Recent Publications (selected examples)

2013. Stem Cells. (in press).

Zafir A, Readnower R, Long BW, McCracken J, Aird A, Alvarez A, Cummins TD, Li Q, Hill BG, Bhatnagar A, Prabhu SD, Bolli R, Jones SP. Protein O-GlcNAcylation is a novel cytoprotective signal in cardiac stem cells. 2013. Stem Cells. (in press).

2013. Biochem J. (in press).

Salabei JK, Cummins TD, Singh M, Jones SP, Bhatnagar A, Hill BG. PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress. 2013. Biochem J. (in press).

2013. Cell Metab. 17: 303-310.

Li MD, Ruan HB, Hughes ME, Lee JS, Singh JP, Jones SP, Nitabach MN, Yang X. O-GlcNAc signaling entrains the circadian clock by inhibiting BMAL1/CLOCK ubiquitination. 2013. Cell Metab. 17: 303-310.

2013. PLoS One. 8:e53951.

Wang J, Xu J, Wang Q, Brainard RE, Watson LJ, Jones SP, Epstein PN. Reduced cardiac fructose 2,6-bisphosphate increases hypertrophy and decreases glycolysis following aortic constriction. PLoS One. 2013. 8:e53951.

2012. Physiol Genomics. 44: 1208-1213.

Readnower RD, Brainard RE, Hill BG, Jones SP. Standardized Bioenergetic Profiling of Adult Mouse Cardiomyocytes. 2012. Physiol Genomics. 44: 1208-1213.

2012. PLoS One. 7: e41178.

Guo Y, Tukaye DN, Wu WJ, Zhu X, Book M, Tan W, Jones SP, Rokosh G, Narumiya S, Li Q, Bolli R. The COX-2/PGI2 receptor axis plays an obligatory role in mediating the cardioprotection conferred by the late phase of ischemic preconditioning. 2012. PLoS One. 7: 341178.

2012. Am J Physiol Heart Circ Physiol. 302: H2122-H2130.

Facundo HT, Brainard RE, Watson LJ, Ngoh GA, Hamid T, Prabhu SD, Jones SP. O-GlcNAc signaling is essential for NFAT-mediated transcriptional reprogramming during cardiomyocyte hypertrophy. Am J Physiol Heart Circ Physiol. 2012. 302: H2122-H2130. Podcast is here: (http://ajpheart.podbean.com/2012/04/24/o-glcnac-signaling-during-hypertrophy/).

2011. Am J Physiol Heart Circ Physiol. 301: H2073-H2080.

Wang J, Wang Q, Watson LJ, Jones SP, Epstein PN. Cardiac overexpression of 8-oxoguanine DNA glycosylase 1 protects mitochondrial DNA and reduces cardiac fibrosis following transaortic constriction. 2011. Am J Physiol Heart Circ Physiol. 301: H2073-H2080.

2011. Chem Biol Interact. 191: 288-295.

Sansbury BE, Jones SP, Riggs DW, Darley-Usmar VM, Hill BG. Bioenergetic function in cardiovascular cells: The importance of the reserve capacity and its biological regulation. 2011. Chem Biol Interact. 191: 288-295.

2011. Biochem J. 435: 519–528.

Sansbury BE, Riggs DW, Brainard RE, Salabei JK, Jones SP, Hill BG. Responses of hypertrophied myocytes to reactive species: implications for glycolysis and electrophile metabolism. 2011. Biochem J. 435: 519–528.

2011. Amino Acids. 40: 895-911.

Ngoh GA, Watson LJ, Facundo HT, Jones SP. Augmented O-GlcNAc signaling attenuates oxidative stress and calcium overload in cardiomyocytes. 2011. Amino Acids. 40: 895-911.

2010. Proc Natl Acad Sci USA. 107: 17797-17802.

Watson LJ, Facundo HT, Ngoh GA, Ameen M, Brainard RE, Lemma KM, Long BW, Prabhu SD, Xuan YT, Jones SP. O-linked β-N-acetylglucosamine transferase is indispensable in the failing heart. 2010. Proc Natl Acad Sci USA. 107: 17797-17802.

2010. Circulation Research. 107: 171-185.

Ngoh GA, Facundo HT, Zafir A, Jones SP. O-GlcNAc Signaling in the Cardiovascular System. 2010. Circulation Research. 107: 171-185.

2009. Am J Physiol Heart Circ Physiol. 297:H1711-9.

Ngoh GA, Hamid T, Prabhu SD, Jones SP. O-GlcNAc Signaling Attenuates ER Stress-Induced Cardiomyocyte Death. 2009. Am J Physiol Heart Circ Physiol. 297: H1711-9.

2009. Circulation Research. 104: 41-49.

Ngoh GA, Facundo HT, Hamid T, Dillmann W, Zachara NE, Jones SP. Unique Hexosaminidase Reduces Metabolic Survival Signal and Sensitizes Cardiac Myocytes to Hypoxia-Reoxygenation Injury. 2009. Circulation Research. 104: 41-49. **See associated editorial on page 7**

2008. Journal of Molecular and Cellular Cardiology. 45: 313-325.

Ngoh GA, Watson LJ, Facundo HT, Dillmann W, Jones SP. Noncanonical glycosyltransferase modulates post-hypoxic cardiac myocyte death and mitochondrial permeability transition. 2008. J Mol Cell Cardiol. 45: 313-325.

2008. Circulation. 117: 1172-1182.

Jones SP, Zachara NE, Ngoh GA, Hill BG, Teshima Y, Bhatnagar A, Hart GW, Marban E. Cardioprotection by N-acetylglucosamine linkage to cellular proteins. 2008. Circulation. 117: 1172-1182.