Andrew P. DeFilippis, M.D., M.Sc.

Andrew P. DeFilippis, M.D., M.Sc.

Andrew P. DeFilippis, M.D., M.Sc.

Andrew P. DeFilippis, M.D., M.Sc.

  • Assistant Professor of Medicine
  • Director, Cardiovascular Disease Prevention
UofL Physicians Outpatient Center
401 East Chestnut Street, Ste. 310
Louisville, KY 40202

502-852-7959 - Academic Office
502-588-4600 - Patient Appointments


Clinical Expertise
Coronary Artery Disease; Coronary Atherothrombosis; Lipidology; Cardiac Intensive Care

Research Interests
Biomarker development for acute myocardial infarction (atherothrombotic and non-atherothrmbotic); Cardiovascular risk prediction; Plaque disruption and coronary thrombosis; Omics

 

Board Certifications

  • American Board of Internal Medicine -
    Cardiovascular Disease

Education and Training

  • Medical School: Georgetown University
  • Residency: Emory University Hospital
  • Fellowship: Johns Hopkins University
  • M.Sc.: Emory University

 

Recent Publications

  • DeFilippis AP, Young R, McEvoy JW, Michos ED, Sandfort V, Kronmal RA, McClelland RL, Blaha MJ. Risk score overestimation: the impact of individual cardiovascular risk factors and preventive therapies on the performance of the American Heart Association-American College of Cardiology-Atherosclerotic Cardiovascular Disease risk score in a modern multi-ethnic cohort. Eur Heart J. 2016 Jul 19. pii: ehw301. [Epub ahead of print] PubMed PMID: 27436865.
  • Keith RJ, Al Rifai M, Carruba C, De Jarnett N, McEvoy JW, Bhatnagar A, Blaha MJ, Defilippis AP. Tobacco Use, Insulin Resistance, and Risk of Type 2 Diabetes: Results from the Multi-Ethnic Study of Atherosclerosis. PLoS One. 2016 Jun 20;11(6):e0157592. doi: 10.1371/journal.pone.0157592. eCollection 2016. PubMed PMID: 27322410; PubMed Central PMCID: PMC4913922.
  • Feldman DI, Cainzos-Achirica M, Billups KL, DeFilippis AP, Chitaley K, Greenland P, Stein JH, Budoff MJ, Dardari Z, Miner M, Blumenthal RS, Nasir K, Blaha MJ. Subclinical Vascular Disease and Subsequent Erectile Dysfunction: The Multiethnic Study of Atherosclerosis (MESA). Clin Cardiol. 2016 May;39(5):291-8. doi: 10.1002/clc.22530. Epub 2016 May 3. PubMed PMID: 27145089; PubMed Central PMCID: PMC4879072.
  • Loughran J, Puthawala T, Sutton BS, Brown LE, Pronovost PJ, DeFilippis AP. The Cardiovascular Intensive Care Unit-An Evolving Model for Health Care Delivery. J Intensive Care Med. 2016 Jan 13. pii: 0885066615624664. [Epub ahead of print] PubMed PMID: 26768424.
  • DeFilippis AP, Blaha MJ. Predicted vs Observed Clinical Event Risk for Cardiovascular Disease. JAMA. 2015 Nov 17;314(19):2082. doi: 10.1001/jama.2015.12916. PubMed PMID: 26575067.
  • DeFilippis AP, Chernyavskiy I, Amraotkar AR, Trainor PJ, Kothari S, Ismail I, Hargis CW, Korley FK, Leibundgut G, Tsimikas S, Rai SN, Bhatnagar A. Circulating levels of plasminogen and oxidized phospholipids bound to plasminogen distinguish between atherothrombotic and non-atherothrombotic myocardial infarction. J Thromb Thrombolysis. 2016 Jul;42(1):61-76. doi: 10.1007/s11239-015-1292-5. PubMed PMID: 26510751.
  • DeFilippis AP, Blaha MJ. Can the AHA-ACC ASCVD risk score be applied outside the United States in Korea? Atherosclerosis. 2015 Oct;242(2):560-2. doi: 10.1016/j.atherosclerosis.2015.08.019. Epub 2015 Aug 14. PubMed PMID: 26318105.
  • DeJarnett N, Yeager R, Conklin DJ, Lee J, O'Toole TE, McCracken J, Abplanalp W, Srivastava S, Riggs DW, Hamzeh I, Wagner S, Chugh A, DeFilippis A, Ciszewski T, Wyatt B, Becher C, Higdon D, Ramos KS, Tollerud DJ, Myers JA, Rai SN, Shah J, Zafar N, Krishnasamy SS, Prabhu SD, Bhatnagar A. Residential Proximity to Major Roadways Is Associated With Increased Levels of AC133+ Circulating Angiogenic Cells. Arterioscler Thromb Vasc Biol. 2015 Nov;35(11):2468-77. doi: 10.1161/ATVBAHA.115.305724. Epub 2015 Aug 20. PubMed PMID: 26293462; PubMed Central PMCID: PMC4862408.
  • DeFilippis AP, Young R, Blaha MJ. Calibration and Discrimination Among Multiple Cardiovascular Risk Scores in a Modern Multiethnic Cohort. Ann Intern Med. 2015 Jul 7;163(1):68-9. doi: 10.7326/L15-5105-2. PubMed PMID: 26148287.
  • Amraotkar AR, Hargis CW, Cambon AC, Rai SN, Keith MC, Ghafghazi S, Bolli R, DeFilippis AP. Comparison of coliform contamination in non-municipal waters consumed by the Mennonite versus the non-Mennonite rural populations. Environ Health Prev Med. 2015 Sep;20(5):338-46. doi: 10.1007/s12199-015-0472-4. Epub 2015 Jun 12. PubMed PMID: 26068785; PubMed Central PMCID: PMC4550604.
  • Amraotkar AR, Pachika A, Grubb KJ, DeFilippis AP. Rapid Extracorporeal Membrane Oxygenation Overcomes Fulminant Myocarditis Induced by 5-Fluorouracil. Tex Heart Inst J. 2016 Apr 1;43(2):178-82. doi: 10.14503/THIJ-15-5100. eCollection 2016 Apr. PubMed PMID: 27127440; PubMed Central PMCID: PMC4845572.
  • DeFilippis AP, Young R, Carrubba CJ, McEvoy JW, Budoff MJ, Blumenthal RS, Kronmal RA, McClelland RL, Nasir K, Blaha MJ. An analysis of calibration and discrimination among multiple cardiovascular risk scores in a modern multiethnic cohort. Ann Intern Med. 2015 Feb 17;162(4):266-75. doi: 10.7326/M14-1281. PubMed PMID: 25686167; PubMed Central PMCID: PMC4414494.
  • McEvoy JW, Nasir K, DeFilippis AP, Lima JA, Bluemke DA, Hundley WG, Barr RG, Budoff MJ, Szklo M, Navas-Acien A, Polak JF, Blumenthal RS, Post WS, Blaha MJ. Relationship of cigarette smoking with inflammation and subclinical vascular disease: the Multi-Ethnic Study of Atherosclerosis. Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):1002-10. doi: 10.1161/ATVBAHA.114.304960. Epub 2015 Mar 5. PubMed PMID: 25745060; PubMed Central PMCID: PMC4484586.
  • McEvoy JW, Blaha MJ, DeFilippis AP, Lima JA, Bluemke DA, Hundley WG, Min JK, Shaw LJ, Lloyd-Jones DM, Barr RG, Budoff MJ, Blumenthal RS, Nasir K. Cigarette smoking and cardiovascular events: role of inflammation and subclinical atherosclerosis from the MultiEthnic Study of Atherosclerosis. Arterioscler Thromb Vasc Biol. 2015 Mar;35(3):700-9. doi: 10.1161/ATVBAHA.114.304562. Epub 2015 Jan 8. PubMed PMID: 25573855; PubMed Central PMCID: PMC4404404.
  • Carrubba CJ, Blaha MJ, Khurram N, DeFilippis AP. Cardiovascular Disease Risk Assessment: a Review of Risk Factor-based Algorithms and Assessments of Vascular Health. Curr Cardiovasc Risk Rep (2014) 8:419