Atul R. Chugh, M.D., M.P.H.

Assistant Professor of Medicine
Division of Cardiovascular Medicine
University of Louisville School of Medicine
Director, Preventative Cardiology and Hypertension
Director, Advanced Cardiac Imaging

Clinical Interests:

• Preventative Cardiovascular Medicine
• Coronary artery disease, chest pain syndrome
• Cardiac Nuclear Imaging
• Cardiac MR imaging
• Cardiac PET imaging
• CT Angiography, Cardiac CT

Clinical Research Interests:

• Cardiac Regenerative Therapies
• Cardiac Markers in acute coronary syndromes
• Coronary/cardiac imaging
• Cardiovascular risk prediction

Preclinical Interests:

• Pharmacologic therapic attenuation of myocardial remodeling
• Rodent models of stem cell-mediated myocardial repair
• Epigenetic molecular signatures  involved in cardiogenesis

Selected publications:

• Rehman A, Yousaf S, Chugh A. Thrombolysis in submassive pulmonary embolism, prudent or puerile? BMJ Case Rep. 2013 Jan 24;2013. pii: bcr2012007549. doi: 10.1136/bcr-2012-007549.
• Loughran JH, Chugh AR, Ismail I, Bolli R. Stem cell therapy: promising treatment in heart failure? Curr Heart Fail Rep. 2013 Mar;10(1):73-80. doi: 10.1007/s11897-012-0128-2.
• Chugh AR, Beache GM, Loughran JH, Mewton N, Elmore JB, Kajstura J, Pappas P, Tatooles A, Stoddard MF, Lima JA, Slaughter MS, Anversa P, Bolli R. Administration of cardiac stem cells in patients with ischemic cardiomyopathy: the SCIPIO trial: surgical aspects and interim analysis of myocardial function and viability by magnetic resonance. Circulation. 2012 Sep 11;126(11 Suppl 1):S54-64.
• Loughran JH, Elmore JB, Waqar M, Chugh AR, Bolli R. Cardiac stem cells in patients with ischemic cardiomyopathy: discovery, translation, and clinical investigation. Curr Atheroscler Rep. 2012 Oct;14(5):491-503. doi: 10.1007/s11883-012-0273-9.
• He JQ, Vu DM, Hunt G, Chugh A, Bhatnagar A, Bolli R. Human cardiac stem cells isolated from atrial appendages stably express c-kit. PLoS One. 2011;6(11):e27719. doi: 10.1371/journal.pone.0027719. Epub 2011 Nov 28.
• Nacif MS, Chugh AR, Lima JA, Bluemke DA. How should infarct size be measured on LGE sequences? A call for a change in the guidelines. JACC Cardiovasc Imaging. 2011 Nov;4(11):1223; author reply 1224. doi: 10.1016/j.jcmg.2011.08.010.
• Bolli R, Chugh AR, D'Amario D, Loughran JH, Stoddard MF, Ikram S, Beache GM, Wagner SG, Leri A, Hosoda T, Sanada F, Elmore JB, Goichberg P, Cappetta D, Solankhi NK, Fahsah I, Rokosh DG, Slaughter MS, Kajstura J, Anversa P. Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial. Lancet. 2011 Nov 26;378(9806):1847-57. doi: 10.1016/S0140-6736(11)61590-0. Epub 2011 Nov 14.
• Chugh A, Bakris G. Intensive lowering of systolic blood pressure to a target of less than 120 mm Hg has no effect on the rate of fatal and non-fatal major cardiovascular events in high-risk patients with type 2 diabetes. Evid Based Med. 2010 Oct;15(5):142-3. doi: 10.1136/ebm1099. Epub 2010 Jul 28.