Jesse Roman, M.D.

Jesse Roman, M.D. Professor of Medicine Chairman, Department of Medicine Distinguished University Scholar Acting Chief, Division of Pulmonary, Critical Care & Sleep Disorders Medicine University of Louisville Health Care Outpatient Center 401 East Chestnut Street, Ste. 310 Louisville, KY 40202 502-852-5241 - Academic Office 502-813-6500 - Patient Appointments

Clinical Expertise

Interstitial Lung Disease; Pulmonary Fibrosis; Lung Cancer

Board Certifications

• American Board of Internal Medicine - Internal Medicine / Pulmonary Disease

Education and Training

• Medical School: University of Puerto Rico

• Residency: San Juan Veterans Affairs Medical Center

• Fellowship: Washington University

Recent Publications

• Ritzenthaler JD, Roser-Page S, Guidot DM, Roman J. Nicotinic Acetylcholine Receptors are Sensors for Ethanol in Lung Fibroblasts. Alcohol Clin Exp Res. 2013 Feb 19. doi: 10.1111/acer.12044. [Epub ahead of print] PubMed PMID: 23421903.

• Wongtrakool C, Grooms K, Ping XD, Rivera H, Ward J, Roser-Page S, Roman J, Brown LA, Gauthier TW. In utero nicotine exposure promotes M2 activation in neonatal mouse alveolar macrophages. Pediatr Res. 2012 Aug;72(2):147-53. PubMed PMID: 22562289; PubMed Central PMCID: PMC3600420.

• Kubiak NT, Guidot DM, Trimm RF, Kamen DL, Roman J. Recruitment and retention in academic medicine--what junior faculty and trainees want department chairs to know. Am J Med Sci. 2012 Jul;344(1):24-7. doi: 10.1097/MAJ.0b013e318258f205. PubMed PMID: 22744375.

• Sueblinvong V, Neujahr DC, Mills ST, Roser-Page S, Ritzenthaler JD, Guidot D, Rojas M, Roman J. Predisposition for disrepair in the aged lung. Am J Med Sci. 2012 Jul;344(1):41-51. doi: 10.1097/MAJ.0b013e318234c132. PubMed PMID: 22173045; PubMed Central PMCID: PMC3395069.

• Wongtrakool C, Wang N, Hyde DM, Roman J, Spindel ER. Prenatal nicotine exposure alters lung function and airway geometry through α7 nicotinic receptors. Am J Respir Cell Mol Biol. 2012 May;46(5):695-702. doi: 10.1165/rcmb.2011-0028OC. Epub 2012 Jan 12. PubMed PMID: 22246862; PubMed Central PMCID: PMC3359906.

• Deng Z, Cheng Z, Xiang X, Yan J, Zhuang X, Liu C, Jiang H, Ju S, Zhang L, Grizzle W, Mobley J, Roman J, Miller D, Zhang HG. Tumor cell cross talk with tumor-associated leukocytes leads to induction of tumor exosomal fibronectin and promotes tumor progression. Am J Pathol. 2012 Jan;180(1):390-8. doi: 10.1016/j.ajpath.2011.09.023. Epub 2011 Nov 7. PubMed PMID: 22067905.

• Reddy RC, Rehan VK, Roman J, Sime PJ. PPARs: Regulators and Translational Targets in the Lung. PPAR Res. 2012;2012:342924. doi: 10.1155/2012/342924. Epub 2012 Nov 4. PubMed PMID: 23213318; PubMed Central PMCID: PMC3503434.

• Ramirez A, Ballard EN, Roman J. TGFβ1 Controls PPARγ Expression, Transcriptional Potential, and Activity, in Part, through Smad3 Signaling in Murine Lung Fibroblasts. PPAR Res. 2012;2012:375876. Epub 2012 Sep 10. PubMed PMID: 22997505; PubMed Central PMCID: PMC3444904.

• Mehta AJ, Joshi PC, Fan X, Brown LA, Ritzenthaler JD, Roman J, Guidot DM. Zinc supplementation restores PU.1 and Nrf2 nuclear binding in alveolar macrophages and improves redox balance and bacterial clearance in the lungs of alcohol-fed rats. Alcohol Clin Exp Res. 2011 Aug;35(8):1519-28. doi: 10.1111/j.1530-0277.2011.01488.x. Epub 2011 Mar 29. PubMed PMID: 21447000; PubMed Central PMCID: PMC3128659.

• Fioret D, Perez RL, Roman J. Management of idiopathic pulmonary fibrosis. Am J Med Sci. 2011 Jun;341(6):450-3. doi: 10.1097/MAJ.0b013e31821fbdbc. PubMed PMID: 21613933.

• Fioret D, Perez RL, Perez T, Roman J. A case of progressive lung fibrosis. Am J Med Sci. 2011 Jun;341(6):428-30. doi: 10.1097/MAJ.0b013e31821a9d52. PubMed PMID: 21613928.

• Roman J. The 2010 Southern Society for Clinical Investigation president's symposium: Idiopathic pulmonary fibrosis. Am J Med Sci. 2011 Jun;341(6):427. doi: 10.1097/MAJ.0b013e31821a9d40. PubMed PMID: 21613927.