Rodney J. Folz, M.D., Ph.D.

Rodney J. Folz, M.D., Ph.D. Professor of Medicine Chief, Division of Pulmonary, Critical Care and Sleep Disorders Medicine Distinguished University Scholar University of Louisville Health Care Outpatient Center 401 East Chestnut Street, Ste. 310 Louisville, KY 40202 502-852-5841 - Academic Office 502-813-6500 - Patient Appointments

Clinical Expertise

Chronic obstructive pulmonary disease; Interstitial lung disease; Asthma; Pulmonary arterial hypertension; Pulmonary complications of bone marrow transplant patients; Cystic fibrosis

Board Certifications

• American Board of Internal Medicine - Internal Medicine / Pulmonary Disease

Education and Training

• Medical School: Washington University

• Residency: Duke University

• Fellowship: Duke University

Recent Publications

• Terson de Paleville DG, McKay WB, Folz RJ, Ovechkin AV. Respiratory Motor Control Disrupted by Spinal Cord Injury: Mechanisms, Evaluation, and Restoration. Transl Stroke Res. 2011 Dec 1;2(4):463-473.

• Zelko IN, Stepp MW, Vorst AL, Folz RJ. Histone acetylation regulates the cell-specific and interferon-γ-inducible expression of extracellular superoxide dismutase in human pulmonary arteries. Am J Respir Cell Mol Biol. 2011 Nov;45(5):953-61. Epub 2011 Apr 14.

• Kelsey CR, Horwitz ME, Chino JP, Craciunescu O, Steffey B, Folz RJ, Chao NJ, Rizzieri DA, Marks LB. Severe pulmonary toxicity after myeloablative conditioning using total body irradiation: an assessment of risk factors. Int J Radiat Oncol Biol Phys. 2011 Nov 1;81(3):812-8. Epub 2010 Oct 6.

• Panoskaltsis-Mortari A, Griese M, Madtes DK, Belperio JA, Haddad IY, Folz RJ, Cooke KR; American Thoracic Society Committee on Idiopathic Pneumonia Syndrome. An official American Thoracic Society research statement: noninfectious lung injury after hematopoietic stem cell transplantation: idiopathic pneumonia syndrome. Am J Respir Crit Care Med. 2011 May 1;183(9):1262-79. Review.

• Zelko IN, Folz RJ. Extracellular superoxide dismutase attenuates release of pulmonary hyaluronan from the extracellular matrix following bleomycin exposure. FEBS Lett. 2010 Jul 2;584(13):2947-52. Epub 2010 May 21.

• Zelko IN, Mueller MR, Folz RJ. CpG methylation attenuates Sp1 and Sp3 binding  to the human extracellular superoxide dismutase promoter and regulates its cell-specific expression. Free Radic Biol Med. 2010 Apr 1;48(7):895-904. Epub 2010 Jan 14.

• Zhang J, Ma J, Zhou S, Hubbs JL, Wong TZ, Folz RJ, Evans ES, Jaszczak RJ, Clough R, Marks LB. Radiation-induced reductions in regional lung perfusion: 0.1-12 year data from a prospective clinical study. Int J Radiat Oncol Biol Phys. 2010 Feb 1;76(2):425-32. Epub 2009 Jul 23.

• Itoh S, Ozumi K, Kim HW, Nakagawa O, McKinney RD, Folz RJ, Zelko IN, Ushio-Fukai M, Fukai T. Novel mechanism for regulation of extracellular SOD transcription and activity by copper: role of antioxidant-1. Free Radic Biol Med. 2009 Jan 1;46(1):95-104. Epub 2008 Oct 21.

• Zelko IN, Mueller MR, Folz RJ. Transcription factors sp1 and sp3 regulate expression of human extracellular superoxide dismutase in lung fibroblasts. Am J Respir Cell Mol Biol. 2008 Aug;39(2):243-51. Epub 2008 Feb 28.

• Mao J, Kocak Z, Zhou S, Garst J, Evans ES, Zhang J, Larrier NA, Hollis DR, Folz RJ, Marks LB. The impact of induction chemotherapy and the associated tumor  response on subsequent radiation-related changes in lung function and tumor response. Int J Radiat Oncol Biol Phys. 2007 Apr 1;67(5):1360-9. Epub 2007 Feb 2.