Michal Hetman, M.D., Ph.D.

Assistant Professor, Department of Neurological Surgery and Department of Pharmacology & Toxicology

Endowed Professor of Molecular Signaling

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Laboratory of Neurosignaling

Research Overview

Pathologies of the nervous system including  traumatic injuries and neurodegenerative diseases are accompanied by neuronal cell death and dysfunction. The resulting loss of cell bodies, synapses, and cellular processes is thought to underlie neurological deficits occurring in these conditions. Therefore, therapeutic interventions to enhance neuronal survival and to preserve their morphological complexity may prevent development of deleterious neurological symptoms. The research in my laboratory is concentrated on identification of molecules controlling neuronal survival and maintenance of their functional and morphological integrity. My particular interests are in:   Area 1- Role of Nucleolus in Neuronal Health and Disease, and, Area 2- Signaling Pathways that Mediate NMDA Receptor-dependent Neuronal Survival.