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Department of Ophthalmology & Visual Sciences


Christopher A. Paterson, Ph.D., D.Sc.

Christopher A. Paterson, Ph.D., D.Sc.

"Vision research will become more globalized over the next ten years, due to the explosion of information technology. New sources of funding will need to support new ideas, such as moving glaucoma from pressure management to neuroprotection, photodynamic therapy and genetic kits for predicting eye disease at an earlier stage."

Internationally recognized for his on-going pioneering work in the field, Christopher Paterson brings a rich legacy of award-winning research, professional associations, editorial and administrative experience to the Kentucky Lions Eye Center. He works with lens and cataract research, continues a collaboration with Dr. Bhattercherjee in the area of ocular inflammation, and delves into applied physiology through the development, refinement and testing of new screening techniques and drug therapies in partnership with major pharmaceutical companies.

Despite his years of pioneering work in eye research, Dr. Paterson claims he 'fell into' the field while considering a career in medicine back in his native England. As a Research Fellow at Johns Hopkins, he became intrigued by the challenge of eye diseases, and found the eye itself a fascinating multi-faceted anatomical system. The retina as an extension of the brain, the sensory function of the eye, intraocular fluid flow, and the transparent function of the cornea and lens all appealed to his physiological and pharmacological background.

A former Director of Research and on-going Kentucky Lions Endowed Chair, Dr. Paterson continues to be a vibrant presence at the institute.

Current Position

Professor, Department of Ophthalmology & Visual Sciences Kentucky Lions Endowed Chair On Staff since 1986

Research Specialties

Cataract, Uveitis, Physiology of the eye

Contact Information

capate01@athena.louisville.edu
University of Louisville
Dept. Of Ophthalmology & Visual Science
301 E. Muhammad Ali Blvd.
Louisville, KY 40202
(502) 852-5460
FAX - (502) 852-7446

Current Grants

National Eye Institute/National Institute of Health 4/2001 - 6/2004 Principal Investigator, Grant 5R01 EY06918-14 A2 $600,00.00 period direct costs "Ocular Inflammation: Chemical and Physiological Aspects"

National Eye Institute/National Institute of Health 5/2001 - 4/2005 Principal Investigator, Grant 5R01 EY06916-10 A2 $700,00.00 period direct costs "Regulation of lens cation balance and distribution"

Novartis "Docosanoids in the eye" $80,000

Pharmacia "Cox-2 inhibitors in the eye" $75,000

Select Publications

Paterson, C.A., Zeng, J., Husseini, Z., Borchman, D., Delamere, N.A., Garland, D. and Jimenez-Asensio, J. Calcium ATPase and membrane structure in clear and cataractous human lenses. Curr. Eye Res. 16:333-338, 1997.

Bhattacherjee, P, Williams, BS and Paterson, CA. Responses of intraocular pressure and the pupil of feline eyes to prostoglandin EP1 and FP receptor agonists. Invest. Ophthalmol. Vis. Sci. 40:3047-3053, 1999.

Bhattacherjee, P., Paterson, C.A., Spellman, J.M., Graff, G. and Yanni, J.M. Pharmacological validation of a feline model of steroid-induced ocular hypertension. Arch Ophthalmol 117(3):361-364, 1999.

Education

Sheffield University, Sheffield, England B.Sc. 1963
University of London, England, Ph.D. 1968
University of London, England, D.Sc. 1986

Professional Societies and Affiliations

American Physiological Society, Association for Research in Vision and Ophthalmology, Association for Eye Research (Europe), New York Academy of Sciences, International Society for Eye Research, Royal Society of Medicine, American Association for the Advancement of Science, European Tissue Repair Society, American Academy of Ophthalmology, Sigma Xi, International Society of Ocular Trauma, and the International Ocular Inflammation Society.


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