The basic research activities of the Division are performed in the Institute of Molecular Cardiology (IMC), which is an integral part of the  Division of Cardiovascular Medicine and of the Cardiology Training Program.  The Institute of Molecular Cardiology consists of a team of basic and translational cardiovascular scientists who work together to advance our understanding of the molecular basis of myocardial ischemia/reperfusion injury and to develop novel therapeutic approaches, including gene therapy and stem cell-mediated cardiac repair.  The Institute of Molecular Cardiology occupies over 25,000 square feet of state-of-the-art research space (located on the first floor of the Medical Research Building and the Baxter Biomedical Research I, and the fourth floor of the Baxter Biomedical Research II ), offering outstanding facilities and equipment for virtually any type of basic investigation.  A total of 14 faculty and over 50 other members (postdoctoral Fellows, Research Associates, students, staff, etc.) work in the Institute of Molecular Cardiology.  The strength of the Institute of Molecular Cardiology, however, is not solely in these numbers but, most importantly, in the extraordinary expertise and cohesiveness of its members.  The 14 faculty who work in the Institute of Molecular Cardiology have diverse but complementary areas of expertise encompassing molecular biology, gene knockout/transgenesis, signaling, biochemistry, proteomics, pharmacology, pathology, physiology, electrophysiology, and translational research.  These investigators work together in a multidisciplinary approach, as documented by numerous joint publications and grants.  The Institute of Molecular Cardiology has been extremely productive, with over 150 publications since the arrival of Dr. Bolli at the University of Louisville in 1994.  A list of publications is available at (http://louisville.edu/medschool/cardiology/publication/Publication.html).  The Institute of Molecular Cardiology is currently supported by 16 active NIH grants, including two Program Project Grants.  Members of the Institute of Molecular Cardiology have achieved leadership positions in the American Heart Association, the NIH, the International Society for Heart Research, the American Physiological Society, and other scientific bodies.  Institute of Molecular Cardiology faculty are routinely invited speakers at national and international meetings and are asked to moderate sessions at these conferences.