Research

Research

The University of Louisville is a nationally-recognized academic institution, and our faculty members are eager to take on interested students and residents.

Dr. Panchabhai with posterOne of our major program goals is to provide opportunities for our trainees to engage in both clinical and bench research.

Each house officer is required to complete a “scholarly project” during his or her residency. This may be a research effort with written results, a presentation at a conference, a publication in a national journal, or a curricular proposal.

Residents also participate in a joint academic retreat (“Shakertown”) with their counterparts from the University of Kentucky residency program.

The following is a resume of our trainees' recent scholarly efforts:

 

PUBLICATIONS


Peer-Reviewed Articles

 

  • Bhatia N, Abushora MY, Donneyong MM, Stoddard MF. Determination of the Optimum Number of Cardiac Cycles to Differentiate Intrapulmonary Shunt and Patent Foramen Ovale by Saline Contrast Two- and Three-Dimensional Echocardiography. Echocardiography. June 2013.
  • Bhatia N, Abushora MY, Alnabki Z, Shenoy M, Alshaher M, Stoddard MF. Intrapulmonary shunt is a potentially unrecognized cause of ischemic stroke and transient ischemic attack. J Am Soc Echocardiogr. 2013 Jul;26(7):683-90.
  • Daher IN, Daigle TR, Bhatia N, Durand JB. The prevention of cardiovascular disease in cancer survivors. Tex Heart Inst J. 2012;39(2):190-8.
  • Leucker TM, Singh S, and Moffett BK. Fluoxetine Inhibition of CYP3A4 Potentiating Adrenal Suppression and Peptic Ulcer Disease from Intra-Articular Triamcinolone Injections. Pain Med. 2013 Apr 8.
  • Leucker TM, Williams ML, Flaherty MP. Transcatheter aortic valve replacement: A novel abdominal transaortic approach. Catheter Cardiovasc Interv. 2013.
  • Leucker TM, Ge ZD, Procknow J, Liu Y, Shi Y, Bienengraeber M, Warltier DC, Kersten JR. Impairment of Endothelial-myocardial Interaction Increases the Susceptibility of Cardiomyocytes to Ischemia/reperfusion Injury. PLoS One.2013.
  • Leucker TM, Reddy SV, Moffett BK. Methicillin-resistant Staphylococcus Aureus Induced Reactive Arthritis Treated With Systemic Corticosteroid. Am J Med Sci. 2013 Mar 13.
  • Vladic N, Ge ZD, Leucker T, Brzezinska AK, Du JH, Shi Y, Warltier DC, Pratt PF Jr., Kersten JR. Decreased tetrahydrobiopterin and disrupted association of Hsp90 with eNOS by hyperglycemia impair myocardial ischemic preconditioning. Am J Physiol Heart Circ Physiol.2011 Nov;301(5):H2130-9.
  • Leucker TM, Bienengraeber M, Muravyeva M, Baotic I, Weihrauch D, Brzezinska AK, Warltier DC, Kersten JR, Pratt PF Jr. Endothelial-cardiomyocyte crosstalk enhances pharmacological cardioprotection. J Mol Cell Cardiol.2011 Nov;51(5):803-11.
  • Bhatt G, Li XF, Jain A, Sharma VK, Pan J, Rai A, Rai SN, Civelek AC. The normal variant 18F-FDG uptake in the lower thoracic spinal cord segments in cancer patients without CNS malignancy. American Journal of Nuclear Medicine and Molecular Imaging (AJNMMI)- Am J Nucl Med Mol Imaging 2013;3(4):317-325.
  • Bhatt G, Bhatt AD, Silverman CL, Dragun AE. Pituitary apoplexy after hypo-fractionated stereotactic radiotherapy, Journal of Solid Tumors, Vol. 3, No. 3, 2013.
  • Joshi J, Kushner GM, Bhatt G, Bhatt AD, Civelek AC. Role of nuclear medicine imaging in recognizing different causes of osteonecrosis of the jaw. Interesting Images, Clinical Nuclear Medicine, 2012, Aug.

 

Peer-Reviewed Case Reports

 

  • El-Kersh K, Rawasia WF. Late sequelae of pulmonary tuberculosis. BMJ Case Rep. 2013 Apr 19;2013.
  • Rawasia WF, Chaddha U, El-Kersh K, Perez RL. Dyspnoea and the ovaries: a rare presentation of Krukenberg tumour. BMJ Case Rep. 2013 Feb 1;2013.
  • El-Kersh K, Rawasia WF, Chaddha U, Guardiola J. Rarity revisited: Cryptococcal peritonitis. BMJ Case Rep. 2013 Jul 10;2013.
  • Bhatia N, Vongooru H, Ikram S. Acute myocardial infarction and massive pulmonary embolus presenting as cardiac arrest: Initial rhythm as a diagnostic clue. Case Reports in Emergency Medicine. Case Rep Emerg Med. 2013;2013:343918.

 

Peer-Reviewed Abstracts

 

  • Bhatia N, Stoddard MF. Predictors and impact of non-circular left ventricular outflow tract shapes on estimation of severity of aortic stenosis by continuity equation. J Am Coll Cardiol. 2013;61(10_S):E876. Page 2/10.
  • Bhatia N, Abushora MY, Alnabki Z, Stoddard MF. Intrapulmonary shunt is a potentially unrecognized cause of ischemic stroke and transient ischemic attack. J Am Coll Cardiol. 2013;61(10_S):E2099.
  • Tavakoli V, Bhatia N, Stoddard MF, Amini AA. Fusion of Tissue Doppler and Speckle Tracking in Echocardiography Images: Comparison with Speckle Tracking Echocardiography. J Am Coll Cardiol. 2013;61(10_S):E1094.
  • Bhatia N, Abushora MY, Stoddard MF. Saline Contrast Three-Dimensional Echocardiography for the Detection of Intrapulmonary Shunt and Patent Foramen Ovale. J Am Soc Echocardiogr. 2013 Jun;26(6):B43.
  • Bhatia N, Abushora MY, Stoddard MF. Intrapulmonary Shunt: The Missing Link in the Etiology of Cryptogenic Ischemic Stroke and Transient Ischemic Attack ? J Am Soc Echocardiogr. 2013 Jun;26(6):B45.

 

Book Chapters

 

  • Bhatia N, Chatterjee A, Peterson H. Carotid Sinus Hypersensitivity. In: Domino F, et al. the 5-Minute Clinical Consult 2014, 22nd edition (published) and 2015, 23rd edition (In press). Philadelphia: Lippincott Williams & Wilkins, 2014 and www.5minuteconsult.com.
  • Bhatia N, Alnabki Z, Stoddard MF. Orthostatic Hypotension. In: Domino F, et al. the 5-Minute Clinical Consult 2014, 22nd edition (published) and 2015, 23rd edition (In press). Philadelphia: Lippincott Williams & Wilkins, 2014 and www.5minuteconsult.com.
  • Chatterjee A, Bhatia N, Hamzeh I. Idiopathic Hypertrophic Subaortic Stenosis (IHSS). In: Domino F, et al. the 5-Minute Clinical Consult 2014, 22nd edition (published) and 2015, 23rd edition (In press). Philadelphia: Lippincott Williams & Wilkins, 2014 and www.5minuteconsult.com.
  • Alnabki Z, Bhatia N, Stoddard MF. Mitral Valve Stenosis. In: Domino F, et al. the 5-Minute Clinical Consult 2014, 22nd edition (published) and 2015, 23rd edition (In press) Philadelphia: Lippincott Williams & Wilkins, 2014 and www.5minuteconsult.com.
  • Bhatia N, Ghotra AS, Stoddard MF. Aortic valvular stenosis. In: Domino F, et al. the 5-Minute Clinical Consult 2015, 23rd edition. Philadelphia: Lippincott Williams & Wilkins, 2015 and www.5minuteconsult.com (In press).
  • Bhatia N, Ghotra AS, Stoddard MF. Heart Murmur. In: Domino F, et al. the 5-Minute Clinical Consult 2015, 23rd edition. Philadelphia: Lippincott Williams & Wilkins, 2015 and www.5minuteconsult.com (In press).
  • Bhatia N, Lenneman CG. Congestive heart failure: differential diagnosis. In: Domino F, et al. the 5-Minute Clinical Consult 2015, 23rd edition. Philadelphia: Lippincott Williams & Wilkins, 2015 and www.5minuteconsult.com (In press).
  • Ghotra AS, Bhatia N, McCants KC. Cardiomegaly. In: Domino F, et al. the 5-Minute Clinical Consult 2015, 23rd edition. Philadelphia: Lippincott Williams & Wilkins, 2015 and www.5minuteconsult.com (In press).
  • Ghotra AS, Bhatia N, McCants KC. Syncope. In: Domino F, et al. the 5-Minute Clinical Consult 2015, 23rd edition. Philadelphia: Lippincott Williams & Wilkins, 2015 and www.5minuteconsult.com (In press).

 

Unfunded IRB-approved Research Projects

 

  • Haney M, Rawasia W, and Gopinathannair R. Outcomes with implantable cardioverter-defibrillator (ICD) generator replacement in veterans without appropriate ICD therapy and/or improved left ventricular ejection fraction during the lifetime of the index device.
  • Marsano L and Singh S. Rates of Acute Hepatitis B and C Infection Since Passage of Anti-Narcotic Legislation, KASPER
  • Wagner L and Singh S. Validity of the HgbA1c in Diabetics with Iron Deficiency Anemia

 

Presentations

 

International Conferences

 

  • Chatterjee A, Bhatia N, Gopinathannair R, Alnabki Z, Deam AG. Performance of DF4 ICD lead compared to conventional three core leads. 18th World Congress on Heart Disease (International Meeting – July 2013, Vancouver, Canada) Accepted for oral presentation.

 

National Conferences

 

  • Bhatia N, Vongooru H, Birks E, Slaughter MS, McCants KC. Clinical features and outcomes of patients with Bi-ventricular pacemaker-defibrillator versus automatic implantable defibrillator undergoing left ventricular assist device implantation. Heart Failure Society of America (National Meeting – September 2013, Orlando, FL) Poster.
  • Bhatia N, Alnabki Z, Sayfo S, Vongooru H, Birks E, McCants KC, Hamzeh I. Concomitant use of Sildenafil and Nitrates for the treatment of pulmonary arterial hypertension in patients with severe heart failure is safe. Heart Failure Society of America (National Meeting –September 2013, Orlando, FL) Poster.
  • Bhatia N, Abushora MY, Stoddard MF. Saline Contrast Three-Dimensional Echocardiography for the Detection of Intrapulmonary Shunt and Patent Foramen Ovale. American Society of Echocardiography (National Meeting – June 2013, Minneapolis, MN) Poster.
  • Bhatia N, Abushora MY, Alnabki Z, Stoddard MF. Intrapulmonary Shunt: The Missing Link in Etiology of Cryptogenic Ischemic Stroke and Transient Ischemic Attack? American Society of Echocardiography (National Meeting – June 2013, Minneapolis, MN) Poster.
  • Bhatia N, Abushora MY, Alnabki Z, Stoddard MF. Intrapulmonary shunt is a potentially unrecognized cause of ischemic stroke and transient ischemic attack. American College of Physicians (National Meeting – April 2013, San Francisco, CA) Associates Clinical Science Research Project – Poster Finalist.
  • Bhatia N, Chaturvedi S. Sumatriptan Induced Hypertensive Episodes Presenting As Pseudophaeochromocytoma. American College of Physicians (National Meeting – April 2013, San Francisco, CA) Associates Clinical Vignette – Poster Finalist.
  • Chaturvedi S, Bhatia N. Not the usual suspect: Sirolimus pulmonary toxicity presenting as fever and dyspnea in the immune-compromised host". American College of Physicians (National Meeting – April 2013, San Francisco, CA Associates Clinical Vignette – Poster Finalist.
  • Bhatia N, Stoddard MF. Impact and predictors of non-circular left ventricular outflow tract shapes on estimation of severity of aortic stenosis by continuity equation. American College of Cardiology (National Meeting – March 2013, San Francisco, CA) Poster.
  • Bhatia N, Abushora MY, Alnabki Z, Stoddard MF. Intrapulmonary shunt is a potentially unrecognized cause of ischemic stroke and transient ischemic attack. American College of Cardiology (National Meeting – March 2013, San Francisco, CA) Poster.
  • Tavakoli V, Bhatia N, Stoddard MF, Amini AA. Fusion of Tissue Doppler and Speckle Tracking in Echocardiography Images: Comparison with Speckle Tracking Echocardiography. American College of Cardiology (National Meeting – March 2013, San Francisco, CA) Poster.
  • Burke, A.M. and Setters, B. Follow the polypharmacy leader: Education induced heart block in a frail elderly female after failed cardioversion. [Poster] American Geriatric Society, AGS, Annual Scientific Meeting 2012, Seattle, Washington.
  • Leucker TM, Ge ZD, Procknow J, Liu Y, Kersten JR. Two Models Of Endothelial Dysfunction: The Importance Of Intrinsic Cardioprotective Properties Of The Coronary Endothelium. American Heart Association (AHA/ ATVB) Meeting 2013, Buena Vista, Florida.
  • Ge ZD, Leucker TM, Procknow J, Liu Y, Du J, Paterson M, Shi Y, Warltier DC, Kersten JR. Tetrahydrobiopterin increases myocardial tolerance to ischemia/reperfusion injury in diabetes mellitus and hyperglycemia by preventing eNOS uncoupling. American Heart Association (AHA) Scientific Session, 2012, Los Angeles, California. Circulation. 126:A16892.
  • Leucker T, Setters B. CADASIL Disease. A Case Report of a Rare, Genetic Early Onset Dementia, American Geriatric Society (AGS) Meeting, 2012, Seattle, Washington.
  • Leucker TM, Pratt PF, Kersten JR, Jones SP. Endothelial Derived Cardioprotection Is Abolished By Hyperglycemia, National American College of Physician Meeting (ACP), 2011, New Orleans, Louisiana.
  • Leucker T, Pratt PF, Warltier DC, Kersten JR. Endothelial Derived Cardioprotection Is Abolished By Hyperglycemia, American Heart Association (AHA/ ATVB) Meeting, 2011, Chicago, Illinois.
  • Wendorf G and Vizuete J. The Differential Diagnosis of Gas and Bloating. American College of Gastroenterology Meeting, 2013, San Diego, California
  • G, Li X, Civelek C. Amiodarone toxicity mimicking metastatic lung disease and liver findings: The continuing diagnostic challenge. Poster presented at SNMMI 2013 Annual Meeting at the Vancouver Convention Centre, Vancouver, BC, Canada June 8-12, 2013.
  • Bhatt G, Li X, Civelek C. Variations in technique of solid meal gastric emptying study: Importance of procedure execution and compliance. Poster presented at SNMMI 2013 Annual Meeting at the Vancouver Convention Centre, Vancouver, BC, Canada June 8-12, 2013.
  • Bhatt G, Li X, Civelek C. Recognizing seromadesis to prevent false-positive PET-CT interpretations. American Society of Clinical Oncology (ASCO) 2013 Electronic Publication: e22084.

 

Regional Conferences

 

  • Ghotra AS, Bhatia N. TACE is not Safe! Society of General Internal Medicine (Southern Chapter - February 2013, New Orleans, LA) Poster.
  • Bhatia N, Cua Y. Recognizing complications of severe brain injury P.A.I.D. off. Society of General Internal Medicine (Southern Chapter - February 2013, New Orleans, LA) Poster (Master Educator session).
  • Chatterjee A, Bhatia N, Ghotra AS, Ouyang FY. Multinodular Vascular Goitre: A Highly Atypical Finding In A Case Of Autoimmune Polyendocrinopathy Type 2. Society of General Internal Medicine (Southern Chapter - February 2012, New Orleans, LA) Poster.

 

State-Wide Conferences

 

  • Rehman A, Rawasia WF, Chugh AR. Severe refractory hypoxemia in pulmonary embolism: An indicator for thrombolysis? 2012 Kentucky ACC (American College of Cardiology) Annual Meeting – 18th August 2012.
  • Haney M, Tukaye D. (2013). A stitch in time doesn’t always save nine: Rapid development of NYHA Class IV heart failure following mitral valve repair for infective endocarditis. Poster presented at: American College of Physicians Kentucky Annual Meeting/Research Louisville/American College of Cardiology Kentucky Annual Meeting; Louisville, KY.
  • Bhatia N, Vongooru H, Ikram S. Acute myocardial infarction and massive pulmonary embolus presenting as cardiac arrest: Initial rhythm as a diagnostic clue. American College of Physicians (Kentucky Chapter- September 2012, Louisville, KY) Poster.
  • Bhatia N, Chatterjee A, Ouyang FY, Stoddard MF. Cryptogenic Stroke: Need to reopen PFO debate for patients with pacemaker/ICD/Central Catheter. American College of Cardiology (Kentucky Chapter - October 2011, Lexington, KY) Poster.
  • Leucker TM, Ge ZD, Procknow J, Liu J, Shi Y, Bienengraeber M, Warltier DC, Kersten JR: Coronary Vascular Endothelial Tetrahydrobiopterin Protects Cardiomyocytes against Hypoxia-Reoxygenation Injury during Hyperglycemia. American College of Cardiology (ACC) Kentucky Chapter Meeting, 2012, Louisville, Kentucky.
  • Bhatt G, Li XF, Jain A, Sharma VK, Pan J, Rai A, Rai SN, Civelek AC. Evaluating the Normal variant F18-FDG uptake in the Lower Thoracic Spinal Cord Segments in Cancer patients without CNS malignancy. Kentucky Chapter of American College of Physicians, Annual meeting held on Sept. 12, 2012 in Louisville, KY.