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Doctor of Philosophy in Pharmacology and Toxicology

Major: PHTX
Degree Awarded: Ph.D.
Unit: GE
Program Webpage: http://www.louisville.edu/medschool/pharmacology


Program Information

The Department of Pharmacology & Toxicology is committed to academic excellence and to the attainment of regional, national, and international recognition for the quality of its educational, research, and service activities. Guided by the University of Louisville Challenge for Excellence to become a preeminent metropolitan research university, the Department Strategic Plan will focus on accomplishment of five broad objectives:

  • Provide instruction in pharmacology and toxicology of the highest quality for the education and preparation of medical, dental, nursing, and other health care professional students. Emphasis will be placed on the fundamental principles necessary for life-long learning and the essential knowledge required for rational, effective, and safe use of drug therapy.
  • Advance biomedical knowledge through active contribution to high quality research and other scholarly activities, particularly in pharmacology and toxicology and other areas of focus within the University of Louisville Challenge for Excellence.
  • Provide high quality research and educational experiences in pharmacology and toxicology for the education and training of future biomedical scientists who can provide and advance biomedical education, research, and service.
  • Provide instruction of the highest quality in pharmacology and toxicology that is appropriate for students at the undergraduate, graduate, and postgraduate levels.
  • Provide high quality service to the School of Medicine, the Health Sciences Center, the University, the people of Louisville and the surrounding region, the Commonwealth of Kentucky, professional organizations, the nation, and the world.

Goals of the Program

The Department of Pharmacology and Toxicology is dedicated to advancing biomedical knowledge through active contribution to high quality research in pharmacology and toxicology and to providing high quality research and educational experiences for the education and training of future biomedical scientists who advance biomedical education, research, and service.

Student Financial Support

Students accepted into the Ph.D. program will be considered for financial aid. This aid would include tuition remission, and student health insurance.  The Department houses a NIEHS Predoctoral Training Program in Environmental Health Sciences which provides stipend support for selected students.  Since all Ph.D. students and candidates are considered to be full-time students, they generally are not permitted to seek outside employment while enrolled in the doctoral program.  In cases where financial aid is limited and additional support is essential, students needing outside employment must apply in writing for departmental faculty approval.  The faculty must also approve any change in employment, as well as approving continued outside employment on an annual basis.

Program Admission Procedure

For the Department of Pharmacology and Toxicology complete guidelines are given below.

1. Application forms.  All candidates for admission to graduate programs at the University of Louisville must complete the application form found at http://admissions.louisville.edu/gapp/gapp.html This may be completed online or may be submitted via mail to:

Office of Graduate Admissions
Suite 105, Houchens Bldg
University of Louisville
Louisville, KY 40292
United States of America

Applications are received at any time for starting dates of approximately August 1. All credentials and/or communications should be submitted to the Office of Graduate Admissions and should contain the student's full name and Social Security Number or UofL-issued Student ID. Lack of Social Security Number may cause processing to be delayed. Applications received by January 1 are assured of full consideration for that year. Admission on a conditional basis is a possibility in rare, special cases, even though application materials are incomplete. Please contact the department for additional information.

2. Application Fee.  A $50.00 US currency non-refundable application fee is required with the application form. An application will not be forwarded to the department until this fee is paid. A check or money order should be made payable to the "University of Louisville."

3. Transcripts.  Applicants for admission to a degree program must submit an official transcript from each college attended. All University of Louisville transcripts will automatically be submitted with completion of an application. All applications are considered on an individual basis. Normally, a successful applicant will have an undergraduate GPA of 3.00 or higher and will have successfully completed sufficient coursework in basic biology, chemistry and mathematics.

4. Test Scores.  Applicants normally must take the general section of the Graduate Record Examination (GRE). There is no absolute cutoff score for acceptance. Each case is decided on the totality of its merits. At the discretion of the department, MCAT or other entrance examinations scores may be accepted in place of the GRE. Information can be obtained from:

  • University of Louisville Testing Center, or
  • Graduate Record Examination Educational Testing Service Box 955 Princeton, NJ 08541, or
  • http://www.gre.org/

The GRE Advanced Test in a discipline is not required, but if available will be used in admissions and placement decisions.   NOTE: GRE Institution Code is R1838-University of Louisville. The GRE major codes are 0216 – Pharmacology or 0219 – Toxicology.

5. Statement of Experience and Professional Goals.  At the time of application, a two-three page typed statement should be sent directly to the Department of Pharmacology and Toxicology.  This statement should be used to introduce the student to the faculty of the Department, describing past educational, laboratory and relevant life experiences, as well as outlining professional goals after the degree program. This statement can be sent electronically to jcstates@louisville.edu or via mail to:

 

Director of Graduate Studies
Department of Pharmacology and Toxicology
University of Louisville School of Medicine
Louisville, KY 40292

 

6. English Proficiency.  All applicants for whom English is a second language must also submit official TOEFL scores of 213 or higher on the computer-based test or 550 or higher on the paper-based test for verification of English proficiency. Students holding a bachelor's or advanced degree from an accredited institution in the United States are exempt from this requirement. Information concerning the TOEFL exam can be obtained from: University Testing Center, or Test of English as a Foreign Language PO Box 6151 Princeton, NJ 08541 USA or http://www.toefl.org  The institutional code of UofL for TOEFL is 1838. The TOEFL department code is 30 (other biological sciences.)

7. Personal Interview.  Whenever possible, a personal interview, either in person or via telephone will be held before final offer and acceptance of a position in the Ph.D. program.

8. Letters of Recommendation.  Two letters of recommendation from persons familiar with the applicant's academic work are required. This can be in the form of a letter or may be done using the recommendation form found at http://graduate.louisville.edu/students/grad-rec.pdf.    

9. International Student Applicants.  In addition to satisfying the appropriate credential requirements, applicants may be required to provide the following documents.

  • Applicants who attended college outside the US must submit verbatim notarized English translations of all academic records and credentials.
  • If on a Visa that requires an I-20 or IAP-66, the applicant is required to complete an Application Supplement/Financial Declaration form (http://graduate.louisville.edu/students/international-financial-declaration.html) and submit appropriate financial documentation.
  • A cost estimate is available.

10. Financial Aid.  All applicants to the Ph.D. program of the Department of Pharmacology and Toxicology are automatically considered for financial aid upon admission. Typically, such aid consists of a stipend, tuition remission and a health insurance benefit.   

11. Residency Policy.  Residency status for students is determined in the Office of Graduate Admissions. The status is determined according to the policy on classification of students for fee assessment purposes at state-supported institutions of higher education. Except as provided in the guidelines, it is presumed that a resident has remained in the state in a non-student status for the twelve months immediately preceding the last date for enrollment in the institution.

The domicile of an unemancipated person, as defined in the guidelines, is that of his/her parent. The domicile of a married person is determined by the provisions of the guidelines independent of the residence of the spouse. Copies of the guidelines and appropriate forms for requesting change of residence classification may be obtained from the Office of Student Services.

Indiana Tuition Reciprocity: The University of Louisville is participating in an Indiana Tuition Reciprocity Program for residents of Clark, Crawford, Floyd, Harrison or Scott Counties who have been admitted directly into an approved graduate program. Eligible participants are required to notify the Admissions Office prior to their first enrollment and the Registrar's Office after their first enrollment of any changes in residency status. [e.g. if they no longer live in one of the eligible counties, or are no longer in an eligible program.] The University reserves the right to further investigate and require documentation of eligibility for tuition reciprocity.

For Military Personnel: If an applicant, spouse or parent (if dependent) is currently stationed in Kentucky on military active duty for one or more years, please attach a copy of the military orders, a lease or mortgage showing Kentucky address and a military dependent identification card if appropriate. If the applicant is a Kentucky resident but has been in the military and has been recently discharged, please send a copy of the military discharge papers (DD-214).

International Students on Immigrant/ Permanent Resident Status: If currently on an immigrant/ permanent resident status, it will be necessary to submit a copy of an immigration/ permanent resident card, both sides, for review of possible residency classification for tuition purposes.

The University of Louisville reserves the right to change programs of study, academic requirements, fees, schedules of courses, the announced academic calendar and deadlines without prior notice.

 



Curriculum


Curriculum

Co-Curricular Requirements

Course

Year

Term

Hours

Title

BIOC 645

AY1

Fall

4

Biochemistry I

Diagnostic Exam

PHTX 660

AY1

Fall

4

Principles of Drug and Chemical Action

Receive research descriptions

 from mentors.  Meet to discuss.

PHTX 672/

PHTX 673

AY1

Fall

1 + 1

Research Methods in Pharmacology and Toxicology I  &  II

Rotation selection by August 15

PHTX 619

AY1

Fall

2

Research in Pharmacology

[grade assigned by Grad Committee]

Rotation 1 – Report and lab book

Rotation 2 – Report and lab book

Total

AY1

Fall

12

 

Qualifying Exam I.A

Mentor Selection by end of semester is ideal
 

PHTX  655

AY1

Spring

2

Neuropharmacology

Expectation of full time laboratory participation when not in classroom

BIOC 647

AY1

Spring

4

Biochemistry II

MBIO 667

AY1

Spring

3

Cell Biology

 

PHTX 674/

PHTX 675

AY1

Spring

1 + 1

Research Methods in Pharmacology and Toxicology III & IV

 

PHTX 619

AY1

Spring

1

Research in Pharmacology                           

 [grade assigned by Grad Committee]

 

PHTX 606

AY1

Spring

1

Pharmacology & Toxicology Seminar

 

BIOC 603

AY1

Spring

1

Ethics

Qualifying Exam I.B

Total

AY1

Spring

14

 

With mentor, develop and submit individual curriculum for approval

 

PHTX 619

AY1

Summer

6

Research in Pharmacology      

 [grade assigned by Grad Committee]

Research – semester report and lab book

Total

AY1

Summer

6

 

 

 

PHTX 625

AY2

Fall

2

Scientific Writing

With mentor, create Dissertation Committee, have approved

PHTX 658

AY2

Fall

1

Selective Toxicity and Chemotherapeutics

Expectation of participation in regional forum (e.g.Research!Louisville , SOT)

PHTX 656

AY2

Fall

2

Cardiovascular and Renal Pharmacology

 

PHTX 657

AY2

Fall

2

Endocrine and Metabolic Pharmacology

 

PHTX 619

AY2

Fall

1

Research in Pharmacology        

[grade assigned by Grad Committee]

Submission of outline/draft of research plan as research report

PHTX 606

AY2

Fall

1

Pharmacology & Toxicology Seminar

 

 

AY2

Fall

3

Approved Elective

Qualifying Exam I.C

Total

AY2

Fall

12

 

 

 

PHTX 619

AY2

Spring

5

Research in Pharmacology      

 [grade assigned by Grad Committee]

Qualifying Exam II – Research Plan as Grant Proposal (Due April 1)

PHTX 606

AY2

Spring

1

Pharmacology & Toxicology Seminar

Each year, candidates will present research finding and progress report to department.  Dissertation committee will report concerning progress.  Expectation of annual national / international presentation.

 

AY2

Spring

6

Approved Electives*

Total

AY2

Spring

12

 

DEFENSE of Proposal

Promotion to Candidacy

Expectation of submission of abstract to national of international meeting by end of AY2

Electives

*Example Electives

 

Immunology (from Med Core)

Pathology (from Med Core)

ADV EUKARYOTIC GENETICS

MOLECULAR BIOLOGY

MOLECULAR TOXICOLOGY

PROTEIN STRUCTURE &            FUNCTION

INTRO IMMUNOLOGY

MOLECULAR MICROBIOLOGY

INTEGRATED SYST. PHYSIOL

MOLECULAR NEUROSCIENCE

Various

AYx

Fall

If appropriate, candidates may take elective courses for enrichment

Various

AYx

Spring

AY3-AY5   Research followed by Presentation and Defense of Doctoral Dissertation

TOTAL HOURS

 

54 hrs

[38 classroom + 16 research / seminar/tutorial/lab]



Departmental Faculty


George R. Aronoff
Professor
Professor of Medicine
Gavin E. Arteel
Assistant Professor
Shirish Barve
Associate Professor
Associate Professor of Medicine
Frederick W. Benz
Professor
Aruni Bhatnagar
Professor
Professor of Medicine
Haribabu Bodduluri
Associate Professor
Associate Professor of Microbiology & Immunolog
y
Jian Cai
Instructor
Theresa S. Chen
Professor
Jason A. Chesney
Assistant Professor
Assistant Professor of Medicine
Keith R. Davis
Professor
John W. Eaton
Professor
Professor of Medicine
Paul N. Epstein
Professor
Professor of Pediatrics
Teresa Whei-Mei Fan
Associate Professor
Associate Professor of Chemistry
Richard E. Goldstein
Professor
Professor of Surgery
David Gozal
Professor
Professor of Pediatrics
Evelyne Gozal
Associate Professor
Assistant Professor of Pediatrics
Ramesh C. Gupta
Professor
Theo Hagg
Professor
Professor of Neurological Surgery
David W. Hein
Professor
Chair
Michal Hetman
Assistant Professor
Assistant Professor of Neurological Surgery
Harrell. E. Hurst
Professor
Y. James Kang
Professor
Professor of Medicine
Mary J. Kennedy
Assistant Professor
Assistant Professor of Pediatrics
LaCreis R. Kidd
Assistant Professor
Chi Li
Assistant Professor
Assistant Professor of Medicine
Irene Litvan
Professor
Raymond Lee Lebby Professor in Parkinson’s Disease Research
Manuel Martinez
ProfessorExecutive Vice President for Research
Craig J. McClain
Professor
Professor of Medicine
W. Glenn McGregor
Professor
Associate Professor of Medicine
Kelly M. McMasters
Professor
Professor of Surgery
Donald M. Miller
Professor
Professor of Medicine
Steven R. Myers
Associate Professor
Donald E. Nerland
Professor
Chin Ng
Associate Professor
Associate Professor of Radiology
Kenneth A. Palmer
Associate Professor
William M. Pierce, Jr.
Professor
M. Michele Pisano
Professor
Professor, Birth Defects Center
George C. Rodgers
Professor
Professor of Pediatrics

Peter P. Rowell
Vice Chair for Graduate Education
Professor

Uma Sankar
Assistant Professor
Zhao-Hui Song
Associate Professor
J. Christopher States
Professor
Janice E. Sullivan
Associate Professor Professor of Medicine
David J. Tollerud
Professor
Professor of Environmental & Occupational Toxicology
Leonard C. Waite
Professor
Yang Wang
Associate Professor
Associate Professor of Pediatrics
Brian (Binks) Wattenberg
Associate ProfessorAssociate Professor of Medicine
Walter M. Williams
Professor
Hong Ye Assistant
Assistant Professor
Professor of Medicine
Wolfgang Zacharias
Associate Professor
Associate Professor of Medicine
Wayne S. Zundel
Assistant Professor
Assistant Professor of Radiation Oncology
Michael E. Brier
Professor
Professor of Medicine
Lu Cai
Assistant Professor
Assistant Professor of Medicine
Daniel J. Conklin
Assistant Professor
Assistant Professor of Medicine
Ye Qi Liu
Assistant Professor
Assistant Professor of Pediatrics
Avital Schurr
Professor
Professor of Anesthesiology and Perioperative Medicine
John L. Wong
Professor
Professor of Chemistry
William W. Young
Professor
Professor, Birth Defects Center


Contact Information

Pharmacology and Toxicology - Ph.D.

Peter Rowell, Ph.D.
Vice Chair for Graduate Education
Department of Pharmacology and Toxicology
School of Medicine
University of Louisville
Louisville, KY 40292
United States of America
 

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