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David J. Samuelson, Ph.D.

by Wittliff,James L. last modified Oct 26, 2010 03:58 PM

Assistant Professor of Biochemistry & Molecular Biology

SammuelsonEmail David Samuelson
Phone Number: 502-852-7797 (Office)
Fax Number: 502-852-6222
Address: University of Louisville               
Department of Biochemistry and Molecular Biology
HSC- A Bldg, Room 708
319 Abraham Flexner Way       
Louisville, KY  40202
Ph.D. University of Arizona

Postdoc McArdle Laboratory for Cancer Research, University of Wisconsic-Madison

 

Additional Appointments:

  • Assistant Professor, Department of Biochemistry and Molecular Biology, University of Louisville
  • Member, James Graham Brown Cancer Center
  • Member, Center for Genetics and Molecular Medicine
  • Member, Institute for Molecular Diversity and Drug Design
  • Member, Center for Environmental Genomics and Integrative Biology

 

Research Interests:

  • Breast cancer susceptibility and comparative genetics


Investigators:

  • Aaron DenDekker, Graduate Student
  • Jennifer Sanders, Graduate Student
  • Bharat Devapatla, Post-Doc
  • Xiu Xu, Post Doc
  • Aaron Puckett, Technician

 

Selected Publications:

  1. Samuelson DJ, Hesselson SE, Aperavich BA, Zan Y, Haag JD, Trentham-Dietz A, Hampton JM, Mau B, Chen K, Baynes C, Khaw KT, Luben RN, Perkins B, Shah M, Pharoah PD, Dunning AM, Easton DF, Ponder BA, and Gould MN.  Rat Mcs5a is a compound QTL with orthologous human loci that associate with breast cancer risk.  Proc Natl Acad Sci U S A.  2007; 104: 6299-304.
  2. Samuelson DJ, Aperavich BA, Haag JD, Gould MN. Fine Mapping Reveals Multiple Loci and a Possible Epistatic Interaction within the Mammary Carcinoma Susceptibility Quantitative Trait Locus, Mcs5.  Cancer Res. 2005; 65: 9637-42.
  3. Haag JD, Shepel LA, Kolman BD, Monson DM, Benton ME, Watts KT, Waller JL, Lopez-Guajardo CC, Samuelson DJ, Gould MN. Congenic rats reveal three independent Copenhagen alleles within the Mcs1 quantitative trait locus that confer resistance to mammary cancer. Cancer Res. 2003; 63: 5808-12.
  4. Samuelson DJ, Haag JD, Lan H, Monson DM, Shultz MA, Kolman BD, Gould MN. Physical evidence of Mcs5, a QTL controlling mammary carcinoma susceptibility, in congenic rats. Carcinogenesis 2003; 24: 1455-60.

 

Selected Abstracts:

  1.  David J. Samuelson, Xin Xu, Aaron den Dekker, Jennifer Sanders, Derek Vaughn, Courtney Lambring, and Aaron Puckett.  Comparative Environmental Genomics of Common Breast Cancer Susceptibility Alleles.  NIH/NIEHS Center Director’s Meeting, 2010.
  2. denDekker AD, Puckett AH, Vaughn MD, Lambring CJ, and Samuelson DJ.  Rat Mcs1b is a mammary gland autonomous QTL and an ortholog of a breast cancer susceptibility locus on human chromosome 5q.  Rat Genomics & Models Annual Meeting, Cold Spring Harbor Laboratory, 2009.
  3. Smits, BMG, Samuelson DJ, Traun BD, Devries TL, Haag JD, and Gould MN.  Mechanisms underlying the non-coding breast cancer susceptibility locus MCS5A.  Rat Genomics & Models Annual Meeting, Cold Spring Harbor Laboratory, 2009.
  4. Samuelson DJ, DenDekker AD, and Puckett AH.  Rat Mcs1b is a comparative genetic model of a human breast cancer susceptibility locus.  Poster Presentation, Annual NIEHS P30 Directors' Meeting, University of Pennsylvania, Philadelphia, 2008.
  5. Samuelson DJ.  Rat Mcs1b Is A Genetic Model of A Human Chromosome 5 Breast Cancer Susceptibility Locus.  Poster Presentation, Mammary Gland Biology, Gordon Research Conference, Italy, 2008.
  6. Veillet A, Samuelson DJ, Haag JD, and Gould MN.  Fine-Mapping and Characterization of the Mammary Carcinogenesis Susceptibility Locus, Mcs5c.  Poster Presentation, Era of Hope, Department of Defense Breast Cancer Research Program, 2008.
  7. Gould MN, Samuelson DJ, Smits B, and Haag JD.  Functional Characterization of a Non-Coding Breast Cancer Susceptibility QTL. Oral Presentation, Rat Genomics & Models Annual Meeting, Cold Spring Harbor Laboratory, 2007.
  8. Samuelson DJ, Haag JD, and Gould MN.  Rat Mcs1b maps to a human breast cancer risk allele.  Poster Presentation, Rat Genomics & Models Annual Meeting, Cold Spring Harbor Laboratory, 2007.
  9. Veillet AL, Samuelson DJ, Haag JD, and Gould MN.  The mammary carcinogenesis susceptibility locus Mcs5c has been mapped to a region devoid of known genes. Poster Presentation, Mammary Gland Biology, Gordon Research Conference, 2007.
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