Gerald W. Dryden, M.D., Ph.D., MSPH, M.Sc.

Gerald W. Dryden, M.D., Ph.D., MSPH, M.Sc.

Gerald W. Dryden, M.D., MSPH, M.Sc.

Gerald W. Dryden, M.D., Ph.D., MSPH, M.Sc.

  • Professor of Medicine
  • Director, Inflammatory Bowel Disease Program
UofL Physicians Outpatient Center
401 East Chestnut Street, Ste. 310
Louisville, KY 40202

502-852-6991 - Academic Office
502-588-4600 - Patient Appointments

Clinical Expertise
Hepatology; Inflammatory Bowel Disease; Endoscopic Device Development


Board Certifications
  • American Board of Internal Medicine -


Education and Training

  • Medical School: University of Kentucky
  • Residency: Naval Medical Center, Portsmouth, Va.
  • Fellowship: Naval Medical Center, San Diego, Calif.
  • Ph.D.: University of Louisville
  • MSPH: University of Louisville


Featured Publications

  • Brant SR, Okou DT, Simpson CL, Cutler DJ, Haritunians T, Bradfield JP, Chopra P, Prince J, Begum F, Kumar A, Huang C, Venkateswaran S, Datta LW, Wei Z, Thomas K, Herrinton LJ, Klapproth JA, Quiros AJ, Seminerio J, Liu Z, Alexander JS, Baldassano RN, Dudley-Brown S, Cross RK, Dassopoulos T, Denson LA, Dhere TA, Dryden GW, Hanson JS, Hou JK, Hussain SZ, Hyams JS, Isaacs KL, Kader H, Kappelman MD, Katz J, Kellermayer R, Kirschner BS, Kuemmerle JF, Kwon JH, Lazarev M, Li E, Mack D, Mannon P, Moulton DE, Newberry RD, Osuntokun BO, Patel AS, Saeed SA, Targan SR, Valentine JF, Wang MH, Zonca M, Rioux JD, Duerr RH, Silverberg MS, Cho JH, Hakonarson H, Zwick ME, McGovern DP, Kugathasan S. Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease. Gastroenterology. 2017 Jan;152(1):206-217.e2. doi: 10.1053/j.gastro.2016.09.032. Epub 2016 Sep 28. PubMed PMID: 27693347; PubMed Central PMCID: PMC5164948.
  • Bhutiani N, Grizzle WE, Galandiuk S, Otali D, Dryden GW, Egilmez NK, McNally LR. Non-invasive Imaging of Colitis using Multispectral Optoacoustic Tomography. J Nucl Med. 2016 Dec 1. pii: jnumed.116.184705. [Epub ahead of print] PubMed PMID: 27908970.
  • Sandborn WJ, Colombel JF, Ghosh S, Sands BE, Dryden G, Hébuterne X, Leong RW, Bressler B, Ullman T, Lakatos PL, Reinisch W, Xu LA, Luo A. Eldelumab [Anti-IP-10] Induction Therapy for Ulcerative Colitis: A Randomised, Placebo-Controlled, Phase 2b Study. J Crohns Colitis. 2016 Apr;10(4):418-28. doi: 10.1093/ecco-jcc/jjv224. Epub 2015 Dec 30. PubMed PMID: 26721935; PubMed Central PMCID: PMC4946756.
  • Dryden GW. Optimizing the Use of Biologic Therapies in the Management of Inflammatory Bowel Disease. Gastroenterol Hepatol (N Y). 2015 Dec;11(12):853-6. PubMed PMID: 27134604; PubMed Central PMCID: PMC4849516.
  • Kosiewicz MM, Dryden GW, Chhabra A, Alard P. Relationship between gut microbiota and development of T cell associated disease. FEBS Lett. 2014 Nov 17;588(22):4195-206. doi: 10.1016/j.febslet.2014.03.019. Epub 2014 Mar 26. Review. PubMed PMID: 24681103.
  • Wang B, Zhuang X, Deng ZB, Jiang H, Mu J, Wang Q, Xiang X, Guo H, Zhang L, Dryden G, Yan J, Miller D, Zhang HG. Targeted drug delivery to intestinal macrophages by bioactive nanovesicles released from grapefruit. Mol Ther. 2014 Mar;22(3):522-34. doi: 10.1038/mt.2013.190. Epub 2013 Aug 13. PubMed PMID: 23939022; PubMed Central PMCID: PMC3944329.
  • Dryden GW, Lam A, Beatty K, Qazzaz HH, McClain CJ. A pilot study to evaluate the safety and efficacy of an oral dose of (-)-epigallocatechin-3-gallate-rich polyphenon E in patients with mild to moderate ulcerative colitis. Inflamm Bowel Dis. 2013 Aug;19(9):1904-12. doi: 10.1097/MIB.0b013e31828f5198. PubMed PMID: 23846486.
  • Li Y, Gobin AM, Dryden GW, Kang X, Xiao D, Li SP, Zhang G, Martin RC. Infrared light-absorbing gold/gold sulfide nanoparticles induce cell death in esophageal adenocarcinoma. Int J Nanomedicine. 2013;8:2153-61. doi: 10.2147/IJN.S37140. Epub 2013 Jun 18. PubMed PMID: 23818775; PubMed Central PMCID: PMC3693818.
  • Schiffman SC, Li Y, Dryden G, Li X, Martin RC. Positive correlation of image analysis by mini-endoscopy with micro-PET scan and histology in rats after esophagoduodenal anastomosis. Surg Endosc. 2010 Nov;24(11):2835-41. doi: 10.1007/s00464-010-1059-1. Epub 2010 May 4. PubMed PMID: 20440518.
  • Sands BE, Jacobson EW, Sylwestrowicz T, Younes Z, Dryden G, Fedorak R, Greenbloom S. Randomized, double-blind, placebo-controlled trial of the oral interleukin-12/23 inhibitor apilimod mesylate for treatment of active Crohn's disease. Inflamm Bowel Dis. 2010 Jul;16(7):1209-18. doi: 10.1002/ibd.21159. PubMed PMID: 19918967.