Matthew Spite, Ph.D.

Assistant Professorof Medicine

Department of Medicine, Division of Cardiovascular Medicine


502-852-7215 matthew.spite@louisville.edu

Research Interests:

Inflammation is an underlying component of many prominent diseases, including atherosclerosis and diabetes. The major thrust of our research is to understand the mechanisms by which acute inflammation resolves in order to understand how these pathways could become modulated with the progression of chronic inflammatory diseases. In particular, we are interested in the role of endogenous lipid mediators, such as the lipoxins and resolvins, in actively regulating the resolution of inflammation. Our long-term goal is to determine if pro-resolution lipid mediators could serve as biotemplates for the development of novel therapeutics for treating cardiovascular disease.

Selected Publications: