Kentucky Spinal Cord Injury Research Center

G. Kharebava, D. Makonchuk, K. Kalita, J.J. Zheng, M. Hetman (2008) Requirement of 3-phosphoinositide-dependent protein kinase-1 (PDK1) for BDNF-mediated neuronal survival. J. Neurosci. 28(44):11409-11420. (PDF file available through  http://www.jneurosci.org)

A. Gozdz, A. Vashishta, K. Kalita, E. Szatmari, J.J. Zheng, S. Tamiya, N. Delamere, M. Hetman. Cisplatin-mediated activation of extracellular signal-regulated kinases 1/2 (ERK1/2) by inhibition of ERK1/2 phosphatases. (2008) J. Neurochem. 106:2056-2067. (available online at Pubmed)

K. Kalita, D. Makonchuk, C. Gomes, J.J. Zheng, M. Hetman. Inhibition of nucleolar transcription as a trigger for neuronal apoptosis. (2008) J. Neurochem. 105:2286–2299.(PDF file available  through JNC Online)

E.Szatmari, K.Kalita , G.Kharebava, and M.Hetman. Role of Kinase Supressor of Ras-1 in neuronal survival signaling by extracellular signal-regulated kinase 1/2. (2007) J.Neurosci. 27:11389-11400 (PDF file available through  http://www.jneurosci.org)

K.Kalita, G.Kharebava, J.Zheng, and M.Hetman. Role of MKL1 in ERK1/2-dependent stimulation of SRF-driven transcription in response to BDNF or increased synaptic activity. (2006) J.Neurosci. 26: 10020-10032 (PDF file available through  http://www.jneurosci.org)

M.Hetman, G.Kharebava.  Survival signaling pathways activated by NMDA receptors. (2006) Current Top. Med. Chem. 6: 787-799 (click here to download a pdf file containing the manuscript)

A.Habas, G.Kharebava, E.Szatmari, and M.Hetman. NMDA neuroprotection against a Phosphatidylinositol-3 Kinase inhibitor, LY294002 by NR2B-mediated suppression of Glycogen Synthase Kinase-3beta-induced apoptosis. (2006) J.Neurochem. 96: 335-348 (PDF file available  through JNC Online)

E.Szatmari, A.Habas, P.Yang, J.J.Zheng, T.Hagg and M.Hetman. A positive feedback loop between glycogen synthase kinase 3beta and protein phosphatase 1 after stimulation of NR2B NMDA receptors in forebrain neurons. (2005) J.Biol.Chem. 280: 37526-37535 (PDF file available  through http://www.jbc.org)