Doctor of Philosophy in Pharmacology and Toxicology
Major: PHTXDegree Awarded: Ph.D.
Unit: GE
Program Webpage: http://www.louisville.edu/medschool/pharmacology
Program Information
The Department of Pharmacology & Toxicology is committed to academic excellence and to the attainment of regional, national, and international recognition for the quality of its educational, research, and service activities. Guided by the University of Louisville Challenge for Excellence to become a preeminent metropolitan research university, the Department Strategic Plan will focus on accomplishment of five broad objectives:
- Provide instruction in pharmacology and toxicology of the highest quality for the education and preparation of medical, dental, nursing, and other health care professional students. Emphasis will be placed on the fundamental principles necessary for life-long learning and the essential knowledge required for rational, effective, and safe use of drug therapy.
- Advance biomedical knowledge through active contribution to high quality research and other scholarly activities, particularly in pharmacology and toxicology and other areas of focus within the University of Louisville Challenge for Excellence.
- Provide high quality research and educational experiences in pharmacology and toxicology for the education and training of future biomedical scientists who can provide and advance biomedical education, research, and service.
- Provide instruction of the highest quality in pharmacology and toxicology that is appropriate for students at the undergraduate, graduate, and postgraduate levels.
- Provide high quality service to the School of Medicine, the Health Sciences Center, the University, the people of Louisville and the surrounding region, the Commonwealth of Kentucky, professional organizations, the nation, and the world.
Goals of the Program
The Department of Pharmacology and Toxicology is dedicated to advancing biomedical knowledge through active contribution to high quality research in pharmacology and toxicology and to providing high quality research and educational experiences for the education and training of future biomedical scientists who advance biomedical education, research, and service.
Student Financial Support
Students accepted into the Ph.D. program will be considered for financial aid. This aid would include tuition remission, and student health insurance. The Department houses a NIEHS Predoctoral Training Program in Environmental Health Sciences which provides stipend support for selected students. Since all Ph.D. students and candidates are considered to be full-time students, they generally are not permitted to seek outside employment while enrolled in the doctoral program. In cases where financial aid is limited and additional support is essential, students needing outside employment must apply in writing for departmental faculty approval. The faculty must also approve any change in employment, as well as approving continued outside employment on an annual basis.
Program Admission Procedure
For the Department of Pharmacology and Toxicology complete guidelines are given below.
1. Application forms. All candidates for admission to graduate programs at the University of Louisville must complete the application form found at http://admissions.louisville.edu/gapp/gapp.html This may be completed online or may be submitted via mail to:
Office of Graduate Admissions
Suite 105, Houchens Bldg
University of Louisville
Louisville, KY 40292
United States of America
Applications are received at any time for starting dates of approximately August 1. All credentials and/or communications should be submitted to the Office of Graduate Admissions and should contain the student's full name and Social Security Number or UofL-issued Student ID. Lack of Social Security Number may cause processing to be delayed. Applications received by January 1 are assured of full consideration for that year. Admission on a conditional basis is a possibility in rare, special cases, even though application materials are incomplete. Please contact the department for additional information.
2. Application Fee. A $50.00 US currency non-refundable application fee is required with the application form. An application will not be forwarded to the department until this fee is paid. A check or money order should be made payable to the "University of Louisville."
3. Transcripts. Applicants for admission to a degree program must submit an official transcript from each college attended. All University of Louisville transcripts will automatically be submitted with completion of an application. All applications are considered on an individual basis. Normally, a successful applicant will have an undergraduate GPA of 3.00 or higher and will have successfully completed sufficient coursework in basic biology, chemistry and mathematics.
4. Test Scores. Applicants normally must take the general section of the Graduate Record Examination (GRE). There is no absolute cutoff score for acceptance. Each case is decided on the totality of its merits. At the discretion of the department, MCAT or other entrance examinations scores may be accepted in place of the GRE. Information can be obtained from:
- University of Louisville Testing Center, or
- Graduate Record Examination Educational Testing Service Box 955 Princeton, NJ 08541, or
- http://www.gre.org/
The GRE Advanced Test in a discipline is not required, but if available will be used in admissions and placement decisions. NOTE: GRE Institution Code is R1838-University of Louisville. The GRE major codes are 0216 – Pharmacology or 0219 – Toxicology.
5. Statement of Experience and Professional Goals. At the time of application, a two-three page typed statement should be sent directly to the Department of Pharmacology and Toxicology. This statement should be used to introduce the student to the faculty of the Department, describing past educational, laboratory and relevant life experiences, as well as outlining professional goals after the degree program. This statement can be sent electronically to jcstates@louisville.edu or via mail to:
Director of Graduate Studies
Department of Pharmacology and Toxicology
University of Louisville School of Medicine
Louisville, KY 40292
6. English Proficiency. All applicants for whom English is a second language must also submit official TOEFL scores of 213 or higher on the computer-based test or 550 or higher on the paper-based test for verification of English proficiency. Students holding a bachelor's or advanced degree from an accredited institution in the United States are exempt from this requirement. Information concerning the TOEFL exam can be obtained from: University Testing Center, or Test of English as a Foreign Language PO Box 6151 Princeton, NJ 08541 USA or http://www.toefl.org The institutional code of UofL for TOEFL is 1838. The TOEFL department code is 30 (other biological sciences.)
7. Personal Interview. Whenever possible, a personal interview, either in person or via telephone will be held before final offer and acceptance of a position in the Ph.D. program.
8. Letters of Recommendation. Two letters of recommendation from persons familiar with the applicant's academic work are required. This can be in the form of a letter or may be done using the recommendation form found at http://graduate.louisville.edu/students/grad-rec.pdf.
9. International Student Applicants. In addition to satisfying the appropriate credential requirements, applicants may be required to provide the following documents.
- Applicants who attended college outside the US must submit verbatim notarized English translations of all academic records and credentials.
- If on a Visa that requires an I-20 or IAP-66, the applicant is required to complete an Application Supplement/Financial Declaration form (http://graduate.louisville.edu/students/international-financial-declaration.html) and submit appropriate financial documentation.
- A cost estimate is available.
10. Financial Aid. All applicants to the Ph.D. program of the Department of Pharmacology and Toxicology are automatically considered for financial aid upon admission. Typically, such aid consists of a stipend, tuition remission and a health insurance benefit.
11. Residency Policy. Residency status for students is determined in the Office of Graduate Admissions. The status is determined according to the policy on classification of students for fee assessment purposes at state-supported institutions of higher education. Except as provided in the guidelines, it is presumed that a resident has remained in the state in a non-student status for the twelve months immediately preceding the last date for enrollment in the institution.
The domicile of an unemancipated person, as defined in the guidelines, is that of his/her parent. The domicile of a married person is determined by the provisions of the guidelines independent of the residence of the spouse. Copies of the guidelines and appropriate forms for requesting change of residence classification may be obtained from the Office of Student Services.
Indiana Tuition Reciprocity: The University of Louisville is participating in an Indiana Tuition Reciprocity Program for residents of Clark, Crawford, Floyd, Harrison or Scott Counties who have been admitted directly into an approved graduate program. Eligible participants are required to notify the Admissions Office prior to their first enrollment and the Registrar's Office after their first enrollment of any changes in residency status. [e.g. if they no longer live in one of the eligible counties, or are no longer in an eligible program.] The University reserves the right to further investigate and require documentation of eligibility for tuition reciprocity.
For Military Personnel: If an applicant, spouse or parent (if dependent) is currently stationed in Kentucky on military active duty for one or more years, please attach a copy of the military orders, a lease or mortgage showing Kentucky address and a military dependent identification card if appropriate. If the applicant is a Kentucky resident but has been in the military and has been recently discharged, please send a copy of the military discharge papers (DD-214).
International Students on Immigrant/ Permanent Resident Status: If currently on an immigrant/ permanent resident status, it will be necessary to submit a copy of an immigration/ permanent resident card, both sides, for review of possible residency classification for tuition purposes.
The University of Louisville reserves the right to change programs of study, academic requirements, fees, schedules of courses, the announced academic calendar and deadlines without prior notice.
Curriculum
Curriculum | Co-Curricular Requirements | |||||||||
Course | Year | Term | Hours | Title | ||||||
BIOC 645 | AY1 | Fall | 4 | Biochemistry I | Diagnostic Exam | |||||
PHTX 660 | AY1 | Fall | 4 | Principles of Drug and Chemical Action | Receive research descriptions from mentors. Meet to discuss. | |||||
PHTX 672/ PHTX 673 | AY1 | Fall | 1 + 1 | Research Methods in Pharmacology and Toxicology I & II | Rotation selection by August 15 | |||||
PHTX 619 | AY1 | Fall | 2 | Research in Pharmacology [grade assigned by Grad Committee] | Rotation 1 – Report and lab book Rotation 2 – Report and lab book | |||||
Total | AY1 | Fall | 12 |
| Qualifying Exam I.A | |||||
| Mentor Selection by end of semester is ideal | ||||||||||
PHTX 655 | AY1 | Spring | 2 | Neuropharmacology | Expectation of full time laboratory participation when not in classroom | |||||
BIOC 647 | AY1 | Spring | 4 | Biochemistry II | ||||||
MBIO 667 | AY1 | Spring | 3 |
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PHTX 674/ PHTX 675 | AY1 | Spring | 1 + 1 | Research Methods in Pharmacology and Toxicology III & IV |
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PHTX 619 | AY1 | Spring | 1 | Research in Pharmacology [grade assigned by Grad Committee] |
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PHTX 606 | AY1 | Spring | 1 | Pharmacology & Toxicology Seminar |
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BIOC 603 | AY1 | Spring | 1 | Ethics | Qualifying Exam I.B | |||||
Total | AY1 | Spring | 14 |
| With mentor, develop and submit individual curriculum for approval | |||||
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PHTX 619 | AY1 | Summer | 6 | Research in Pharmacology [grade assigned by Grad Committee] | Research – semester report and lab book | |||||
Total | AY1 | Summer | 6 |
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PHTX 625 | AY2 | Fall | 2 | Scientific Writing | With mentor, create Dissertation Committee, have approved | |||||
PHTX 658 | AY2 | Fall | 1 | Selective Toxicity and Chemotherapeutics | Expectation of participation in regional forum (e.g.Research!Louisville , SOT) | |||||
PHTX 656 | AY2 | Fall | 2 | Cardiovascular and Renal Pharmacology |
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PHTX 657 | AY2 | Fall | 2 | Endocrine and Metabolic Pharmacology |
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PHTX 619 | AY2 | Fall | 1 | Research in Pharmacology [grade assigned by Grad Committee] | Submission of outline/draft of research plan as research report | |||||
PHTX 606 | AY2 | Fall | 1 | Pharmacology & Toxicology Seminar |
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| AY2 | Fall | 3 | Approved Elective | Qualifying Exam I.C | |||||
Total | AY2 | Fall | 12 |
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PHTX 619 | AY2 | Spring | 5 | Research in Pharmacology [grade assigned by Grad Committee] | Qualifying Exam II – Research Plan as Grant Proposal (Due April 1) | |||||
PHTX 606 | AY2 | Spring | 1 | Pharmacology & Toxicology Seminar | Each year, candidates will present research finding and progress report to department. Dissertation committee will report concerning progress. Expectation of annual national / international presentation. | |||||
| AY2 | Spring | 6 | Approved Electives* | ||||||
Total | AY2 | Spring | 12 |
| DEFENSE of Proposal | |||||
Promotion to Candidacy | Expectation of submission of abstract to national of international meeting by end of AY2 | |||||||||
Electives | *Example Electives
Immunology (from Med Core) Pathology (from Med Core) MOLECULAR TOXICOLOGY | PROTEIN STRUCTURE & FUNCTION | ||||||||
Various | AYx | Fall | If appropriate, candidates may take elective courses for enrichment | |||||||
Various | AYx | Spring | ||||||||
AY3-AY5 Research followed by Presentation and Defense of Doctoral Dissertation | ||||||||||
TOTAL HOURS |
| 54 hrs | [38 classroom + 16 research / seminar/tutorial/lab] | |||||||
Departmental Faculty
| George R. Aronoff Professor Professor of Medicine |
| Gavin E. Arteel Assistant Professor |
| Shirish Barve Associate Professor Associate Professor of Medicine |
| Frederick W. Benz Professor |
| Aruni Bhatnagar Professor Professor of Medicine |
| Haribabu Bodduluri Associate Professor Associate Professor of Microbiology & Immunology |
| Jian Cai Instructor |
| Theresa S. Chen Professor |
| Jason A. Chesney Assistant Professor Assistant Professor of Medicine |
| Keith R. Davis Professor |
| John W. Eaton Professor Professor of Medicine |
| Paul N. Epstein Professor Professor of Pediatrics |
| Teresa Whei-Mei Fan Associate Professor Associate Professor of Chemistry |
| Richard E. Goldstein Professor Professor of Surgery |
| David Gozal Professor Professor of Pediatrics |
| Evelyne Gozal Associate Professor Assistant Professor of Pediatrics |
| Ramesh C. Gupta Professor |
| Theo Hagg Professor Professor of Neurological Surgery |
| David W. Hein Professor Chair |
| Michal Hetman Assistant Professor Assistant Professor of Neurological Surgery |
| Harrell. E. Hurst Professor |
| Y. James Kang Professor Professor of Medicine |
| Mary J. Kennedy Assistant Professor Assistant Professor of Pediatrics |
| LaCreis R. Kidd Assistant Professor |
| Chi Li Assistant Professor Assistant Professor of Medicine |
| Irene Litvan Professor Raymond Lee Lebby Professor in Parkinson’s Disease Research |
| Manuel Martinez ProfessorExecutive Vice President for Research |
| Craig J. McClain Professor Professor of Medicine |
| W. Glenn McGregor Professor Associate Professor of Medicine |
| Kelly M. McMasters Professor Professor of Surgery |
| Donald M. Miller Professor Professor of Medicine |
| Steven R. Myers Associate Professor |
| Donald E. Nerland Professor |
| Chin Ng Associate Professor Associate Professor of Radiology |
| Kenneth A. Palmer Associate Professor |
| William M. Pierce, Jr. Professor |
| M. Michele Pisano Professor Professor, Birth Defects Center |
| George C. Rodgers Professor Professor of Pediatrics |
Peter P. Rowell |
| Uma Sankar Assistant Professor |
| Zhao-Hui Song Associate Professor |
| J. Christopher States Professor |
| Janice E. Sullivan Associate Professor Professor of Medicine |
| David J. Tollerud Professor Professor of Environmental & Occupational Toxicology |
| Leonard C. Waite Professor |
| Yang Wang Associate Professor Associate Professor of Pediatrics |
| Brian (Binks) Wattenberg Associate ProfessorAssociate Professor of Medicine |
| Walter M. Williams Professor |
| Hong Ye Assistant Assistant Professor Professor of Medicine |
| Wolfgang Zacharias Associate Professor Associate Professor of Medicine |
| Wayne S. Zundel Assistant Professor Assistant Professor of Radiation Oncology |
| Michael E. Brier Professor Professor of Medicine |
| Lu Cai Assistant Professor Assistant Professor of Medicine |
| Daniel J. Conklin Assistant Professor Assistant Professor of Medicine |
| Ye Qi Liu Assistant Professor Assistant Professor of Pediatrics |
| Avital Schurr Professor Professor of Anesthesiology and Perioperative Medicine |
| John L. Wong Professor Professor of Chemistry |
| William W. Young Professor Professor, Birth Defects Center |