Department of Obstetrics, Gynecology & Women's Health

Education:
PhD in Medical Microbiology & Immunology, Ohio State University, Columbus, OH
Post-doctoral work in Virology, Milton Hershey Med Sch, Penn State Univ, Hershey, PA
Post-doctoral work in Oncobiology, Boston Univ School of Medicine, Boston, MA,

Research Support

Honors
American College of Obstetrics & Gynecology, Searle-Donald F. Richardson Award, with Dr. Catherine Schneider - 1998.
Jewish Hospital Foundation Award for Research with Major Clinical Application, with Dr. D. Taylor - 1998.

Recent Publications:

Taylor DD, Gercel-Taylor C. Alterations in T-cell signal transduction molecules associated with recurrent spontaneous pregnancy loss. J Reprod Immunol, 63: 137-154, 2004 (Featured article).

Taylor DD, Gercel-Taylor C. Tumor-derived exosomes as mediates of T-cell signaling defects. Brit J Cancer, 92: 305-311, 2005 (Featured article).

Kim JW, Wieckowski E, Taylor DD, Reichert TE, Watkins S, Whiteside TL. FasL+ membraneous vesicles isolated from sera of patients with oral cancer induce apoptosis of activated T lymphocytes. Clin Cancer Res, 11: 1010-1020, 2005 (Featured article).

Saxena A, Yashar C, Taylor DD, Gercel-Taylor C. Cellular response to chemotherapy and radiation in cervical cancer. Amer J Obstet Gynecol, 192: 1399-1403, 2005.

Yashar, C.M., Spanos, W.J., Taylor, D.D., Gercel-Taylor, C. Potentiation of the radiation effect with genistein in cervical cancer cells. Gynecol Oncol, 99: 199-205, 2005.

Gercel-Taylor, C., Scobee, J.J., Taylor, D.D. Effect of chemotherapy on the mutation frequency of ovarian cancer cells at the HPRT locus. AntiCancer Res, 25: 2113-2117, 2005.

Gercel-Taylor, C. Diphenylamine assay of DNA fragmentation for chemosensitivity testing. Methods in Molecular Medicine, 111: 79-82, 2005.

Abdallah, M.A., Nakajima, ST., Lin, PC., Gercel-Taylor, Cicek. Plasma matrix metalloproteinase activity during the menstrual cycle of healthy ovulatory patients who underwent tubal ligation. Fertility & Sterility, 84(6): 1766-7, 2005.

Taylor, D.D., Akyol, S., Gercel-Taylor, C. Pregnancy-associated exosomes and their modulation of T-cell signaling. J Immunol, 176: 1534-1542, 2006.

Metzinger, D.S., Taylor, D.D., Gercel-Taylor, C. Induction of p53 and drug resistance following treatment with cisplatin or paclitaxel in ovarian cancer cell lines. Cancer Letters, 236: 302-308, 2006.

Taylor, D.D., Bohler, H.C., Gercel-Taylor, C. Pregnancy-linked suppression of TcR signaling pathways by a circulating factor absent in recurrent spontaneous pregnancy loss. Mol Immunol 43:1872-1880, 2006.

Akyol, S., Gercel-Taylor, C., Reynolds, L.C., Taylor, D.D. HSP-10 in ovarian cancer: Expression and suppression of T-cell signaling. Gynecologic Oncology, 101: 581-586, 2006.

Abdallah, M.A., Lin, P.C., Nakajima, S.T., Eblen, A.C., Kang, S., Gercel-Taylor, C. Comparisons of matrix metalloproteinase 1, 2, and 9 activity in periovulatory follicular fluid from natural and stimulated menstrual cycles. Fertility & Sterility, 85(3): 800-1, 2006.

Toler, C.R., Taylor, D.D., Gercel-Taylor, C. Loss of communication in ovarian cancer. American Journal of Obstetrics and Gynecology, 194(5): e27-31, 2006.

Randall-Whitis, L., Taylor, D.D., Gercel-Taylor, C. cDNA microarray analysis of gene expression in ovarian cancer cells after treatment with carboplatin and paclitaxel. Cancer Genomics and Proteomics. (in press)

Abdallah, M.A., Kang, S., Nakajima, S.T., Gercel-Taylor, C. Matrix metalloproteinase-9 activity in the plasma of patients after surgical resection of endometriomas. Fertility & Sterility, 85(6): 1847-8, 2006.