Betty C. Villafuerte, M.D.

Betty C. Villafuerte, M.D.

Betty C. Villafuerte, M.D.

  • Associate Professor of Medicine
UofL Physicians Outpatient Center
401 East Chestnut Street, Ste. 310
Louisville, KY 40202

502-588-4600 - Patient Appointments
502-852-5237 - Academic Office

Clinical Expertise
Diabetes; Obesity; Hypoglycemia; General Endocrinology

Board Certifications

  • American Board of Internal Medicine -
    Internal Medicine / Endocrinology, Diabetes and Metabolism

Education and Training

  • Medical School: University of the Philippines
  • Residency: Buffalo General Medical Center
  • Fellowship: Emory University

Featured Publications

  • Villafuerte BC, Barati MT, Rane MJ, Isaacs S, Li M, Wilkey DW, Merchant ML. Over-expression of insulin-response element binding protein-1 (IRE-BP1) in mouse pancreatic islets increases expression of RACK1 and TCTP: Beta cell markers of high glucose sensitivity. Biochim Biophys Acta Proteins Proteom. 2017 Feb;1865(2):186-194. doi: 10.1016/j.bbapap.2016.10.015. Epub 2016 Nov 3. PubMed PMID: 27816562; PubMed Central PMCID: PMC5233416.
  • Moore JP Jr, Villafuerte BC, Unick CA, Winters SJ. Developmental changes in pituitary adenylate cyclase activating polypeptide expression during the perinatal period: possible role in fetal gonadotroph regulation. Endocrinology. 2009 Oct;150(10):4802-9. doi: 10.1210/en.2008-1649. Epub 2009 Jul 2. PubMed PMID: 19574403; PubMed Central PMCID: PMC2754687.
  • Villafuerte BC, Barati MT, Song Y, Moore JP, Epstein PN, Portillo J. Transgenic expression of insulin-response element binding protein-1 in beta-cells reproduces type 2 diabetes. Endocrinology. 2009 Jun;150(6):2611-7. doi: 10.1210/en.2008-1294. Epub 2009 Feb 12. PubMed PMID: 19213832; PubMed Central PMCID: PMC2689803.
  • Maudar V, Winters SJ, Villafuerte BC. Hot flashes and fatigue relieved by metformin. Endocr Pract. 2009 Jan-Feb;15(1):30-4. PubMed PMID: 19211394.
  • Chahal J, Chen CC, Rane MJ, Moore JP, Barati MT, Song Y, Villafuerte BC. Regulation of insulin-response element binding protein-1 in obesity and diabetes: potential role in impaired insulin-induced gene transcription. Endocrinology. 2008 Oct;149(10):4829-36. doi: 10.1210/en.2007-1693. Epub 2008 Jun 19. PubMed PMID: 18566119; PubMed Central PMCID: PMC2582919.
  • Villafuerte BC, Kaytor EN. An insulin-response element-binding protein that ameliorates hyperglycemia in diabetes. J Biol Chem. 2005 May 20;280(20):20010-20. Epub 2005 Mar 7. PubMed PMID: 15753094.
  • Villafuerte BC, Phillips LS, Rane MJ, Zhao W. Insulin-response element-binding protein 1: a novel Akt substrate involved in transcriptional action of insulin. J Biol Chem. 2004 Aug 27;279(35):36650-9. Epub 2004 Jun 11. PubMed PMID: 15194686.