Gerald W. Dryden, M.D., Ph.D., MSPH, M.Sc.

Gerald W. Dryden, M.D., Ph.D., MSPH, M.Sc.

Gerald W. Dryden, M.D., MSPH, M.Sc.

Gerald W. Dryden, M.D., Ph.D., MSPH, M.Sc.

  • Professor of Medicine
  • Director, Inflammatory Bowel Disease Program
UofL Physicians Outpatient Center
401 East Chestnut Street, Ste. 310
Louisville, KY 40202

502-852-6991 - Academic Office
502-588-4600 - Patient Appointments

Clinical Expertise
Hepatology; Inflammatory Bowel Disease; Endoscopic Device Development


Board Certifications
  • American Board of Internal Medicine -


Education and Training

  • Medical School: University of Kentucky
  • Residency: Naval Medical Center, Portsmouth, Va.
  • Fellowship: Naval Medical Center, San Diego, Calif.
  • Ph.D.: University of Louisville
  • MSPH: University of Louisville


Recent Publications

        • Sandborn WJ, Colombel JF, Ghosh S, Sands BE, Dryden G, Hébuterne X, Leong RW,  Bressler B, Ullman T, Lakatos PL, Reinisch W, Xu LA, Luo A. Eldelumab [Anti-IP-10] Induction Therapy for Ulcerative Colitis: A Randomised, Placebo-Controlled, Phase 2b Study. J Crohns Colitis. 2016 Apr;10(4):418-28. doi: 10.1093/ecco-jcc/jjv224. Epub 2015 Dec 30. PubMed PMID: 26721935.
        • Kosiewicz MM, Dryden GW, Chhabra A, Alard P. Relationship between gut microbiota and development of T cell associated disease. FEBS Lett. 2014 Nov 17;588(22):4195-206. doi: 10.1016/j.febslet.2014.03.019. Epub 2014 Mar 26. Review. PubMed PMID: 24681103.
        • Wang B, Zhuang X, Deng ZB, Jiang H, Mu J, Wang Q, Xiang X, Guo H, Zhang L, Dryden G, Yan J, Miller D, Zhang HG. Targeted drug delivery to intestinal macrophages by bioactive nanovesicles released from grapefruit. Mol Ther. 2014 Mar;22(3):522-34. doi: 10.1038/mt.2013.190. Epub 2013 Aug 13. PubMed PMID: 23939022; PubMed Central PMCID: PMC3944329.
        • Dryden GW, Lam A, Beatty K, Qazzaz HH, McClain CJ. A pilot study to evaluate the safety and efficacy of an oral dose of (-)-epigallocatechin-3-gallate-rich polyphenon E in patients with mild to moderate ulcerative colitis. Inflamm Bowel Dis. 2013 Aug;19(9):1904-12. doi: 10.1097/MIB.0b013e31828f5198. PubMed PMID: 23846486.
        • Li Y, Gobin AM, Dryden GW, Kang X, Xiao D, Li SP, Zhang G, Martin RC. Infrared light-absorbing gold/gold sulfide nanoparticles induce cell death in esophageal adenocarcinoma. Int J Nanomedicine. 2013;8:2153-61. doi: 10.2147/IJN.S37140. Epub 2013 Jun 18. PubMed PMID: 23818775; PubMed Central PMCID: PMC3693818.
        • Schiffman SC, Li Y, Dryden G, Li X, Martin RC. Positive correlation of image analysis by mini-endoscopy with micro-PET scan and histology in rats after esophagoduodenal anastomosis. Surg Endosc. 2010 Nov;24(11):2835-41. doi: 10.1007/s00464-010-1059-1. Epub 2010 May 4. PubMed PMID: 20440518.
        • Sands BE, Jacobson EW, Sylwestrowicz T, Younes Z, Dryden G, Fedorak R, Greenbloom S. Randomized, double-blind, placebo-controlled trial of the oral interleukin-12/23 inhibitor apilimod mesylate for treatment of active Crohn's disease. Inflamm Bowel Dis. 2010 Jul;16(7):1209-18. doi: 10.1002/ibd.21159. PubMed PMID: 19918967.
        • Dryden GW Jr. Overview of biologic therapy for Crohn's disease. Expert Opin Biol Ther. 2009 Aug;9(8):967-74. doi: 10.1517/14712590903048909. Review. PubMed PMID: 19591627.
        • Dryden GW. Overview of stem cell therapy for Crohn's disease. Expert Opin Biol Ther. 2009 Jul;9(7):841-7. doi: 10.1517/14712590902956615. Review. PubMed PMID: 19527107.
        • Harrell SP, Studts JL, Dryden GW, Eversmann J, Cai L, Wo JM. A novel classification scheme for gastroparesis based on predominant-symptom presentation. J Clin Gastroenterol. 2008 May-Jun;42(5):455-9. doi: 10.1097/MCG.0b013e31815ed084. PubMed PMID: 18344894.