Eleanor D. Lederer, M.D., FASN, FACP

Eleanor D. Lederer, M.D., FASN, FACP

Eleanor D. Lederer, M.D., FASN

Eleanor D. Lederer, M.D., FASN, FACP

  • Professor of Medicine
  • Chief, Division of Nephrology & Hypertension
  • Director, Nephrology Training Program
UofL Physicians Outpatient Center
401 East Chestnut Street, Ste. 690
Louisville, KY 40202

502-852-5757 - Academic Office
502-588-4710 - Patient Appointments


Clinical Expertise
Nephrology; Transplant; Kidney Stones; Genetic Kidney Disease; High Risk Pregnancy

 

Board Certifications

  • American Board of Internal Medicine -
    Internal Medicine / Nephrology

 

Education and Training

  • Medical School: Baylor University College of Medicine
  • Residency: Baylor University Affiliated Hospitals
  • Fellowship: Baylor University College of Medicine

 

    Recent Publications

        • Khundmiri SJ, Murray RD, Lederer E. PTH and Vitamin D. Compr Physiol. 2016 Mar 15;6(2):561-601. doi: 10.1002/cphy.c140071. PubMed PMID: 27065162.
        • Murray RD, Merchant ML, Hardin E, Clark B, Khundmiri SJ, Lederer ED. Identification of an RNA-binding protein that is phosphorylated by PTH and potentially mediates PTH-induced destabilization of Npt2a mRNA. Am J Physiol Cell Physiol. 2016 Feb 1;310(3):C205-15. doi: 10.1152/ajpcell.00192.2015. Epub 2015 Nov 25. PubMed PMID: 26834145.
        • Ketchem CJ, Khundmiri SJ, Gaweda AE, Murray R, Clark BJ, Weinman EJ, Lederer ED. Role of Na+/H+ exchanger regulatory factor 1 in forward trafficking of the type IIa Na+-Pi cotransporter. Am J Physiol Renal Physiol. 2015 Jul 15;309(2):F109-19. PubMed PMID: 25995109; PubMed Central PMCID: PMC4504931.
        • Jin S, Merchant ML, Ritzenthaler JD, McLeish KR, Lederer ED, Torres-Gonzalez E, Fraig M, Barati MT, Lentsch AB, Roman J, Klein JB, Rane MJ. Baclofen, a GABABR agonist, ameliorates immune-complex mediated acute lung injury by modulating pro-inflammatory mediators. PLoS One. 2015 Apr 7;10(4):e0121637. doi: 10.1371/journal.pone.0121637. eCollection 2015. PubMed PMID: 25848767; PubMed Central PMCID: PMC4388838.
        • Lederer E. Regulation of serum phosphate. J Physiol. 2014 Sep 15;592(18):3985-95. doi: 10.1113/jphysiol.2014.273979. Epub 2014 Jun 27. Review. PubMed PMID: 24973411; PubMed Central PMCID: PMC4198009.
        • Lederer E. Renal phosphate transporters. Curr Opin Nephrol Hypertens. 2014 Sep;23(5):502-6. doi: 10.1097/MNH.0000000000000053. Review. PubMed PMID: 25028980; PubMed Central PMCID: PMC4361807.
        • Khundmiri SJ, Salyer SA, Farmer B, Qipshidze-Kelm N, Murray RD, Clark BJ, Xie Z, Pressley TA, Lederer ED. Structural determinants for the ouabain-stimulated increase in Na-K ATPase activity. Biochim Biophys Acta. 2014 Jun;1843(6):1089-102. doi: 10.1016/j.bbamcr.2014.02.005. Epub 2014 Feb 22. PubMed PMID: 24566089.
        • Pushpakumar S, Kundu S, Pryor T, Givvimani S, Lederer E, Tyagi SC, Sen U. Angiotensin-II induced hypertension and renovascular remodelling in tissue inhibitor of metalloproteinase 2 knockout mice. J Hypertens. 2013 Nov;31(11):2270-81; discussion 2281. doi: 10.1097/HJH.0b013e3283649b33. PubMed PMID: 24077247; PubMed Central PMCID: PMC4000563.
        • Salyer SA, Parks J, Barati MT, Lederer ED, Clark BJ, Klein JD, Khundmiri SJ. Aldosterone regulates Na(+), K(+) ATPase activity in human renal proximal tubule cells through mineralocorticoid receptor. Biochim Biophys Acta. 2013 Oct;1833(10):2143-52. doi: 10.1016/j.bbamcr.2013.05.009. Epub 2013 May 16. PubMed PMID: 23684706.
        • Salyer SA, Olberding JR, Distler AA, Lederer ED, Clark BJ, Delamere NA, Khundmiri SJ. Vacuolar ATPase driven potassium transport in highly metastatic breast cancer cells. Biochim Biophys Acta. 2013 Oct;1832(10):1734-43. doi: 10.1016/j.bbadis.2013.04.023. Epub 2013 Apr 29. PubMed PMID: 23639630.