | Alfred Jenson | UofL | Bioinformatics | 2015 |
Transcriptome Study of Acinobacter baumanni ddrR Mutant vs WT cells | Janelle Hare | MSU | RNASeq | 2015 |
Identification of host innate immune genes activated by pyrimidine depletion in cells | Donghoon Chung | UofL | RNASeq | 2015 |
Transcriptome Assembly of Pelargonium X Hortorum | David Schultz | UofL | RNASeq | 2015 |
RNASeq Analysis of Crystalline Sillica (CS) Promoting Lung Tumor Growth by Recruiting N2-Neutrophils | Hari Bodduluri | UofL | RNASeq | 2015 |
Investigating the relationships between the various cellular compositions of ECTs and the tissue level activation of critical regulatory pathways relevant to myocardial function, remodeling, and angiogenesis | Fei Yi | UofL | RNASeq | 2015 |
Immunomodulatory effects of Urolithin A on Macrophages | Venkatakrishna Jala, Department of Microbiology | UofL | RNASeq | 2015 |
Gut microbiome analysis of colon cancer and IBD patients using an open reference | Venkatakrishna Jala | UofL | 16s rRNA | 2015 |
Pu27 Treatment Analysis Using RNA-Seq: A comparison of hg19 and hg38 using Ensembl Annotations | Don Miller, Department of Medicine - Oncology | UofL | RNASeq | 2015 |
Identification of differentially expressed genes between two breast cancer cell lines: MDA231 and MDA231LN | Jino Park | UofL | RNASeq | 2015 |
Hepatitis C variant detection, round II | Michael Hughes, Department of Surgery - General | UofL | Variant | 2014 |
Ion AmpliSeqTM Comprehensive Cancer Panel Variant Detection | Donald Miller, Department of Medicine - Oncology | UofL | CCP | 2014 |
Ion AmpliSeq TM Comprehensive Cancer Panel Variant Detection for Fanconi Anemia | Alfred Jenson, Department of Medicine - Oncology | UofL | CCP | 2014 |
Role of PARP1 in Alternative Splicing | Yvonne Fondufe-Mittendorf, Department of Cellular and Molecular Biology | UK | RNASeq | 2014 |
Mechanisms of soy glyceollin in brain | Cynthia Corbitt, Department of Biology | UofL | RNASeq | 2014 |
Sex specific miRNA expression profiles in mice with left ventricular hypertrophy using pyrosequencing | Rebekah Waikel, Department of Biology | EKU | miRNA | 2014 |
Transcriptional analysis of African green monkey cells with lentivirus treatment | Emilia Galperin, Department of Cellular and Molecular Biology | UK | RNASeq | 2014 |
Gut microbiome analysis of colon cancer and IBD patients using a closed reference | Venkatakrishna Jala, Department of Microbiology | UofL | 16s rRNA | 2014 |
Legionella Variant Detection | Yousef Abu-Kwaik, Department of Microbiology | UofL | Variant | 2013 |
Adenovirus Variant Detection | Sam Zhou, Department of Surgery - Oncology | UofL | Variant | 2013 |
Hepatitis C variant detection | Michael Hughes, Department of Surgery - General | UofL | Variant | 2013 |
Amplicon sequencing of equine encephalitis virus and SNPs detection | Donghoon Chung, Department of Microbiology | UofL | WGS/Variant | 2013 |
De novo sequencing of Achebe bacteriophage | Claire Rinehart, Department of Biology | WKU | WGS/Variant | 2013 |
De novo sequencing of Busterbird bacteriophage | Claire Rinehart, Department of Biology | WKU | WGS/Variant | 2013 |
miRNA profiles of oral cancer cells after treatment with tobacco products | Wolfgang Zacharias, Department of Medicine - Oncology | UofL | miRNA | 2013 |
Sex specific miRNA expression profiles in mice with Left Ventricular Hypertrophy | Rebekah Waikel | EKU | miRNASeq | 2012 |
Transcriptome analysis of Acinetobacter baumannii | Janelle Hare | MoSU | RNASeq | 2012 |
Growth Hormone Pathways in Zebrafish Auditory Hair Cell Regeneration using GH Antagonist | Michael Smith | WKU | RNASeq | 2012 |
Using Next-generation Sequencing to Reveal the Target Genes of miR-21 and its Function in Acute Pancreatitis | Yong Li | UofL | RNASeq | 2012 |
Exosome miRNA profiles as innovative biomarkers in melanoma patients | Hongying Hao | UofL | miRNASeq | 2012 |
Gut microbiome analysis of colon cancer and IBD patients | Venkatakrishna Jala | UofL | 16s | 2012 |
To establish an RNA code regulated by hnRNPH in oligodendrocytes by mapping RNA protein interactions in vivo | Franca Cambi | UK | RIP-Seq | 2012 |
The role of stress granule mRNA in adaptive stress responses of the murine kidney | Michael Merchant, Department of Medicine - Renal | UofL | RNASeq | 2012 |
De Novo sequencing of Pseudomonas fluorescens | Hazel Barton | NKU | De-novo | 2011 |
Sex specific miRNA expression profiles in mice with Left Ventricular Hypertrophy using pyrosequencing | Rebekah Waikel | EKU | miRNA Seq | 2011 |
Next Generation Sequencing to Reveal Growth Hormone Pathways in Zebrafish Auditory Hair Cell Regeneration | Michael Smith | WKU | RNASeq | 2011 |
Identification of axonal collateral sprouting-specific genes | Jeffrey Petruska | UofL | RNASeq | 2011 |
Activity/stress increases acetylation of lysine 14 in histone H3 (H3K14ac) in olfactory sensory neurons | Timothy McClintock | UK | CHiPSeq | 2011 |