Gerald W. Dryden, M.D., Ph.D., MSPH, M.Sc.

Gerald W. Dryden, M.D., MSPH, M.Sc.

Gerald W. Dryden, M.D., Ph.D., MSPH, M.Sc.

  • Professor of Medicine
  • Director, Inflammatory Bowel Disease Program
UofL Physicians Outpatient Center
401 East Chestnut Street, Ste. 310
Louisville, KY 40202

502-852-6991 - Academic Office
502-588-4600 - Patient Appointments


Clinical Expertise
Hepatology; Inflammatory Bowel Disease; Endoscopic Device Development


Education and Training

  • Medical School: University of Kentucky
  • Residency: Naval Medical Center, Portsmouth, Va.
  • Fellowship: Naval Medical Center, San Diego, Calif.
  • Ph.D.: University of Louisville
  • MSPH: University of Louisville

Featured Publications

  • Singh R, Chandrashekharappa S, Bodduluri SR, Baby BV, Hegde B, Kotla NG, Hiwale AA, Saiyed T, Patel P, Vijay-Kumar M, Langille MGI, Douglas GM, Cheng X, Rouchka EC, Waigel SJ, Dryden GW, Alatassi H, Zhang HG, Haribabu B, Vemula PK, Jala VR. Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway. Nat Commun. 2019 Jan 9;10(1):89. doi: 10.1038/s41467-018-07859-7. PubMed PMID: 30626868; PubMed Central PMCID: PMC6327034.
  • Liaquat H, Ashat M, Stocker A, McElmurray L, Beatty K, Abell TL, Dryden G. Clinical Efficacy of Serum-Derived Bovine Immunoglobulin in Patients With Refractory Inflammatory Bowel Disease. Am J Med Sci. 2018 Dec;356(6):531-536. doi: 10.1016/j.amjms.2018.08.019. Epub 2018 Sep 5. PubMed PMID: 30342719.
  • Herfarth H, Barnes EL, Valentine JF, Hanson J, Higgins PDR, Isaacs KL, Jackson S, Osterman MT, Anton K, Ivanova A, Long MD, Martin C, Sandler RS, Abraham B, Cross RK, Dryden G, Fischer M, Harlan W, Levy C, McCabe R, Polyak S, Saha S, Williams E, Yajnik V, Serrano J, Sands BE, Lewis JD; Clinical Research Alliance of the Crohn’s and Colitis Foundation. Methotrexate Is Not Superior to Placebo in Maintaining Steroid-Free Response or Remission in Ulcerative Colitis. Gastroenterology. 2018 Oct;155(4):1098-1108.e9. doi: 10.1053/j.gastro.2018.06.046. Epub 2018 Jun 30. PubMed PMID: 29964043; PubMed Central PMCID: PMC6174092.
  • Mehta M, Ahmed S, Dryden G. Refractory pouchitis improves after administration of the green tea polyphenol EGCG: a retrospective review. Int J Colorectal Dis. 2018 Jan;33(1):83-86. doi: 10.1007/s00384-017-2906-5. Epub 2017 Sep 20. PubMed PMID: 28929216.
  • Auci DL, Egilmez NK, Dryden GW. Anti-Fibrotic Potential of All Trans Retinoic Acid in Inflammatory Bowel Disease. J Gastroenterol Pancreatol Liver Disord. 2018;6(3). doi: 10.15226/2374-815X/6/3/001126. Epub 2018 May 28. PubMed PMID: 30740522; PubMed Central PMCID: PMC6366833.
  • Netz U, Carter J, Eichenberger MR, Feagins K, Galbraith NJ, Dryden GW, Pan J, Rai SN, Galandiuk S. Plasma microRNA Profile Differentiates Crohn's Colitis From Ulcerative Colitis. Inflamm Bowel Dis. 2017 Dec 19;24(1):159-165. doi: 10.1093/ibd/izx009. PubMed PMID: 29272478; PubMed Central PMCID: PMC5858028.
  • Dryden GW, Boland E, Yajnik V, Williams S. Comparison of Stromal Vascular Fraction with or Without a Novel Bioscaffold to Fibrin Glue in a Porcine Model of Mechanically Induced Anorectal Fistula. Inflamm Bowel Dis. 2017 Nov;23(11):1962-1971. doi: 10.1097/MIB.0000000000001254. PubMed PMID: 28945635.
  • Mehta M, Ahmed S, Dryden G. Immunopathophysiology of inflammatory bowel disease: how genetics link barrier dysfunction and innate immunity to inflammation. Innate Immun. 2017 Aug;23(6):497-505. doi: 10.1177/1753425917722206. Review. PubMed PMID: 28770665.
  • Netz U, Carter JV, Eichenberger MR, Dryden GW, Pan J, Rai SN, Galandiuk S. Genetic polymorphisms predict response to anti-tumor necrosis factor treatment in Crohn's disease. World J Gastroenterol. 2017 Jul 21;23(27):4958-4967. doi: 10.3748/wjg.v23.i27.4958. PubMed PMID: 28785150; PubMed Central PMCID: PMC5526766.
  • Bhutiani N, Grizzle WE, Galandiuk S, Otali D, Dryden GW, Egilmez NK, McNally LR. Noninvasive Imaging of Colitis Using Multispectral Optoacoustic Tomography. J Nucl Med. 2017 Jun;58(6):1009-1012. doi: 10.2967/jnumed.116.184705. Epub 2016 Dec 1. PubMed PMID: 27908970; PubMed Central PMCID: PMC5450363.