Swati Joshi-Barve

Swati Joshi-Barve

Swati Joshi-Barve, Ph.D.

Swati Joshi-Barve, Ph.D.

  • Assistant Professor of Medicine

502-852-6991 - Academic Office


  • B.Sc.: University of Poona (India)

  • M.Sc.: University of Poona (India)

  • Ph.D.: University of Kentucky


Research Interests

  • Mechanisms of alcoholic and nonalcoholic steatohepatitis, and hepatocellular carcinoma.

  • Mechanisms of alcohol-induced immune dysfunction.

  • Impact of acrolein and reactive aldehydes on liver disease.

Recent Publications

  • Bull-Otterson L, Feng W, Kirpich I, Wang Y, Qin X, Liu Y, Gobejishvili L, Joshi-Barve S, Ayvaz T, Petrosino J, Kong M, Barker D, McClain C, Barve S: Metagenomic analyses of alcohol induced pathogenic alterations in the intestinal microbiome and the effect of Lactobacillus rhamnosus GG treatment. PLoS One. 2013;8(1):e53028. PMID: 23326376.

  • Kirpich I, Zhang J, Gobejishvili L, Kharebava G, Barker D, Ghare S, Joshi-Barve S, McClain CJ, Barve S: Binge Ethanol-Induced HDAC3 Down-Regulates Cpt1α Expression Leading to Hepatic Steatosis and Injury. Alcohol Clin Exp Res. 2013 Jul 26. PMID: 23905631.

  • Mohammad MK, Avila D, Zhang J, Barve S, Arteel G, McClain C, Joshi-Barve S: Acrolein cytotoxicity in hepatocytes involves endoplasmic reticulum stress, mitochondrial dysfunction and oxidative stress. Toxicol Appl Pharmacol. 2012;265(1):73-82. PMID: 23026831.

  • Ghare S, Patil M, Hote P, Suttles J, McClain C, Barve S, Joshi-Barve S: Ethanol inhibits lipid raft-mediated TCR signaling and IL-2 expression: potential mechanism of alcohol-induced immune suppression. Alcohol Clin Exp Res. 2011;35(8):1435-44. PMID: 21463338.

  • Moghe A, Joshi-Barve S, Ghare S, Gobejishvili L, Kirpich I, McClain CJ, Barve S: Histone modifications and alcohol-induced liver disease: are altered nutrients the missing link? World J Gastroenterol. 2011;17(20):2465-72. Review. PMID: 21633651.