P30 Pilot Grants

In 2011, the Kentucky Spinal Cord Injury Research Center (KSCIRC) received an NIH/NCRR-funded P30 grant RR031159 - Mechanisms of plasticity and repair after spinal cord injury. The objective of this grant is to support KSCIRC core facilities including the animal surgery core, the behavioral and electrophysiological assessment core, the imaging core and the human rehabilitation and physiology assessment core. A description of those cores can be found at http://louisville.edu/kscirc/KSCIRC-neuroscience-cores. These facilities offer a unique opportunity to UofL investigators to perform neurotrauma research of the highest quality without a need for a lengthy process of adapting new technologies in their laboratories. To enable UofL investigators to take full advantage of the cores, a pilot grant program has been funded as a part of RR031159. The goal of the Pilot Grant Program is to encourage new research programs in the neurotrauma field and facilitate acquisition of preliminary data for subsequent extramural funding. The pilot program is directed to UofL Principal Investigators from outside the KSCIRC but KSCIRC PIs may participate as co-Investigators. The focus of the RFA can include, but is not limited to: 

(i) new technologies to monitor neurotrauma (pathology/physiology/behavioral outcomes),  

(ii) new hypotheses on the pathogenesis of neurotrauma, 

(iii) new therapies/approaches for neurotrauma/neurorepair/neurorehabilitation,

(iv) new technologies to deliver genes/drugs to cellular targets that are relevant for neurotrauma pathology/neurorepair, 

(v) new assistive technologies directed to neurotrauma patients.      

Budgets of up to $22,500 for a total period of 12 months can be requested. No PI salary support is allowed. An additional year of funding may be also considered by a competitive renewal mechanism (but would compete against all new proposals). No-cost extensions may be requested. No budget is required for submission.

Applications will include the following sections: specific aims, background and significance, experimental plan, innovation statement, references, NIH biosketches for the PI and key personnel, administrative statements on the use of human subjects, biohazardous agents and/or animals. No appendices will be allowed. The first four sections will be limited to 3 pages formatted according to the NIH-style standard. 

In addition, all junior faculty (Instructors and Assistant Professors) will be required to include an additional paragraph (that does not count in the 3 page limit) describing a mentoring plan which must identify a senior funded UofL faculty mentor with relevant expertise in the research area covered by the proposal and a schedule of meetings with that mentor. No senior faculty that serves as a mentor can be a Co-Investigator on that grant. The mentor must be willing to pre-review applicant’s manuscripts and grant proposals that will be generated using results from the pilot project. The mentor’s NIH Biosketch should be also included in the application. 

The deadline to submit proposals is April 18, 2014 at 11:59 PM with funding beginning June 1, 2014. The proposals should be submitted electronically to Mrs. Ruth O’Bryan (raobry02@louisville.edu). Grants will be evaluated by the members of the KSCIRC COBRE P30 External Advisor Board using the NIH 1-9 scale. 

(i) A standard NIH-style progress report will be required within 1 month following the end of the funding period. 

(ii) Researchers funded by the program will be required to present an annual seminar during the KSCIRC seminar series. In addition, they will be encouraged to present the results at the poster session during the annual Louisville Neuroscience Day.

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