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CPR training at the state fair wins top award for UofL cardiologist

CPR training at the state fair wins top award for UofL cardiologist

Lorrel Brown, M.D.

It stands to reason: If you want to educate large numbers of people, go where large numbers of people go.

In Dr. Lorrel E. Brown’s case, that place was the Kentucky State Fair – and the nation’s premier cardiology association has presented her an award for her innovative thinking.

Brown, assistant professor of medicine in UofL’s Division of Cardiovascular Medicine, won first place in the category of “Young Investigator Awards in Cardiovascular Health Outcomes and Population Genetics” from the American College of Cardiology earlier this month. The award was presented at the organization’s 65th Annual Scientific Session in Chicago. It also was published in the April 5 issue of the Journal of the American College of Cardiology.

Brown headed a group of researchers that included Dr. Glenn Hirsch, associate professor of medicine, cardiology fellows Dr. Wendy Bottinor and Dr. Avnish Tripathi, medical student Travis Carroll, Dr. Bill Dillon who founded the organization Start the Heart Foundation and Chris Lokits  of Louisville Metro Emergency Medical Services, Office of Medical Direction and Oversight. They tackled the problem of surviving cardiac arrest – the sudden stopping of the heart – by increasing the number of people trained in hands-only cardiopulmonary resuscitation (CPR).

Titled “CPR at the State Fair: A 10-minute Training Session is Effective in Teaching Bystander CPR to Members of At-risk Communities,” the research effort brought CPR training to the Kentucky State Fair’s Health Pavilion in August 2015.

Nearly 400,000 people in the United States have out-of-hospital cardiac arrest each year, she said, or nearly 40 people every hour. Only one in 10 survives.

“The vast majority of people who suffer cardiac arrest don’t experience it in a well-equipped hospital with highly trained medical staff,” Brown said. “They experience it as they go about their daily lives, and just 30 percent of cardiac arrest victims receive CPR, usually from bystanders. Yet we know that bystander CPR dramatically improves chances for survival.”

The group created a 10-minute training module that uses a short video and hands-on coaching to teach people the basics of hands-only CPR. To further determine their mastery of CPR, participants completed a post-training survey and were asked to return to the training site at the fair one hour after training to re-test their CPR ability.

The state fair location also provided an additional benefit: the ability to reach people from communities and counties throughout Kentucky with low rates of bystander CPR.

“In Jefferson County alone, bystander CPR rates vary dramatically according to zip code, ranging from 0 percent to 100 percent,” Brown said. “We know there is the same variation throughout the state, and 77 percent of the Jefferson County residents we trained at the fair were from zip code areas with bystander CPR rates under the national average of 31 percent.”

Since the 2015 fair, Brown has led efforts to conduct bystander CPR training at other locations. “Through the Take It to the Heart tour with KentuckyOne Health, we provided this training in hospital lobbies throughout the state, at UofL women's and men's basketball games and even at the Capitol in Frankfort with the Kentucky Senate,” she said. “Through these efforts, we have trained more than 1,000 individuals in CPR and educated another 43,000. We hope that these efforts not only raise the rates of bystander CPR and survival from cardiac arrest in our own communities, but also serve as a model for other communities.”

Brown will bring the training back to the Kentucky State Fair again this year. “These results suggest that by providing brief trainings in public venues, such as the state fair, we can effectively train people and potentially improve the rate of bystander CPR in this country,” she said.

Organizations or businesses also can schedule their own bystander CPR training session via the Start The Heart Foundation, for which Brown serves as a board member, by calling 502-852-1837.

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About the Young Investigator Awards

The American College of Cardiology’s Young Investigator Awards encourages and recognizes young scientific investigators of promise. To be considered for a Young Investigator Award, candidates submitted an abstract summarizing any problem relating to cardiovascular disease. Five finalists were selected in each of four award categories and invited to attend the Scientific Session to present their work during the Young Investigator Awards Competition.

About the American College of Cardiology

The American College of Cardiologyis a 52,000-member medical society that is the professional home for cardiovascular care physicians. The mission of the college is to transform cardiovascular care and to improve heart health. The college operates national registries to measure and improve care, offers cardiovascular accreditation to hospitals and institutions, provides professional medical education, disseminates cardiovascular research and bestows credentials upon cardiovascular specialists who meet stringent qualifications.

 

A new player revealed in nerve growth process

Role of adaptor protein CD2AP in neuron sprouting discovered by UofL researchers could lead to therapies for Alzheimer’s disease, stroke recovery and spinal cord injury
A new player revealed in nerve growth process

Benjamin Harrison, Ph.D., Jeffrey Petruska, Ph.D. and Kristofer Rau, Ph.D.

University of Louisville researchers have discovered that a protein previously known for its role in kidney function also plays a significant role in the nervous system. In an article featured in the April 13 issue of The Journal of Neuroscience, they show that the adaptor protein CD2AP is a key player in a type of neural growth known as collateral sprouting.

In the first research to be published on this protein’s role in the nervous system, Benjamin Harrison, Ph.D., a postdoctoral fellow in the Department of Anatomical Sciences and Neurobiology and lead author of the article, and his colleagues show that CD2AP, an adaptor protein, orchestrates a complex arrangement of other proteins that controls the branching of nerve axons, the tendrils reaching out from the nerve cell to connect to other nerve cells, skin and organs. This nerve growth occurs in uninjured nerve cells as they extend their reach and create new connections.

“CD2AP brings in all the correct players, forms a multi-protein complex and coordinates that multi-protein complex to achieve growth of the neurons,” Harrison said. “There are a whole bunch of proteins that it could bring together, but it only brings together the correct proteins to create the correct response. In this case, it changes the structure of the axons through sprouting and elongation.”

This axon sprouting may be helpful, but too much of it can be harmful. In normal adult cells, this growth creates new connections and can lead to improved functionality after an injury or stroke. However, if the axons sprout uncontrollably, the result can be exacerbated epilepsy, blood pressure spikes or neuropathic pain. The researchers hope this new understanding of the nerve growth process will lead to therapies that can improve healing and recovery of function following nerve damage while minimizing excessive growth.

“Through targeting this molecule, we could help the body’s natural healing process to coordinate the appropriate growth,” Harrison said.

The research team, based in the lab of Jeffrey Petruska, Ph.D., associate professor in the Department of Anatomical Sciences and Neurobiology and the Department of Neurological Surgery and the article’s corresponding author, identified CD2AP as a player in the neurological system via a screen to detect genes associated with neuron growth. Their research examined how CD2AP interacts with various molecules in controlling the neural sprouting process, in particular they studied its relationship with nerve growth factor (NGF).

“People have been studying nerve growth factor and the responses it induces for a while, but this protein (CD2AP) forms a nice link between NGF and the response in the cell,” Harrison said.

Previous research also has associated CD2AP with genetic changes among individuals with Alzheimer’s disease and it may be helpful in understanding the mechanisms involved in Parkinson’s Disease, Huntington’s Disease and spinal cord injuries.

Petruska says this work relates closely to other research being conducted at UofL’s Kentucky Spinal Cord Injury Research Center (KSCIRC). He says that understanding these molecular processes could one day be used to amplify the activity-based therapies such as locomotor training now being done with spinal cord injury patients by UofL faculty at Frazier Rehab Center, a part of KentuckyOne Health. Locomotor training helps spinal cord injury patients achieve functional recovery through standing and stepping activity.

“We are starting to discover that there are different modes of nerve growth and different sets of genes that control different kinds of growth,” Petruska said. “This is particularly important as it relates to locomotor training. When you train, you enhance the growth factor environment of the injured spinal cord, and those growth factors are involved in the axon plasticity. This mode that we study is dependent on the growth factors.”

Harrison, who also is part of the Kentucky Biomedical Research Infrastructure Network (KBRIN), plans to pursue research aimed at developing a drug to provide appropriate nerve growth for spinal cord injury patients.

“My dream,” Harrison said, “is to one day do a clinical trial with a drug that targets this protein and can enhance the ability of the patients to respond to the activity-based rehabilitation (locomotor training) that they are doing at Frazier Rehab Center.”

High school student Cassa Drury earned co-authorship on publication of original research

One member of the research team and a co-author on the publication that first described the role of CD2AP in the nervous system is Cassa Drury, a junior at Louisville’s duPont Manual High School. Drury has worked in the lab of Jeffrey Petruska, Ph.D., associate professor in UofL’s Department of Anatomical Sciences and Neurobiology, since he mentored her during middle school science fair competitions. As a middle schooler, Drury competed in science fairs at the national and international level with her research on the neurological systems of planaria worms under Petruska’s guidance.

In the team’s research into CD2AP, Drury recorded and analyzed changes in the nerve cells for the publication’s primary author, Ben Harrison, Ph.D., a postdoctoral fellow in the Department of Anatomical Sciences and Neurobiology and the article’s lead author. Drury, a high school sophomore at the time, was working in the lab as part of a self-directed learning program offered by her high school.

Drury recorded the length and number of branches in images of neural cells that had been treated with different amounts of CD2AP and those that were not treated to determine the protein’s effect on nerve growth.

“I put them into a program and I was able to trace them. The tracing allowed us to see whether they were growing more than they would normally,” Drury said.

“Cassie was the one who did measurements in the cultured neurons to determine that the protein was a positive regulator of growth,” Harrison said.

That work earned Drury a listing as fifth author on the publication, released in the April 13 edition of The Journal of Neuroscience. A total of 14 authors are credited on the article.

“It was not a gift,” Petruska said. “She did important work for this research and she understands what the work is about.”

Drury is eager to follow the research to which she has contributed.

“I am really interested to see where this research goes,” Drury said. “This connection is a really strong one and I am excited to see what comes out of it and what Ben ends up doing. I hope he can hand them a drug. That would be wonderful.”

This summer, Drury will be attending a science ethics leadership seminar at the University of Notre Dame on the ethical considerations of scientific research. After high school, she plans to study science in college, perhaps along with communications.

“One of the things that allowed Cassie to have such success in the science fair is that she is very good at communicating her results and her experiment design. She is good at answering questions,” Petruska said.

 

This work was supported by the CDRF International Consortium on Spinal Cord Injury Research, Kentucky Spinal Cord and Head Injury Research Trust Grant 09-12A, Paralyzed Veterans of America Fellowship, National Institutes of Health Grants P20RR016481, 3P20RR016481-09S1, P20GM103436, P30GM103507, R21NS080091, R21NS071299 and R01NS094741.

Nominations open for Gold Standard for Optimal Aging Award through Feb. 1, 2016

Nominations open for Gold Standard for Optimal Aging Award through Feb. 1, 2016

Dawne Gee, WAVE3

The Institute for Sustainable Health & Optimal Aging at the University of Louisville is seeking nominations for the 2016 Gold Standard for Optimal Aging Award. Nominations for this annual award are open now through Feb. 1, 2016.

The Gold Standard for Optimal Aging Award celebrates and honors older adults who embody the Institute’s vision for a world where all older adults lead engaged and flourishing lives. This award recognizes older adults who are 85 years or older and who are outstanding models of optimal aging in the following four categories: physical, social, spiritual and creative. There is no geographical limitation for nominations.

The award will be presented at a luncheon on May 10, 2016 at the Crowne Plaza, 830 Phillips Lane. WAVE3 News Anchor Dawne Gee will be the keynote speaker for this year’s award luncheon.

Lunch reservations are $35 per person and $350 for a table of 10. Sponsorships in a variety of opportunities also are currently being accepted by the Institute at (502) 852-5629.

Registration and nomination available at: louisville.edu/medicine/departments/familymedicine/geriatrics. For information, call 502-852-5629 or email OptimalAging@louisville.edu.

 

Youth justice system should be viewed through public health lens

Annual UofL pediatrics lecture to examine ‘Juvenile Justice Reform’ on Dec. 11
Youth justice system should be viewed through public health lens

Matthew Aalsma, Ph.D.

More than 65 percent of youth in the juvenile justice system in the United States meet the criteria for a disability, a rate three times higher than that of the general population. Research also shows that the more serious and prolonged a youth's interaction with the justice system becomes, the more likely he or she is to die prematurely.

Juvenile justice reform, therefore, is not only a law enforcement concern, it is a public health concern, said Matthew C. Aalsma, Ph.D., associate professor of pediatrics and psychology and director of the Juvenile Forensic Psychology Clinic at Indiana University.

Aalsma will deliver the 15th Annual Doctor Elliott Podoll Adolescent Medicine Lecture, sponsored by the University of Louisville Department of Pediatrics. The lecture will be at 8 a.m., Friday, Dec. 11, at Wade Mountz Auditorium, second floor of Norton Hospital, 200 E. Chestnut St. Admission is free.

Youth involved in the justice system “are a vulnerable population due to their high rates of mental illness, physical health problems and early mortality,” Aalsma said. “Juvenile justice reform that decreases the reliance on incarceration and improves behavioral health and medical services are very important public health initiatives.”

Trained as a pediatric psychologist, Aalsma focuses on research with vulnerable populations, including youth in the mental health and juvenile justice systems. His current research agenda includes exploring system-wide and individual efforts to improve the utilization of mental and physical health care for children and adolescents.

As director of the Juvenile Forensic Psychology Clinic, Aalsma oversees the provision of comprehensive psychologic assessments for court-involved youth. “The clinic provides thorough and fair assessments for vulnerable populations and trains psychology Ph.D. students in conducting juvenile forensic assessments,” he said.

The Podoll lectureship was established by the family of the late Elliott Podoll, M.D., a longtime Louisville pediatrician and clinical faculty member at the University of Louisville and a local pioneer in the provision of appropriate health care services for adolescents. The yearly lectureship brings an expert in the field of adolescent medicine to UofL in the spirit of what Podoll cared about: an increased awareness and development of the skills necessary to improve the lives of young people in the region.

For additional information, contact the UofL Department of Pediatrics at 502-852-8600.

 

More activities added to Cancer Awareness Show

Hillview event on May 21 benefits UofL’s James Graham Brown Cancer Center
More activities added to Cancer Awareness Show

The Horses and Hope pink Mustang will be on display May 21 at the Cancer Awareness Show at the Hillview Community Center, 298 Prairie Drive.

More activities have been added to the lineup of the Cancer Awareness Show, set for Saturday, May 21, from 11 a.m. to 5 p.m. at the Hillview Community Center, 298 Prairie Drive. Proceeds from the day’s activities will benefit research, community outreach and patient support programs of the James Graham Brown Cancer Center at the University of Louisville.

The Zoneton Fire Department will have its Fire Safety House for participants to walk through, and the Kentucky Cancer Program at UofL will display the pink Horses and Hope Mustang for breast cancer awareness.

Hobbies Café food truck also will be on hand, joining a variety of other vendors at the show, which has sold out its indoor booth spaces, said organizer Richard Luce Jr. Outdoor booth spaces remain available at $20 each.

The Cancer Awareness Show has something for the entire family with three shows-within-the-show: a model train show including 9X9, 4X16 and 3X6 layouts; an arts and crafts show; and “Cruizin’ for Cancer,” a car, truck and motorcycle show and a model car show.

The Zoneton Fire Department’s Fire Safety House is a walk-through model that helps teach children how to best respond to a house fire situation. The house is designed to provide a realistic environment for teaching basic fire prevention and survival skills. Kids learn about smoke detectors, how to determine escape routes from a fire in advance, and the importance of not hiding during a fire.

Former Kentucky First Lady Jane Beshear and the organization she founded, Horses and Hope, commissioned the pink Mustang from Paul Miller Ford for the 2011 NASCAR Sprint Cup race at the Kentucky Speedway. Since then, the Mustang tours the state to share life-saving breast cancer information. Horses and Hope works with the state’s equine industry to provide breast cancer education, screening and treatment referral.

Also included are prize and cash raffles. Representatives from Be The Match will be on hand to provide information about bone marrow donation. The James Graham Brown Cancer Center also will disseminate information on cancer prevention and treatment.

Admission is a cash donation to the James Graham Brown Cancer Center.

Liberty Tire and Recycling is a sponsor of the Cancer Awareness Show. The car, truck and motorcycle show is sponsored by the South Louisville Antique and Toy Mall and the model car show is sponsored by Dan’s Chips and Toys. Additional sponsorships for the show also are available: Platinum, $1,000; Gold, $500; Silver, $300; and Bronze, $100.

For information on vendors, sponsorships or the show, contact Luce at Bigscoby4@yahoo.com, CancerAwareness15@yahoo.com or 502-802-8308.

 

UofL resident physicians provide physicals and health screenings for Special Olympics athletes

Partnership with JCPS serves athletes and individuals with intellectual disabilities
UofL resident physicians provide physicals and health screenings for Special Olympics athletes

UofL PM&R medical residents and faculty at MedFest

More than 300 Special Olympics athletes and students from Jefferson and Bullitt Counties received free athletic physicals and health screening exams at University of Louisville’s Cardinal Stadium on Oct. 17. University of Louisville physical medicine and rehabilitation (PM&R) resident and faculty physicians provided the service as part of MedFest, an event organized by Special Olympics of Kentucky (SOKY) in partnership with Jefferson County Public Schools.

MedFest, part of the Special Olympics Healthy Athletes Initiative, is an annual event providing free pre-participation physicals for SOKY athletes and individuals with intellectual and developmental disabilities in the community age 8 through adult. The physicals are required for the athletes to compete in Special Olympics activities or unified track or bowling through the Kentucky High School Athletic Association.  Optional dental, vision and hearing screenings also are offered to the students and athletes.

<<CLICK TO WATCH A VIDEO OF THE EVENT

“It’s so important for our athletes to receive the medical screenings that they need. We know that through MedFest screenings, underlying conditions a lot of times are determined,” said Kim Satterwhite, senior director of field and athlete services for SOKY.

Priya Chandan, M.D., M.P.H., assistant professor in the UofL Division of Physical Medicine and Rehabilitation who serves as clinical director for the event, said participation in MedFest is not only a service to the community, but also a learning opportunity for the providers.

“Individuals with intellectual and developmental disabilities (IDD) experience health disparities, partly because many physicians in the community are not trained to provide care for them,” Chandan said. “It’s important for our trainees – medical residents and students, nurse practitioner and nursing students, and other providers – to have this opportunity to interact with this population.”

Maria Janakos, M.D., a resident physician in physical medicine and rehabilitation, was one of 10 UofL physicians who volunteered to provide pre-participation physical exams at this year’s event.

“The athletes are amazing individuals who have tremendous motivation and determination to succeed,” Janakos said. “It is rewarding to have the opportunity to interact with them. One of the individuals I met loves to play basketball. He told me his favorite athlete was LeBron James.”

MedFest has been held every year since 2005. The location alternates between Louisville and Lexington, however UofL PM&R physicians and trainees provide the screenings every year.

Dallas Derringer, one of the athletes at the event to obtain a physical for bowling, basketball and softball, expressed gratitude for the service:  “This physical is going to help me be ready!”

 

 

Nov. 20, 2018

Not your father’s tobacco: A scientist’s perspective on health risks of e-cigarettes

Beer with a Scientist, May 15
Not your father’s tobacco: A scientist’s perspective on health risks of e-cigarettes

Daniel Conklin, Ph.D.

What would you guess is the average age when someone starts smoking?

Perhaps early 20’s? Maybe even 16?

“The average chronic smoker begins smoking at 13.7 years old,” says Daniel Conklin, Ph.D. “And if you know anything about averages, that’s...not good.”

Conklin, a professor of medicine at the University of Louisville, specializes in cardiovascular research and what environmental pollutants do to our bodies. At this month’s Beer with a Scientist, Conklin will discuss smoking and what we do (and don’t) know about the harm caused by electronic cigarettes.

“Essentially, we’re trying to separate fact from fiction. We’re currently part of an American Heart Association Tobacco Regulation Center to investigate emerging tobacco products and their potential to cause harm to the cardiovascular system,” Conklin said. “We’re trying to figure out the best way to regulate these products.”

Scientists have known that conventional tobacco products are associated with cardiovascular disease risk since the 1960s, Conklin said. However, with new technology comes a new generation of health risks and the emerging science showing what vaping does to the body may shock you.

Conklin’s talk will begin at 7 p.m. on Wednesday, May 15, at Holsopple Brewing, 8023 Catherine Lane. A 30-minute presentation will be followed by an informal Q&A session.

Admission is free. Purchase of beer or other items is not required but is encouraged. Organizers encourage Beer with a Scientist patrons to drink responsibly.

UofL cancer researcher Levi Beverly, Ph.D., created the Beer with a Scientist program in 2014 as a way to bring science to the public in an informal setting. At these events, the public is invited to enjoy exactly what the title promises:  beer and science.

Setting the bar for heart, lung and blood research - UofL hosts second NIH institute director in three weeks

Setting the bar for heart, lung and blood research - UofL hosts second NIH institute director in three weeks

Gary H. Gibbons, M.D.

The National Heart, Lung and Blood Institute (NHLBI) of the National Institutes of Health (NIH) recently announced a strategic vision of eight objectives that provide the framework for the institute’s research priorities for the coming decade.

Gary H. Gibbons, M.D., director of the NHLBI, will discuss that vision in the 24th Leonard Leight Lecture at the University of Louisville on Friday, Nov. 4, at noon in the HSC Auditorium. In his talk, “Charting our future together:  Setting an agenda for the NHLBI,” Gibbons will outline the priorities set out in the vision, which support the NHLBI’s goals to understand and promote health, stimulate discoveries in the causes of disease, enable the translation of those discoveries into clinical practice and foster the next generation of scientists and physicians.

“The convergence of innovations in areas such as computational biology, data science, bioengineering and high-throughput ‘omics’ technologies is paving the way for a new appreciation of human health and disease,” Gibbons said as the institute published the NHLBI’s Strategic Vision in August. “We now have unprecedented opportunities to better understand the complex interplay of environmental, behavioral and molecular factors that promote health; a clearer picture of the earliest point of disease development; and the ability to repair damaged tissues with stem cell and tissue engineering techniques.”

The NHLBI provides global leadership for research, training and education programs to promote the prevention and treatment of heart, lung and blood diseases and enhance the health of all individuals so that they can live longer and more fulfilling lives.

The 24th Leonard Leight Lecture is scheduled for Friday, Nov. 4, 2016, noon - 1 p.m. in the HSC Auditorium in Kornhauser Library on the UofL Health Sciences Center Campus.

The Leonard Leight Lecture is presented by the Division of Cardiovascular Medicine in the Department of Medicine at the UofL School of Medicine. For 30 years until 1996, Leight was a practicing cardiologist in Louisville and played a major role in developing cardiology services and bringing innovative treatment modalities in heart disease to Louisville. The Leonard Leight Lecture series was established in 1994 and is made possible by gifts from Dr. and Mrs. Kurt Ackermann and Medical Center Cardiologists to the Jewish Hospital & St. Mary’s Foundation.

Gibbons is the second director of a National Institute to speak at UofL in three weeks. On Oct. 14, Linda S. Birnbaum, Ph.D., director of the National Institute of Environmental Health Sciences and the National Toxicology Program, discussed environmental research and the role of the NIEHS in human health at UofL as the keynote speaker of Research!Louisville.

Nominate a deserving medical resident for inaugural awards

Nominate a deserving medical resident for inaugural awards

Mark Amsbaugh, president, House Staff Council

The University of Louisville House Staff Council has launched the inaugural Outstanding Resident Awards to recognize achievement among the medical house staff.

Nominations are accepted through March 31, and anyone in the university community is eligible to submit a nomination. Three awards will be presented:

  • Resident of the Year Award: Presented to the resident who overall best embodies the mission of the university to provide excellent patient care, either directly or indirectly, advance his or her field through scholarly activity, educate other residents and students, and is an excellent example of professionalism.  
  • Resident with Outstanding Achievement in Scholarly Activity: Given to the resident who has achieved the most to further his or her field through scientific pursuit. Publications — both number and quality — as well as other scholarly activity such as presentations, quality improvement programs, grand rounds and others are considered.
  • Resident with Outstanding Achievement in Community Engagement: Awarded to the resident who has best embodied the university mission of service to and engagement with the community, state, nation or world.  A leadership role, over part or all of a project, is essential.

Nominations are made online  and must include the resident’s name and a 2-4-sentence description of the nominee’s qualifications for the award.  All nominations will be anonymous. Winners will be selected by the House Staff Council and will be announced in May or June.

For additional information, contact House Staff Council President Mark J. Amsbaugh, M.D., at mjamsb01@louisville.edu.

Improved DBS device offers a better solution for tremor

UofL, Jewish Hospital physicians first in region to offer refined DBS technology
Improved DBS device offers a better solution for tremor

Kathleen Prezocki with Joseph Neimat, M.D.

Kathleen Prezocki finally had enough.

Her essential tremor had progressed to the point that writing was nearly impossible, she always ordered sandwiches instead of soup or salad when eating out, and she was forced to use a card-holder so she could continue to play bridge.

“It was affecting me in eating, in writing and in speech. The medicine was not allowing me to control the symptoms anymore,” Prezocki said. “Trying to put a necklace on and trying to get that hook in there – my goodness that was frustrating!”

Prezocki’s UofL physicians suggested deep brain stimulation (DBS) therapy, in which surgeons implant in the brain a wire lead that is attached to a battery controller, similar to a pacemaker used for the heart. The lead provides electrical stimulation to a precise point in the brain to mitigate the tremor. DBS has been in use for nearly 20 years, but a new device allows more precise control over the stimulation, avoiding side effects, and is controlled with an iPod touch, a more intuitive control device than previous DBS technology.

The St. Jude Medical Infinity™ DBS system was recently approved by the U.S. Food and Drug Administration (FDA) for patients with Parkinson’s disease and essential tremor. The St. Jude system is the first in the United States to feature a directional lead designed to precisely customize therapy to help maximize patient outcomes and reduce side effects. The more precise control of the direction of the electrical stimulation allows for reduced strain on the battery, leading to longer battery life. In addition, the iPod Touch controller is more intuitive and familiar for patients.

When Prezocki learned of this improved DBS device, she decided it was time to take the next step, and was the first patient in the region to receive the St. Jude device. Joseph Neimat, M.D., a neurosurgeon with UofL Physicians, recently provided the implant for Prezocki at Jewish Hospital, part of KentuckyOne Health, to control tremor in her right hand. Neimat, also chair of the UofL Department of Neurological Surgery, has implanted several hundred DBS devices.

“This therapy can make a dramatic difference in a patient’s quality of life, particularly if they like to write, to play piano, to eat soup,” Neimat said. “And even though it is brain surgery, it’s a relatively low-risk surgery.”

Neurologist Victoria Holiday, M.D., clinical director of the Deep Brain Stimulation Program at UofL Physicians, has monitored Prezocki’s condition for several years and programmed her Infinity system to provide the proper stimulation. Holiday said the ability to more precisely control the stimulation allows doctors to achieve stimulation in the desired location while avoiding side effects.

“Think about a wire inside the brain and electricity is surrounding that wire in a ball shape. With this device, we can cut that ball into pie pieces. It allows us to steer away from areas of the brain that may be causing trouble,” said Holiday, also an assistant professor in the UofL Department of Neurology.

Since activating the device, Prezocki has been able to stop taking tremor medications. Her ability to write is improved and she is able to play bridge without a card-holder.

“I can write again!” Prezocki said.

“Her handwriting is much better than expected. Ms. Prezocki was not able to write at all prior to surgery and is now scrutinizing how her Zs look,” Holiday said. “She is successfully using the patient programmer at home and seems very pleased with how the system works.”

3D model of child’s heart helps surgeons save life

See video interviews with the faculty who made it happen here.

A 14-month-old boy in need of life-saving heart surgery is the beneficiary of a collaboration among University of Louisville engineers, physicians and Kosair Children’s Hospital.

Roland Lian Cung Bawi of Owensboro was born with four congenital heart defects and his doctors were looking for greater insights into his condition prior to a Feb. 10 operation.

Dr. Philip Dydynski, chief of radiology at Kosair Children’s Hospital, recently had toured the Rapid Prototyping Center at the University of Louisville’s J.B. Speed School of Engineering and became impressed with the 3D printing capabilities available there.

He asked the center’s operations manager, Tim Gornet, if a 3D model of the child’s heart could be constructed using a template created by images from a CT scan to allow doctors to better plan and prepare for his surgery. No problem, Gornet said.

The result of the Rapid Prototyping Center’s work was a model heart 1.5 times the size of the child’s. It was built in three pieces using a flexible filament and required about 20 machine hours – and only about $600 -- to make, Gornet said.

Once the model was built, Dr. Erle Austin III, cardiothoracic surgeon with University of Louisville Physicians, was able to develop a surgical plan and complete the heart repair with only one operation.

“I found the model to be a game changer in planning to do surgery on a complex congenital heart defect,” he said.

Roland was released from Kosair Children’s Hospital Feb. 14 and returned Feb. 21 for checkups with his doctors. His prognosis is good.

That’s good news for Gornet, whose work at the Rapid Prototyping Center routinely benefits manufacturers and heavy industry. Helping surgeons save a life was new territory for him.

“Knowing we can make somebody’s life better is exciting,” he said.

Lung cancer breath ‘signature’ presents promise for earlier diagnosis

UofL researchers’ analysis of breath samples could lead way to increased survival
Lung cancer breath ‘signature’ presents promise for earlier diagnosis

The balloon device and microchip used by the researchers are shown.

A single breath may be all it takes to identify the return of lung cancer after surgery, according to a study authored by University of Louisville Researchers and posted online today by The Annals of Thoracic Surgery.

Exhaled breath contains thousands of volatile organic compounds (VOCs) that vary in composition and pattern depending on a person’s health status. A subset of four VOCs—called carbonyl compounds because of their carbon base—have been discovered in the exhaled breath of lung cancer patients. Being able to identify this lung cancer “signature” through a simple breath test has emerged as one of the most promising ways to diagnose the disease. Now the test is being used to monitor for disease recurrence.

Erin M. Schumer, M.D., of the Department of Surgery, Victor van Berkel, M.D., Ph.D., of the Department of Cardiovascular and Thoracic Surgery and colleagues from the University of Louisville analyzed breath samples collected before and after surgery from 31 lung cancer patients and compared their carbonyl VOCs levels with samples from 187 healthy patients.

The researchers found a significant decrease in overall carbonyl VOC levels following surgery; in fact, three of the four carbonyl VOCs normalized after surgery, matching levels in the control group.

“The rapid normalization of almost all of the four compounds after surgery provides strong evidence that they are directly produced by the tumor environment,” Schumer said. “This study confirms that the technology is accurate.”

Lung cancer is the leading cause of cancer death. The American Cancer Society estimates that more than 224,000 Americans will be diagnosed with lung cancer this year, and more than 158,000 lung cancer patients will die—that translates to 433 lung cancer deaths per day in the United States.

Schumer said those grim statistics underscore the need for early detection, “We hope that breath analysis will allow us to diagnose patients with primary or recurrent lung cancer long before they suffer from symptoms, when we have more options for treating them, giving them the best chance for cure.”

Currently, lung cancer patients are followed after surgery with chest computed tomography (CT) scans, which can be inconvenient, expensive, and expose the patient to radiation. “We hope that the breath analysis can serve as the primary screening tool for cancer recurrence and a CT scan ordered only if the breath test suggests that there has been a change,” van Berkel said.

How the breath test works

The process of breath analysis is relatively simple. The patient blows a single breath into a specialized balloon. The balloon is then connected to a pump that pulls the breath over a small microchip that is smaller in size than a quarter, trapping the chemicals. The microchip is sent to the lab, where the chemicals are analyzed within hours. Breath collection can be performed in the doctor’s office.

The pump is reusable; the balloon, microchip and lab test together cost around $20, all supporting the increasing acceptance of breath tests as a cost-effective, easy-to-perform, non-invasive and rapid option for the diagnosis of lung cancer.

“The great potential with breath analysis is detecting lung cancer at any point, both as a primary screening tool and to follow patients after disease has been treated,” van Berkel said. “The technology is pretty robust. Our next step is getting approval from the FDA.”

 

Daniel A. Durbin named associate vice president for health affairs at UofL

Daniel A. Durbin named associate vice president for health affairs at UofL

Daniel A. Durbin

Daniel A. Durbin has been named associate vice president for health affairs/chief financial officer for the University of Louisville Health Sciences Center. The appointment is pending approval from the UofL Board of Trustees.

Durbin currently is the senior associate vice president for administration and finance at West Virginia University.

Gregory C. Postel, M.D., UofL interim president and interim executive vice president for health affairs, highlighted Durbin’s extensive experience within academic medicine and higher education.

“Dan brings to Louisville more than 30 years’ experience with the finances at universities and academic health centers,” Postel said. “During this significant time of transition for UofL and our health sciences center, this expertise is invaluable.”

Durbin joined the WVU Division of Finance in 2006. He maintains overall responsibility for central finance functions comprising more than 140 staff members in areas including institutional accounting, budget planning, procurement, payment services, revenue services, risk management, grants accounting, payroll and financial compliance. Durbin also serves as the treasurer for the WVU Research Corporation and the WVU Innovation Corporation. Before joining the finance division, he held financial and administrative leadership positions at the WVU Health Sciences Center for nearly 20 years, ultimately becoming its director of budget and financial operations.

Durbin serves as a Peer Reviewer with the Higher Learning Commission. He also is a member of the National Association of College and University Business Officers, as well as the Southern Association of College and University Business Officers.

He earned his bachelor’s degree in accounting and finance from Glenville State College in Glenville, W.Va., and his master’s in public administration from West Virginia University.

UofL resident physician to deliver research at national ophthalmology conference

UofL resident physician to deliver research at national ophthalmology conference

Joshua C. Gross, M.D.

Joshua C. Gross, M.D., a first-year resident in training with the UofL Department of Ophthalmology and Visual Sciences, will present his research at the annual meeting of the Association of University Professors of Ophthalmology (AUPO) on Jan. 26 in Austin, Tex. At the RPB/AUPO Resident and Fellow Research Forum. Gross has conducted research into the association between blood flow in the retina and the progression of open-angle glaucoma and diabetes mellitus.

Working with colleagues at Indiana University School of Medicine and in Italy, Gross found that patients who had reduced retinal blood flow and optic nerve damage consistent with glaucoma who also had diabetes experienced faster visual deterioration than patients with similar characteristics but who did not have diabetes.

Open-angle glaucoma, the most common form of glaucoma, accounts for at least 90 percent of all glaucoma cases, affecting about 3 million Americans. It is caused by the slow clogging of the drainage canals, resulting in increased eye pressure. 



January 25, 2018

Surplus medical equipment from UofL gets a second life in Ghana

Improvements in eye care at UofL mean better care for 3 million Africans
Surplus medical equipment from UofL gets a second life in Ghana

Surplus ophthalmic equipment in use in Tamale, Ghana

To provide the best care for patients and the best training for physicians, the University of Louisville Department of Ophthalmology and Visual Sciences and UofL Physicians Eye Specialists regularly upgrade diagnostic and other equipment. Several of these displaced items have been put to use more than 5,000 miles away to improve care for patients in Ghana.

Until recently, Friends Eye Center in Tamale, Ghana, lacked basic ophthalmic equipment and the center’s surgical microscope was outdated and cumbersome. The center, directed by Seth Wanye, M.D., provides vision care for nearly 3 million residents of the West African nation and serves as a training site for future ophthalmologists.

Henry J. Kaplan, M.D., chair of the UofL Department of Ophthalmology and Visual Sciences, visited Friends Eye Center during a medical mission trip several years ago.

“Most of the equipment they had was non-functional. The equipment we gave them we no longer use because of the acquisition of more technologically advanced diagnostic devices,” Kaplan said. “Many of the people there have totally lost their eyesight and are dependent on their relatives and other support structures, which presents an enormous economic burden.”

Wanye, who regularly visits UofL to enhance his surgical skills, was visiting Louisville in 2015 when Kaplan offered to donate the equipment to his center in Ghana.

“It was like a dream come true,” Wanye said. “It helps me perform thorough examinations of the eye so I can identify other problems, not just the cataract that you can see. It also gives the patients comfort and they are fascinated.”

Shipping large items to Africa is not a simple process, however, and it was nearly a year before the equipment reached the center. Thanks to multiple organizations that shared the expense and worked to transport the instruments, the Friends Eye Center now has a slit lamp, which allows Wanye to examine his patients’ eyes more precisely, a better surgical microscope, chairs for both the surgeon and the patient, and an auto refractor for determining eyeglass prescriptions.

Wanye, who was the only ophthalmologist serving the Northern and Upper West regions of Ghana until a colleague joined him last year, also works with future physicians in the center to introduce them to the specialty of ophthalmology. Most Ghanaian medical students choose other specialties since ophthalmology is not a medical priority in Ghana.

“You have so many other diseases that are killing people. They say eye diseases don’t kill so they are overlooked,” Wanye said. But he has seen that restoring vision allows individuals to regain their independence and enables children to go back to school.

“When you go out into the villages, people are poor, they don’t have money but they are blind. So we will get the resources and do the surgery.”

Wanye receives funding from non-governmental organizations (NGOs) such as Unite for Sight and the Lions Clubs International to provide eye screenings and perform between 2,000 and 4,000 cataract surgeries each year. In addition to screenings and surgeries on location, Wanye provides care for patients in the Friends Eye Center.

“To be one doctor that serves millions of people is not a trivial task. He does it because of a love and conviction for the good that he is doing. I really do admire what he’s doing and that’s why we are more than happy to assist him,” Kaplan said. This is the first time UofL’s ophthalmology department has donated equipment to a foreign health-care organization.

Wanye hopes to establish a regular exchange between UofL ophthalmologists and the center, similar to a program in which residents and faculty members from the UofL Department of Pediatrics travel to the Tamale Teaching Hospital several times each year. Tamale is an official sister city to Louisville.

“My dream is to have some continuous program, especially with the residents’ program here, so we would have residents coming to Friends Eye Center,” Wanye said. In the meantime, he is grateful to UofL for the donated equipment. “We know how valuable they are and how expensive they are. They will help us deliver more quality service to our people. Thank you to everyone at UofL,” Wanye said.

 

February 6, 2017

Photo courtesy Friends Eye Center, Ghana

UofL medical student wins essay contest for perspective on patients with mental illness

UofL medical student wins essay contest for perspective on patients with mental illness

Natalie Spiller

Natalie Spiller, a fourth-year student at the University of Louisville School of Medicine, believes patients with mental health disorders need a physician’s empathy, compassion and best medical attention. In her experience, they do not always receive it.

Spiller’s essay on the topic won the Physician-in-Training/Student category in the eighth annual Richard Spear, M.D., Memorial Essay Contest, sponsored by the Greater Louisville Medical Society. This year’s theme was:  “What Drives you Crazy in Health Care?”

In her essay, Spiller calls attention to discrimination shown by health-care professionals toward patients with mental health disorders. Spiller opens her piece by describing a situation in which a woman arrives alone in an emergency room with incoherent speech and disheveled appearance, along with a history of drug abuse and mental illness. While the physician-narrator assumes her symptoms were due to drugs or mental illness, it turns out the woman is suffering from a stroke. The patient dies.

“While our society is making its way to de-stigmatize the diagnosis of mental health disorders, we in the medical community have a long way to go in creating comprehensive medical care for those suffering from ‘invisible illness,’” Spiller wrote.

For the winning essay, published in the July issue of Louisville Medicine, Spiller received a plaque and $750 award at the 2017 GLMS Presidents’ Celebration in May.

The awards are named for Richard Spear, a respected Louisville general surgeon who also served on the faculty of the UofL School of Medicine. When he died in 2007, Spear left GLMS a bequest to fund the annual essay contest. Spear wished to support high quality writing about the practice of medicine.

 

Photo courtesy GLMS.

August 11, 2017

Spike it to Cancer sand volleyball event benefits UofL cancer center, Aug. 12

Spike it to Cancer sand volleyball event benefits UofL cancer center, Aug. 12

2016 Spike it to Cancer tournament

Benefactors of a fund to support patients at the University of Louisville James Graham Brown Cancer Center are sponsoring their fifth annual sand volleyball event to raise money for the fund.

The Mary Jane Gift Quality of Life Fund was established in 2013 by Alex and Tommy Gift in honor of their late mother, who passed away from breast cancer in 2010. The fund helps patients and their families enjoy life while facing a cancer diagnosis. For the past four years, the fund has provided Thanksgiving turkeys for patients at the cancer center.

To benefit the fund, the Gifts are sponsoring the Fifth Annual Spike it to Cancer Sand Volleyball Tournament at Baxter Jack’s sand volleyball complex, 427 Baxter Ave. on Saturday, Aug. 12. Player or spectator admission is $20 per person. The Open Pro division (co-ed quads) play starts at 8 a.m. (check in at 7:30 a.m.). The Fun division (co-ed sixes) play will start at about 2 p.m. (check in at 1:30 p.m.).  

To register a team, purchase admission or make a donation, go to the event’s online link. All registration fees go directly to the fund. Last year’s event raised $13,466 for the fund.

Additionally, Ward 426 on Baxter Ave., directly across the street from Baxter Jack’s, has once again agreed to donate a portion of all food and beverage sales throughout the day to the fund.

“Mary Jane taught us countless lessons throughout the course of her life. Stay Positive. Be thankful. Step away from it all,” Alex Gift said. “The fund can help do this by providing simple gifts to patients that could help improve their quality of life, even if it’s for a short period of time.”

The event has brought in more than $45,000 over five years.

For additional details, contact Lisa Ward at 502-852-2794.

Three siblings pursue dreams at UofL School of Medicine

Youngest member of the Eid family joins her brothers in medical school at white coat ceremony July 26
Three siblings pursue dreams at UofL School of Medicine

Eid family - Ryan, Nemr, Sabine, Nada and Mark

When Nemr Eid, M.D., joined the staff at the University of Louisville School of Medicine in 1988, he could not have guessed that his children would ultimately attend medical school there – all at the same time. As of July 26, when Eid’s youngest child, Sabine, received her white coat and formally became a medical student, all three children of Eid and his wife, Nada, are students in the UofL School of Medicine.

“When I think about it, it fills my heart with joy and with pride,” said Eid, chief of UofL’s division of pediatric pulmonology. “And to have them in the same medical school with me is even more joyful.”

At the White Coat Ceremony, held on July 26 at the Downtown Marriott (280 W. Jefferson), the UofL School of Medicine faculty and medical community members formally welcomed first-year medical students by presenting them with a white coat. The coats, a gift from the Greater Louisville Medical Society, are shorter than the physicians’ coats, and are worn until the student graduates from medical school. Once they received their coats, members of the incoming class recited the Declaration of Geneva, promising to serve humanity and honor the traditions of the medical profession.

Eid never assumed his children would follow in his footsteps. He encouraged them to pursue their own paths.

“We would sit at the dinner table and talk about what you want to be. I did not discourage them. I did not say ‘you should not be a doctor.’ But I never encouraged them, either,” Eid said. “I would tell them to ‘follow your dream; do whatever makes you happy.’ I never thought all three of them would go into medicine!”

Eid’s three children, Mark, Ryan and Sabine, each decided on a career in medicine via different routes. The eldest, Mark, originally set his sights on a career in economics or law. Sabine considered a career in broadcast communications. Only the middle child, Ryan, always knew he wanted to be a physician.

“I knew I would go into medicine since the third grade. Science was one of my passions,” Ryan said. “I also have always been interested in cultures and people and the world and travel. That took me to the University of Miami in Florida. It is the most diverse school in the country, so I have friends in China, the Cayman Islands, Europe and Africa.”

Mark enrolled as an undergraduate at UofL with a law degree in mind.

“I was a political science and economics major for my first two and a half years of college,” Mark said. However, he realized he missed science and appreciated his father’s relationships with his patients. So he backtracked to catch up on undergraduate science courses in preparation for medical school.

In 2013, both Mark and Ryan enrolled at UofL School of Medicine as members of the class of 2017.

Having also decided on a career in medicine, Sabine received her bachelor’s degree from UofL this spring with a major in biology, and will formally join her brothers in medical school as a member of the Class of 2019.

“I had the privilege of working with Dr. Nemr Eid on mutual patients with pediatric airway problems for many years. It has been such a treat to have his sons, Mark and Ryan, as medical students at UofL. Their strong intellect, commitment and altruistic spirit certainly came as no surprise,” said Toni Ganzel, dean of the UofL School of Medicine. “I’m delighted to see the Eid legacy continue at UofL and look forward to working with Sabine as she begins her medical school journey.”

Although they had individual mentors outside the family, each of the Eid children say their father inspired them to enter medicine through his attitude toward his work.

“He gets up every single morning and goes to work happy,” Sabine said. “He comes home every single evening happy. He loves what he does. He has never said anything negative. Hopefully, in the chapter I choose, I will wake up every morning and feel excited to go to work.”

They also credit their mother, Nada, for encouragement and support.

“She is a lawyer so she knows exactly what a rigorous curriculum is like. My mom has been there to help us through the tasks at hand from grade school and college and now med school,” Ryan said.

“Each of them has had a different journey that brought them to this day,” Dr. Eid said. “Each will have a different path that will propel them to their dream. It is up to them to follow that dream.”

 

About Pediatric Pulmonology – During his first ten years at UofL, Nemr Eid, M.D., was the only pediatric pulmonologist in Louisville. Although other physicians in his specialty now have joined him, a critical need for these physicians remains throughout the nation and in Kentucky, where there is only one pediatric pulmonologist for every 170,000 children. Under Eid’s direction, UofL began a pediatric pulmonology fellowship two years ago, but he hopes more physicians will pursue the specialty since those positions are not always filled.

Conference to examine multidisciplinary approach to treating metastatic brain and spinal cancer

UofL James Graham Brown Center hosts meeting July 10 open to providers and public

Experts from around the country will join faculty experts from the University of Louisville’s James Graham Brown Cancer Center, a part of KentuckyOne Health, to look at the latest evidence-based medicine in treating metastatic cancer of the central nervous system.

“Evaluation and Management of Patients with Brain and Spinal Metastasis” will be held July 10 from 7:15 a.m. to 12:30 p.m. at the UofL Clinical and Translational Research Building, 505 S. Hancock St. Admission is free but pre-registration is strongly encouraged at the conference website.

“We are bringing together some of the leading clinicians and researchers from our cancer center and beyond to discuss the latest innovations in caring for patients with central nervous system cancer,” said Conference Director Eric Burton, M.D., assistant professor in the Department of Neurology. “Disciplines represented include neurosurgery, radiation oncology, neuroradiology, neuro-oncology and more.”

The conference is designed both for health care providers and the general public, Burton said. “If you are a health care professional working in the neurological cancer field, if you are a patient with neurological cancer or if you are a caregiver to someone with neurological cancer, this conference will benefit you.”

In addition to Burton, presenters include:

 

  • Donald Miller, M.D., Ph.D., director, James Graham Brown Cancer Center, and James Graham Brown Foundation Chair, UofL
  • Michael Glantz, M.D., professor of neurosurgery, medicine and neurology, Penn State University
  • Roy Patchell, M.D., neurologist, Capital Health Medical Center-Hopewell and Capital Institute for Neurosciences, Pennington, N.J.
  • Warren Boling, M.D., interim chair and professor, Department of Neurological Surgery, UofL
  • Vinai Gondi, M.D., clinical assistant professor, University of Wisconsin Comprehensive Cancer Center and Radiation Oncology Consultants, Chicago
  • Maxwell Boakye, M.D., associate professor and the Ole A., Mabel Wise and Wilma Wise Nelson Chair in Clinical Geriatrics Research, UofL Department of Neurological Surgery
  • Shaio Woo, M.D., chair and professor, Department of Radiation Oncology, and the Kosair Children’s Hospital/Norton Healthcare Chair in Pediatric Oncology, UofL
  •  

    Continuing education credit is available to health care providers. For additional information, visit the conference website or contact Emily Rollins in the UofL Department of Neurological Surgery at emily.rollins@louisvilleneuroscience.com.

    Scientists meet in Louisville to share research that could lead to improved treatments for spinal cord and head injury

    Scientists meet in Louisville to share research that could lead to improved treatments for spinal cord and head injury

    The second participant to receive an epidural stimulator as part of the investigation of standing, stepping and voluntary control in individuals with complete spinal cord injury.

    More than a dozen leading basic scientists from around the nation and the world studying neurological function will make presentations to 160 fellow researchers in Louisville Wednesday and Thursday. The goal is to facilitate collaborations that will advance science leading to improved spinal cord and head injury rehabilitation.

    Scientists from Sweden, Canada and the United States will share their latest neurotrauma research at the 21st Annual Kentucky Spinal Cord & Head Injury Research Trust Symposium.

    The symposium, sponsored by Kentucky Spinal Cord and Head Injury Research Trust, Kentucky Spinal Cord Injury Research Center, KentuckyOne Health, Craig H. Neilsen Foundation and University of Louisville School of Medicine, is organized to advance the study of neurotrauma and ultimately lead to methods of restoring function to those with spinal cord and head injuries.

    Among those speaking are Abdel El Manira, Ph.D., and Tatiana Deliagina, Ph.D., of the Karolinska Institute in Sweden, and Paul Kubes, Ph.D. and Christopher Power, M.D., F.R.C.P.C. of Canada. El Manira will discuss his research into locomotor circuits in zebrafish. His research shows that neuron groups are selectively wired for slow, intermediate or fast movement, and the fish’s nervous system selects distinct motoneurons for different swimming speeds.

    Deliagina will discuss her work studying feedback mode of postural control in quadrupeds. Loss of postural control is one of the major motor disorders following spinal cord injury. Marc Freeman, Ph.D. of the University of Massachusetts Medical School will present the keynote address on the cellular and molecular mechanisms of nerve degeneration.

    This work is similar to basic science research that led to the groundbreaking clinical studies, done at the University of Louisville and Frazier Rehab Institute, in which stimulators were transplanted into spinal cord injured patients who subsequently gained the ability for volitional movement in their legs (see the patient photo below).

    The event will be held May 20-21, 2015 at the Louisville Marriott Downtown, 280 W. Jefferson St. Hours are 8 a.m. - 5 p.m. Wednesday and 8 a.m. - 3:30 p.m. Thursday.

    The UofL Kentucky Spinal Cord Injury Research Center is dedicated to developing successful spinal cord repair strategies in the laboratory that can be taken to the clinic in a timely and responsible fashion.