Shapiro to discuss new look at COPD care
Dr. Steven Shapiro takes a look at improved care for COPD patients.
Learning how to improve care for patients suffering from chronic obstructive pulmonary disease will be the focus of next month's Nancy Middleton Smith Lecture.
Dr. Steven D. Shapiro, M.D., will present the lecture at 8 a.m. Thursday, March 4 in the Ambulatory Care Building's auditorium at the University of Louisville Health Science campus.
Dr. Shapiro, chairman of the Department of Medicine, and Jack D. Myers Professor of Medicine at the University of Pittsburgh, will discuss ways of understanding the mechanisms that lead to COPD, thinking of COPD as a syndrome and improving the care of COPD patients.
"It is a pleasure to visit the University of Louisville," Dr. Shapiro said. "I have great respect for the institution and look forward to learning more.
"This trip is especially gratifying since I get to catch up with two close colleagues: Rod Folz and Jesse Roman," he said. "Jesse and I were Fellows together at Washington University, while Rod was an MSTP student there at the time. There are none better than these two."
A physician-scientist whose research is focused on the role of proteinases in COPD, infectious diseases and lung cancer, Dr. Shapiro also is the author of over 200 peer-reviewed manuscripts, chapters and reviews.
Dr. Shapiro's laboratory focuses on the role of inflammatory cell derived proteinases in the progression of COPD/emphysema and lung cancer. He originally cloned and knocked out macrophage elastase to demonstrate that mice deficient in MMP-12 are completely protected from the development of cigarette smoke-induced emphysema.
His lab has continued to study the contribution of numerous inflammatory cell-derived proteinases in emphysema and lung cancer progression using gene targeting in mice. More recently, his lab has begun to study the role of repair (or lack thereof) in the progression of emphysema by using lineage-tagging approaches to study putative stem cell populations residing within the lung.
A native of Chicago, Dr. Shapiro obtained his undergraduate and medical degrees from the University of Chicago. He then completed both an Internal Medicine residency and fellowship in Respiratory and Critical Care at the Washington University School of Medicine.
Prior to his move to Pittsburgh, Dr. Shapiro was the Parker B. Francis Professor of Medicine at Harvard Medical School and the Chief of the Division of Pulmonary and Critical Care at Brigham and Women's Hospital.
In addition, Dr. Shapiro was the Editor-in-Chief of the American Journal of Respiratory Cell and Molecular Biology and serves on the editorial board of the Journal of Clinical Investigation, Journal of Experimental Medicine and Journal of COPD.
Dr. Shapiro also serves on the advisory committee of the National Heart, Lung and Blood Institute.