Recent Publications
Benton RL, MA Maddie, DR Minnillo, T Hagg, SR Whittemore (2007) Identification and characterization of a specific subpopulation of angiogenic spinal microvessels binding the Griffonia simplicifolia isolectin B4 following traumatic spinal cord injury (SCI) in the adult mouse. J Comp Neurol (in press)
Cheng X, Y Wang, Q He, M Qiu, SR Whittemore & Q Cao, Down-regulation of Olig1 and Olig2 by BMP2 inhibits the differentiation and maturation of adult oligodendrocyte precursor cells (2007) Stem Cells (in press)
Cruz-Orengo L, JD Figueroa, A Torrado, A Puig, SR Whittemore & JD Miranda (2007) Reduction of EphA4 receptor expression after spinal cord injury does not induce axonal regeneration or return of tcMMEP responses, Neurosci Letts 418:49-54
Talbott JF, Q Cao, J Bertran, M Nkansah, RL Benton, E Lavik & SR Whittemore (2007) CNTF promotes the survival and differentiation of adult spinal cord-derived oligodendrocyte precursor cells in vitro but fails to promote remyelination in vivo, Exp Neurol 204:485-489
Willson CA, RD Foster, SM Onifer, SR Whittemore* & JD Miranda* (2006) EphB3 receptor and its ligand expression in the adult rat brain, J Molec Histol 37:369-80 (*co-communicating authors)
Cruz-Orengo L, JD Figueroa, I Velązquez, A Torrado, C Ortģz, C Hernąndez, A Puig, A Segarra, SRWhittemore & JD Miranda (2006) Blocking EphA4 upregulation after spinal cord injury results in enhanced chronic pain. Exp Neurol 202:421-33
Abdellatif AA, Pelt JL, Benton RL, Howard RM, Tsoulfas P, Ping P, Xu XM, Whittemore SR (2006) Gene delivery to the spinal cord: Comparison between lentiviral, adenoviral, and retroviral vector delivery systems, J Neuro Res 84:000-000 (Page Proofs)
Cruz-Orengo L, Figueroa JD, Velazquez I, Torrado A, Ortiz C, Hernandez C, Puig A, Segarra A, Whittemore SR, Miranda JD (2006) Blocking EphA4 upregulation after spinal cord injury results in enhanced chronic pain Exp Neurology (Page Proofs)
Enzmann GU, Benton RL, Talbott JF, Cao QL, Whittemore SR (2006) Functional considerations of stem cell transplantation therapy for spinal cord repair J Neurotrauma 23 (3/4): 479-495
Figueroa JD, Benton RL, Velazquez I, Torrado AI, Ortiz CM, Henandez CM, Diaz JJ, Magnuson DS, Whittemore SR, Miranda JD (2006) Inhibition of EphA7 up-regulation after spinal cord injury reduces apoptosis and promotes locomotor recovery J Neuro Res
Talbott JF, Cao WL, Enzmann GU, Benton RL, Achim V, Cheng XX, Mills MD, Rao MS, Whittemore SR (2006) Schwann cell-like differentiation by adult oligodendrocyte precursor cells following engraftment into the demyelinated spinal cord is BMP-dependent, Glia 54: 147-159
Benton RL, JP Woock, M Hetman, E Gozal, SR Whittemore: Intraspinal application of endothelin results in focal ischemic injury of spinal gray matter and restricts the differentiation of engrafted neural stem cells, Neurochem Res 30:809-823, 2005.
Cao Q, Xu X-M, DeVries WH, Enzmann GU, Ping P, Wood PM, Tsoulfas P, Bunge MB, Whittemore SR (2005) Functional recovery in traumatic spinal cord injury following transplantation of multineurotrophin-expressing glial precursor cells. J Neurosci 25:6947-6957
Irizarry-Ram¡rez M, CA Willson, I Vel zquez, H Jones, SR Whittemore & JD Miranda (2005) Upregulation of EphA3 receptor after spinal cord injury, J Neurotrauma 22:929-935
Enzmann GU*, RL Benton*, JP Woock, RM Howard, P Tsoulfas & SR Whittemore (2005) Consequences of noggin expression by glial and neuronal precursor cells engrafted into the injured spinal cord. Exp Neurol 195:293-304 (*these two authors contributed equally)
Cao Q, YP Zhang, C Iannotti, WH DeVries, XM Xu, CB Shields & SR Whittemore (2005) Functional and electrophysiological consequences of graded contusive spinal cord injury in the adult rat, Exp Neurol 191:S3-S16
Benton RL, GU Enzmann & SR Whittemore (2005) Stem cell grafting into the injured spinal cord, In: Synaptic Plasticity, M Baudry, Y Bi, S Schreiber, eds., Marcel Dekker, New York, pp 329-359
Loy DN, AE Sroufe, JL Pelt, DA Burke, Q-l Cao, JF Talbott & SR Whittemore (2005) Serum biomarkers for acute spinal cord injury: rapid elevation of neuron-specific enolase and S-100á, Neurosurgery 56:391-397
Talbott JF, DN Loy, Y Liu, MS Qiu, MB Bunge, MS Rao & SR Whittemore (2005) Endogenous Nkx2.2+/Olig2+ oligodendrocyte precursor cells fail to remyelinate the demyelinated adult rat spinal cord in the absence of astrocytes, Exp Neurol 192:11-24
Gajavelli S, Wood PM, Pennica D, Whittemore SR, Tsoulfas, P: BMP signaling initiates a neural crest differentiation program in embryonic rat CNS stem cells. Exp Neurol 188: 205-223, 2004.
Loy DN, Magnuson DSK, Zhang YP, Onifer SM, Mills MD, Cao QL, Darnall JB, Fajardo LC, Burke DA, Whittemore SR: Functional redundancy of ventral spinal locomotor pathways. J Neurosci 22:315-323, 2002.
Loy DN, Crawford CH, Darnall JB, Burke DA, Onifer SM, Whittemore SR: Temporal progression of angiogenesis and basal lamina deposition after contusive spinal cord injury in the adult rat. J Comp Neurol 445:308-324, 2002.
Willson CA, Irizarry-Ramírez M, Gaskins HE, Cruz-Orengo L, Figueroa JD, Whittemore SR, Miranda JD: Upregulation of EphA receptor expression in the injured adult rat spinal cord. Cell Transplant 11:229-239, 2002.
Cao QL, Onifer SM, Whittemore SR: Labeling stem cells in vitro for identification of their differentiated phenotypes after grafting into the CNS. In: Methods in Molecular Biology, vol 198: Neural Stem Cells: Methods and Protocols, Zigova T, Sanberg PR, Sanchez-Ramos J (eds). Humana Press, Totowa, NJ. Chapter 28, pp 307-318, 2002.
Whittemore SR, Zhang YP, Shields CB, Magnuson DSK: Optimizing stem cell grafting into the CNS. Ibid, Chapter 29, pp 319-325, 2002.
Cao QL, Benton RL, Whittemore SR: Stem cell repair of central nervous system injury. J Neurosci Res 68:501-510, 2002.
Loy DN, JF Talbott, SM Onifer, MD Mills, DA Burke, JB Darnall, LC Farajdo, DSK Magnuson & SR Whittemore: Both dorsal and ventral spinal cord pathways contribute to overground locomotion in the adult rat, Exp Neurol 177:575-580, 2002
Yang P, Seiler MJ, Aramant RB, Whittemore SR: In vitro isolation and expansion of human retinal progenitor cells. Exp Neurol 177:326-331, 2002.
Yang P, Seiler MJ, Aramant RB, Whittemore SR: Differential lineage restriction of rat neural retina precursor cells in vitro and in vivo. J Neurosci Res, 69:466-476, 2002.
Cao Q-L, Howard RM, Dennison, JB, Whittemore SR: Differentiation of engrafted neuronal restricted precursor cells is inhibited in the traumatically injured spinal cord. Exp Neurol 177:349-359, 2002.