Wenke Feng

Wenke Feng

Wenke Feng, Ph.D.

Wenke Feng, Ph.D.

  • Associate Professor of Medicine

502-852-6991 - Academic Office


  • B.Sc.: Shaanxi Normal University (Xi'an, China)

  • M.Sc.: Northwest University (Xi'an, China)

  • Ph.D.: Universitaet fuer Bodenkultur (Vienna, Austria)


Research Interests

  • Mechanisms of alcoholic liver disease

  • Mechanisms of nonalcoholic steatohepatitis

  • Tissue hypoxia and diabetic complications

Recent Publications

  • Wang Y, Kirpich I, Liu Y, Ma Z, Barve S, McClain C, Feng W: Lactobacillus rhamnosus GG treatment potentiates intestinal hypoxia-inducible factor, promotes intestinal integrity, and ameliorates alcohol-induced liver injury, Am. J. Pathol. 2011, 179:2866-75.

  • Wang Y, Liu Y, Sidhu A, Ma Z, McClain C, Feng W: Lactobacillus rhamnosus GG culture supernatant ameliorates acute alcohol-induced intestinal permeability and liver injury. Am J Physiol Gastrointest Liver Physiol. 2012, 303:G32-41.

  • Liu Y, Wang C, Wang Y, Ma Z, Xiao J, McClain C, Li X, Feng W: Cobalt chloride decreases fibroblast growth factor-21 expression dependent on oxidative stress but not hypoxia-inducible factor in Caco-2 cells. Toxicol Appl Pharmacol. 2012, 264:212-221.

  • Bull-Otterson L, Feng W, Kirpich I, Wang Y, Xin X, Liu Y, Gobejishvili L, Joshi-Barve S, Ayvaz T, Petrosino J, McClain C, Barve S: Metagenomic Analyses of Alcohol Induced Pathogenic Alterations in the Intestinal Microbiome and the Effect of Lactobacillus rhamnosus GG Treatment, PLoS One, 2013, 8:e53028.

  • Wang Y, Liu Y, Kirpich I, Ma Z, Wang C, Zhang M, Suttles J, McClain C, Feng W, Lactobacillus rhamnosus GG reduces hepatic TNFα production and inflammation in chronic alcohol-induced liver injury. J Nut Biochem, 2013, 24:1609-1615.