Jesse Roman, M.D., FACP, FACCP

Jesse Roman, M.D., FACP, FACCP

Jesse Roman, M.D., FACCP, FACP

Jesse Roman, M.D., FACP, FACCP

  • Professor of Medicine, Pharmacology and Toxicology
  • Chairman, Department of Medicine
  • Chief, Division of Pulmonary, Critical Care & Sleep Disorders Medicine
  • Distinguished University Scholar

UofL Physicians Outpatient Center
401 East Chestnut Street, Ste. 310
Louisville, KY 40202
502-852-5241 - Academic Office
502-588-4600 - Patient Appointments


Clinical Expertise
Interstitial Lung Disease; Pulmonary Fibrosis; Sarcoidosis

 

Board Certifications

  • American Board of Internal Medicine -
    Internal Medicine / Pulmonary Disease

Education and Training

  • Medical School: University of Puerto Rico
  • Residency: San Juan Veterans Affairs Medical Center
  • Fellowship: Washington University

 

Recent Publications

    • White ES, Borok Z, Brown KK, Eickelberg O, Guenther A, Jenkins RG, Kolb M, Martinez FJ, Roman J, Sime P; American Thoracic Society Respiratory Cell and Molecular Biology Assembly Working Group on Pulmonary Fibrosis. An American Thoracic Society Official Research Statement: Future Directions in Lung Fibrosis Research. Am J Respir Crit Care Med. 2016 Apr 1;193(7):792-800. doi: 10.1164/rccm.201602-0254ST. PubMed PMID: 27035782.
    • Watson WH, Ritzenthaler JD, Roman J. Lung extracellular matrix and redox regulation. Redox Biol. 2016 Feb 18;8:305-315. doi: 10.1016/j.redox.2016.02.005. [Epub ahead of print] PubMed PMID: 26938939; PubMed Central PMCID: PMC4777985.
    • Williams K, Roman J. Studying human respiratory disease in animals - role of induced and naturally occurring models. J Pathol. 2016 Jan;238(2):220-32. doi: 10.1002/path.4658. Review. PubMed PMID: 26467890.
    • Roman J. The Puerto Rico Healthcare Crisis. Ann Am Thorac Soc. 2015 Dec;12(12):1760-3. doi: 10.1513/AnnalsATS.201508-531PS. PubMed PMID: 26551268.
    • Massey VL, Poole LG, Siow DL, Torres E, Warner NL, Schmidt RH, Ritzenthaler JD, Roman J, Arteel GE. Chronic Alcohol Exposure Enhances Lipopolysaccharide-Induced Lung Injury in Mice: Potential Role of Systemic Tumor Necrosis Factor-Alpha. Alcohol Clin Exp Res. 2015 Oct;39(10):1978-88. doi: 10.1111/acer.12855. Epub 2015 Sep 18. PubMed PMID: 26380957; PubMed Central PMCID: PMC4804458.
    • Massey VL, Beier JI, Ritzenthaler JD, Roman J, Arteel GE. Potential Role of the Gut/Liver/Lung Axis in Alcohol-Induced Tissue Pathology. Biomolecules. 2015 Sep 30;5(4):2477-503. doi: 10.3390/biom5042477. Review. PubMed PMID: 26437442; PubMed Central PMCID: PMC4693244.
    • Song N, Liu J, Shaheen S, Du L, Proctor M, Roman J, Yu J. Vagotomy attenuates bleomycin-induced pulmonary fibrosis in mice. Sci Rep. 2015 Aug 20;5:13419. doi: 10.1038/srep13419. PubMed PMID: 26289670; PubMed Central PMCID: PMC4542162.
    • Zhong X, Fan Y, Ritzenthaler JD, Zhang W, Wang K, Zhou Q, Roman J. Novel link between prostaglandin E2 (PGE2) and cholinergic signaling in lung cancer: The role of c-Jun in PGE2-induced α7 nicotinic acetylcholine receptor expression and tumor cell proliferation. Thorac Cancer. 2015 Jul;6(4):488-500. doi: 10.1111/1759-7714.12219. Epub 2015 Jan 14. PubMed PMID: 26273406; PubMed Central PMCID: PMC4511329.
    • Goodson WH 3rd, Lowe L, Carpenter DO, Gilbertson M, Manaf Ali A, Lopez de Cerain Salsamendi A, Lasfar A, Carnero A, Azqueta A, Amedei A, Charles AK, Collins AR, Ward A, Salzberg AC, Colacci A, Olsen AK, Berg A, Barclay BJ, Zhou BP, Blanco-Aparicio C, Baglole CJ, Dong C, Mondello C, Hsu CW, Naus CC, Yedjou C, Curran CS, Laird DW, Koch DC, Carlin DJ, Felsher DW, Roy D, Brown DG, Ratovitski E, Ryan EP, Corsini E, Rojas E, Moon EY, Laconi E, Marongiu F, Al-Mulla F, Chiaradonna F, Darroudi F, Martin FL, Van Schooten FJ, Goldberg GS, Wagemaker G, Nangami GN, Calaf GM, Williams G, Wolf GT, Koppen G, Brunborg G, Lyerly HK, Krishnan H, Ab Hamid H, Yasaei H, Sone H, Kondoh H, Salem HK, Hsu HY, Park HH, Koturbash I, Miousse IR, Scovassi AI, Klaunig JE, Vondráček J, Raju J, Roman J, Wise JP Sr, Whitfield JR, Woodrick J, Christopher JA, Ochieng J, Martinez-Leal JF, Weisz J, Kravchenko J, Sun J, Prudhomme KR, Narayanan KB, Cohen-Solal KA, Moorwood K, Gonzalez L, Soucek L, Jian L, D'Abronzo LS, Lin LT, Li L, Gulliver L, McCawley LJ, Memeo L, Vermeulen L, Leyns L, Zhang L, Valverde M, Khatami M, Romano MF, Chapellier M, Williams MA, Wade M, Manjili MH, Lleonart ME, Xia M, Gonzalez MJ, Karamouzis MV, Kirsch-Volders M, Vaccari M, Kuemmerle NB, Singh N, Cruickshanks N, Kleinstreuer N, van Larebeke N, Ahmed N, Ogunkua O, Krishnakumar PK, Vadgama P, Marignani PA, Ghosh PM, Ostrosky-Wegman P, Thompson PA, Dent P, Heneberg P, Darbre P, Sing Leung P, Nangia-Makker P, Cheng QS, Robey RB, Al-Temaimi R, Roy R, Andrade-Vieira R, Sinha RK, Mehta R, Vento R, Di Fiore R, Ponce-Cusi R, Dornetshuber-Fleiss R, Nahta R, Castellino RC, Palorini R, Abd Hamid R, Langie SA, Eltom SE, Brooks SA, Ryeom S, Wise SS, Bay SN, Harris SA, Papagerakis S, Romano S, Pavanello S, Eriksson S, Forte S, Casey SC, Luanpitpong S, Lee TJ, Otsuki T, Chen T, Massfelder T, Sanderson T, Guarnieri T, Hultman T, Dormoy V, Odero-Marah V, Sabbisetti V, Maguer-Satta V, Rathmell WK, Engström W, Decker WK, Bisson WH, Rojanasakul Y, Luqmani Y, Chen Z, Hu Z. Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. Carcinogenesis. 2015 Jun;36 Suppl 1:S254-96. doi: 10.1093/carcin/bgv039. Review. Erratum in: Carcinogenesis. 2016 Mar;37(3):344. PubMed PMID: 26106142; PubMed Central PMCID: PMC4480130.
    • Casey SC, Vaccari M, Al-Mulla F, Al-Temaimi R, Amedei A, Barcellos-Hoff MH, Brown DG, Chapellier M, Christopher J, Curran CS, Forte S, Hamid RA, Heneberg P, Koch DC, Krishnakumar PK, Laconi E, Maguer-Satta V, Marongiu F, Memeo L, Mondello C, Raju J, Roman J, Roy R, Ryan EP, Ryeom S, Salem HK, Scovassi AI, Singh N, Soucek L, Vermeulen L, Whitfield JR, Woodrick J, Colacci A, Bisson WH, Felsher DW. The effect of environmental chemicals on the tumor microenvironment. Carcinogenesis. 2015 Jun;36 Suppl 1:S160-83. doi: 10.1093/carcin/bgv035. Review. PubMed PMID: 26106136; PubMed Central PMCID: PMC4565612.
    • Woolery KT, Mohamed M, Linger RJ, Dobrinski KP, Roman J, Kruk PA. BRCA1 185delAG Mutation Enhances Interleukin-1β Expression in Ovarian Surface Epithelial Cells. Biomed Res Int. 2015;2015:652017. doi: 10.1155/2015/652017. Epub 2015 Aug 19. PubMed PMID: 26357657; PubMed Central PMCID: PMC4556869.
    • Jin S, Merchant ML, Ritzenthaler JD, McLeish KR, Lederer ED, Torres-Gonzalez E, Fraig M, Barati MT, Lentsch AB, Roman J, Klein JB, Rane MJ. Baclofen, a GABABR agonist, ameliorates immune-complex mediated acute lung injury by modulating pro-inflammatory mediators. PLoS One. 2015 Apr 7;10(4):e0121637. doi: 10.1371/journal.pone.0121637. eCollection 2015. PubMed PMID: 25848767; PubMed Central PMCID: PMC4388838.