Andrew M. Roberts, Ph.D.


amrobe01@louisville.edu
Associate Professor
New York Medical College, 1980

Cardiopulmonary Physiology My general area of research is neural control mechanisms involved in the regulation of the cardiovascular and pulmonary systems. Studies include investigation of afferent properties and reflex roles of sensory nerves in the heart and lungs and involve examination of cardiovascular and respiratory responses. Research activities include studies of the neural control of the microcirculation with emphasis on responses caused by interaction of local factors with neural mechanisms. Other studies involve investigation of endothelial mechanisms of pulmonary microvascular control and changes that occur during pathophysiological circumstances such as acute respiratory distress syndrome, occlusion-reperfusion injury and pulmonary hypertension.

Recent Publications

  1. Liu R., R.A. Vaishnav, A.M. Roberts, and R.P. Friedland. Parkinson's Disease, edible solanaceae and tobacco mosaic virus. Ann Neurol. 75(1):p.162-3, 2014. doi:10.1002/ana.24041. PMID: 24123107.
  2. Angle, J.R., E.A. Prince, A.H. Matsumoto, T.E. Lohmeier, A.M. Roberts, S. Misra, M.K. Razavi, R.E., R.E.  Katholi, S. N. Sarin, D.A. Sica, K. Shivkumar, and K. Ahrar.  Proceedings from the Society of Interventional Radiology Foundation Research Consensus Panel on Renal Sympathetic Denervation.  J Vasc Interv Radiol,  25: 497-509, 2014.  http://dx.doi.org/10.1016/j.jvir.2013.12.572.
  3. Roberts, A.M., J. Yu and I.G. Joshua.  Microvascular dilation evoked by chemical stimulation of C-fibers in rats.  J  Appl Physiol 118:55-60, 2015; doi 10.1152/japplphysiol.00077.2014.
  4. Roberts AM, Jagadapillai R, Vaishnav RA, Friedland RP, Drinovac R, Lin X, and Gozal E.  Increased pulmonary arteriolar tone associated with lung oxidative stress and nitric oxide in a mouse model of Alzheimer’s disease.  Physiol. Rep. 4(17), 2016; e12953, doi:10.14814/Phy2.12953.
  5. Chen SG, Stribinskis V, Rane MJ, Demuth DR, Gozal E, Roberts AM, Jagadapillai R, Liu R, Choe K, Shivakumar B, Son F, Jin S, Kerber R, Adame A, Masliah E, and Friedland RP.  Exposure to the functional bacterial amyloid protein curli  enhances alpha-synuclein aggregation in aged Fischer 344 Rats and C aenorhabditis Elegans. Scientific Reports-  NatureSci .Rep. 6, 34477; doi:10.1038/srep 34477, 2016. 
  6. Jagadapillai R,  Rane MJ, Lin X, Roberts AM, Hoyle GW, Cai L and Gozal E.  Diabetic  microvascular disease and pulmonary fibrosis.  Int. J. Mol. Sci. 2016 Nov; 17(11): 1853.  Doi:10.3390/ijms 17111853.
  7.  Musah S, Schlueter CF, Humphrey DM Jr, Powel, KS, Roberts AM, and Hoyle GW.  Acute lung injury and persistent small airway disease in a rabbit model of chlorine inhalation.  Toxicology and Applied  Pharmacology 315 (2017) 1-11.  http//dx.doi.org/10.1016/j.taap.2016.11.017
  8. Carll, A.P., Farraj, A. K., and Roberts, A. M. (2018) The Role of the Autonomic Nervous System in Cardiovascular Toxicology. In: McQueen, C. A., Comprehensive Toxicolog,Third Edition. Vol 13, pp. 61-114. Oxford: Elsevier Ltd. ISBN: 9780081006016