Kenneth R. McLeish, M.D. Professor of Medicine University of Louisville Health Care Outpatient Center 401 East Chestnut Street, Ste. 690 Louisville, KY 40202 502-852-5757 - Academic Office 502-813-6699 - Patient Appointments

Clinical Expertise

Nephrology; Bio-Chemistry; Molecular Biology; Glomerulonephritis

Board Certificaions

• American Board of Internal Medicine - Internal Medicine / Nephrology

Education and Training

• Medical School: Indiana University

• Residency: Indiana University Medical Center

• Fellowship: Indiana University Medical Center

Recent Publications

• Luerman GC, Powell DW, Uriarte SM, Cummins TD, Merchant ML, Ward RA, McLeish KR. Identification of phosphoproteins associated with human neutrophil granules following chemotactic peptide stimulation. Mol Cell Proteomics. 2010 Nov 19.

• Luerman GC, Uriarte SM, Rane MJ, McLeish KR. Application of proteomics to neutrophil biology. J Proteomics. 2010 Jan 3;73(3):552-61. Epub 2009 Jul 4. Review.

• Uriarte SM, Jog NR, Luerman GC, Bhimani S, Ward RA, McLeish KR. Counterregulation of clathrin-mediated endocytosis by the actin and microtubular cytoskeleton in human neutrophils. Am J Physiol Cell Physiol. 2009 Apr;296(4):C857-67. Epub 2009 Jan 28.

• Uriarte SM, McLeish KR, Ward RA. Anti-proteinase 3 antibodies both stimulate and prime human neutrophils. Nephrol Dial Transplant. 2009 Apr;24(4):1150-7. Epub 2008 Oct 24.

• Uriarte SM, Powell DW, Luerman GC, Merchant ML, Cummins TD, Jog NR, Ward RA, McLeish KR. Comparison of proteins expressed on secretory vesicle membranes and plasma membranes of human neutrophils. J Immunol. 2008 Apr 15;180(8):5575-81.

• Barati MT, Merchant ML, Kain AB, Jevans AW, McLeish KR, Klein JB. Proteomic analysis defines altered cellular redox pathways and advanced glycation end-product metabolism in glomeruli of db/db diabetic mice. Am J Physiol Renal Physiol. 2007 Oct;293(4):F1157-65. Epub 2007 Jul 3.

• Jog NR, Rane MJ, Lominadze G, Luerman GC, Ward RA, McLeish KR. The actin cytoskeleton regulates exocytosis of all neutrophil granule subsets. Am J Physiol Cell Physiol. 2007 May;292(5):C1690-700. Epub 2007 Jan 3.

• Jog NR, Jala VR, Ward RA, Rane MJ, Haribabu B, McLeish KR. Heat shock protein 27 regulates neutrophil chemotaxis and exocytosis through two independent mechanisms. J Immunol. 2007 Feb 15;178(4):2421-8.

• Barati MT, Rane MJ, Klein JB, McLeish KR. A proteomic screen identified stress-induced chaperone proteins as targets of Akt phosphorylation in mesangial cells. J Proteome Res. 2006 Jul;5(7):1636-46.

• Lominadze G, Ward RA, Klein JB, McLeish KR. Proteomic analysis of human neutrophils. Methods Mol Biol. 2006;332:343-56.