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Kentucky Spinal Cord Injury Research Center

Position Openings

Current position openings within KSCIRC

NEW Postdoctoral Research Fellow (3 Positions- March 2008)

We are currently seeking three highly motivated Postdoctoral Research Fellows to join our team at the Kentucky Spinal Cord Research Center and the Department of Neurological Surgery in collaboration with the Neuroscience Collaborative Center at Frazier Rehab Institute. The areas of research focus include animal and human models of sensorimotor control of spinal locomotor circuits, activity-dependent neural plasticity, and recovery of cardiovascular function after spinal cord injury.

Candidates should have a Ph.D. in neuroscience, physiology, kinesiology, biomechanics, rehabilitation medicine, bioengineering or other related sciences with an academic record of scientific excellence, independent research, and a strong interest in an interdisciplinary approach to the study of neural control of locomotion and activity-based rehabilitation in spinal cord injury. The applicant will have opportunities to collaborate and work in the basic and human research core facilities. The Kentucky Spinal Cord Research Center and the Neuroscience Collaborative Research Center have excellent core facilities and a vibrant, interactive and collaborative scientific environment with a strong commitment to translate research findings to the clinic.

Applicants should submit a curriculum vita, list of publications, and e-mail address and telephone of 3 references.

Contact:

Susan Harkema, Ph.D.
Associate Professor and Rehabilitation Research Director, Owsley B. Frazier Chair in Neurological Rehabilitation
Department of Neurological Surgery and Kentucky Spinal Cord Injury Research Center

University of Louisville

Frazier Rehab Institute

220 Abraham Flexner Way

Louisville, KY 40202

502-581-8747 fax: 502-585-0406

susan.harkema@jhhs.org

Postdoctoral position in neuroprotection after spinal cord injury

A postdoctoral position is available immediately in the laboratory of Dr. Theo Hagg to investigate methods to pharmacologically rescue axons and myelin after a contusive spinal cord injury in adult rats and mice. This project is part of an NIH award focused on targeting the vasculature in the damaged spinal cord. Information about the lab located at our website.

These methods involve chronic intrathecal or intravenous infusion of novel drugs that enhance intracellular survival signaling and reduce infiltration of inflammatory cells after a contusion injury in adult mice or rats. The effectiveness of the treatments is measured by anterograde tracing of axons, histological analyses of spared myelin and blood vessels, analyses of inflammatory cells, by sensory and motor evoked potentials and behavioral measures. There is ample opportunity to interact and collaborate with other trainees in the lab, and with the other ~60 members of the Kentucky Spinal Cord Injury Research Center and to attend regular seminars from visiting leaders in various fields of neuroscience and neurotrauma. Our Center has excellent core facilities and a vibrant, interactive and collaborative scientific environment and a mission to translate our research to the clinic.

The candidates should have a PhD plus relevant published research experience. Desired backgrounds include neurobiology, basic molecular biology, pharmacology and rodent neurosurgery. Applicants who have experience with spinal cord injury models are preferred. The ability to communicate effectively in English is a must. US citizens or green card holders are preferred.

Salary will be based on experience.

Louisville is a pleasant mid-sized city with many cultural and outdoors opportunities, and relatively inexpensive housing.

E-mail CV and e-mail addresses of 3 references, including that of the current supervisor, to theo.hagg@louisville.edu

Postdoctoral position

Regulation of CNTF-mediated adult CNS neurogenesis for stroke treatments

A postdoctoral position is available immediately in the laboratory of Dr. Theo Hagg to investigate methods to pharmacologically induce CNTF levels in the CNS of adult mice and thereby induce neurogenesis for cell replacement in a stroke model. This is project is part of brand new 5 year NIH award. Information about the lab is located at our web site

These methods involve systemic and stereotaxic intracerebral injections of pharmaceutical drugs in adult mice, applying novel treatments to mice with a stroke induced by middle cerebral artery occlusion. Knockout mice are used for certain projects. Analyses include real time quantitative RT-PCR, Western blotting, and histology for proliferating cells, neuroblasts and neurons derived from the subventricular zone of the forebrain. There is ample opportunity to interact and collaborate with other postdocs in the lab, and with the other ~60 members of the Kentucky Spinal Cord Injury Research Center and to attend regular seminars from visiting leaders in various fields of neuroscience and neurotrauma. Our Center has excellent core facilities and a vibrant, interactive and collaborative scientific environment and a mission to translate our research to the clinic.

The candidates should have a PhD or an MD plus relevant published research experience. Desired backgrounds include: neurobiology, pharmacology, basic molecular biology and rodent neurosurgery. Evidence of experience with unbiased stereological analyses of adult neurogenesis and/or the intraluminal MCAO model would be a plus. The ability to communicate effectively in English is a must. US citizens or green card holders are preferred.

Salary will be based on experience.

Louisville is a pleasant mid-sized city with many cultural and outdoors opportunities, and relatively inexpensive housing.

E-mail CV and e-mail addresses of 3 references, including that of the current supervisor, to theo.hagg@louisville.edu

POSTDOCTORAL POSITION TO STUDY MOLECULAR MECHANISMS OF NEURONAL DEATH AND SURVIVAL

Location: Hetman laboratory, Kentucky Spinal Cord Injury Research Center, University of Louisville, USA
Salary: commensurate with experience
Description: A position is available to investigate the mechanisms underlying neuronal death and survival.
Eligibility: Ph.D. or equivalent degree. Desired backgrounds include neurobiology and/or molecular biology (DNA repair, signal transduction or transcriptional regulation).
Contact: send curriculum vitae, publication list and names, e-mail address, telephone and fax numbers of 2-3 references as an attached file in Microsoft Word Rich Text Format to michal.hetman@louisville.edu OR per regular mail to Dr. Michal Hetman, Kentucky Spinal Cord Injury Research Center, 511 S. Floyd Str., MDR Room 616, Louisville KY 40292. For more information about the Hetman lab, please visit our website.

Postdoctoral Position in CNS Stem Cell Repair
Postdoctoral Fellow position available examining the role of neural stem cells to repair the damaged spinal cord. The project involves genetically modifying various stem cell populations in vitro and then grafting them into mouse spinal cord injury models. The successful candidate should have a Ph.D., and/or M.D. Relevant research experience in molecular biology, mammalian cell culture, small animal microsurgery, histology, and/or microscopy is desirable, but not all are essential. The KSCIRC is a highly collaborative research center with outstanding core facilities. For further information, visit our website. Salary is highly competitive and commensurate with experience.

Email CV and contact information for 3 references to:
Dr. Scott R. Whittemore
Henry D. Garretson Professor of Neurological Surgery
Scientific Director, KSCIRC
swhittemore@louisville.edu