Vivek R. Sharma, M.D., FACP

Vivek R. Sharma, M.D.

Vivek R. Sharma, M.D., FACP

  • Associate Professor of Medicine
  • Director, Adult Hemophilia Program
  • Director, Medical Oncology Service, GI Cancer Multidisciplinary Clinic
UofL James Graham Brown Cancer Center
529 South Jackson Street
Louisville, KY 40202

502-852-2522 - Academic Office
502-562-4370 - Patient Appointments


Clinical Expertise
Medical Oncology - Gastrointestinal; Hemophilia and Other Benign Hematology


Board Certifications

  • American Board of Internal Medicine -
    Internal Medicine / Medical Oncology / Hematology

Education and Training

  • Medical School: B.J. Medical College, University of Poona
  • Residency: University of Louisville Hospital
  • Fellowship: University of Louisville

Featured Publications

  • Sharma VR, Thomas SD, Miller DM, Rezzoug F. Nucleolin Overexpression Confers Increased Sensitivity to the Anti-Nucleolin Aptamer, AS1411. Cancer Invest. 2018;36(9-10):475-491. doi: 10.1080/07357907.2018.1527930. Epub 2018 Nov 5. PubMed PMID: 30396283; PubMed Central PMCID: PMC6396827.
  • Martin RC 2nd, Scoggins CR, Schreeder M, Rilling WS, Laing CJ, Tatum CM, Kelly LR, Garcia-Monaco RD, Sharma VR, Crocenzi TS, Strasberg SM. Randomized controlled trial of irinotecan drug-eluting beads with simultaneous FOLFOX and bevacizumab for patients with unresectable colorectal liver-limited metastasis. Cancer. 2015 Oct 15;121(20):3649-58. doi: 10.1002/cncr.29534. Epub 2015 Jul 6. PubMed PMID: 26149602.
  • Claudino WM, Dias A, Tse W, Sharma VR. Type B lactic acidosis: a rare but life threatening hematologic emergency. A case illustration and brief review. Am J Blood Res. 2015 Jun 15;5(1):25-9. eCollection 2015. PubMed PMID: 26171281; PubMed Central PMCID: PMC4497494.
  • Recht M, Neufeld EJ, Sharma VR, Solem CT, Pickard AS, Gut RZ, Cooper DL. Impact of acute bleeding on daily activities of patients with congenital hemophilia with inhibitors and their caregivers and families: observations from the Dosing Observational Study in Hemophilia (DOSE). Value Health. 2014 Sep;17(6):744-8. doi: 10.1016/j.jval.2014.07.003. Epub 2014 Aug 14. PubMed PMID: 25236999.
  • Sharma VR. Paroxysmal nocturnal hemoglobinuria: pathogenesis, testing, and diagnosis. Clin Adv Hematol Oncol. 2013 Sep;11 Suppl 13(9):2-8. PubMed PMID: 25856267.
  • Bhatt G, Li XF, Jain A, Sharma VR, Pan J, Rai A, Rai SN, Civelek AC. The normal variant (18)F FDG uptake in the lower thoracic spinal cord segments in cancer patients without CNS malignancy. Am J Nucl Med Mol Imaging. 2013 Jul 10;3(4):317-25. Print 2013. PubMed PMID: 23901357; PubMed Central PMCID: PMC3715776.
  • Golub DV, Civelek AC, Sharma VR. A regimen of taxol, Ifosfamide, and platinum for recurrent advanced squamous cell cancer of the anal canal. Chemother Res Pract. 2011;2011:163736. doi: 10.1155/2011/163736. Epub 2011 Jun 15. PubMed PMID: 22295202; PubMed Central PMCID: PMC3265251.
  • Kang KA, Ren Y, Sharma VR, Peiper SC. Near real-time immuno-optical sensor for diagnosing single point mutation: a model system: sensor for factor V Leiden diagnosis. Biosens Bioelectron. 2009 May 15;24(9):2785-90. doi: 10.1016/j.bios.2009.02.004. Epub 2009 Feb 20. PubMed PMID: 19318242; PubMed Central PMCID: PMC2718714.
  • Sharma VR, Brannon MA, Carloss EA. Effect of omeprazole on oral iron replacement in patients with iron deficiency anemia. South Med J. 2004 Sep;97(9):887-9. PubMed PMID: 15455980.
  • Moffett PU, Feng Y, Sharma VR. Measuring prothrombin time: too long may be too short! Am J Hematol. 2004 Mar;75(3):177-8. PubMed PMID: 14978702.