You are here: Home Recent Awards

Recent Awards

by Wittliff,James L. last modified Dec 17, 2009 10:36 AM

Noteworthy Awards from IMD3 Faculty Members and their Team

Grant Awards - Invited Lectures - Student Awards - Recent Patents


Grant Awards:

Borchman Laboratory

  • New Grant Entitled "Tear Film Lipids and Dry Eye," from the National Eye Institute/NIH, RO1 ( G.N. Foulks, PI & D.B. Co-I)

  • New Grant Entitled "Azasite, Dry Eye and Meibum Lipids," from the Inspire Pharmaceuticals (G.N. Foulks, PI & D.B  Co-I)

 

Kakar Laboratory

  • New Grant Entitled " MerTK regulation of the RPB phagocytosis", (Qingxian Lu, PI and SS K,Co-PI)

  • New Grant Entitled "Development of Targeted Therapy for Cancer Treatment"  from the POCG, Office of Technology Transfer, University of Louisville  (SS Kakar, PI)

 

Pack Laboratory

  • 2008-2011    DoD Army Research Office USAMRAA Grant10243153 (7/2009-6/2012) “Acquisition of High Field Nuclear Magnetic Resonance Spectrometers for Research in Molecular Structure, Function and Dynamics” , role: PI
  • 2008-2011    DOE grant DE-FG02-08CH11538 (10/2008 - 9/2011) "Acquisition of High Field Nuclear Magnetic Resonance Spectrometers for Research in Molecular Structure, Function and Dynamics."  role: PI

 

 

Wittliff Laboratory

  • Department of Defense, Pre-Doctoral Trainee Fellowship to Traci L. Kruer, PI, (James L. Wittliff, Mentor), Functional Characterization of an ERE-Binding Protein as a Clinically Relevant Biomarker of Breast Cancer Behavior
  • Xceed Molecular Corp., Toronto, Ontario, Canada, JLW, PI, Research Service Agreement, Gene Expression Profiling of Breast Carcinoma:  Pilot Investigation of a Gene Subset. 
  • New Grant Entitled "Mathematical Model of Parotid Acinar Differentiation," from the National Institute of Dental and Craniofacial Research/NIH, R01, (Douglas Darling, PI, , James L. Wittliff, Co-I.)

 

Invited Lectures:

Borchman Laboratory

  • Invited Lecture entitled "Tear lipid-protein Interactions"  Meibomian Gland Dysfunction at the Dry Eye Symposium in Fort Lauderdale, FL, May 2009.

  • Invited Lecture entitled "Tear Lipids and Dry Eye"  at the Solving Dry Eye - An International Exchange in Sidney Australia. August 2009.

 

Fernandez-Botran Laboratory

  • Lecture entitled  "Recent Advances in the Immunology of Cancer," National Institute for Cancer (Instituto Nacional del Cáncer - INCAN).
  • Lecture entitled "Equilibrium in the Immune System - From Autoimmunity to Cancer," Universidad Francisco Marroquín (Medical School).
  • Lecture entitled " Genes and Cancer," Universidad Rafael Landívar (Medical School).
  • Lecture entitled "Recent Advances in the Immunology of Cancer," Actualization Symposium on Immunology and Microbiology (School of Biological Chemistry,  Universidad San Carlos de Guatemala).

 

 

Kang Laboratory

  • Invited Lecture entitled “Application of Nanoparticles for Disease Diagnosis and Treatment” at the University of South Florida, Tampa, FL, February 2009.

  • Invited Lecture entitled “When Nano Meets Bio” at the Annual IMD3 Symposium, Jewish Hospital in Louisville, KY, March 2009.

  • Invited Lecture entitled “Nano-Particles for Disease Diagnosis and Treatment” at the Presentation for Nanoday 2009, Louisville Science Center in Louisville, KY, April 2009.

 

Kakar Laboratory

  • Department of Biochemistry and Molecular Biology, U of L, "Emerging role of securin in biology and cancer," March 2008.

  • Division of Endocrinology and Metabolism, U of L, "Implication of nanotechnology in treatment of cancer," April 2008.

  • Division of Endocrinology and Metabolism, U of L, "Sensitivity of miRNA in ovarian cancer," April 2008.

  • Nanotechnology Symposium: Advances in Nanotechnology and Applications, "Implication of gold nano particles in the treatment of ovarian cancer"  Sullivan University, Louisville, October 2008.
  • International Symposium on Prognostic and Predictive Factors in Cancer management, "Targeted Therapy for Cancer,"  Lucknow, India, December 2008. 
  • International Conference on Translational Pharmacology and 41st Annual Conference of Indian Pharmacology, "Securin regulates tumor angiogenesis and metastasis," Delhi, India, December, 2008.
  • Society of Biological Chemists (India) Karnal Chapter and National Dairy Research Institute,"Securin and Tumorigenesis," Karnal, India. December 2008.
  • James Graham Brown Cancer Center, U of L, "Role of securin in tumor angiogenesis and metastasis," May 2009.

  • Medical Oncology/Hematology Fellowship Research seminar Series/Journal Club. "Small interfering RNA and Cancer," Feburary 2009.
  • Digoxin in Lung Cancer Therapy: A Biphasic Concentration-Dependent Response May Explain Discrepancies in Reported Studies. Edward P. Womack, MS, MT(ASCP) Senior Medical Technologist. Co-authroed with R. Valdes Jr, AACC, Chicago, IL.   
  • Plasma Concentrations of Adiponectin Hormone in Type 1 and Type 2 Diabetes.
    Sean L. Barnes, M.D., Ph.D. Chief Clinical Chemistry Fellow. Co-authored with M. Bon Homme, W. Tucker, R. Valdes, Jr.  and SA Jortani, AACC, Chicago, IL.
  • An Alternate Approach for Detection of Acetylsalicylic Acid Ingestion. William Tucker, Senior Research Technician.  Co-authored with J. Parker, EP Womack, B. Holland, J. Bishop, A. Gamboa, R. Chanchico, GM Bosse and SA Jortani, AACC, Chicago, IL.

 

Wittliff Laboratory

  • Invited Lecture entitled  “Laser Capture Microdissection for Molecular Analysis.”  The Histochemical Society Annual Meeting, San Diego, CA, April 5-7, 2008
  • Keynote Presentation:  Molecular Target & Diagnostics:  Critical Role of Sample Preparation in Discovery, G.O.T. Summit, Cambridge Healthtech Institute, Hilton Boston Logan Airport, Boston, MA, May 19, 2008
  • Invited lecture entitled “Laser Capture Microdissection:  A Contemporary Tool for Molecular Pathology,” XIII International Congress of Histochemistry and Cytochemistry, Gdansk, Poland, August 24, 2008
  • Invited Lecture entitled    “Expression and Clinical Relevance of Zinc-Finger Proteins in Cancer Cells.” XIII International Congress of Histochemistry and Cytochemistry, Gdansk, Poland, August 25, 2008
  • Invited Lecture entitled  Predicting Breast Cancer Outcome with Gene Expression Signatures on the Ziplex System, Corporate Workshop presented by Xceed Molecular at the  14th Annual Meeting of the Association for Molecular Pathology, Grapevine, Texas, October 30, 2008
  • Invited Lecture entitled    Critical Role of Sample Preparation in Discovery:  Diagnostics and Molecular Targets. Invitrogen 2008 Current Topics entitled “Current Topics in Cloning and Protein Expression,” San Diego, CA, November 4-7, 2008
  • Invited Lecture entitled “Tissue-Based Genomics for Predicting Clinical Behavior.”  IVF Clinic, Bregenz, Austria, November 24, 2008

 

Valdes Laboratory

  • Dr. Roland Valdes, Jr. and Dr. Saeed Jortani received plaques in recognition of their being “Founding Fathers” of the newly formed Clinical Proteomics Division of the American Association for Clinical Chemistry (AACC, Chicago, IL).

 

Student Awards:

Borchman Laboratory

  • Shelley Kakar, University of Louisville Undergraduate Research Fellow,  Project Title, "Raman spectrosdcopic characterization of human meibum in donors with meibomian gland dysfunction."

  • Sung-Hye Kim, University of Louisville, Undergraduate Research Scholar, Project Title  "Tear lipid-protein interactions that contribute to dry eye disease."

  • John McKay,  Summer Research Scholar Program, University of Louisville, Medical School Fellowship.

  • Edwin S. Ambrinck, Summer Research Scholar Program, University of Louisville, Medical School Fellowship. 

  • Sara Ratlif, Undergraduate Research Fellow,  KBRIN grant, Univeristy of Louisville.

 

Kang Laboratory

  • Wang, J., O’Toole, M.G., Massey, A., Biswas, W., Nantz, M., Achilefu, S., and Kang, K.A., “Highly specific, NIR fluorescent contrast agent with emission controlled by gold nanoparticle,” Duane F. Bruley Award, 2009 Annual ISOTT Conference, July 5-9, 2009, Cleveland, OH.

  • Wang, J.: IMD3 Travel Award for 2008 Annual Conference for AIChE, Philadelphia, PA, November, 2008.

 

Maurer Laboratory

  • T. Michael Sabo was awarded an Alexander von Humboldt Fellowship for Post-Doctoral studies with Professor Christian Griesinger at the Max Planck Institute for Biophysical Chemistry in Göttingen, Germany.   His research position starts in August 2009. 
  • Marina Malovichko received an IMD3 Travel Award in July 2009. A poster on the conformational changes that thrombin undergoes upon binding exosite-directed ligands was presented in Boston at the XXII Congress of the International Society of Thrombosis and Haemostasis (07/11/09-07/16/09). 
  • Whitney Goldsberry was an awarded a 2009 IMD3 Summer Fellowship to pursue studies characterizing interactions between thrombin and Factor XIII activation peptides. Results collected this summer will be included in her Senior Honors Thesis. 
  • Ricky Woofter was selected to serve a second year (2009-2010) as a Graduate Fellow for the Groundwork Education in Mathematics and Science (GEMS) program funded by the National Science Foundation GK-12 Program.  This program involves a collaborative effort between the University of Louisville and the Jefferson County Public Schools.

 

Wittliff Laboratory

  • Kruer, TL, Kerr, D.A. II, Wittliff, JL.  Expression of Novel Estrogen-Response-Element Binding Proteins in Human Breast Carcinoma Predicts Clinical Behavior.  American Association of Clinical Chemistry Translating Proteomic Discoveries into Clinical Diagnostics, Seattle, WA, May 8-13, 2008,    (First Place Poster Award)
  • Andres, SA, Smolenkova, IA, Wittliff, JL.  Levels and Distribution of Gene Expression with a Breast Cancer Prognostic Signature.  Research!Louisville 2008, GRD-11, October 20-24, 2008.  (Second Place Awardee)
  • Kruer, TL. Second place poster presentation at the 2009 IMD3 Syposium.
  • Kruer, TL, Kerr II, DA, Wittliff, JL.  Expression of Novel Estrogen-Response-Element Binding Proteins in Human Breast Carcinoma Predicts Clinical Behavior.  Research!Louisville 2008, GRD 27, October 20-24, 2008.  (Third Place Awardee)
  • Andres, SA. Finalist in Post-doctoral Research Poster Presentation at Research! Louisville 2009.
  • Andres, SA. Recipient of AACR Scholar-in-Training Award funded by Susan G. Komen for the Cure to attend the San Antonio Breast Cancer Symposium 2009.

 

Kakar Laboratory

  • IMD3 Travel Award to Dr. Parag P. Shah (post-doc fellow) to attend AACR meeting in Denver, Colorado.

 

Valdes Laboratory

  • Mohammad Al-Ghoul, Ph.D., won the "Best Oral Presentation" award for his presentation titled: "DLIF is Cytotoxic to Breast Cancer Cells: A novel Mechanism for Prevention of Breast Malignancies" at the 11th International Congress of the IATDMCT held in Montreal, 2009.
  • Geffen School of Medicine, Center for Health Sciences, Department of Pathology and Laboratory Medicine, Los Angeles.
  • Deanna Franke, Ph.D., DABCC is a Clinical Scientist with Pathology Consultants of South Broward, LLP in Hollywood Florida.
  • Pamela Steele, Ph.D. has joined the Marshfield Clinic in Marshfield, Wisconsin as a Clinical Chemist. 
  • Mohammad Al-Ghoul, Ph.D., Senior Research Associate, has received a Postdoctoral Fellowship in Environmental Health Sciences that is funded by NIEHS grant T232-ES11564 from the offices of Dr. David Hein and commencing July 1, 2009.
  • The ComACC-accredited Clinical Chemistry Fellowship Program has welcomed Mark P. Borgman, Ph.D. Dr. Borgman received his Ph.D. in Pharmaceutical Sciences at the University of Maryland, Baltimore. He joined our two-year program July 1.
  • Mohammad Al-Ghoul, Ph.D. Senior Research Associate, received the AACC’s Proteomics Division Best Abstract Award for his abstract titled Endogenous DLIF prompted apoptosis in breast cancer cells, Chicago, IL.

 

 

Recent Patents:

Bates Laboratory

  • Title: "Method for the Diagnosis and Prognosis of Malignant Diseases." This patent will help better diagnose and treat cancers at the molecular and cellular level.

 

Kakar Laboratory

  • Methods for Targeting Cancer Treatment and Detection. International Patent application filed in June, 2009.

 

 Miller Laboratory

  • Title: "Method for the Diagnosis and Prognosis of Malignant Diseases." This patent will help better diagnose and treat cancers at the molecular and cellular level.

Pierce Laboratory

  • WM Pierce, Jr., LC Waite and KG Taylor.  "Bone Targeting Compounds for Delivering Agents to the Bone for Interaction Therewith."  U.S. Patent 7,196,220.  Issued March 27, 2007.
  • WM Pierce, Jr., LC Waite and KG Taylor US Patent Application 12/036,057.  "Methods and Compounds for the Targeted Delivery of Agents to Bone for Interaction Therewith  (Generation 2)." May 2008.
  • WM Pierce, Jr., LC Waite and KG Taylor US Patent Application 12/043,904.   "Methods and Compounds for the Targeted Delivery of Agents to Bone for Interaction Therewith  (Generation 3)."  May 2008.
  • WM Pierce, Jr., LC Waite and KG Taylor - "Bone targeting compounds for delivering agents to bone for interaction therewith (II)." US Patent 7,399,789.  Issued on July 15, 2008

 

Taylor Laboratory

  • WM Pierce, Jr., LC Waite and KG Taylor.  "Bone Targeting Compounds for Delivering Agents to the Bone for Interaction Therewith."  U.S. Patent 7,196,220.  Issued March 27, 2007.
  • WM Pierce, Jr., LC Waite and KG Taylor US Patent Application 12/036,057.  "Methods and Compounds for the Targeted Delivery of Agents to Bone for Interaction Therewith  (Generation 2)." May 2008.
  • WM Pierce, Jr., LC Waite and KG Taylor US Patent Application 12/043,904.   "Methods and Compounds for the Targeted Delivery of Agents to Bone for Interaction Therewith  (Generation 3)."  May 2008.
  • WM Pierce, Jr., LC Waite and KG Taylor - "Bone targeting compounds for delivering agents to bone for interaction therewith (II)." US Patent 7,399,789.  Issued on July 15, 2008

 

Trent Laboratory

  • Title: "Method for the Diagnosis and Prognosis of Malignant Diseases." This patent will help better diagnose and treat cancers at the molecular and cellular level.
  • Title: "Family of PFKFB3 Inhibitors with Anti-Neoplastic Activities." Company: Advanced Cancer Therapeutics These researchers have identified compounds that starve cancer cells by blocking their use of glucose, stopping the cancer’s growth.
  • Title: "Discovery of a Novel Small Molecular Antagonist of MIF." Company: Advanced Cancer Therapeutics LLC The researchers have identified a small-molecule compound that allows large white blood cells known as macrophage to work properly. When they do not function properly, the consequences can be tumor growth, the spread of cancer cells and the abnormal development of blood vessels in tumors.

 

Wittliff Laboratory

  • James L. Wittliff and Sarah A. Andres.  Methods for Identifying an Increased Likelihood of Recurrence of Breast Cancer.  International Patent Application No. PCT/US2008/006963, date of filing June 3, 2008.
  • James L. Wittliff, Technology License to Xceed Molecular Corp, Toronto, Canada, ULRF Research Disclosure 07048, Gene Expression Profiles Predicting Clinical Behavior of Breast Cancer.  U.S. Provisional Patent Application No. 60/933,091, date of filing June 4, 2007 and full patent No. PCT/US2008/006963, date of filing June 3, 2008 (James L. Wittliff & Sarah A. Andres).
  • James L. Wittliff and D. Alan Kerr II.  Methods of Predicting Disease-Free and Overall Survival of Estrogen Receptor Positive Breast Cancer.  U.S. Provisional Patent Application No. 61/105,297, date of filing October 14, 2008.

 

 

 

Document Actions
Personal tools