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Betty C. Villafuerte, M.D.
Appointments
- Associate Professor of Medicine
Departments
Location
Phone Number
- 502-852-5237
Email Address
Website
Bio
Dr. Villafuerte joined University of Louisville faculty in 2003. Previously she was on the faculty of Emory University as Assistant Professor (1993-2003). She is a member of the Endocrine Society and the American Diabetes Association. Her research is focused on cloning and identification of genes critical to insulin actions. She holds a patent for Insulin-Responsive DNA Binding Protein-1 and Methods to Regulate Insulin-Responsive Genes, under examination by the USPTO and Europe PTO.
Educational Background
- Bachelor of Science in Zoology, University of the Philippines, 1977
- Medical Degree, University of the Philippines, 1981
- Internal Medicine Residency, State University of New York, Mercy Hospital, Buffalo, NY, 1986-1989
- Clinical and Research Fellowship in Endocrinology and Metabolism, Emory University School of Medicine, Atlanta, GA, 1989-1992
Research Interests
- Diabetes
- Insulin Action
- Obesity & Weight Control
Publications
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Recent Publications
Moore, J.P, Klausing, B.T., Villafuerte, B.C., Winters, S.J. Targeted over-expression of PACAP increases follistatin and reduces gonadotropin subunit mRNAs. Endocrinology 150 (10): 4802-4809, Oct. 2009.
Villafuerte, B.C., Barati, M.T, Song, Y., Moore, J.P., Epstein, P.N., Portillo, J.: Targeted over-expression of insulin-response element binding protein 1 (IRE-BP1) in beta cells reproduces type 2 diabetes. Endocrinology 150 (6): 2611-2617, Aug. 2009. Featured in April 2009 issue of Endocrine News.
Maudar, V., Winters, S.J., Villafuerte, B.C Hot flashes and fatigue relieved by Metformin. Endocrine Practice, 15 (1): 30-34, Jan. 2009.
Chahal, J., Chen, C.C., Rane, M.J., Moore, J.P., Barati, M.T., Song, Y., Villafuerte, B.C.: Regulation of Insulin-response element binding protein-1 in obesity and diabetes: Potential role in impaired insulin-induced gene transcription. Endocrinology 149(10): 4829-4836, Oct. 2008. Featured in Aug. 2008 issue of Endocrine News.
Villafuerte, B.C, Kaytor, E.N: An insulin-response element binding protein that ameliorates hyperglycemia in diabetes: Regulation of glucose control by the genomic actions of insulin. Journal of Biological Chemistry 280(20): 20010-20020, May 20, 2005.
Villafuerte, B.C, Phillips, L.S, Rane, M.J, Zhao, W: Insulin-response element-binding protein 1: A novel Akt substrate involved in transcriptional action of insulin. Journal of Biological Chemistry 279(35): 36650-36659, Aug. 27, 2004.
Villafuerte, B.C, Fine, J, Bai, Y, Zhao, W, Tagra, K, Fleming, S, Hausman, D, DiGirolamo, M: Expression of leptin and IGF-1 are highly correlated and region-specific in adipose tissue of growing rats. Obesity Research 8(9): 646-655, 2000.
Phillips, L.S, Pao, C.I, Villafuerte, B.C: Molecular regulation of insulin-like growth factor-1 (IGF-1) and its principal binding protein, IGFBP-3. In: Progress in Nucleic Acid Research and Molecular Biology, Moldave, K. And Cohen, W. Eds., Academic Press, pp 195-265, 1998.
