Kyung U. Hong, PhD

Assistant Professor of Medicine
Tel.: (502) 852-0686
Email Dr. Hong
Dr. Hong received his B.S. from University of California Davis and M.S. & Ph.D. from University of Rochester School of Medicine. He is currently interested in understanding the cardiac progenitor/stem cell biology and its application to clinical settings. He is experienced in diverse fields of biomedicine ranging from stem cell biology to molecular cancer biology. His previous research involved elucidating and characterizing the stem cells of the conducting airway epithelium using innovative transgenic and knockout mouse technology. During his postdoctoral training, he further extended his expertise to the fields of biochemistry and molecular biology by studying the mechanisms and functional importance of various post-translational modifications of novel tumor-associated proteins in the cell division process. He has recently joined the Cardiology research group at University of Louisville to become a part of the ongoing research effort focused on the cardiac stem cell biology.
Selected Publications:
Hong KU, Kim HJ, Kim HS, Seong YS, Hong KM, Bae CD, Park J. 2009. Cdk1-Cyclin B1-mediated phosphorylation of tumor-associated microtubule-associated protein/cytoskeleton-associated protein 2 in mitosis. J Biol Chem. 284(24):16501-12.
Hong KU, Kim E, Bae CD, Park J. 2009. TMAP/CKAP2 is essential for proper chromosome segregation. Cell Cycle. 8(2):314-24. [Cover issue]
Hong KU, Park YS, Seong YS, Kang D, Bae CD, Park J. 2007. Functional importance of the anaphase-promoting complex-Cdh1-mediated degradation of TMAP/CKAP2 in regulation of spindle function and cytokinesis. Mol Cell Biol. 27(10):3667-81.
Hong KU, Reynolds SD, Watkins S, Fuchs E, Stripp BR. 2004. Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium. Am J Pathol. 164(2):577-88.
Hong KU, Reynolds SD, Giangreco A, Hurley CM, Stripp BR. 2001. Clara cell secretory protein-expressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion. Am J Respir Cell Mol Biol. 24(6):671-81. [Cover issue]

