Ming Song, M.D., Ph.D.

Ming Song

  • Assistant Professor

502-852-1370 - Academic Office


  • M.D.: Binzhou Medical College (China)
  • M.S.: Capital University of Medical Sciences (China)
  • Ph.D.: Capital University of Medical Sciences (China)


Research Interests

  • Fructose and Fatty Liver
  • Spinal Cord Injury and Liver Disease
  • Nuclear Hormones and Liver Disease


Featured Publications

  • Prodhan MAI, Shi B, Song M, He L, Yuan F, Yin X, Bohman P, McClain CJ, Zhang X. Integrating comprehensive two-dimensional gas chromatography mass spectrometry and parallel two-dimensional liquid chromatography mass spectrometry for untargeted metabolomics. Analyst. 2019 Jun 13. doi: 10.1039/c9an00560a. [Epub ahead of print] PubMed PMID: 31192319.
  • He L, Wei X, Ma X, Yin X, Song M, Donninger H, Yaddanapudi K, McClain CJ, Zhang X. Simultaneous Quantification of Nucleosides and Nucleotides from Biological Samples. J Am Soc Mass Spectrom. 2019 Jun;30(6):987-1000. doi: 10.1007/s13361-019-02140-7. Epub 2019 Mar 7. PubMed PMID: 30847833; PubMed Central PMCID: PMC6520184.
  • Song M, Vos MB, McClain CJ. Copper-Fructose Interactions: A Novel Mechanism in the Pathogenesis of NAFLD. Nutrients. 2018 Nov 21;10(11). pii: E1815. doi: 10.3390/nu10111815. Review. PubMed PMID: 30469339; PubMed Central PMCID: PMC6266129.
  • Song M, Li X, Zhang X, Shi H, Vos MB, Wei X, Wang Y, Gao H, Rouchka EC, Yin X, Zhou Z, Prough RA, Cave MC, McClain CJ. Dietary copper-fructose interactions alter gut microbial activity in male rats. Am J Physiol Gastrointest Liver Physiol. 2018 Jan 1;314(1):G119-G130. doi: 10.1152/ajpgi.00378.2016. Epub 2017 Oct 12. PubMed PMID: 29025734; PubMed Central PMCID: PMC5866377.
  • Mendoza M, Caltharp S, Song M, Collin L, Konomi JV, McClain CJ, Vos MB. Low Hepatic Tissue Copper in Pediatric Nonalcoholic Fatty Liver Disease. J Pediatr Gastroenterol Nutr. 2017 Jul;65(1):89-92. doi: 10.1097/MPG.0000000000001571. PubMed PMID: 28644356; PubMed Central PMCID: PMC5492896.
  • Koo I, Kim S, Shi B, Lorkiewicz P, Song M, McClain C, Zhang X. EIder: A compound identification tool for gas chromatography mass spectrometry data. J Chromatogr A. 2016 May 27;1448:107-114. doi: 10.1016/j.chroma.2016.04.064. Epub 2016 Apr 23. PubMed PMID: 27131963.
  • Song M, Chen T, Prough RA, Cave MC, McClain CJ. Chronic Alcohol Consumption Causes Liver Injury in High-Fructose-Fed Male Mice Through Enhanced Hepatic Inflammatory Response. Alcohol Clin Exp Res. 2016 Mar;40(3):518-28. doi: 10.1111/acer.12994. Epub 2016 Feb 9. PubMed PMID: 26858005; PubMed Central PMCID: PMC5517020.
  • Wahlang B, Prough RA, Falkner KC, Hardesty JE, Song M, Clair HB, Clark BJ, States JC, Arteel GE, Cave MC. Polychlorinated Biphenyl-Xenobiotic Nuclear Receptor Interactions Regulate Energy Metabolism, Behavior, and Inflammation in Non-alcoholic-Steatohepatitis. Toxicol Sci. 2016 Feb;149(2):396-410. doi: 10.1093/toxsci/kfv250. Epub 2015 Nov 25. PubMed PMID: 26612838; PubMed Central PMCID: PMC4751229.
  • Wei X, Song M, Yin X, Schuschke DA, Koo I, McClain CJ, Zhang X. Effects of Dietary Different Doses of Copper and High Fructose Feeding on Rat Fecal Metabolome. J Proteome Res. 2015 Sep 4;14(9):4050-8. doi: 10.1021/acs.jproteome.5b00596. Epub 2015 Aug 7. PubMed PMID: 26216400; PubMed Central PMCID: PMC6545594.
  • Song M, Schuschke DA, Zhou Z, Zhong W, Zhang J, Zhang X, Wang Y, McClain CJ. Kupffer cell depletion protects against the steatosis, but not the liver damage, induced by marginal-copper, high-fructose diet in male rats. Am J Physiol Gastrointest Liver Physiol. 2015 Jun 1;308(11):G934-45. doi: 10.1152/ajpgi.00285.2014. Epub 2015 Mar 26. PubMed PMID: 25813056; PubMed Central PMCID: PMC4451322.