Research/Technology

A newly FDA-approved treatment for patients with advanced or inoperable melanoma who are no longer responding to other drugs is now available to patients at the University of Louisville’s James Graham Brown Cancer Center, a part of KentuckyOne Health. As a site for Keytruda’s research clinical trial, the cancer center is the first in Kentucky to offer the drug now that it is approved.
Top executive visit the Cardiovascular Innovation Institute

May 25, 2017 - UofL Hosts Fortune 500 Executives for Innovative Partnership Program
Nearly 20 top executives from some of the world’s largest companies visited the Cardiovascular Innovation Institute, Micro/Nano Technology Center, FirstBuild, and the Additive Manufacturing Competency Center to learn more about the emerging manufacturing technologies and strategies being developed in Louisville and on UofL’s Campuses.

UofL's School of Dentistry building

February 27, 2017 - UofL's School of Dentistry boasts top 15 national ranking in research dollars.
Thanks to a growing research enterprise, the University of Louisville School of Dentistry ranks 13th nationally in the National Institute of Dental and Craniofacial Research funding for 2016 — a jump from 17th in the previous year. “The UofL School of Dentistry is punching above its weight in securing National Institutes of Health research grants. This is an amazing achievement and a reflection of the tireless efforts of the talented research faculty,” said Dean T. Gerard Bradley, BDS, MS, DrMedDent.

UofL students work with 3-D printed prototypes

November 29, 2016 - UofL student startups pitch 3-D printed prototypes
Students in the University of Louisville’s new 3-D Printing Business Incubator spent the past semester designing and prototyping new products. “We are excited to have a hundred design engineers leverage disruptive 3-D printing technologies to create business with new products for biomedical, industrial, transportation and consumer sectors,” said professor Sundar Atre, Endowed Chair of Manufacturing and Materials, who launched the incubator. “What they have accomplished this semester is truly extraordinary.” More...

Dr. Emma Birks

November 16, 2016 - UofL research shows heart failure patients recover function with drug therapy and LVAD
A new study, led by Emma J. Birks, MBBS, PhD, professor at the University of Louisville School of Medicine, is showing that an artificial heart assist device along with medications, may actually help heal the heart, avoiding the need for a heart transplant and allowing for the removal of the device.

Dr. Aaron McGee

November 14, 2016 - UofL researcher to study methods to restore depth perception thanks to Disney award from RPB
Aaron W. McGee, PhD, assistant professor at the University of Louisville School of Medicine, has received the Disney Award for Amblyopia Research in the amount of $100,000 from Research to Prevent Blindness. McGee will use the award to investigate approaches for improving recovery from amblyopia, or “lazy eye.” The grant is offered to exceptional ophthalmic scientists – MDs or PhDs – with research pursuits of potential significance and promise. McGee is one of two scientists to receive the award in 2016.

Dr. Craig McClain

September 14, 2016 - UofL Researchers Take Lead Role in Exploring Liver Disease
Craig McClain, MD, UofL’s associate vice president for health affairs/research, is the principal investigator and head of a team that has received a Centers of Biomedical Research Excellence (COBRE) grant from the National Institutes of Health to explore diseases of the liver — hepatobiology and toxicology. Video...

Dr. Luz Huntington-Moskos

August 30, 2016 - UofL research shows more awareness needed on home environmental exposures that cause lung cancer
A University of Louisville School of Nursing researcher has found that the presence of children in the home did not motivate parents to test and mitigate for radon and secondhand tobacco smoke, both of which cause lung cancer. The findings highlight a need to raise awareness on these exposure risks and their long-term impact on children. Luz Huntington-Moskos, PhD, RN, CPN, UofL School of Nursing assistant professor, recently published the findings in the journal Public Health Nursing. More...

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July 22, 2016 - UofL ranked among top 100 universities in the world for U.S. patents granted
The University of Louisville is among the top 100 universities in the world that were granted U.S. utility patents for 2015. UofL ranked in a five-way tie for No. 97 with 25 patents in fiscal year 2015. “Belonging to this elite list is yet another affirmation that UofL has made great strides in the innovation arena in the last several years,” said Eugene Krentsel, associate vice president for research and innovation. More...

UofL NIH Designated Alcohol Research Center

July 20, 2016 - UofL opens NIH-designated Alcohol Research Center
Alcohol abuse exacts a major toll on health and health costs in the United States and is the 3rd leading preventable cause of death. Researchers at the University of Louisville have received a nearly $8 million grant from the NIH that designates them as an NIAAA Alcohol Research Center. The UofL Center is one of only 20 in the nation. It’s funding score for the grant was the best in the nation, and it is the only center with a nutrition focus. More...

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July 10, 2016 - UofL Human Subjects Protection Program earns reaccreditation
Research involving human subjects at the University of Louisville continues to follow the most stringent ethical and professional guidelines in existence, as evidenced by the UofL Human Subjects Protection Program earning reaccreditation by the Association for the Accreditation of Human Research Protection Programs. The UofL Human Subjects Protection Program Office (HSPPO) was awarded full accreditation for the maximum period allowed, five years. The HSPPO was the first such program in Kentucky accredited by the association when it received its original accreditation in 2005.

Drs. Kaplan, Steinbach-Rankins, Ramasubramanian

June 28, 2016 - Knights Templar Eye Foundation, Inc. grant supports UofL research for improved retinoblastoma treatment UofL researchers Aparna Ramasubramanian, M.D., and Jill Steinbach-Rankins, Ph.D., have received a grant from the Knights Templar Eye Foundation, Inc., to support their work in developing an improved chemotherapy treatment for retinoblastoma. Ramasubramanian, a pediatric ophthalmologist and ocular oncologist, and Steinbach-Rankins, a professor of bioengineering at the UofL J.B. Speed School of Engineering, are developing nanoparticles that will encapsulate the drug melphalan for use in intravitreal injections in the treatment of retinoblastoma. More...

Dr. Armon Perry

June 22, 2016 - UofL social work team receives $4.9 million to bridge family gaps
The University of Louisville will use a $4.9 million federal grant to help fathers who do not have custody of their children become more engaged parents and forge meaningful relationships with their families. The five-year 4 Your Child project, funded by the U.S. Department of Health and Human Services’ Administration for Children and Families, is led by a Kent School of Social Work team headed by Armon Perry, an associate professor who researches fathers’ involvement with children. More...

6 yr old with robohand

June 8, 2016 - UofL engineering students help child with ‘robohand’
Gina Bertocci, professor of bioengineering in the University of Louisville’s JB Speed School of Engineering, had the opportunity to help a 6-year-old boy with a ‘robo hand’ as well as teach her students the applications of doing the work that would help the child with his disability. view video View Video

David A. Scott, Ph.D.

May 31, 2016 - Dental researchers give us another reason to kick the habit
University of Louisville School of Dentistry researcher David A. Scott, PhD, explores how cigarettes lead to colonization of bacteria in the body. Scott and his research team have identified how tobacco smoke, composed of thousands of chemical components, is an environmental stressor and promotes bacteria colonization and immune invasion. More...

Angelique Johnson

May 19, 2016 - UofL working to create ‘next generation’ of women and minority researchers/mentors
Of the researchers who receive small business innovation grants from the federal government, just 10 percent are minorities and 6 percent are women. According to Angelique Johnson, an African American female researcher who received one of those grants for a flexible cochlear implant that could help deaf people hear, being a minority can be a hurdle for obtaining private investments. More...

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Mar 27, 2016 - Conn Center harnesses humidity to make clean fuels
The University of Louisville Conn Center for Renewable Energy Research has shown that solar energy can create clean hydrogen fuel by converting water vapor from the air. The journal Energy and Environmental Science recently published “Solar hydrogen production from seawater vapor electrolysis” by Conn Center researchers Sudesh Kumari, R. Turner White, Bijandra Kumar, and Joshua Spurgeon. More...

UofL School of Dentistry Researchers

Feb 26, 2016 - Researchers find association between oral bacteria and esophageal cancer
University of Louisville School of Dentistry researchers have found a bacterial species responsible for gum disease, Porphyromonas gingivalis, is present in 61 percent of patients with esophageal squamous cell carcinoma (ESCC). More...

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Feb 22, 2016 - Micro-fabrication for Cochlear Implants
Dr. Angelique Johnson and the UofL MNTC are the feature of a new NBC LEARN video as part of their popular “Science of Innovation” series. The video is about how her Louisville-based company uses advanced manufacturing to fabricate cochlear implants in the Cardinal cleanroom.view video View Video

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Dec 11, 2015 - UofL students create “bionic” hand for 6-year-old boy video
Dr. Gina Bertocci and her bioenginnering students changed the life of a 6-year old boy, who was born without a right hand, by creating 3-D generated hands.  view video View Video

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Dec 2, 2015 - UofL scientists identify a critical pathway to improve muscle repair
Researchers at UofL have discovered a mechanism involved in skeletal muscle repair that may enable clinicians to boost the effectiveness of adult stem cell therapies for diseases such as muscular dystrophy. Ashok Kumar, Ph.D., and Sajedah M. Hindi, Ph.D., believe their research ultimately will lead to improved treatments for muscle wasting diseases such as muscular dystrophy, amyotrophic lateral sclerosis (ALS), cancer cachexia, diabetes, heart disease and others. More...

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Nov 19, 2015 - Orthopaedic Bioengineering Research
Michael Voor in the Dept. of Orthopaedic Surgery discusses his multi-disciplinary research of broken hips and looks into devices that may be able to help. view video View Video

 

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Nov 16, 2015 - Grant Awards Up 25 Percent
UofL faculty submitted a record number of research proposals last fiscal year, resulting in a big increase in the number of grant awards. In FY ’15, UofL faculty posted 1,357 proposals, which secured $136.8 million in grant awards, a 25 percent increase in awards over FY’14. More...

Research Lab

Nov. 9, 2015 - UofL Reaps Big Dividends From Research Investments
The University of Louisville’s relatively small investments in new research ideas and projects has resulted in an average return on investment of 1,777 percent. Since 2000, UofL has spent $11 million in seed money for faculty-led research projects. Faculty in turn used that money to secure another $208 million in funding from outside sources like the National Institutes of Health or private investors. More...

Cancer therapy improvements, a tumor infiltrated with CD8+T cells

Oct 20, 2015 - UofL Researchers Awarded Patents
Technologies to improve bone grafts and cancer immunotherapies, protect lung tissue during radiation treatment, reverse neurological damage and improve recovery from spinal cord injury are among the patents issued to the University of Louisville Research Foundation recently. Two of the inventions have been licensed and are in the process of making their way into the health-care system to improve the lives of patients. More...

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Oct 1, 2015 - UofL Micro Nano Technology Center
The Micro/Nano Technology Center (MNTC) is utilized for both research and instructional purposes. The facility provides a state-of-the-art 10,000 ft2 cleanroom for teaching both fundamental and current fabrication techniques to manufacture integrated circuits (ICs), discrete microelectronic devices, microelectromechanical systems (MEMS), sensors and actuators and various electro-optic devices. The center also serves as an appropriate setting for technology transfer of information and projects. view video View Video

The CREAM Lab

July 6, 2015 - New Chemistry Instrument Vastly Expands Research Capabilities
The College of Arts & Sciences’ Center for Regulatory, Environmental and Analytical Metabolomics (CREAM) just installed a cutting edge instrument that will be used by researchers in the departments of Chemistry, Biology, Bioengineering, and Biomedical Sciences, as well as those from other universities around the country. The instrument was funded with a $600,000 National Institute of Health award given to Dr. Xiang Zhang. It will primarily be used for biomedical studies to understand disease mechanisms at the molecular level – with a focus on liver disease, cardiovascular disease, lupus, and cancer. More...

The main UofL Entrance

June 24, 2015 - UofL earns designation for commitment to economic engagement
UofL has earned recognition from the Washington, D.C.-based Association of Public and Land-grant Universities for its strong commitment to economic engagement. The APLU on June 24 named UofL and 17 other public universities to its 2015 class of “Innovation & Economic Prosperity Universities.” The designation acknowledges universities working with public and private sector partners to support economic development through innovation and entrepreneurship, technology transfer, workforce development and community development. More...

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May 29, 2015 - UofL part of first successful study of virus attack on cancer
It’s a new weapon in the arsenal of cancer fighting treatments: utilizing genetically modified viruses to invade cancer cells and destroy them from the inside. University of Louisville researcher Jason Chesney, M.D., Ph.D., deputy director of the James Graham Brown Cancer Center (JGBCC), and a team of international scientists found that stage IIIb to IV melanoma patients treated with a modified cold sore (herpes) virus had improved survival. More...

Inscope - School of Business Students

May 11, 2015 - Inscope wins global business plan contest
A University of Louisville College of Business student team marketing a wireless laryngoscope won the top prize Saturday at Global Venture Labs Investment competition in Austin, Texas. Inscope Medical Solutions team members Maggie Galloway, Mary Nan Mallory, Adam Casson and Will Coburn earned winnings valued at $75,000. That total includes a $25,000 cash prize, $25,000 incubator package and consulting time with the director of Jon Burmlay Texas Venture Labs. view video View Video

Haribabu Bodduluri

April 29, 2015 - University of Louisville researchers detail role of silica and lung cancer
Researchers at UofL have detailed a critical connection associated with a major environmental cause of silicosis and a form of lung cancer. Their study is reported in the April 29 issue of Nature Communications. Haribabu Bodduluri, PhD, professor of microbiology and immunology and a researcher in the James Graham Brown Cancer Center, and his team made the crucial connection between exposure to inhaled silica and rapid progression of lung cancers. This study also outlines the critical role of the inflammatory mediator LTB4 and its receptor BLT1 in promoting silica mediated lung tumor growth. More...

Paula Bates

April 23, 2015 - UofL awarded $3 million to speed technologies to market
UofL announced April 22 that a grant from the National Institutes of Health will combine with matching funds from the university to create a new $6.1 million initiative to commercialize discoveries made by UofL researchers. “This award illustrates the success UofL is witnessing in its mission to become a premiere metropolitan research university,” said William M. Pierce Jr., executive vice president for research and innovation. “We know it is not enough only to make great discoveries; we must find ways to bring those discoveries to the marketplace where they will benefit the people of our city, state and beyond. This grant provides significant support to do so.” view video View Video

Inscope - School of Business Students

April 18, 2015 - Inscope finishes second in Rice contest
Inscope, a University of Louisville College of Business graduate student team marketing a wireless laryngoscope, won second place in the Rice Business Plan Competition April 16-18 in Houston. More...

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April 3, 2015 - UofL start-up sets sights on boosting solar cell technology
A University of Louisville engineering professor is leading a team now that's developed a new approach that experts think could leapfrog existing technology and make waves in the multibillion-dollar global solar market. "The industry is very hungry for a solution," said Thad Druffel, theme leader for solar manufacturing at U of L's Conn Center for Renewable Energy Research and co-founder of a start-up, Bert Thin Films LLC. More... Courier-Journal, Grace Schneider

Barbara Polivka

March 31, 2015 - Not just for children: UofL researchers to examine asthma triggers in older adults
Although often considered a childhood health problem, asthma can cause serious illness for people age 60 and older, and little is known about the triggers of asthma in seniors. Understanding the personal and environmental influences of asthma in older adults is the focus of a $2.3 million National Institute on Aging grant awarded to Barbara Polivka, PhD, Shirley B. Powers Endowed Chair in Nursing, UofL School of Nursing, and her interdisciplinary team. view video View Video

Tanya Wiese

Jan 28, 2015 - UofL sole site in Kentucky testing investigational device for emphysema
UofL has launched a research trial to study an investigational medical device designed to aid patients with emphysema by shutting off the diseased part of the lung. UofL is the only site in Kentucky among 14 nationwide testing the device. More...

Brown Cancer Center

Dec 23, 2014 - UofL cancer researchers discover gene mutation's role
Researchers at the University of Louisville’s James Graham Brown Cancer Center have identified for the first time mutations that destabilize a DNA structure that turns a gene off. These mutations occur at four specific sites in what is known as the “hTERT promoter” in more than 75 percent of glioblastomas and melanomas. More...

3D printer

Dec 9, 2014 - Earth 2050 3D Printing
The "Xploration Earth 2050" program included a segment that highlights the 3D child's heart model that was designed by UofL's Rapid Prototying Center. View the Video

James McGaugh

Dec 2, 2014 - Scientist who links emotion, memory wins psychology award
A brain scientist who helped explain how our emotions affect what we learn and remember has won the 2015 University of Louisville Grawemeyer Award for Psychology. More...

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Nov. 21, 2014 - Childhood cancer research grant awarded to UofL
The St. Baldrick’s Foundation, a volunteer-driven and donor-centered charity dedicated to raising money for childhood cancer research, has awarded a one-year, $50,000 grant to the University of Louisville (UofL). This grant is one of 40 infrastructure grants awarded as part of the foundation’s fall grant cycle, totaling more than $2.5 million and surpassing last year’s total awarded during this same period. More...

Judith Danovitch

Nov. 20, 2014 - Powerful force: Study shows young children strongly favor familiar characters
Parents shopping for coveted holiday toys know well the pull that familiar characters in cartoons, movies or ads exert on purchasing. A recent study shows that even young children are highly susceptible to the allure of favorite characters when it comes to choosing products. More...

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Oct. 16, 2014 - Next generation: Scientist will preview space telescope
An astronomer on the team developing the scientific successor to the Hubble Space Telescope spoke about the complex project and what it may yield during an Oct. 16 lecture at the University of Louisville. More...

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Oct. 14, 2014 - UofL alcohol researcher to gave prestigious lecture
Craig J. McClain, MD, UofL associate vice president for health affairs/research and a prominent alcohol researcher, delivered the 19th Annual Mark Keller Honorary Lecture on Tuesday, Oct. 14, at the National Institutes of Health. More...

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Sept. 19, 2014 - Brown Cancer Center first in state to provide new melanoma drug
A newly FDA-approved treatment for patients with advanced or inoperable melanoma who are no longer responding to other drugs is now available to patients at the University of Louisville’s James Graham Brown Cancer Center, a part of KentuckyOne Health. As a site for Keytruda’s research clinical trial, the cancer center is the first in Kentucky to offer the drug now that it is approved.. More...

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Sept. 16, 2014 - Patent and license holders honored
Faculty members whose work has resulted in U.S. patents and licenses were honored Sept. 16 at the 2014 Celebration of Faculty Excellence. More...