Gerald W. Dryden, M.D., Ph.D., MSPH, M.Sc.

Gerald W. Dryden, M.D., Ph.D., MSPH, M.Sc.

Gerald W. Dryden, M.D., MSPH, M.Sc.

Gerald W. Dryden, M.D., Ph.D., MSPH, M.Sc.

  • Professor of Medicine
  • Director, Inflammatory Bowel Disease Program
UofL Physicians Outpatient Center
401 East Chestnut Street, Ste. 310
Louisville, KY 40202

502-852-6991 - Academic Office
502-588-4600 - Patient Appointments

Clinical Expertise
Hepatology; Inflammatory Bowel Disease; Endoscopic Device Development


Board Certifications
  • American Board of Internal Medicine -


Education and Training

  • Medical School: University of Kentucky
  • Residency: Naval Medical Center, Portsmouth, Va.
  • Fellowship: Naval Medical Center, San Diego, Calif.
  • Ph.D.: University of Louisville
  • MSPH: University of Louisville


Featured Publications

  • Mehta M, Ahmed S, Dryden G. Refractory pouchitis improves after administration of the green tea polyphenol EGCG: a retrospective review. Int J Colorectal Dis. 2018 Jan;33(1):83-86. doi: 10.1007/s00384-017-2906-5. Epub 2017 Sep 20. PubMed PMID: 28929216.
  • Netz U, Carter J, Eichenberger MR, Feagins K, Galbraith NJ, Dryden GW, Pan J, Rai SN, Galandiuk S. Plasma microRNA Profile Differentiates Crohn's Colitis From Ulcerative Colitis. Inflamm Bowel Dis. 2017 Dec 19;24(1):159-165. doi: 10.1093/ibd/izx009. PubMed PMID: 29272478; PubMed Central PMCID: PMC5858028.
  • Dryden GW, Boland E, Yajnik V, Williams S. Comparison of Stromal Vascular Fraction with or Without a Novel Bioscaffold to Fibrin Glue in a Porcine Model of Mechanically Induced Anorectal Fistula. Inflamm Bowel Dis. 2017 Nov;23(11):1962-1971. doi: 10.1097/MIB.0000000000001254. PubMed PMID: 28945635.
  • Mehta M, Ahmed S, Dryden G. Immunopathophysiology of inflammatory bowel disease: how genetics link barrier dysfunction and innate immunity to inflammation. Innate Immun. 2017 Aug;23(6):497-505. doi: 10.1177/1753425917722206. PubMed PMID: 28770665.
  • Netz U, Carter JV, Eichenberger MR, Dryden GW, Pan J, Rai SN, Galandiuk S. Genetic polymorphisms predict response to anti-tumor necrosis factor treatment in Crohn's disease. World J Gastroenterol. 2017 Jul 21;23(27):4958-4967. doi: 10.3748/wjg.v23.i27.4958. PubMed PMID: 28785150; PubMed Central PMCID: PMC5526766.
  • Bhutiani N, Grizzle WE, Galandiuk S, Otali D, Dryden GW, Egilmez NK, McNally LR. Noninvasive Imaging of Colitis Using Multispectral Optoacoustic Tomography. J Nucl Med. 2017 Jun;58(6):1009-1012. doi: 10.2967/jnumed.116.184705. Epub 2016 Dec 1. PubMed PMID: 27908970; PubMed Central PMCID: PMC5450363.
  • Liu L, Zhao C, Yang Y, Kong X, Shao T, Ren L, Zhuang X, Yin B, Dryden G, McClain C, Luan W, Feng W. Fibroblast Growth Factor 21 Deficiency Attenuates Experimental Colitis-Induced Adipose Tissue Lipolysis. Gastroenterol Res Pract. 2017;2017:3089378. doi: 10.1155/2017/3089378. Epub 2017 May 11. PubMed PMID: 28584524; PubMed Central PMCID: PMC5444037.
  • Brant SR, Okou DT, Simpson CL, Cutler DJ, Haritunians T, Bradfield JP, Chopra P, Prince J, Begum F, Kumar A, Huang C, Venkateswaran S, Datta LW, Wei Z, Thomas K, Herrinton LJ, Klapproth JA, Quiros AJ, Seminerio J, Liu Z, Alexander JS, Baldassano RN, Dudley-Brown S, Cross RK, Dassopoulos T, Denson LA, Dhere TA, Dryden GW, Hanson JS, Hou JK, Hussain SZ, Hyams JS, Isaacs KL, Kader H, Kappelman MD, Katz J, Kellermayer R, Kirschner BS, Kuemmerle JF, Kwon JH, Lazarev M, Li E, Mack D, Mannon P, Moulton DE, Newberry RD, Osuntokun BO, Patel AS, Saeed SA, Targan SR, Valentine JF, Wang MH, Zonca M, Rioux JD, Duerr RH, Silverberg MS, Cho JH, Hakonarson H, Zwick ME, McGovern DP, Kugathasan S. Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease. Gastroenterology. 2017 Jan;152(1):206-217.e2. doi: 10.1053/j.gastro.2016.09.032. Epub 2016 Sep 28. PubMed PMID: 27693347; PubMed Central PMCID: PMC5164948.
  • Sandborn WJ, Colombel JF, Ghosh S, Sands BE, Dryden G, Hébuterne X, Leong RW, Bressler B, Ullman T, Lakatos PL, Reinisch W, Xu LA, Luo A. Eldelumab [Anti-IP-10] Induction Therapy for Ulcerative Colitis: A Randomised, Placebo-Controlled, Phase 2b Study. J Crohns Colitis. 2016 Apr;10(4):418-28. doi: 10.1093/ecco-jcc/jjv224. Epub 2015 Dec 30. PubMed PMID: 26721935; PubMed Central PMCID: PMC4946756.
  • Dryden GW. Optimizing the Use of Biologic Therapies in the Management of Inflammatory Bowel Disease. Gastroenterol Hepatol (N Y). 2015 Dec;11(12):853-6. PubMed PMID: 27134604; PubMed Central PMCID: PMC4849516.