Andrew P. DeFilippis, MD, MSc

Assistant Professor of Medicine
Director, Advanced Cardiac Support Center

Dr. Andrew P. DeFilippis is an academic cardiologist with clinical, human subject research, and educational expertise, in the diagnosis, treatment and prevention of acute coronary atherothrombosis / chronic atherosclerosis.

Research Interests

• Platelet Activation and Coronary Thrombosis
• Aspirin-Insensitive Thromboxane Generation and Coronary Thrombosis
• Atherosclerosis

Recent Publications

• Defilippis AP, Blaha MJ, Martin SS, Reed RM, Jones SR, Nasir K, Blumenthal RS, Budoff MJ. Nonalcoholic fatty liver disease and serum lipoproteins: The Multi-Ethnic Study of Atherosclerosis. Atherosclerosis. 2013 Apr;227(2):429-36. doi: 10.1016/j.atherosclerosis.2013.01.022. Epub 2013 Jan 29.
• DeFilippis AP, Blaha MJ, Ndumele CE, Budoff MJ, Lloyd-Jones DM, McClelland RL, Lakoski SG, Cushman M, Wong ND, Blumenthal RS, Lima J, Nasir K. The association of Framingham and Reynolds risk scores with incidence and progression of coronary artery calcification in MESA (Multi-Ethnic Study of Atherosclerosis). J Am Coll Cardiol. 2011 Nov 8;58(20):2076-83. doi: 10.1016/j.jacc.2011.08.022.
• Blaha MJ, Budoff MJ, DeFilippis AP, Blankstein R, Rivera JJ, Agatston A, O'Leary DH, Lima J, Blumenthal RS, Nasir K. Associations between C-reactive protein, coronary artery calcium, and cardiovascular events: implications for the JUPITER population from MESA, a population-based cohort study. Lancet. 2011 Aug 20;378(9792):684-92. doi: 10.1016/S0140-6736(11)60784-8.
• Blaha MJ, DeFilippis AP, Rivera JJ, Budoff MJ, Blankstein R, Agatston A, Szklo M, Lakoski SG, Bertoni AG, Kronmal RA, Blumenthal RS, Nasir K. The relationship between insulin resistance and incidence and progression of coronary artery calcification: the Multi-Ethnic Study of Atherosclerosis (MESA). Diabetes Care. 2011 Mar;34(3):749-51. doi: 10.2337/dc10-1681. Epub 2011 Feb 3.
• McEvoy JW, Blaha MJ, Defilippis AP, Budoff MJ, Nasir K, Blumenthal RS, Jones SR. Coronary artery calcium progression: an important clinical measurement? A review of published reports. J Am Coll Cardiol. 2010 Nov 9;56(20):1613-22. doi: 10.1016/j.jacc.2010.06.038.
• Defilippis AP, Blaha MJ, Jacobson TA. Omega-3 Fatty acids for cardiovascular disease prevention. Curr Treat Options Cardiovasc Med. 2010 Aug;12(4):365-80. doi: 10.1007/s11936-010-0079-4.
• Tota-Maharaj R, Defilippis AP, Blumenthal RS, Blaha MJ. A practical approach to the metabolic syndrome: review of current concepts and management. Curr Opin Cardiol. 2010 Sep;25(5):502-12. doi: 10.1097/HCO.0b013e32833cd474.
• DeFilippis AP, Kramer HJ, Katz R, Wong ND, Bertoni AG, Carr J, Budoff MJ, Blumenthal RS, Nasir K. Association between coronary artery calcification progression and microalbuminuria: the MESA study. JACC Cardiovasc Imaging. 2010 Jun;3(6):595-604. doi: 10.1016/j.jcmg.2010.01.008.
• Defilippis AP, Tellez I, Winawer N, Di Francesco L, Manning KD, Kripalani S. On-site Night Float by Attending Physicians: A Model to Improve Resident Education and Patient Care. J Grad Med Educ. 2010 Mar;2(1):57-61. doi: 10.4300/JGME-D-09-00073.1.
• Rowe DO, DeFilippis A, Dantzler DM Jr, Kripalani S, Doyle J, Sperling L. Assessment of gender-specific preventive cardiovascular knowledge among house staff: Potential impact on cardiovascular management. Gend Med. 2009 Sep;6(3):471-8. doi: 10.1016/j.genm.2009.09.002.
• DeFilippis AP, Harper CR, Cotsonis GA, Jacobson TA. Effect of baseline plasma fatty acids on eicosapentaenoic acid levels in individuals supplemented with alpha-linolenic acid. Int J Food Sci Nutr. 2009;60 Suppl 5:28-37. doi: 10.1080/09637480802304481. Epub 2009 May 25.
• Blaha MJ, Bansal S, Rouf R, Golden SH, Blumenthal RS, Defilippis AP. A practical "ABCDE" approach to the metabolic syndrome. Mayo Clin Proc. 2008 Aug;83(8):932-41. doi: 10.4065/83.8.932.
• DeFilippis AP, Bansal S, Blumenthal RS. Long-term follow-up of the West of Scotland Coronary Prevention Study. N Engl J Med. 2008 Jan 10;358(2):194; author reply 194-5.
• DeFilippis AP, Larned JM, Cole JH, Nell-Dybdahl C, Miller JI 3rd, Sperling LS. Clues to cardiovascular risk: an office-based approach. Prev Cardiol. 2007 Winter;10(1):36-41.
• Wickramasinghe SR, DeFilippis AP, Lloyd-Jones DM, Blumenthal RS. A convenient tool to profile patients for generalized cardiovascular disease risk in primary care. Am J Cardiol. 2009 Apr 15;103(8):1174-7. doi: 10.1016/j.amjcard.2008.12.040. Epub 2009 Feb 28.

Reviewer

• JAMA
• American Journal of Cardiology
• American Heart Journal
• American Journal of Medicine
• Journal of Hospital Medicine
• US Preventive Services Task Force
• International Journal of Food Sciences and Nutrition
• Cerebrovascular Disease