 |
 Senior
Research Associate
Tel: (502) 852-6848
hmqazz01@gwise.louisville.edu
Dr. Qazzaz is currently a senior research associate
at the Department of Pathology and Laboratory Medicine, University
of Louisville, School of Medicine. Dr. Qazzaz received his
PhD degree at the University College of Dublin (UCD), Dublin,
Ireland in Biochemistry (1988) and completed his postdoctoral
fellowships in Biochemistry and Molecular Biology at the University
of Louisville.
Dr. Qazzaz’s research experience includes a combination
of molecular cloning, protein chemistry and natural product
analysis. His areas of specific scientific research center
around characterization, structural analysis, and biosynthesis
of a family of potentially new hormones known as the endogenous
mammalian cardenolides and their pathophysiologic function
in control of cellular ion transport activity. The model under
investigation is that of endogenous digoxin like immunoreactive
factor (DLIF) and ouabain like factor (OLF) and their interaction
with the sodium pump (Na,K ATPase; NKA) and its isoforms.
The approach is based on the theory of structure function
complementarity between endogenous receptors (NKA), endogenous
ligands (DLIF, OLF), and pharmacologic agents (digitalis,
ouabain).
He has published over 75 papers and abstracts in several prestigious
journals and has presented at several national and international
scientific conferences including the American Association
for Clinical Chemistry (AACC), Clinical Ligand Assay Society
(CLAS), American Society of Biochemistry and Molecular Biology
(ASBMB), and the Endocrine Society.
Along with other members of Dr. Valdes’ team, Dr.
Qazzaz was awarded first place recepient of the coveted Walter
Walser prize for best poster presentation at Clinical Ligand
Assay Society (CLAS 1999), first place winner/originality
for Faculty Research Day at at Univ. of Louisville, School
of Medicine 1999, first place winner of Sheard Sanford Medical
Student Award Competition at American Society of Clinical
Pathologists (ASCP 1998), best poster award at AACC National
Meeting 1995, and an honorable mention award for Student Research
Day at Univ. of Louisville, School of Medicine 1994.
Dr. Qazzaz, and the co-inventor Professor Roland Valdes,
Jr., recently received a licensing option from an industrial
corporation to develop immunoassays based on the discovery
of these drug-like molecules and their potential links to
heart disease.
|
 |
Contact:
Hassan Qazzaz, PhD
MDR Bldg., Rm 206
511 S. Floyd St.
Louisville, KY 40292
Tel: (502) 852-6848
Email: hmqazz01@gwise.louisville.edu
|
