Andrew P. DeFilippis, M.D., M.Sc.

Andrew P. DeFilippis, M.D., M.Sc.

Andrew P. DeFilippis, M.D., M.Sc.

Andrew P. DeFilippis, M.D., M.Sc.

  • Assistant Professor of Medicine
  • Co-Director, Cardiovascular Disease Prevention
  • Medical Director, Cardiovascular Intensive Care Unit
University of Louisville Health Care Outpatient Center
401 East Chestnut Street, Ste. 310
Louisville, KY 40202

502-852-7959 - Academic Office
502-588-4600 - Patient Appointments

Clinical Expertise
Coronary Artery Disease; Coronary Atherothrombosis; Lipidology; Cardiac Intensive Care


Board Certifications

  • American Board of Internal Medicine -
    Internal Medicine / Cardiovascular Disease

Education and Training

  • Medical School: Georgetown University
  • Residency: Emory University Hospital
  • Fellowship: Johns Hopkins University
  • M.Sc.: Emory University


Recent Publications

    • Defilippis AP, Rai SN, Cambon A, Miles RJ, Jaffe AS, Moser AB, Jones RO, Bolli R, Schulman SP. Fatty acids and TxA2 generation, in the absence of platelet-COX-1 activity. Nutr Metab Cardiovasc Dis. 2014 Apr;24(4):428-33. doi: 10.1016/j.numecd.2013.08.012. Epub 2013 Oct 23. PubMed PMID: 24370448.
    • Makadia SS, Blaha M, Keenan T, Ndumele C, Jones S, DeFilippis A, Martin S, Kohli P, Conceicao R, Carvalho J, Nasir K, Blumenthal R, Santos RD. Relation of hepatic steatosis to atherogenic dyslipidemia. Am J Cardiol. 2013 Nov 15;112(10):1599-604. doi: 10.1016/j.amjcard.2013.08.001. Epub 2013 Sep 5. PubMed PMID: 24012029.
    • DeFilippis AP, Oloyede OS, Andrikopoulou E; Saenger AK, Palachuvattil JM, Fasoro, YA, Guallar E, Blumenthal RS, Kickler TK, Jaffe AS, Gerstenblith G, Schulman SP, Rade JJ.  Platelet COX-1-Independent TxA2 Generation in Patients with Acute Coronary Syndromes.  Circulation Journal. Aug 27, 2013.
    • Martin SS, Blaha MJ, Elshazly MB, Brinton EA, Toth PP, McEvoy JW, Joshi PH, Kulkarni KR, Mize PD, Kwiterovich PO, Defilippis AP, Blumenthal RS, Jones SR. Friedewald-estimated versus directly measured low-density lipoprotein cholesterol and treatment implications. J Am Coll Cardiol. 2013 Aug 20;62(8):732-9. doi: 10.1016/j.jacc.2013.01.079. Epub 2013 Mar 21. PubMed PMID: 23524048.
    • DeFilippis AP, Blaha MJ, Martin SS, Reed RM, Jones SR, Nasir K, Blumenthal RS, Budoff MJ. Nonalcoholic fatty liver disease and serum lipoproteins: the Multi-Ethnic Study of Atherosclerosis. Atherosclerosis. 2013 Apr;227(2):429-36. doi: 10.1016/j.atherosclerosis.2013.01.022. Epub 2013 Jan 29. PubMed PMID: 23419204.
    • DeFilippis AP, Blaha MJ, Ndumele CE, Budoff MJ, Lloyd-Jones DM, McClelland RL, Lakoski SG, Cushman M, Wong ND, Blumenthal RS, Lima J, Nasir K. The association of Framingham and Reynolds risk scores with incidence and progression of coronary artery calcification in MESA (Multi-Ethnic Study of Atherosclerosis). J Am Coll Cardiol. 2011 Nov 8;58(20):2076-83. doi: 10.1016/j.jacc.2011.08.022. PubMed PMID: 22051329.
    • Bardia A, Arieas ET, Zhang Z, Defilippis A, Tarpinian K, Jeter S, Nguyen A, Henry NL, Flockhart DA, Hayes DF, Hayden J, Storniolo AM, Armstrong DK, Davidson NE, Fetting J, Ouyang P, Wolff AC, Blumenthal RS, Ashen MD, Stearns V. Comparison of breast cancer recurrence risk and cardiovascular disease incidence risk among postmenopausal women with breast cancer. Breast Cancer Res Treat. 2012 Feb;131(3):907-14. doi: 10.1007/s10549-011-1843-1. Epub 2011 Nov 1. PubMed PMID: 22042368; PubMed Central PMCID: PMC3582017.
    • Reed RM, Hashmi S, Eberlein M, Iacono A, Netzer G, DeFilippis A, Girgis RE, Toth PP, Scharf S, Jones S. Impact of lung transplantation on serum lipids in COPD. Respir Med. 2011 Dec;105(12):1961-8. doi: 10.1016/j.rmed.2011.10.003. Epub 2011 Oct 21. PubMed PMID: 22019328.
    • Blaha MJ, Budoff MJ, DeFilippis AP, Blankstein R, Rivera JJ, Agatston A, O'Leary DH, Lima J, Blumenthal RS, Nasir K. Associations between C-reactive protein, coronary artery calcium, and cardiovascular events: implications for the JUPITER population from MESA, a population-based cohort study. Lancet. 2011 Aug 20;378(9792):684-92. doi: 10.1016/S0140-6736(11)60784-8. PubMed PMID: 21856482; PubMed Central PMCID: PMC3173039.
    • Blaha MJ, DeFilippis AP, Rivera JJ, Budoff MJ, Blankstein R, Agatston A, Szklo M, Lakoski SG, Bertoni AG, Kronmal RA, Blumenthal RS, Nasir K. The relationship between insulin resistance and incidence and progression of coronary artery calcification: the Multi-Ethnic Study of Atherosclerosis (MESA). Diabetes Care. 2011 Mar;34(3):749-51. doi: 10.2337/dc10-1681. Epub 2011 Feb 3. PubMed PMID: 21292863; PubMed Central PMCID: PMC3041221.