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Michal Hetman, M.D., Ph.D.

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Michal Hetman, M.D., Ph.D.

Assistant Professor, Department of Neurological Surgery and Department of Pharmacology & Toxicology

Endowed Professor of Molecular Signaling


Recent Publications
Laboratory of Neurosignaling

Research Overview

Pathologies of the nervous system including  traumatic injuries and neurodegenerative diseases are accompanied by neuronal cell death and dysfunction. The resulting loss of cell bodies, synapses, and cellular processes is thought to underlie neurological deficits occurring in these conditions. Therefore, therapeutic interventions to enhance neuronal survival and to preserve their morphological complexity may prevent development of deleterious neurological symptoms. Conversely, excessive growth of neurons may also lead to pathologies including epilepsy or neuropathic pain. The research in my laboratory is concentrated on identification of molecules controlling neural cell survival and  growth. My particular interests are in the role of a nuclear substructure, the nucleolus in stress sensing and cell growth in the nervous system. I am also interested in identifying signaling pathways that are critical for neural cell survival and growth control.     

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« October 2014 »
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