Education and Training

Ph.D.: University of Louisville, Physiology and Biophysics
Postdoctoral Fellowships: University of Louisville, Cardiovascular Medicine; Brigham and Women's Hospital/Harvard Medical School, Physiologic Chemistry and Immunology

Featured Publications

• Sansbury BE, Nystoriak MA, Uchida S, Wysoczynski M, Moore JB 4th. Rigor Me This: What Are the Basic Criteria for a Rigorous, Transparent, and Reproducible Scientific Study? Front Cardiovasc Med. 2022 Jul 1;9:913612. doi: 10.3389/fcvm.2022.913612. PMID: 35845053; PMCID: PMC9283916.
• Sugimoto S, Mena HA, Sansbury BE, Kobayashi S, Tsuji T, Wang CH, Yin X, Huang TL, Kusuyama J, Kodani SD, Darcy J, Profeta G, Pereira N, Tanzi RE, Zhang C, Serwold T, Kokkotou E, Goodyear LJ, Cypess AM, Leiria LO, Spite M, Tseng YH. Brown adipose tissue-derived MaR2 contributes to cold-induced resolution of inflammation. Nat Metab. 2022 Jun;4(6):775-790. doi: 10.1038/s42255-022-00590-0. Epub 2022 Jun 27. PMID: 35760872; PMCID: PMC9792164.
• Reeves AR, Sansbury BE, Pan M, Han X, Spite M, Greenberg AS. Correction: Myeloid-Specific Deficiency of Long-Chain Acyl CoA Synthetase 4 Reduces Inflammation by Remodeling Phospholipids and Reducing Production of Arachidonic Acid-Derived Proinflammatory Lipid Mediators. J Immunol. 2022 Jun 1;208(11):2593. doi: 10.4049/jimmunol.2200133. Epub 2022 May 16. Erratum for: J Immunol. 2021 Dec 1;207(11):2744-2753. PMID: 35577369.
• Reeves AR, Sansbury BE, Pan M, Han X, Spite M, Greenberg AS. Myeloid-Specific Deficiency of Long-Chain Acyl CoA Synthetase 4 Reduces Inflammation by Remodeling Phospholipids and Reducing Production of Arachidonic Acid-Derived Proinflammatory Lipid Mediators. J Immunol. 2021 Dec 1;207(11):2744-2753. doi: 10.4049/jimmunol.2100393. Epub 2021 Nov 1. Erratum in: J Immunol. 2022 Jun 1;208(11):2593. PMID: 34725110; PMCID: PMC8802997.
• Sadhu S, Decker C, Sansbury BE, Marinello M, Seyfried A, Howard J, Mori M, Hosseini Z, Arunachalam T, Finn AV, Lamar JM, Jourd'heuil D, Guo L, MacNamara KC, Spite M, Fredman G. Radiation-Induced Macrophage Senescence Impairs Resolution Programs and Drives Cardiovascular Inflammation. J Immunol. 2021 Oct 1;207(7):1812-1823. doi: 10.4049/jimmunol.2100284. Epub 2021 Aug 30. PMID: 34462312; PMCID: PMC8555670.
• Sansbury BE, Li X, Wong B, Riley CO, Shay AE, Nshimiyimana R, Petasis NA, Serhan CN, Spite M. PCTR1 Enhances Repair and Bacterial Clearance in Skin Wounds. Am J Pathol. 2021 Jun;191(6):1049-1063. doi: 10.1016/j.ajpath.2021.02.015. Epub 2021 Mar 6. PMID: 33689792; PMCID: PMC8176141.
• Weinstock A, Rahman K, Yaacov O, Nishi H, Menon P, Nikain CA, Garabedian ML, Pena S, Akbar N, Sansbury BE, Heffron SP, Liu J, Marecki G, Fernandez D, Brown EJ, Ruggles KV, Ramsey SA, Giannarelli C, Spite M, Choudhury RP, Loke P, Fisher EA. Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis. Elife. 2021 Mar 15;10:e67932. doi: 10.7554/eLife.67932. PMID: 33720008; PMCID: PMC7994001.
• Hosseini Z, Marinello M, Decker C, Sansbury BE, Sadhu S, Gerlach BD, Bossardi Ramos R, Adam AP, Spite M, Fredman G. Resolvin D1 Enhances Necroptotic Cell Clearance Through Promoting Macrophage Fatty Acid Oxidation and Oxidative Phosphorylation. Arterioscler Thromb Vasc Biol. 2021 Mar;41(3):1062-1075. doi: 10.1161/ATVBAHA.120.315758. Epub 2021 Jan 21. PMID: 33472399; PMCID: PMC8174560.
• Heffron SP, Weinstock A, Scolaro B, Chen S, Sansbury BE, Marecki G, Rolling CC, El Bannoudi H, Barrett T, Canary JW, Spite M, Berger JS, Fisher EA. Platelet-conditioned media induces an anti-inflammatory macrophage phenotype through EP4. J Thromb Haemost. 2021 Feb;19(2):562-573. doi: 10.1111/jth.15172. Epub 2020 Dec 3. PMID: 33171016; PMCID: PMC7902474.
• Sharma M, Schlegel MP, Afonso MS, Brown EJ, Rahman K, Weinstock A, Sansbury BE, Corr EM, van Solingen C, Koelwyn GJ, Shanley LC, Beckett L, Peled D, Lafaille JJ, Spite M, Loke P, Fisher EA, Moore KJ. Regulatory T Cells License Macrophage Pro-Resolving Functions During Atherosclerosis Regression. Circ Res. 2020 Jul 17;127(3):335-353. doi: 10.1161/CIRCRESAHA.119.316461. Epub 2020 Apr 27. PMID: 32336197; PMCID: PMC7367765.